American Journal of Otolaryngology最新文献

{"title":"Incidence and characteristics of sudden sensorineural hearing loss during pregnancy and the postpartum period: A nationwide population-based study using customized cohort data","authors":"Taeung Eom ,&nbsp;Byungjun Jeong ,&nbsp;Seok-Hyun Kim ,&nbsp;Dong-Jo Kim ,&nbsp;Il-Woo Lee ,&nbsp;Hyun Min Lee ,&nbsp;Hwi Gon Kim","doi":"10.1016/j.amjoto.2025.104600","DOIUrl":"10.1016/j.amjoto.2025.104600","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to investigate the incidence and characteristics of sudden sensorineural hearing loss (SSNHL) in pregnant and non-pregnant women using the Korean National Health Insurance Service customized cohort data.</div></div><div><h3>Materials and methods</h3><div>We defined the delivery group as women aged 15–49 years with International Classification of Diseases 10th Revision codes O80-O84 indicating delivery between January 2013 and December 2019. The control group was selected from individuals in the same age range without a history of delivery during the same period. SSNHL was defined as having an H91.2 diagnostic code and having undergone audiometry at least once. The incidence and characteristics of SSNHL were compared between the two groups from 2015 to 2018.</div></div><div><h3>Results</h3><div>The incidence of SSNHL per 1000 individuals was lower in the delivery group (1.08–1.17) compared to the control group (1.52–1.80) each year. In the delivery group, SSNHL occurred most frequently in the 30–34 age group during the third trimester of pregnancy and the postpartum period. The proportion of patients with SSNHL with comorbidities such as hypertension, diabetes, and dyslipidemia was higher in the delivery group than in the control group.</div></div><div><h3>Conclusions</h3><div>Using the longest follow-up period and the largest population in South Korea, we found that pregnancy and childbirth did not increase the risk of SSNHL, which is consistent with the results of previous population-based studies. Our findings provide insights into the etiology of SSNHL and highlight the need for further research to better understand the underlying mechanisms and risk factors associated with SSNHL.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 2","pages":"Article 104600"},"PeriodicalIF":1.8,"publicationDate":"2025-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy analysis of intratympanic injection of dexamethasone at different concentrations for the treatment of unilateral idiopathic sudden sensorineural hearing loss","authors":"Shi-yi Wang ,&nbsp;Wen-ting Fu ,&nbsp;Meng Yu ,&nbsp;Aidong Sun ,&nbsp;Jingwu Sun ,&nbsp;Guang Li","doi":"10.1016/j.amjoto.2025.104603","DOIUrl":"10.1016/j.amjoto.2025.104603","url":null,"abstract":"<div><h3>Objective</h3><div>Our study tried to evaluate and compare the therapeutic efficacy of intratympanic injection of dexamethasone (DEX) at different concentrations for the treatment of idiopathic sudden sensorineural hearing loss (ISSNHL).</div></div><div><h3>Methods</h3><div>A prospective randomized controlled study was conducted on 203 patients with unilateral ISSNHL. Patients were divided into four groups: the control group (n = 47, systemic treatment only), the high-concentration group (n = 51, intratympanic injection of DEX 20 mg/ml), the medium-concentration group (n = 55, 10 mg/ml), and the low-concentration group (n = 50, 5 mg/ml). Pure tone audiometry (PTA) thresholds were measured before treatment and on the 10th day post-treatment, with a follow-up period of 2 months. Hearing gains and efficacy rates were compared among the groups.