American Journal of Otolaryngology最新文献_第5页

Rethinking indications for prophylactic central neck dissection in papillary thyroid microcarcinoma: A real-world retrospective study 重新思考乳头状甲状腺微癌预防性中央颈部清扫术的适应症：一项真实世界的回顾性研究。

IF 1.8 4区医学

American Journal of Otolaryngology Pub Date : 2026-07-01 DOI: 10.1016/j.amjoto.2026.104884

Lei Gong, Ping Li, Ziyang Zhang, Mengying Cao, Yan Liu, Jun Chen, Xinghong Guo, Weili Liang, Nan Liu, Bin Lv, Kai Liang

{"title":"Rethinking indications for prophylactic central neck dissection in papillary thyroid microcarcinoma: A real-world retrospective study","authors":"Lei Gong, Ping Li, Ziyang Zhang, Mengying Cao, Yan Liu, Jun Chen, Xinghong Guo, Weili Liang, Nan Liu, Bin Lv, Kai Liang","doi":"10.1016/j.amjoto.2026.104884","DOIUrl":"10.1016/j.amjoto.2026.104884","url":null,"abstract":"<div><h3>Background</h3><div>The treatment of unifocal papillary thyroid microcarcinoma (PTMC) remains controversial. The study analyzed preoperative clinical characteristics and postoperative pathologic features of unifocal PTMC to provide new insights into whether prophylactic central neck dissection (pCND) should be performed in PTMC.</div></div><div><h3>Methods</h3><div>A total of 1475 patients with clinical lymph node-negative (cN0) unifocal PTMC who underwent thyroid lobectomy and pCND were retrospectively analyzed. Univariate and multivariate logistic regression analyses were performed to determine independent risk factors of central lymph node metastasis (CLNM). The decision tree model was used to identify the risk for CLNM in PTMC patients and indications for pCND.</div></div><div><h3>Results</h3><div>Age, gender, tumor size and location were risk factors for CLNM in cN0 unifocal PTMC patients. The root node of the decision tree model revealed location was the main factor affecting CLNM, and the potential risk of CLNM was the lowest in the intraglandular lesion regardless of gender, age, and tumor size. If lesions located in subcapsular/isthmus lesion, the potential risk was higher and was associated with age, gender, and tumor size.</div></div><div><h3>Conclusion</h3><div>For patients with cN0 unifocal PTMC, regardless of gender, age, or tumor size, the risk of CLNM is the lowest when the lesion is located within the gland. In contrast, the potential risk of CLNM is higher when the lesion is subcapsular or located in the isthmus. In such cases, the decision to perform pCND should be made by integrating the patient's gender, age, and tumor size.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"47 4","pages":"Article 104884"},"PeriodicalIF":1.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148387082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prophylactic endoluminal vacuum therapy after total laryngectomy or laryngopharyngectomy: a retrospective propensity score-matched cohort study 全喉切除术或喉咽切除术后预防性腔内真空治疗：回顾性倾向评分匹配队列研究。

IF 1.8 4区医学

American Journal of Otolaryngology Pub Date : 2026-07-01 Epub Date: 2026-07-04 DOI: 10.1016/j.amjoto.2026.104889

