Science China Materials最新文献

{"title":"Vision system utilizing large-area organic single crystals for sensory applications","authors":"Lihua He \u0000 (,&nbsp;),&nbsp;Yi Zou \u0000 (,&nbsp;),&nbsp;Chengtai Li \u0000 (,&nbsp;),&nbsp;Shuming Duan \u0000 (,&nbsp;),&nbsp;Xiaochen Ren \u0000 (,&nbsp;),&nbsp;Wenping Hu \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3641-y","DOIUrl":"10.1007/s40843-025-3641-y","url":null,"abstract":"<div><p>The development of brain-inspired neural network computing synaptic devices based on organic field-effect transistors (OFETs) represents a pivotal research frontier in neuromorphic computing and flexible electronics. These devices elucidate fundamental mechanistic parallels between biological neural networks and artificial systems, facilitating the paradigm shift in organic electronics from passive “sensing” to active “cognition”. This technological evolution enables loop perception-computation-decision architectures while unlocking transformative opportunities in intelligent hardware and medical technologies. Such pioneering advancements are poised to redefine the global semiconductor industry landscape by bridging neuromorphic engineering with next-generation bioelectronic applications, ultimately driving the convergence of adaptive learning systems and human-machine symbiotic interfaces. A low-voltage (1 V) C₈-BTBT optoelectronic synaptic array (coefficient of variation in synaptic weight modulation: 8%) emulated human visual information processing under distinct cognitive states: dispersed-attention mode achieved rapid response and short-term plasticity, while focused-attention mode enabled noise suppression and long-term potentiation via carrier trapping modulation. This platform advances hardware-level perception-computation integration for biomimetic vision chips.\u0000</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3401 - 3408"},"PeriodicalIF":7.4,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advances in layer engineering and controllable fabrication of graphene, h-BN, and transition metal dichalcogenides","authors":"Aiqing Fan \u0000 (,&nbsp;),&nbsp;Qing Zhang \u0000 (,&nbsp;),&nbsp;Yongshuai Wang \u0000 (,&nbsp;),&nbsp;Lin Li \u0000 (,&nbsp;),&nbsp;Fan Wu \u0000 (,&nbsp;),&nbsp;Dechao Geng \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3656-9","DOIUrl":"10.1007/s40843-025-3656-9","url":null,"abstract":"<div><p>Multilayer two-dimensional (2D) materials offer expanded opportunities for tuning electronic, optical, and quantum properties compared to their monolayer forms. The number of layers, stacking configuration, and interlayer interactions are critical parameters that govern the physical behavior of these materials, enabling unique functionalities such as tunable bandgaps, interlayer excitons, sliding ferroelectricity, and unconventional superconductivity. This review highlights recent progress in the precise fabrication techniques of multilayer graphene, h-BN, and transition metal dichalcogenides. We compare artificial assembly techniques and direct growth strategies (chemical vapor deposition), emphasizing their advantages, limitations, and progress toward achieving uniform thickness, high crystallinity, and clean interfaces. The ability to engineer multilayer structures plays an essential role in improving device performance and realizing new quantum states of matter. By discussing fabrication strategies, growth mechanisms, and interlayer coupling effects, we highlight the significance of multilayer architecture in the development of functional 2D material systems.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3143 - 3170"},"PeriodicalIF":7.4,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preface: celebrating the 130th anniversary of Tianjin University","authors":"Wenping Hu,&nbsp;Wenbin Hu,&nbsp;Quanhong Yang","doi":"10.1007/s40843-025-3659-6","DOIUrl":"10.1007/s40843-025-3659-6","url":null,"abstract":"","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"2997 - 2998"},"PeriodicalIF":7.4,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asymmetric catalysis promoted by hierarchical chirality of metal nanoclusters","authors":"Fang Fang \u0000 (,&nbsp;),&nbsp;Moshuqi Zhu \u0000 (,&nbsp;),&nbsp;Qiaofeng Yao \u0000 (,&nbsp;),&nbsp;Wenping Hu \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3569-7","DOIUrl":"10.1007/s40843-025-3569-7","url":null,"abstract":"<div><p>Asymmetric catalytic reactions, in which diverse enantioselective catalysts have been developed for maximizing turnover number and enantiomeric excess, serve as the cornerstone strategy for achieving molecular stereoselectivity in fine chemicals and pharmaceutical industry. In recent years, chiral metal nanoclusters (NCs) have emerged as a cutting-edge research