</div></div><div><h3>Results</h3><div>Significant differences were observed in PTA thresholds before and after treatment in all four groups (<em>P</em> &lt; 0.05), indicating that both systemic therapy and intratympanic injection were effective. The overall efficacy rate and hearing gain were higher in the intratympanic injection groups compared to the control group, but the differences were not statistically significant. Specifically, the control group achieved an efficacy rate of 57.4 % with a hearing gain of 11.25 ± 10.00 dB HL. The intratympanic injection groups showed an overall efficacy rate of 67.3 % and a hearing gain of 12.50 ± 10.94 dB HL, with subgroup results as follows: low-concentration group (62.0 %, 12.50 ± 11.56 dB HL), medium-concentration group (69.1 %, 11.25 ± 13.75 dB HL), and high-concentration group (70.6 %, 12.50 ± 8.75 dB HL). Among patients with severe or profound hearing loss, the high-concentration group exhibited significantly greater hearing gains compared to the control group, while no significant differences were observed in efficacy rates.</div></div><div><h3>Conclusion</h3><div>Combined intratympanic injection of DEX with systemic treatment for SSNHL provides higher hearing gains and efficacy rates compared to systemic treatment alone, though the differences were not statistically significant. In patients with severe or profound hearing loss, intratympanic injection of high-concentration DEX resulted in significantly greater hearing improvement, suggesting a potential therapeutic advantage in this subgroup.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 2","pages":"Article 104603"},"PeriodicalIF":1.8,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143035719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to letter to the editor: Making a racket in America's fastest growing sport: Evaluation of noise exposure in pickleball","authors":"Lawrance Lee,&nbsp;Nauman F. Manzoor","doi":"10.1016/j.amjoto.2025.104602","DOIUrl":"10.1016/j.amjoto.2025.104602","url":null,"abstract":"","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 2","pages":"Article 104602"},"PeriodicalIF":1.8,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor: Making a racket in America's fastest growing sport: Evaluation of noise exposure in pickleball","authors":"Kathleen Romito ,&nbsp;Daniel Fink","doi":"10.1016/j.amjoto.2025.104601","DOIUrl":"10.1016/j.amjoto.2025.104601","url":null,"abstract":"","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 2","pages":"Article 104601"},"PeriodicalIF":1.8,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increase in serum parathyroid hormone level intraoperatively after parathyroidectomy for primary hyperparathyroidism","authors":"Bassam Abboud ,&nbsp;Christopher Abboud","doi":"10.1016/j.amjoto.2025.104598","DOIUrl":"10.1016/j.amjoto.2025.104598","url":null,"abstract":"<div><h3>Background</h3><div>To evaluate the significance of increased of intraoperative parathyroid hormone(IOPTH) 10 min after parathyroidectomy in primary hyperparathyroidism.</div></div><div><h3>Methods</h3><div>All patients underwent parathyroidectomy were retrospectively included. Following the results of IOPTH, three groups were defined: Group 1: increased of IOPTH, Group 2: &lt;50 % decreased of IOPTH, and Group 3: &gt;50 % decreased of IOPTH.</div></div><div><h3>Results</h3><div>Unilateral approach was performed and shifted to bilateral neck exploration(BNE) when indicated. There were single adenoma, double adenomas, and hyperplasia in 84 %, 5 %, and 11 % of cases respectively. We noted that 100 %, 80 %, and 4 % of patients had a polyglandular diseases in Groups 1, 2, and 3 respectively. Double adenoma and hyperplasia were present in 55 %, and 45 %, 22 %, and 58 %, 1 %, and 3 % in Groups 1, 2, and 3 respectively. Female patients represented 55 %, 71 %, and 81 % of patients in Groups 1, 2, and 3 respectively. Cure rate was 99 %.</div></div><div><h3>Conclusions</h3><div>Patients with increased of IOPTH level 10 min after parathyroidectomy had a polyglandular diseases in 100 % of cases and needed BNE.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 2","pages":"Article 104598"},"PeriodicalIF":1.8,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Narrative review of pediatric thyroiditis: Diagnosis and management","authors":"M. Sakharkar ,&nbsp;M. Chavez ,&nbsp;J.R. Levi","doi":"10.1016/j.amjoto.2025.104599","DOIUrl":"10.1016/j.amjoto.2025.104599","url":null,"abstract":"<div><h3>Objective</h3><div>To the best of the authors' knowledge, no current literature reviews on pediatric thyroiditis exist. Our aim is to present relevant and updated information on pediatric thyroiditis subtypes and presentations.