Eun Kyung Jung, Juwon Hwang, Hyunjun Jung, Hye-Bin Jang, Joon Kyoo Lee

{"title":"Prophylactic endoluminal vacuum therapy after total laryngectomy or laryngopharyngectomy: a retrospective propensity score-matched cohort study","authors":"Eun Kyung Jung, Juwon Hwang, Hyunjun Jung, Hye-Bin Jang, Joon Kyoo Lee","doi":"10.1016/j.amjoto.2026.104889","DOIUrl":"10.1016/j.amjoto.2026.104889","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the impact of prophylactic endoluminal vacuum-assisted closure (EndoVAC) on pharyngocutaneous fistula (PCF) incidence and duration of hospitalization following total laryngectomy (TL) or laryngopharyngectomy (LP).</div></div><div><h3>Methods</h3><div>This retrospective cohort study included patients who underwent TL or LP at a single tertiary center between May 2006 and August 2025. PCF was defined based on clinical evidence of salivary leakage and/or radiologic confirmation using contrast-enhanced computed tomography or pharyngoesophagography. Multivariable logistic regression and 1:1 nearest-neighbor propensity score matching (PSM) were performed using age, defect size, flap type, and preoperative radiotherapy as covariates. Duration of hospitalization was analyzed using multivariable linear regression.</div></div><div><h3>Results</h3><div>Among 114 patients, PCF occurred in 38 patients (33.3%). Prophylactic EndoVAC use was not significantly associated with PCF incidence in multivariable analysis (adjusted OR, 0.50, 95% CI, 0.12–2.05; <em>p</em> = 0.336). In the propensity score-matched cohort (<em>n</em> = 34), PCF occurred in 47.1% of the EndoVAC group and 29.4% of controls (OR, 2.13, 95% CI, 0.52–8.76; <em>p</em> = 0.481). However, prophylactic EndoVAC use was independently associated with a significantly shorter duration of hospitalization (β = −25.8 days, 95% CI, −41.7 to −9.9; <em>p</em> = 0.002).</div></div><div><h3>Conclusion</h3><div>Prophylactic EndoVAC was not associated with reduced PCF incidence after TL or LP. Although EndoVAC use was associated with shorter hospitalization, this finding should be considered exploratory and hypothesis-generating because of potential residual confounding and selection bias.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"47 4","pages":"Article 104889"},"PeriodicalIF":1.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148417637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Socially awkward: An evaluation of otolaryngology residency pre- or post-interview social functions 社交尴尬：对耳鼻喉科住院医师面试前后社交功能的评估。

IF 1.8 4区医学

American Journal of Otolaryngology Pub Date : 2026-07-01 Epub Date: 2026-06-25 DOI: 10.1016/j.amjoto.2026.104872

Brandon D. Abell, Phillip Q. Richards, Ryan J. Lau, Cristina Cabrera-Muffly, Andrew P. Johnson

{"title":"Socially awkward: An evaluation of otolaryngology residency pre- or post-interview social functions","authors":"Brandon D. Abell, Phillip Q. Richards, Ryan J. Lau, Cristina Cabrera-Muffly, Andrew P. Johnson","doi":"10.1016/j.amjoto.2026.104872","DOIUrl":"10.1016/j.amjoto.2026.104872","url":null,"abstract":"<div><h3>Objective</h3><div>As otolaryngology residency programs transition to in-person or hybrid interview and social activities following the COVID-19 pandemic, applicant opinions on what makes the most appealing and informative recruitment social events must be considered. The objective of this study was to determine which components of pre- or post-interview socials are most important to otolaryngology residency applicants.</div></div><div><h3>Design</h3><div>The survey was distributed to 347 applicants to the University of Colorado otolaryngology residency program during the 2024 Match, of which 65 responses were received. Survey responses were collected through an anonymous web-based survey and used to calculate descriptive statistics.</div></div><div><h3>Results</h3><div>In-person social events were unanimously preferred (100%), with rationale including interactions with residents and other applicants, and having a chance to see the city (“liked” by >98.4%). Respondents were split on having attending physicians present (49% in-favor), but 71.4% of respondents preferred in-person social events because they liked interactions with attending physicians. Less important factors for preferring in-person social events included the dining experiences and opportunities to ask questions in a less-formal environment.</div></div><div><h3>Conclusions</h3><div>Although virtual events are flexible and inexpensive, most respondents preferred in-person social events and interviews for their ability to experience the culture and interpersonal working relationships within a department. While virtual social events can provide some information about a program, they have limited utility in conveying the culture and fit of a program and do not facilitate organic conversation. These survey responses provide insight into the ways that otolaryngology residency programs can create the most useful pre- or post-interview social events.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"47 4","pages":"Article 104872"},"PeriodicalIF":1.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148343812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid improvement of nasal obstruction after treatment with a non-vasoconstrictive osmotic nasal spray: A prospective observational study 非血管收缩性渗透性鼻喷雾剂治疗后鼻塞的快速改善：一项前瞻性观察研究。

