Science China Materials最新文献

{"title":"Low-cost Mn-based P2/O3 heterostructured layered oxide cathodes based on orbital-lattice synergistic modulation strategy for sodium-ion batteries","authors":"Jun-Xu Guo \u0000 (,&nbsp;),&nbsp;Zhuang-Chun Jian \u0000 (,&nbsp;),&nbsp;Yan-Fang Zhu \u0000 (,&nbsp;),&nbsp;Qi-Cong Ling \u0000 (,&nbsp;),&nbsp;Meng-Ying Li \u0000 (,&nbsp;),&nbsp;Xin-Yu Liu \u0000 (,&nbsp;),&nbsp;Hanshen Xin \u0000 (,&nbsp;),&nbsp;Yao Xiao \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3567-x","DOIUrl":"10.1007/s40843-025-3567-x","url":null,"abstract":"<div><p>Manganese-based (Mn-based) layered oxides have become the prospective cathode options for sodium-ion batteries (SIBs) due to the high theoretical capacity and low cost. However, the Mn³⁺ (high spin state) accumulated in Na⁺ intercalation/deintercalation is susceptible to inducing a severe Jahn-Teller effect in the octahedral coordination, leading to irreversible phase transitions and lattice deformations. Herein, we designed a series of Ti-substitution P2/O3 heterostructured cathode materials, and innovated an orbital-lattice synergistic modulation strategy to effectively boost the structural stability of the materials. <i>In situ</i> X-ray diffraction (<i>in situ</i> XRD) patterns indicated that the coupling effect between the P2/O3 biphasic structure effectively inhibits the irreversible phase transitions of P2 to O2 at high voltages. Synchrotron X-ray absorption spectroscopy (XAS) analysis shows that the d⁰ electronic configuration of Ti⁴⁺ eliminates the degenerate electronic states inherent in the d⁴ configuration of Mn³⁺, effectively suppressing Jahn-Teller distortion. Accordingly, the optimized P2/O3-Na_0.85Mn_0.95Ti_0.05O₂ (NMT-05) electrode exhibits remarkable energy density and kinetic properties in both the half-cell system and full-cell systems that matched with a hard carbon anode. This work could offer guidelines for exploiting low-cost and highly stable practical Mn-based oxide cathode materials.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 10","pages":"3685 - 3694"},"PeriodicalIF":7.4,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145248264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Star-shaped cross-linkable hole transport materials with high triplet energy and deep HOMO energy enable efficient solution-processed deep-blue TADF OLEDs","authors":"Jiaxu Bai \u0000 (,&nbsp;),&nbsp;Jingyuan Feng \u0000 (,&nbsp;),&nbsp;Chuanxin Liao \u0000 (,&nbsp;),&nbsp;Tianhao Wang \u0000 (,&nbsp;),&nbsp;Shirong Wang \u0000 (,&nbsp;),&nbsp;Hongli Liu \u0000 (,&nbsp;),&nbsp;Xianggao Li \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3638-2","DOIUrl":"10.1007/s40843-025-3638-2","url":null,"abstract":"<div><p>Cross-linkable hole transport materials (x-HTMs) play a crucial role in solving the issue of interlayer mixing of solution-processed organic light-emitting diodes (OLEDs). However, issues such as energy level mismatch and low hole mobility hinder the application of x-HTMs in deep-blue OLEDs. In particular, thermally activated delayed fluorescent (TADF) emitters require HTMs with high triplet energies (<i>E</i>_T) to ensure high exciton utilization efficiency. Here, two star-shaped cross-linkable HTMs 5-(9<i>H</i>-carbazol-9-yl)-<i>N</i>¹,<i>N</i>³-di(<i>p</i>-tolyl)-<i>N</i>¹,<i>N</i>³-bis(4-vinylphenyl)benzene-1,3-diamine (m-V-CzDPA) and <i>N</i>¹,<i>N</i>¹-diphenyl-<i>N</i>³,<i>N</i>⁵-di(<i>p</i>-tolyl)-<i>N</i>³,<i>N</i>⁵-bis(4-vinylphenyl) benzene-1,3,5-triamine (m-V-DPADPA) were designed and synthesized. Owing to their aromatic torsion structures, m-V-CzDPA and m-V-DPADPA possessed high <i>E</i>_Ts of 2.89 and 2.87 eV, respectively, which can effectively confine triplet excitons in the emitting layer (EML). The carrier diffusion coefficients of their x-HTMs, x-m-CzDPA and x-m-DPADPA, which were obtained via carrier diffusion imaging characterization were 0.54 and 0.44 cm² s⁻¹, respectively, thus indicating outstanding intrinsic hole transport capacity, with hole mobilities of 4.30×10⁻⁴ and 1.39×10⁻⁴ cm² V⁻¹ s⁻¹, respectively. Solution-processed deep-blue TADF-OLEDs employing x-m-CzDPA as the HTM achieved a maximum current efficiency/maximum external quantum efficiency of 5.25 cd A⁻¹/18.06%, with CIE coordinates of (0.162, 0.042). This is the first time that x-HTMs have served as efficient deep-blue TADF-OLEDs via a solution process, which also meets the latest BT. 2020 standard (CIE_<i>y</i> ⩽ 0.046).