frontier in asymmetric catalysis due to their precisely tunable structural attributes at the unprecedented atomic level, as well as their hierarchical structures reminiscent of natural proteins. It has become known that chirality can emerge at diverse structural hierarchies, including metal core, metal-ligand interface, ligand body, and assembly patterns of metal NCs, offering an ideal platform to not only boost the catalytic activity but also understand the catalytic mechanism in asymmetric reactions. This review systematically summarizes recent progress in the synthesis and asymmetric catalytic applications of chiral metal NCs, based on their core-shell structure scheme. The discussion starts with a brief elaboration on the structural origin of cluster chirality, followed by a concise account of the synthetic methodologies delivering enantiopure metal NCs. Before concluding this review with our perspectives on metal NCs-based asymmetric catalysis, the catalytic applications of chiral metal NCs are outlined. The fundamental and applicable advances summarized in this review should be useful for designing chiral metal NCs for asymmetric catalytic applications.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3075 - 3092"},"PeriodicalIF":7.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrogen-bond-mediated supramolecular polyhedra","authors":"Ran-Qi Chen \u0000 (,&nbsp;),&nbsp;Feiyue Liu \u0000 (,&nbsp;),&nbsp;Yujie Xing \u0000 (,&nbsp;),&nbsp;Jiayi Wang \u0000 (,&nbsp;),&nbsp;Aspen X.-Y. Chen \u0000 (,&nbsp;),&nbsp;Yu Wang \u0000 (,&nbsp;),&nbsp;Huang Wu \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3568-4","DOIUrl":"10.1007/s40843-025-3568-4","url":null,"abstract":"<div><p>Many viral capsids with spherical structures represent the most exemplary polyhedral architectures in nature, with icosahedral symmetry being particularly prototypical. These polyhedral capsids are formed through the spontaneous self-assembly of multiple identical protein subunits via non-covalent interactions following precisely symmetry-matching rules. Inspired by this biological self-assembly mechanism, the construction of biomimetic polyhedra has emerged as a prominent research focus in supramolecular chemistry. Notwithstanding the significant challenges in structural stability and geometric precision control faced by hydrogen bond-directed polyhedral assembly systems, these supramolecular constructs exhibit extraordinary promise in synthetic chemistry and materials science, owing to their distinctive dynamic responsiveness, reversible assembly behavior, and versatile structural designability. This review methodically categorizes the structural types of hydrogen-bonded supramolecular polyhedra and their building block characteristics, explores key scientific challenges in the field, and further outlines future research trends. The work hopes to establish a theoretical framework and methodological guidance for the controlled assembly and functionalization of bioinspired hydrogen-bonded polyhedral structures, thereby advancing supramolecular materials toward precision and intelligent development.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3093 - 3113"},"PeriodicalIF":7.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Composite protective coating on lithium metal anodes for polysulfide shielding in lithium-sulfur batteries","authors":"Lixue Yang \u0000 (,&nbsp;),&nbsp;Zhiyuan Han \u0000 (,&nbsp;),&nbsp;Chen Zhang \u0000 (,&nbsp;),&nbsp;Yun Cao \u0000 (,&nbsp;),&nbsp;Wei Lv \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3601-6","DOIUrl":"10.1007/s40843-025-3601-6","url":null,"abstract":"<div><p>Lithium-sulfur (Li-S) batteries face significant challenges due to the environmental sensitivity, dendrite growth and polysulfide-induced side reactions of lithium metal anodes (LMAs), which compromise their safety and cycle life. To address these issues, we develop a composite protective layer comprising layer-by-layer assembled graphene oxide (GO) films coated with 1H,1H,2H,2H-perfluorodecyl trichlorosilane (FDTS). The lithium-reduced GO framework establishes uniform ion-conducting channels that homogenize Li-ion flux, enabling uniform deposition and suppressing dendrite formation. At the same time, the hydrophobic organic coating serves as a robust barrier against water, air and lithium polysulfides (LiPSs), enabling the environmental and electrochemical stability of LMAs. As a result, the protected LMAs maintain exceptional stability upon direct contact with water and exposure in humid air (relative humidity 35%). When integrated into Li-S batteries with high sulfur loadings (4.5 mg cm⁻²), the protected LMAs enable a capacity retention of 61.1% over 300 cycles, showing improved cycling performance. This work provides a scalable approach to stabilizing LMAs for practical Li-S batteries.