IF 1.8 4区医学

American Journal of Otolaryngology Pub Date : 2026-07-01 Epub Date: 2026-06-27 DOI: 10.1016/j.amjoto.2026.104877

Pietro De Luca, Arianna Di Stadio, Luca de Campora, Anna Sambito, Valerio Damiani, Angelo Camaioni, Matteo Simone

{"title":"Rapid improvement of nasal obstruction after treatment with a non-vasoconstrictive osmotic nasal spray: A prospective observational study","authors":"Pietro De Luca, Arianna Di Stadio, Luca de Campora, Anna Sambito, Valerio Damiani, Angelo Camaioni, Matteo Simone","doi":"10.1016/j.amjoto.2026.104877","DOIUrl":"10.1016/j.amjoto.2026.104877","url":null,"abstract":"<div><h3>Background</h3><div>Nasal obstruction is a highly prevalent symptom that can significantly impair quality of life. Although topical decongestants provide rapid relief, their use is limited by potential adverse effects. Non-vasoconstrictive treatments represent a safer alternative, but data on their immediate effectiveness in clinical practice are limited.</div></div><div><h3>Objective</h3><div>To evaluate the short-term effects of a non-vasoconstrictive osmotic nasal spray on subjective symptoms and objective nasal airflow parameters in patients with nasal obstruction.</div></div><div><h3>Methods</h3><div>This prospective observational study included 83 adult patients presenting with nasal obstruction. Subjective symptoms were assessed using the Visual Analog Scale (VAS) and the I-NOSE questionnaire. Objective nasal patency was measured by active anterior rhinomanometry. Assessments were performed at baseline (T0) and 10 min after treatment (T1).</div></div><div><h3>Results</h3><div>Significant improvements were observed in all outcome measures. The mean VAS score decreased from 8.8 to 4.8 (mean difference − 4.0; 95% CI: −4.4 to −3.6; <em>p</em> < 0.0001). The I-NOSE score decreased from 18.4 to 10.3 (mean difference − 8.1; 95% CI: −9.0 to −7.2; <em>p</em> < 0.0001). Total nasal airway resistance decreased from 0.70 to 0.37 Pa/cm<sup>3</sup>/s (mean difference − 0.33; 95% CI: −0.39 to −0.27; p < 0.0001). No adverse events were reported.</div></div><div><h3>Conclusions</h3><div>A single administration of a non-vasoconstrictive osmotic nasal spray produced rapid improvement in both subjective perception of nasal obstruction and objective airflow measurements. These findings suggest that osmotic therapy may represent a useful option for short-term relief of nasal obstruction.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"47 4","pages":"Article 104877"},"PeriodicalIF":1.8,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148366632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The intriguing condition of eosinophilic sialodochitis: insights into an emerging type 2 disorder 嗜酸性粒细胞性涎腺炎的耐人寻味的条件：洞察新出现的2型疾病。

IF 1.7 4区医学

American Journal of Otolaryngology Pub Date : 2026-05-01 Epub Date: 2026-03-19 DOI: 10.1016/j.amjoto.2026.104810

Matteo Lazzeroni , Eugenio De Corso , Andrea De Lena , Cristina Amaglio , Emanuele Bizzi , Giulia Gramellini , Niccolò Cenzato , Michele Gaffuri , Antonino Maniaci , Pasquale Capaccio