</div></div><div><h3>Data sources</h3><div>A narrative review was performed using PubMed and Embase.</div></div><div><h3>Review methods</h3><div>A narrative literature review was performed to find articles in two databases: PubMed and Embase that discussed the various subtypes of thyroiditis in pediatric patients. Relevant key terms included: thyroiditis, pediatric, children, clinical findings, autoimmune thyroiditis, prevalence, and etiology.</div></div><div><h3>Discussion</h3><div>112 articles were included in this review. The subtypes and clinical presentations of pediatric thyroiditis were highlighted to demonstrate that thyroid dysfunction can have unique wide-ranging effects compared to adult populations. Recommendations on diagnostic algorithms, management, and clinical consequences of delayed treatment are discussed.</div></div><div><h3>Conclusions</h3><div>Thyroid hormones are incredibly vital to the development of a child. It is important to identify and prevent long-term consequences clinically by implementing early treatment through awareness of these differences in clinical practice.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 2","pages":"Article 104599"},"PeriodicalIF":1.8,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142998433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro comparison of cerumenolytic efficacy: 2.5 % sodium bicarbonate versus 0.5 % sodium docusate based on cerumen weight gain","authors":"Cheerasook Chongkolwatana ,&nbsp;Paiboon Sureepong ,&nbsp;Kunkanya Chansomboon ,&nbsp;Navarat Kasemsuk ,&nbsp;Chatchawan Srisawat","doi":"10.1016/j.amjoto.2024.104592","DOIUrl":"10.1016/j.amjoto.2024.104592","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to compare the cerumenolytic efficacy of 2.5 % sodium bicarbonate prepared in-house with that of commercially available 0.5 % sodium docusate, utilizing cerumen weight gain and disintegration degree as metrics.</div></div><div><h3>Methods</h3><div>Cerumen samples were collected from patients at an otorhinolaryngology outpatient clinic at a tertiary care hospital. This study evaluated the differences in cerumen weight and degree of disintegration in vitro before and after treatment with cerumenolytic agents at 15 and 30 min and at 1, 2, 4, 6, and 24 h. The agents tested were 2.5 % sodium bicarbonate and 0.5 % sodium docusate. Each experiment was conducted at least five times. We hypothesized that greater weight gain and higher disintegration scores indicate better cerumenolytic efficacy.</div></div><div><h3>Results</h3><div>Both cerumenolytic agents caused significant increases in wet and dry cerumen weights at all time points (<em>P</em> &lt; 0.001). After 24 h, the cerumen weight increased approximately sevenfold from the initial weight. Notably, the weight increased by 50 % of the 24-hour value within the first hour. A comparison of the average weight gain between the 2.5 % sodium bicarbonate and 0.5 % sodium docusate groups revealed no significant differences at any time point (<em>P</em> = 0.406). Similarly, disintegration scores obtained via the 96-well plate method were not significantly different (<em>P</em> = 0.749).</div></div><div><h3>Conclusions</h3><div>In terms of cerumen weight gain and degree of disintegration, the cerumenolytic efficacy of 2.5 % sodium bicarbonate is not inferior to that of 0.5 % sodium docusate. A 1-hour application of a cerumenolytic agent is effective for cerumen removal in outpatient settings.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 2","pages":"Article 104592"},"PeriodicalIF":1.8,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Baseline disease characteristics by surgery history among patients with chronic rhinosinusitis with nasal polyps (CRSwNP) in the global AROMA registry","authors":"Shigeharu Fujieda ,&nbsp;Jayant M. Pinto ,&nbsp;David W. Jang ,&nbsp;Joseph K. Han ,&nbsp;James Mims ,&nbsp;Eugenio De Corso ,&nbsp;Martin Wagenmann ,&nbsp;Changming Xia ,&nbsp;Thomas Plucinak ,&nbsp;Mark Corbett ,&nbsp;Scott Nash ,&nbsp;Amr Radwan","doi":"10.1016/j.amjoto.2024.104596","DOIUrl":"10.1016/j.amjoto.2024.104596","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;The global Assessing long-teRm Outcomes in dupiluMAb (AROMA) registry study aims to characterize the long-term, real-world use of dupilumab in patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This paper reports interim analysis of the baseline characteristics for the first 303 patients enrolled in AROMA.