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3295 - 3303"},"PeriodicalIF":7.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Purely zwitterionic polymer injectable hydrogels for vitreous substitutes","authors":"Liping Lang \u0000 (,&nbsp;),&nbsp;Huijie Hao \u0000 (,&nbsp;),&nbsp;Jia Yao \u0000 (,&nbsp;),&nbsp;Haolun Wang \u0000 (,&nbsp;),&nbsp;Hongying Wang \u0000 (,&nbsp;),&nbsp;Man Liu \u0000 (,&nbsp;),&nbsp;Xiaoli Xing \u0000 (,&nbsp;),&nbsp;Jianhai Yang \u0000 (,&nbsp;),&nbsp;Wenguang Liu \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3620-x","DOIUrl":"10.1007/s40843-025-3620-x","url":null,"abstract":"<div><p>Current clinical vitreous substitutes employed in vitrectomy and retinal surgery are frequently associated with complications such as emulsification, vitreous opacities, and inflammation, highlighting the urgent demand for safer biomaterial alternatives. Herein, we report a purely zwitterionic polymer hydrogel for vitreous replacement, which is constructed entirely from a zwitterionic monomer (carboxybetaine ureido acrylate) without any covalent cross-linkers or non-zwitterionic segments, and self-crosslinked via multi-valent hydrogen bonding and dipole-dipole interactions. The supramolecular network of poly(carboxybetaine ureido acrylate) (PCBUIA) hydrogels exhibits pronounced shear-thinning properties for smooth injection and rapid self-healing to restore mechanical integrity once the shear force is removed. The PCBUIA hydrogels also match native vitreous in density (1.016–1.021 g/cm³), refractive index (1.3359–1.3389) and transmittance (&gt; 90%), while exhibiting comparable viscoelastic behavior. Moreover, the zwitterionic hydration layer confers PCBUIA hydrogels with ultralow protein adsorption and markedly suppresses cell attachment; notably, it cannot provoke any foreign-body reaction or fibrotic capsule formation, demonstrating an outstanding biocompatibility. After one month of implantation in rabbit eyes, the PCBUIA hydrogels maintained optical transparency, preserved native retinal morphology, and did not cause elevated intraocular pressure and inflammatory response. These findings demonstrate the potential of purely zwitterionic polymer hydrogels as vitreous substitutes. However, further long-term <i>in vivo</i> studies are required to evaluate their stability and functional performance.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3390 - 3400"},"PeriodicalIF":7.4,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Star-shaped cross-linkable hole transport materials with high triplet energy and deep HOMO energy enable efficient solution-processed deep-blue TADF OLEDs","authors":"Jiaxu Bai \u0000 (,&nbsp;),&nbsp;Jingyuan Feng \u0000 (,&nbsp;),&nbsp;Chuanxin Liao \u0000 (,&nbsp;),&nbsp;Tianhao Wang \u0000 (,&nbsp;),&nbsp;Shirong Wang \u0000 (,&nbsp;),&nbsp;Hongli Liu \u0000 (,&nbsp;),&nbsp;Xianggao Li \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3638-2","DOIUrl":"10.1007/s40843-025-3638-2","url":null,"abstract":"<div><p>Cross-linkable hole transport materials (x-HTMs) play a crucial role in solving the issue of interlayer mixing of solution-processed organic light-emitting diodes (OLEDs). However, issues such as energy level mismatch and low hole mobility hinder the application of x-HTMs in deep-blue OLEDs. In particular, thermally activated delayed fluorescent (TADF) emitters require HTMs with high triplet energies (<i>E</i>_T) to ensure high exciton utilization efficiency. Here, two star-shaped cross-linkable HTMs 5-(9<i>H</i>-carbazol-9-yl)-<i>N</i>¹,<i>N</i>³-di(<i>p</i>-tolyl)-<i>N</i>¹,<i>N</i>³-bis(4-vinylphenyl)benzene-1,3-diamine (m-V-CzDPA) and <i>N</i>¹,<i>N</i>¹-diphenyl-<i>N</i>³,<i>N</i>⁵-di(<i>p</i>-tolyl)-<i>N</i>³,<i>N</i>⁵-bis(4-vinylphenyl) benzene-1,3,5-triamine (m-V-DPADPA) were designed and synthesized. Owing to their aromatic torsion structures, m-V-CzDPA and m-V-DPADPA possessed high <i>E</i>_Ts of 2.89 and 2.87 eV, respectively, which can effectively confine triplet excitons in the emitting layer (EML). The carrier diffusion coefficients of their x-HTMs, x-m-CzDPA and x-m-DPADPA, which were obtained via carrier diffusion imaging characterization were 0.54 and 0.44 cm² s⁻¹, respectively, thus indicating outstanding intrinsic hole transport capacity, with hole mobilities of 4.30×10⁻⁴ and 1.39×10⁻⁴ cm² V⁻¹ s⁻¹, respectively. Solution-processed deep-blue TADF-OLEDs employing x-m-CzDPA as the HTM achieved a maximum current efficiency/maximum external quantum efficiency of 5.25 cd A⁻¹/18.06%, with CIE coordinates of (0.162, 0.042). This is the first time that x-HTMs have served as efficient deep-blue TADF-OLEDs via a solution process, which also meets the latest BT. 2020 standard (CIE_<i>y</i> ⩽ 0.046).