{"title":"The intriguing condition of eosinophilic sialodochitis: insights into an emerging type 2 disorder","authors":"Matteo Lazzeroni , Eugenio De Corso , Andrea De Lena , Cristina Amaglio , Emanuele Bizzi , Giulia Gramellini , Niccolò Cenzato , Michele Gaffuri , Antonino Maniaci , Pasquale Capaccio","doi":"10.1016/j.amjoto.2026.104810","DOIUrl":"10.1016/j.amjoto.2026.104810","url":null,"abstract":"<div><h3>Background</h3><div>Eosinophilic sialodochitis is a rare and increasingly recognized inflammatory disorder of the salivary glands, characterized by eosinophil-rich mucus plugs, periductal eosinophilic infiltration, and frequent association with type 2 disorders.</div></div><div><h3>Methods</h3><div>A systematic search was conducted on PubMed, Embase, Scopus, and Web of Science for papers reporting on eosinophilic sialodochitis. PRISMA 2020 guidelines were followed, and the study protocol was registered in PROSPERO with registration number CRD42023433994. Data was summarized descriptively and presented as percentages or medians with interquartile range.</div></div><div><h3>Results</h3><div>A total of 157 studies were identified and 21 met the inclusion criteria of the present review, comprising 179 patients. The majority were female (73%) and their ages ranged from 15 to 80 years old. Eosinophilic sialodochitis often presented with multiglandular involvement of the parotid glands. Allergic rhinitis (72%) and asthma (28%) were the most common associated type 2 comorbidities, while elevated serum IgE and blood eosinophil count were frequently reported. Diagnosis was based on different examinations, ranging from ultrasonography to MRI, fine-needle or core-needle biopsy, and conventional sialography. Therapeutic interventions included antihistamines, montelukast, and oral corticosteroids. Sialendoscopy and sialadenectomy were used in refractory cases, while biologics such as dupilumab, benralizumab and mepolizumab were employed only in 4 patients.</div></div><div><h3>Conclusions</h3><div>This review highlights the diagnostic complexity, therapeutic challenges, and potential role of targeted biologic therapies in managing eosinophilic sialodochitis.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"47 3","pages":"Article 104810"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147832343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic utility of tubomanometry for patulous eustachian tube: A comparative study 咽鼓管扩张性诊断的比较研究。

IF 1.7 4区医学

American Journal of Otolaryngology Pub Date : 2026-05-01 Epub Date: 2026-04-22 DOI: 10.1016/j.amjoto.2026.104846

Xiaoling Shi , Ren Zhou , Yanbo Yin , Yunfeng Wang

{"title":"Diagnostic utility of tubomanometry for patulous eustachian tube: A comparative study","authors":"Xiaoling Shi , Ren Zhou , Yanbo Yin , Yunfeng Wang","doi":"10.1016/j.amjoto.2026.104846","DOIUrl":"10.1016/j.amjoto.2026.104846","url":null,"abstract":"<div><h3>Purpose</h3><div>The current diagnosis of patulous Eustachian tube (PET) has limitations and cannot accurately assess its functional status. This study aims to validate tubomanometry (TMM) as an objective diagnostic tool for PET by analyzing pressure-specific R-values.</div></div><div><h3>Methods</h3><div>A retrospective cohort study was conducted involving 95 ears from 64 patients which were stratified into three groups: Definite PET (<em>n</em> = 26), Possible PET (<em>n</em> = 41), and Controls (<em>n</em> = 28). Diagnostic performance was evaluated by receiver operator characteristic (ROC) curve analysis to determine optimal R-value thresholds.</div></div><div><h3>Results</h3><div>The Definite PET group exhibited significantly lower R-values compared to the Possible PET and Control groups at all pressure levels (30 mbar: 0.27 ± 0.39 <em>vs</em> 0.40 ± 0.34 <em>vs</em> 0.99 ± 0.49, <em>p</em> < 0.001; 40 mbar: 0.39 ± 0.55 <em>vs</em> 0.54 ± 0.44 <em>vs</em> 0.75 ± 0.31, <em>p</em> = 0.001; 50 mbar: 0.32 ± 0.33 <em>vs</em> 0.41 ± 0.33 <em>vs</em> 0.70 ± 0.32, <em>p</em> < 0.001). The optimal diagnostic threshold was achieved at 30 mbar (R-value cutoff: 0.585; sensitivity: 75%, specificity: 77%, area under curve [AUC]: 0.802). Asymptomatic contralateral ears in unilateral PET cases exhibited R-values that were similar to healthy controls (<em>p</em> > 0.05).</div></div><div><h3>Conclusion</h3><div>TMM is a robust diagnostic tool for PET, with optimal clinical utility at 30 mbar. Pressure-specific R-value thresholds can differentiate the severity of PET and validate the status of asymptomatic ears in unilateral cases.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"47 3","pages":"Article 104846"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postoperative recurrent laryngeal nerve paralysis in thyroid carcinoma surgery 甲状腺癌手术后喉返神经麻痹。