</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3239 - 3249"},"PeriodicalIF":7.4,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stretchable and low-voltage electrolyte gate organic thin film transistors based on ionic gel for glucose sensing","authors":"Hongchen Jiang \u0000 (,&nbsp;),&nbsp;Xiaoying Zhang \u0000 (,&nbsp;),&nbsp;Xiangxiang Li \u0000 (,&nbsp;),&nbsp;Yan Wang \u0000 (,&nbsp;),&nbsp;Weiyu Wang \u0000 (,&nbsp;),&nbsp;Xin Ye \u0000 (,&nbsp;),&nbsp;Hui Yang \u0000 (,&nbsp;),&nbsp;Wenping Hu \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3632-9","DOIUrl":"10.1007/s40843-025-3632-9","url":null,"abstract":"<div><p>Stretchable extended-gate organic thin film transistor (OTFT) not only retains the high selectivity inherent to electrochemical sensing but also integrates the intrinsic flexibility and <i>in situ</i> signal amplification capabilities of stretchable organic thin film transistors. This design significantly reduces the signal processing burden at the backend, enhances signal sensitivity, and extends the detection limit, demonstrating great potential for wearable sweat sensors. However, the widespread adoption of stretchable OTFT in wearable electronics has been hindered by their high operating voltages and limited operational stability. Here, a stretchable ionic gel was proposed as the dielectric layer, enabling the fabrication of intrinsically stretchable electrolyte gate organic thin film transistor (EGOTFT) with ultralow operating voltages (&lt;1 V). The resulting devices exhibited a remarkably low operating voltage of −0.5 V, excellent long-term stability (over 30 days), and a steep subthreshold slope of 98 mV dec⁻¹. Meanwhile, the stretchable EGOTFT demonstrated high mechanical durability, maintaining stable electrical performance under 40% strain and after 10⁴ stretching-releasing cycles. Based on this EGOTFT architecture, a wearable glucose sensor was realized, meeting the safety and conformability requirements for wearable biomedical applications. This work opens a new opportunity for e-skin with signal-identification capabilities.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3368 - 3376"},"PeriodicalIF":7.4,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A dual-dynamically crosslinked hydrogel for cardiac repair with microenvironment regulation and angiogenic functions","authors":"Haitao Zhang \u0000 (,&nbsp;),&nbsp;Lei Liang \u0000 (,&nbsp;),&nbsp;Zhiwei Yue \u0000 (,&nbsp;),&nbsp;Chengyao Wang \u0000 (,&nbsp;),&nbsp;Linyu Chen \u0000 (,&nbsp;),&nbsp;Jiajun Lu \u0000 (,&nbsp;),&nbsp;Hong Zhang \u0000 (,&nbsp;),&nbsp;Fanglian Yao \u0000 (,&nbsp;),&nbsp;Hong Sun \u0000 (,&nbsp;),&nbsp;Junjie Li \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3619-1","DOIUrl":"10.1007/s40843-025-3619-1","url":null,"abstract":"<div><p>Inflammation and ischemic microenvironments represent significant challenges in cardiac repair. To address these issues, we developed a series of dual-dynamically crosslinked alginate-based hydrogels (SA-PBA/E/Sr) containing strontium ions (Sr²⁺) and epigallocatechin gallate (EGCG), which demonstrate microenvironment modulation and angiogenic capabilities in the myocardial infarction (MI) microenvironment. In the SA-PBA/E/Sr hydrogel system, alginate modified with aminophenylboronic acid (PBA) was synthesized to form boronic acid ester bonds with EGCG and an ionic coordination network with Sr²⁺ ions. The resulting hydrogel exhibits excellent injectability due to its dual-dynamically crosslinked structure, with its formation and mechanical properties being tunable modulated by the PBA substitution degree, EGCG concentration, and Sr²⁺ content. The incorporation of EGCG enables the hydrogel to efficiently