</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3239 - 3249"},"PeriodicalIF":7.4,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stretchable and low-voltage electrolyte gate organic thin film transistors based on ionic gel for glucose sensing","authors":"Hongchen Jiang \u0000 (,&nbsp;),&nbsp;Xiaoying Zhang \u0000 (,&nbsp;),&nbsp;Xiangxiang Li \u0000 (,&nbsp;),&nbsp;Yan Wang \u0000 (,&nbsp;),&nbsp;Weiyu Wang \u0000 (,&nbsp;),&nbsp;Xin Ye \u0000 (,&nbsp;),&nbsp;Hui Yang \u0000 (,&nbsp;),&nbsp;Wenping Hu \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3632-9","DOIUrl":"10.1007/s40843-025-3632-9","url":null,"abstract":"<div><p>Stretchable extended-gate organic thin film transistor (OTFT) not only retains the high selectivity inherent to electrochemical sensing but also integrates the intrinsic flexibility and <i>in situ</i> signal amplification capabilities of stretchable organic thin film transistors. This design significantly reduces the signal processing burden at the backend, enhances signal sensitivity, and extends the detection limit, demonstrating great potential for wearable sweat sensors. However, the widespread adoption of stretchable OTFT in wearable electronics has been hindered by their high operating voltages and limited operational stability. Here, a stretchable ionic gel was proposed as the dielectric layer, enabling the fabrication of intrinsically stretchable electrolyte gate organic thin film transistor (EGOTFT) with ultralow operating voltages (&lt;1 V). The resulting devices exhibited a remarkably low operating voltage of −0.5 V, excellent long-term stability (over 30 days), and a steep subthreshold slope of 98 mV dec⁻¹. Meanwhile, the stretchable EGOTFT demonstrated high mechanical durability, maintaining stable electrical performance under 40% strain and after 10⁴ stretching-releasing cycles. Based on this EGOTFT architecture, a wearable glucose sensor was realized, meeting the safety and conformability requirements for wearable biomedical applications. This work opens a new opportunity for e-skin with signal-identification capabilities.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3368 - 3376"},"PeriodicalIF":7.4,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A dual-dynamically crosslinked hydrogel for cardiac repair with microenvironment regulation and angiogenic functions","authors":"Haitao Zhang \u0000 (,&nbsp;),&nbsp;Lei Liang \u0000 (,&nbsp;),&nbsp;Zhiwei Yue \u0000 (,&nbsp;),&nbsp;Chengyao Wang \u0000 (,&nbsp;),&nbsp;Linyu Chen \u0000 (,&nbsp;),&nbsp;Jiajun Lu \u0000 (,&nbsp;),&nbsp;Hong Zhang \u0000 (,&nbsp;),&nbsp;Fanglian Yao \u0000 (,&nbsp;),&nbsp;Hong Sun \u0000 (,&nbsp;),&nbsp;Junjie Li \u0000 (,&nbsp;)","doi":"10.1007/s40843-025-3619-1","DOIUrl":"10.1007/s40843-025-3619-1","url":null,"abstract":"<div><p>Inflammation and ischemic microenvironments represent significant challenges in cardiac repair. To address these issues, we developed a series of dual-dynamically crosslinked alginate-based hydrogels (SA-PBA/E/Sr) containing strontium ions (Sr²⁺) and epigallocatechin gallate (EGCG), which demonstrate microenvironment modulation and angiogenic capabilities in the myocardial infarction (MI) microenvironment. In the SA-PBA/E/Sr hydrogel system, alginate modified with aminophenylboronic acid (PBA) was synthesized to form boronic acid ester bonds with EGCG and an ionic coordination network with Sr²⁺ ions. The resulting hydrogel exhibits excellent injectability due to its dual-dynamically crosslinked structure, with its formation and mechanical properties being tunable modulated by the PBA substitution degree, EGCG concentration, and Sr²⁺ content. The incorporation of EGCG enables the hydrogel to efficiently scavenge reactive oxygen species (ROS) and mitigate oxidative stress-induced cellular damage under hypoxia. Furthermore, the introduction of Sr²⁺ significantly enhances the migratory capacity of endothelial cells, a critical factor in angiogenesis. <i>In vivo</i> experiments revealed that the injection of SA-PBA/E/Sr hydrogel into the infarcted myocardium of Sprague-Dawley (SD) rats led to reduced ROS levels, alleviated inflammatory responses, suppression of pro-inflammatory M1 macrophage expression, enhancement of anti-inflammatory M2 macrophage expression, and accelerated neovascularization in the damaged tissue. Echocardiographic and histological analyses demonstrated a remarkable increase in ejection fraction and a decreased infarct size, collectively indicating significant cardiac functional recovery.</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":773,"journal":{"name":"Science China Materials","volume":"68 9","pages":"3377 - 3389"},"PeriodicalIF":7.4,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}