IF 1.7 4区医学

American Journal of Otolaryngology Pub Date : 2026-05-01 Epub Date: 2026-04-24 DOI: 10.1016/j.amjoto.2026.104849

Takemasa Terao, Ryota Kiwaki, Yorihisa Orita

{"title":"Postoperative recurrent laryngeal nerve paralysis in thyroid carcinoma surgery","authors":"Takemasa Terao, Ryota Kiwaki, Yorihisa Orita","doi":"10.1016/j.amjoto.2026.104849","DOIUrl":"10.1016/j.amjoto.2026.104849","url":null,"abstract":"<div><h3>Objective</h3><div>Recurrent laryngeal nerve (RLN) paralysis is a significant complication of thyroid surgery. Even with meticulous nerve preservation, postoperative RLN paralysis can still occur. We investigate risk factors for postoperative RLN paralysis among the patients with thyroid carcinoma.</div></div><div><h3>Methods</h3><div>Between 2017 and 2023, 216 patients underwent surgery for thyroid carcinoma at Kumamoto University Hospital. Among these, 26 patients displayed preoperative vocal cord paralysis. Records for the remaining 190 patients were reviewed retrospectively to identify risk factors for postoperative RLN paralysis.</div></div><div><h3>Results</h3><div>Among the 190 cases, 16 required RLN resection during surgery due to tumor invasion. Out of the remaining 174 patients who preserved RLN, 29 suffered temporary and 7 permanent postoperative RLN paralysis. Tracheal invasion was identified as a significant risk factor for the need to resect RLN during surgery, even in the absence of preoperative RLN paralysis (OR 7.0, <em>P</em> = 0.038). For patients suffering postoperative RLN paralysis even though preserving RLN during surgery, RLN shaving (OR 42.8, <em>P</em> < 0.001) and blood loss (OR 1.51 per 100 mL increase, <em>p</em> = 0.024) were identified as an independent factor. Excluding RLN shaving cases, blood loss was an independent factor.</div></div><div><h3>Conclusion</h3><div>Patients with suspected tracheal invasion preoperatively are at high risk of requiring intraoperative RLN resection. Among the patients with thyroid carcinoma who preserved RLN during surgery, the cases in which nerve preservation was achieved by shaving technique and those with greater intraoperative bleeding had a higher risk of postoperative RLN paralysis.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"47 3","pages":"Article 104849"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperbaric oxygen combined with postauricular and intratympanic steroid injections in diabetic patients with severe or profound refractory sudden sensorineural hearing loss 高压氧联合耳后和鼓室内类固醇注射治疗糖尿病合并重度或重度难治性突发性感音神经性听力损失

IF 1.7 4区医学

American Journal of Otolaryngology Pub Date : 2026-05-01 Epub Date: 2026-04-22 DOI: 10.1016/j.amjoto.2026.104838