scavenge reactive oxygen species (ROS) and mitigate oxidative stress-induced cellular damage under hypoxia. Furthermore, the introduction of Sr²⁺ significantly enhances the migratory capacity of endothelial cells, a critical factor in angiogenesis. <i>In vivo</i> experiments revealed that the injection of SA-PBA/E/Sr hydrogel into the infarcted myocardium of Sprague-Dawley (SD) rats led to reduced ROS levels, alleviated inflammatory responses, suppression of pro-inflammatory M1 macrophage expression, enhancement of anti-inflammatory M2 macrophage expression, and accelerated neovascularization in the damaged tissue. Echocardiographic and histological analyses demonstrated a remarkable increase in ejection fraction and a decreased infarct size, collectively indicating significant cardiac functional recovery.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3377 - 3389"},"PeriodicalIF":7.4,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interface engineering in hexagonal boron nitride/metal systems: from in situ growth to metal matrix composites","authors":"Jian Yang \u0000 (,&nbsp;),&nbsp;Shaoqiang Zhu \u0000 (,&nbsp;),&nbsp;Dongdong Zhao \u0000 (,&nbsp;),&nbsp;Xudong Rong \u0000 (,&nbsp;),&nbsp;Xiang Zhang \u0000 (,&nbsp;),&nbsp;Naiqin Zhao \u0000 (,&nbsp;),&nbsp;Chunnian He \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3592-5","DOIUrl":"10.1007/s40843-025-3592-5","url":null,"abstract":"<div><p>Hexagonal boron nitride (h-BN) exhibits unique physicochemical properties, and the interfaces it forms with metals are crucial for the development of next-generation electronic devices, catalysts, and high-performance composite materials. This review focuses on interface engineering within h-BN/metal systems, systematically analyzing the interfacial characteristics associated with two primary approaches: <i>in situ</i> growth and <i>ex situ</i> compositing. Specifically, during the <i>in situ</i> growth of h-BN thin films on metal substrates, the metal substrate and growth conditions exert multifaceted influences on film quality through interfacial coupling. For <i>ex situ</i> preparation of h-BN/metal composites, interface construction is synergistically determined by h-BN dimension, matrix properties, and the fabrication process. This review aims to elucidate the fundamental principles and unique mechanisms of h-BN/metal interface control, thereby providing strategic insights for the designing and optimizing advanced h-BN-based functional devices and composite materials.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3114 - 3142"},"PeriodicalIF":7.4,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reversible modulation of circularly polarized luminescence in chiral molecular cage-based supramolecular assemblies","authors":"Jianqiu Li \u0000 (,&nbsp;),&nbsp;Ran-Qi Chen \u0000 (,&nbsp;),&nbsp;Taowei Zhu \u0000 (,&nbsp;),&nbsp;Xiaoyan Wang \u0000 (,&nbsp;),&nbsp;Xiaonian Xue \u0000 (,&nbsp;),&nbsp;Huang Wu \u0000 (,&nbsp;),&nbsp;Dechao Geng \u0000 (,&nbsp;),&nbsp;Yu Wang \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3611-3","DOIUrl":"10.1007/s40843-025-3611-3","url":null,"abstract":"<div><p>Supramolecular materials exhibiting reversible circularly polarized luminescence (CPL) are of great interest for their potential applications in the development of 3D display technology and information encryption. In this work, we synthesize a pair of molecular cage enantiomers constructed from (2<i>R</i>)/(2<i>S</i>)-diaminocyclohexane-functionalized naphthalenediimide units ((4<i>R</i>/<i>S</i>)Cy-NDIDA) and fluorescent tris(4-formylphenyl)amine (TPA) components. The cage exhibits extremely weak fluorescence emission in both liquid and solid states. Notably, the introduction of tris(pentafluorophenyl)borane (TFPB) as a guest molecule gradually activates the photoluminescence (PL) and CPL signals of the chiral cage via host-guest interaction. Furthermore, photochromic diarylethene (DAE) is incorporated into the system. The reversible isomerization of DAE under light irradiation enables dynamic control of Förster resonance energy transfer (FRET) interactions with the host-guest complex, resulting in switchable fluorescence quenching and recovery. This precise strategy for controlling dynamic CPL switching of the chiral molecular cage offers a novel strategy for the development of supramolecular CPL systems.