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods and materials&lt;/h3&gt;&lt;div&gt;AROMA is currently ongoing in adult patients with CRSwNP who initiated dupilumab for up to 36 months. This interim analysis describes baseline demographics; systemic/oral corticosteroid (SCS/OCS) and antibiotic use; disease burden; healthcare resource utilization; and medical history. All outcomes are summarized descriptively.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;As of February 2023, AROMA had enrolled 303 patients; 61.7 % had ≥1 prior surgery and 38.3 % were surgery naive. Disease burden at baseline was greatest among patients with prior surgery vs the surgery-naive group: 72.2 % vs 62.9 % had used SCS/OCS, mean University of Pennsylvania Smell Identification Test scores were 10.9 vs 19.2, 31.0 % vs 27.6 % of patients reported severe symptoms, and 47.6 %/16.6 % vs 39.7 %/16.4 % of patients were classified as having severe/very severe disease according to global physician assessment scores. Otolaryngologist/ear, nose, throat and allergist/immunologist were the most common specialties seen regularly by CRSwNP patients (52.8 % and 48.2 %, respectively) and surgery-naive patients were more likely to have visited an allergist than those with prior surgery (66.4 % vs 36.9 %).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;Patients with CRSwNP in AROMA show considerable disease burden at baseline prior to treatment. Those with prior surgery had worse olfaction and an overall worse burden of disease.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Plain language summary&lt;/h3&gt;&lt;div&gt;Chronic rhinosinusitis with nasal polyps (CRSwNP) is a condition characterized by at least 12 weeks of symptoms such as nasal congestion and loss of smell, along with the presence of nasal polyps. Treatment for CRSwNP includes intranasal steroids, but if these cannot control disease, systemic steroids or sinus surgery may be required. Systemic steroids have known side effects and only provide temporary symptom improvement. Following surgery, patients may experience both symptom and polyp recurrence. Dupilumab is a monoclonal antibody that is approved for the treatment of inadequately controlled CRSwNP and can improve disease symptoms such as nasal congestion and loss of smell. This article presents the initial findings from a large global study called AROMA, which observes patients in real-world medical practice for 3 years after initiating dupilumab for CRSwNP. This analysis compares the characteristics of those in the registry who had and had not undergone prior sinonasal surgery for CRSwNP. In this analysis, patients who had previously undergone surgery to remove nasal polyps were more likely to have used steroids for","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 2","pages":"Article 104596"},"PeriodicalIF":1.8,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143073303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative management of pediatric patients undergoing single-stage laryngotracheal reconstruction in the United States: A survey of ASPO members","authors":"Inbal Hazkani ,&nbsp;David Bruss ,&nbsp;Matthew Rowland ,&nbsp;Taher Valika ,&nbsp;Jonathan Ida ,&nbsp;Dana Thompson ,&nbsp;Jennifer Lavin","doi":"10.1016/j.amjoto.2024.104509","DOIUrl":"10.1016/j.amjoto.2024.104509","url":null,"abstract":"<div><h3>Introduction</h3><div>The postoperative management of single-stage laryngotracheal reconstruction (ssLTR) plays a significant role in the surgery's outcomes. The relatively prolonged period in which the child remains intubated and sedated to allow graft healing may be complicated by pulmonary sequelae, airway obstruction, withdrawal symptoms, and eventually failed extubation. This study aims to assess post-ssLTR practices among pediatric otolaryngologists.