Huimei Li, Chenyang Zhao, Weihong Zhang, Yin Fu

{"title":"Hyperbaric oxygen combined with postauricular and intratympanic steroid injections in diabetic patients with severe or profound refractory sudden sensorineural hearing loss","authors":"Huimei Li, Chenyang Zhao, Weihong Zhang, Yin Fu","doi":"10.1016/j.amjoto.2026.104838","DOIUrl":"10.1016/j.amjoto.2026.104838","url":null,"abstract":"<div><h3>Background</h3><div>Patients with type 2 diabetes mellitus (T2DM) and severe or profound refractory sudden sensorineural hearing loss (RSSNHL) urgently require more effective salvage therapies.</div></div><div><h3>Aim</h3><div>This study aimed to evaluate the efficacy of a triple salvage therapy—combining hyperbaric oxygen (HBO), intratympanic steroids (ITS), and postauricular steroid injections (PSI)—for severe or profound RSSNHL in diabetic patients.</div></div><div><h3>Methods</h3><div>This retrospective study analyzed 117 patients with unilateral severe or profound RSSNHL and concurrent T2DM between January 2020 and December 2024. All patients underwent salvage therapy with PSI and ITS, either with (<em>n</em> = 60) or without (<em>n</em> = 57) HBO. The primary efficacy endpoint was the change in hearing level, while secondary endpoints included changes in glycemic control, tinnitus and vertigo symptoms, anxiety and depression scores, and sleep quality.</div></div><div><h3>Results</h3><div>Compared to the No-HBO group, the HBO group achieved superior post-salvage efficacy, with significantly higher cure rates, clinical effectiveness rates, and hearing threshold gain (<em>P</em> < 0.05), while maintaining a comparable safety profile (<em>P</em> > 0.05). Salvage therapy improved glycemic control, neurotological symptoms, sleep, and psychological status in both groups, with greater benefits observed in the HBO group (<em>P</em> < 0.05). Shorter intervals from symptom onset to salvage therapy and shorter T2DM duration were associated with significantly greater hearing improvement (<em>P</em> < 0.05).</div></div><div><h3>Conclusion</h3><div>This triple salvage therapy effectively treats severe or profound RSSNHL in diabetic patients, improving auditory outcomes, glycemic control, and comorbid symptoms without increasing the incidence of adverse events.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"47 3","pages":"Article 104838"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

“Critical methodological considerations in the study of combined tDCS and counseling for chronic tinnitus” 慢性耳鸣联合tDCS和咨询研究的关键方法学考虑

IF 1.7 4区医学

American Journal of Otolaryngology Pub Date : 2026-05-01 Epub Date: 2026-01-03 DOI: 10.1016/j.amjoto.2025.104785

Ho Yun Lee

引用次数: 0

Self-perception of balance function in adults following cochlear implant surgery: A cross-sectional study 成人人工耳蜗术后平衡功能的自我感知：一项横断面研究

IF 1.7 4区医学

American Journal of Otolaryngology Pub Date : 2026-05-01 Epub Date: 2026-04-25 DOI: 10.1016/j.amjoto.2026.104843

Rania Alkahtani , Abeer Alotaibi , Arwa Alhussain , Layan Algharbi , Reenad Al-hlail , Reem Elbeltagy , Hadeel Alsaleh , Sahar Asqool

{"title":"Self-perception of balance function in adults following cochlear implant surgery: A cross-sectional study","authors":"Rania Alkahtani , Abeer Alotaibi , Arwa Alhussain , Layan Algharbi , Reenad Al-hlail , Reem Elbeltagy , Hadeel Alsaleh , Sahar Asqool","doi":"10.1016/j.amjoto.2026.104843","DOIUrl":"10.1016/j.amjoto.2026.104843","url":null,"abstract":"<div><h3>Objective</h3><div>To assess self-perceived balance function in adults after cochlear implantation and explore factors associated with postoperative vertigo.</div></div><div><h3>Methods</h3><div>A cross-sectional questionnaire-based study was conducted among adult cochlear implant recipients (≥18 years). Collected data included demographics, hearing history, vestibular symptoms before and after implantation, and satisfaction with hearing outcomes. Chi-square analysis was used to examine associations between vertigo and clinical variables.</div></div><div><h3>Results</h3><div>A total of 50 adult participants were included. Perception of vertigo was reported by 38% prior to implantation and 48% post-implantation. Among those with post-implant symptoms, 58.3% experienced vertigo daily, and 54.2% rated their symptoms as moderate in severity. The majority of symptoms developed within one month post-surgery. Male sex was significantly associated with a higher incidence of post-implant vertigo (<em>p</em> = 0.049), while no significant associations were observed with other factors.</div></div><div><h3>Conclusion</h3><div>Nearly half of adult cochlear implant recipients reported postoperative vertigo, with many describing symptoms of moderate severity that interfered with daily activities. These findings underscore the importance of incorporating systematic pre- and post-operative vestibular assessment and follow-up into standard cochlear implant care.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"47 3","pages":"Article 104843"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147803288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0