\u0000</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3229 - 3238"},"PeriodicalIF":7.4,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heterointerface engineering via controlled nitridation enables GHz-to-THz broadband electromagnetic wave absorption in Mo1.33B2Tx nanosheets","authors":"Wenxuan Wang \u0000 (,&nbsp;),&nbsp;Hongyun Qin \u0000 (,&nbsp;),&nbsp;Hongyu Li \u0000 (,&nbsp;),&nbsp;Di Lan \u0000 (,&nbsp;),&nbsp;Yuxuan Wang \u0000 (,&nbsp;),&nbsp;Yuxuan Han \u0000 (,&nbsp;),&nbsp;Dong Liu \u0000 (,&nbsp;),&nbsp;Ransheng Liu \u0000 (,&nbsp;),&nbsp;Guanglei Wu \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3624-y","DOIUrl":"10.1007/s40843-025-3624-y","url":null,"abstract":"<div><p>MBene materials, as emerging two-dimensional (2D) transition metal borides, exhibit exceptional potential for electromagnetic (EM) wave absorption due to their high conductivity and tunable surface properties. However, their structural instability and limited EM absorption efficiency in the gigahertz (GHz) or terahertz (THz) band remain critical challenges. Controlled nitridation enables the construction of heterogeneous interfaces, providing an effective strategy for precisely tailoring EM absorption properties. Herein, through NH₃ annealing of exfoliated Mo_1.33B₂T_<i>x</i> nanosheets, we engineered a hierarchical nanoflower morphology with MoN/MoB heterointerfaces, which synergistically enhanced dielectric loss and impedance matching. The optimized Mo_1.33B₂T_<i>x</i>-650 absorber achieved a record minimum reflection loss (RL_min) of −61.4 dB and a broad effective absorption bandwidth across key GHz frequencies. Notably, monolayer Mo_1.33B₂T_<i>x</i> nanosheets simultaneously exhibited ultrahigh THz wave absorption (94.54% at 0.5–3.8 THz) and near-perfect visible transparency (99.12%), unlocking unprecedented potential for transparent optoelectronic devices. Combined with superior thermal and mechanical properties, this study establishes a generalizable paradigm for designing multifunctional MBene-based absorbers operating across GHz to THz spectra.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 10","pages":"3757 - 3766"},"PeriodicalIF":7.4,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145248266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-mode photochromic luminescence of carbon dots induced by photoinduced electron transfer","authors":"Jueran Cao \u0000 (,&nbsp;),&nbsp;Enlin Huang \u0000 (,&nbsp;),&nbsp;Ziting Zhong \u0000 (,&nbsp;),&nbsp;Tingjie Jiang \u0000 (,&nbsp;),&nbsp;Haoran Zhang \u0000 (,&nbsp;),&nbsp;Wei Li \u0000 (,&nbsp;),&nbsp;Xuejie Zhang \u0000 (,&nbsp;),&nbsp;Chaofan Hu \u0000 (,&nbsp;),&nbsp;Bingfu Lei \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3555-y","DOIUrl":"10.1007/s40843-025-3555-y","url":null,"abstract":"<div><p>The integration of photochromism and photoluminescence in functional materials presents significant challenges, particularly in achieving broad-spectrum color modulation and rapid response. In this work, we have developed sodium-doped and sodium/boron co-doped CDs that exhibit dual-mode photochromic luminescent behavior through a novel radical-mediated mechanism. The Na-CDs demonstrated a 180 nm red-shift in emission, transitioning from 450 to 630 nm. The Na, B-CDs achieved blue-shifted, multicolor emission, progressing from orange to yellow and green under 30-s UV irradiation. Notably, the photochromic states spontaneously reverted to their initial configurations without external stimuli. These phenomena arise from photoinduced electron transfer between pristine CDs and light-generated anionic radicals. Leveraging these unique photochromic properties, we implemented reversible anti-counter-feiting systems and information encryption platforms. Furthermore, the photochromic CDs exhibit daylight-responsive UV detection capabilities and are functional in plant cell imaging, significantly expanding their potential applications in optoelectronic devices.