</div></div><div><h3>Method</h3><div>An electronic cross-sectional survey was distributed to the American Society of Pediatric Otolaryngology (ASPO) members to elucidate current protocols in post-ssLTR practice in the United States.</div></div><div><h3>Results</h3><div>Eighty-six responses were recorded. A majority (60 %; <em>n</em> = 50) reported performing fewer than five ssLTRs per year. The mean time to bronchoscopy following ssLTR was postoperative day 8±3 for ssLTR with a posterior graft and postoperative day 7±3 without a posterior graft. Most practitioners reported avoiding paralytics (61 %, <em>n</em> = 44) unless the desired level of sedation could not be achieved. Most providers utilized pre-pyloric feeding via a nasogastric or gastrostomy tube (<em>n</em> = 50, 72 %). A total of 70 % (<em>n</em> = 49) of respondents use a single medication for acid suppression, whereas 21 % (<em>n</em> = 15) reported dual-acid suppression whether the patient was diagnosed with gastroesophageal reflux prior to surgery or not, regardless of feeding route. Nebulized agents were routinely used, with normal saline (43 %; <em>n</em> = 36) being the most reported agent.</div></div><div><h3>Conclusion</h3><div>The postoperative management after ssLTR varies greatly among pediatric otolaryngologists due to a lack of evidence-based data to support one protocol over the other. Multi-institutional studies should be considered to evaluate current protocols and improve postoperative care.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 1","pages":"Article 104509"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142680605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of response to sialendoscopy for patients with chronic non-obstructive Sialadenitis versus radioiodine induced Sialadenitis","authors":"Xiaoxuan Chen ,&nbsp;Jessica Kim ,&nbsp;Eseosa Odigie ,&nbsp;Ashutosh Kacker ,&nbsp;David I. Kutler","doi":"10.1016/j.amjoto.2024.104518","DOIUrl":"10.1016/j.amjoto.2024.104518","url":null,"abstract":"<div><h3>Objective</h3><div>Radioiodine therapy, commonly used post-thyroidectomy to eliminate residual affected tissue in thyroid cancer patients, can lead to the development of radioiodine induced sialadenitis (RIS). Chronic idiopathic sialadenitis (CIS) is characterized by intermittent and often painful swelling of the salivary glands, not attributed to salivary duct stones. Sialendoscopy is used to treat sialadenitis when conservative management fails. Our objective is to assess patient factors that may predict treatment success, which could help guide expectations on treatment outcomes.</div></div><div><h3>Methods</h3><div>We reviewed 315 patients who underwent sialendoscopy between January 2010 and June 2022. Utilizing the electronic medical record, patient demographics, comorbidities, and post-operative outcomes were reviewed in our REDCap database.</div></div><div><h3>Results</h3><div>We identified 22 patients with RIS and 116 patients with CIS. 28 % of patients with CIS and 41 % of patients with RIS were male. There was no significant difference in mean age (<em>p</em> = 0.37) or gender (<em>p</em> = 0.24) between the two groups. The parotid glands were the primary site of disease in both groups (56 % in CIS group, 73 % in RIS). Age, gender, previous salivary gland surgery, prior radiation, a history of autoimmune disease, and procedures performed during sialendoscopy were not significantly associated with clinical improvement in the CIS group (<em>p</em> &gt; 0.05). 80 % of patients with CIS and 82 % of patients with RIS reported complete resolution or minimal residual symptoms following sialendoscopy.</div></div><div><h3>Conclusion</h3><div>A multitude of predisposing factors can affect a patient's post-operative outcome after sialendoscopy. Sialendoscopy is an effective treatment for patients with RIS or CIS refractory to conservative management.</div></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":"46 1","pages":"Article 104518"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}