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 10","pages":"3591 - 3599"},"PeriodicalIF":7.4,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145248174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodegradable hollow MOFs-based nano-modulator for collaboratively blocking energy metabolism for immunotherapy of orthotopic gliomas","authors":"Shiqi Bai \u0000 (,&nbsp;),&nbsp;Hongya Zhang \u0000 (,&nbsp;),&nbsp;Rong Mou \u0000 (,&nbsp;),&nbsp;Shaopeng Zhang \u0000 (,&nbsp;),&nbsp;Na Yin \u0000 (,&nbsp;),&nbsp;Yue Cao \u0000 (,&nbsp;),&nbsp;Wanying Li \u0000 (,&nbsp;),&nbsp;Ziqian Wang \u0000 (,&nbsp;),&nbsp;Bin Wang \u0000 (,&nbsp;),&nbsp;Donghao Qu \u0000 (,&nbsp;),&nbsp;Shuyan Song \u0000 (,&nbsp;),&nbsp;Yunqian Li \u0000 (,&nbsp;),&nbsp;Xinrui Liu \u0000 (,&nbsp;),&nbsp;Yanfang Jiang \u0000 (,&nbsp;),&nbsp;Yinghui Wang \u0000 (,&nbsp;),&nbsp;Hongjie Zhang \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3484-6","DOIUrl":"10.1007/s40843-025-3484-6","url":null,"abstract":"<div><p>The immunosuppressive tumor microenvironment (TME) of gliomas makes their treatment consistently suboptimal, and the aberrant energy metabolism of glioma cells orchestrates tumorigenesis and the immunosuppressive TME. In this work, we construct a biodegradable nano-modulator (ZIF-90@MnO₂@GPNA, ZMG) based on ZIF-90 decorated by MnO₂ and loaded with glutamine transport antagonist (L-γ-glutamyl-<i>p</i>-nitroanilide, GPNA) for efficiently gliomas therapy by multi-pathways inhibition of energy metabolism and reshaping TME. In order to efficiently cross the blood-brain barrier (BBB) and target the gliomas, hyaluronic acid (HA) and lactoferrin (Lf) are further functionalized on its surface (ZIF-90@MnO₂@GPNA@HA-Lf, ZMGH-Lf). ZMGH-Lf biodegrades in response to stimulation of TME, releasing Mn²⁺, which can catalyze H₂O₂ to ·OH and lead to mitochondrial dysfunction. ZMGH-Lf can inhibit glycolysis by alleviating hypoxia and reducing NAD⁺ expression, while loaded GPNA inhibits the compensatory increase in glutamine uptake. This therapeutic strategy not only achieves a multi-pathway disruption of glioma metabolism, but also relieves the immune resistance and improves the immune TME. All these findings demonstrate that ZMGH-Lf can effectively inhibit gliomas by multi-ways manipulation of energy metabolism and immunotherapy, which provides a new strategy for the treatment of gliomas.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 10","pages":"3819 - 3830"},"PeriodicalIF":7.4,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145248365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organic cocrystals in the NIR window: functional design, controlled synthesis and frontier applications","authors":"Rui Shi \u0000 (,&nbsp;),&nbsp;Wanglong Hong \u0000 (,&nbsp;),&nbsp;Shengli Zhu \u0000 (,&nbsp;),&nbsp;Zhenduo Cui \u0000 (,&nbsp;),&nbsp;Zhaoyang Li \u0000 (,&nbsp;),&nbsp;Shuilin Wu \u0000 (,&nbsp;),&nbsp;Wence Xu \u0000 (,&nbsp;),&nbsp;Zhonghui Gao \u0000 (,&nbsp;),&nbsp;Yanqin Liang \u0000 (,&nbsp;),&nbsp;Hui Jiang \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3546-5","DOIUrl":"10.1007/s40843-025-3546-5","url":null,"abstract":"<div><p>As an emerging functional material system, organic cocrystals in the near-infrared (NIR) window drive the innovation of novel material systems. In recent years, it has made breakthroughs in optoelectronics, energy conversion, and biomedicine, thanks to its unique molecular assembly strategy, charge-transfer characteristics, and multi-dimensional application potential. This paper systematically reviews the design strategies, preparation methods, structure relationships, characterization methods, and cutting-edge applications of this type of material. Finally, it presents prospects for future research directions and challenges.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"2999 - 3018"},"PeriodicalIF":7.4,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}