American Journal of Otolaryngology最新文献

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Surgical management of iSGS in pregnant patients: Survey among North American expertise centers 妊娠期 iSGS 的手术治疗:北美专业中心调查
IF 1.8 4区 医学
American Journal of Otolaryngology Pub Date : 2024-08-03 DOI: 10.1016/j.amjoto.2024.104459
{"title":"Surgical management of iSGS in pregnant patients: Survey among North American expertise centers","authors":"","doi":"10.1016/j.amjoto.2024.104459","DOIUrl":"10.1016/j.amjoto.2024.104459","url":null,"abstract":"<div><h3>Objective</h3><p>To identify, group and document the surgical management of idiopathic subglottic stenosis (iSGS) in pregnant women among North American centers with expertise in the treatment of airway stenosis.</p></div><div><h3>Background</h3><p>Idiopathic subglottic stenosis is a rare airway disease that primarily affects women in their third to fifth decade of life. Symptoms of iSGS often worsen during pregnancy and can present as a threat to optimal maternal and fetal health; however there is a lack of evidence addressing the management of iSGS in pregnancy.</p></div><div><h3>Study design</h3><p>Cross-Sectional Survey Study.</p></div><div><h3>Methods</h3><p>A twenty-four question survey was designed to query the surgical management, ventilation, and perioperative considerations for pregnant patients with iSGS. Twenty-nine North American academic tertiary care centers with airway surgery expertise were identified. A designated surrogate for each center was contacted by email to distribute and obtain results of the survey.</p></div><div><h3>Results</h3><p>17 centers responded. Most centers include differences in perioperative assessment such as frequency of consultation with a maternal/fetal medicine specialist. There is occasional use of a tocometer and rarely a non-stress test. Ventilation with intermittent jet ventilation or high-flow nasal cannula is favored. The surgical protocols include positional modifications, with pregnant patients in the left lateral decubitus position. The preferred timing for intervention is in the second or third trimester.</p></div><div><h3>Conclusion</h3><p>This is the first national survey describing surgical and perioperative considerations for the pregnant patient with iSGS among centers with airway expertise in the United States and Canada.</p></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S019607092400245X/pdfft?md5=c80abee7139fde3f98e7a62cbc9aaa30&pid=1-s2.0-S019607092400245X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142011211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
U shaped costal cartilage resection to reduce donor site morbidity U 型肋软骨切除术,降低供体部位的发病率。
IF 1.8 4区 医学
American Journal of Otolaryngology Pub Date : 2024-08-03 DOI: 10.1016/j.amjoto.2024.104468
{"title":"U shaped costal cartilage resection to reduce donor site morbidity","authors":"","doi":"10.1016/j.amjoto.2024.104468","DOIUrl":"10.1016/j.amjoto.2024.104468","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of our study is to reduce the complications of pain and chest wall deformity by modifying conventional costal cartilage graft harvesting.</p></div><div><h3>Method</h3><p>In this method while the superior part of the costal cartilage is removed completely, medial, lateral, and inferior parts are excised incompletely and used as a graft. Hence, continuity of the costal cartilage is maintained inferiorly.</p></div><div><h3>Results</h3><p>Nineteen primary and 28 revision rhinoplasty patients were included in the study. There were no donor site complications in the early postoperative period or during one-year follow-up.</p></div><div><h3>Conclusion</h3><p>The modified costal cartilage graft harvesting technique we described is a safe conservative surgical method.</p></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new approach for pharyngocutaneous fistula following total laryngectomy: Endoscopic padlock clip system™ 治疗全喉切除术后咽峡瘘的新方法:内窥镜挂锁夹系统™。
IF 1.8 4区 医学
American Journal of Otolaryngology Pub Date : 2024-08-03 DOI: 10.1016/j.amjoto.2024.104484
{"title":"A new approach for pharyngocutaneous fistula following total laryngectomy: Endoscopic padlock clip system™","authors":"","doi":"10.1016/j.amjoto.2024.104484","DOIUrl":"10.1016/j.amjoto.2024.104484","url":null,"abstract":"","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The tinnitus handicap inventory is a better indicator of the overall status of patients with tinnitus than the numerical rating scale 与数字评级量表相比,耳鸣障碍清单更能反映耳鸣患者的整体状况。
IF 1.8 4区 医学
American Journal of Otolaryngology Pub Date : 2024-08-03 DOI: 10.1016/j.amjoto.2024.104477
{"title":"The tinnitus handicap inventory is a better indicator of the overall status of patients with tinnitus than the numerical rating scale","authors":"","doi":"10.1016/j.amjoto.2024.104477","DOIUrl":"10.1016/j.amjoto.2024.104477","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to explore the electrophysiological characteristics of patients with chronic tinnitus through electrocochleography (ECochG) findings and determine if these findings correlate with specific audiological patterns that could differentiate tinnitus patients from those without this condition.</p></div><div><h3>Materials and methods</h3><p>A retrospective analysis of medical records from patients who visited a tinnitus clinic at a tertiary university hospital between March 2020 and December 2023 was conducted. Inclusion criteria were non-pulsatile subjective tinnitus lasting over three months, and ECochG performed at initial evaluation. Audiological assessments and ECochG results were analyzed, with the SP/AP ratio being a focal point.</p></div><div><h3>Results</h3><p>Among 256 patients, an elevated SP/AP ratio was observed in 37.5 % of patients. No significant difference in ECochG outcomes was noted based on tinnitus laterality. Patients with an elevated SP/AP ratio reported more sleep disturbances, higher depression scores, attention problems, and aural fullness. These patients also exhibited lower loudness discomfort levels and low-frequency hearing losses. Significant correlations were found between elevated SP/AP ratios and DPOAE responses.</p></div><div><h3>Conclusions</h3><p>The findings highlight the SP/AP ratio in ECochG as a valuable biomarker for assessing clinical and psychological aspects of tinnitus, indicating its potential utility in tailoring treatment strategies. Elevated SP/AP ratios were associated with sleep disturbances, depression, attention problems, aural fullness, hyperacusis, and low-frequency hearing loss, suggesting a complex interplay between cochlear pathology and tinnitus perception. This study underscores the need for a nuanced understanding of ECochG results in the clinical evaluation of tinnitus, potentially guiding more personalized management approaches.</p></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0196070924002631/pdfft?md5=8e5e567163666b5ff1930db15951e516&pid=1-s2.0-S0196070924002631-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141905591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative analysis of CO2 laser and ultracision harmonic scalpel for endoscopic treatment of Zenker's diverticulum using a propensity score: A retrospective observational study 使用倾向性评分对二氧化碳激光和超声波谐波手术刀治疗禅克氏憩室进行内窥镜治疗的比较分析:回顾性观察研究
IF 1.8 4区 医学
American Journal of Otolaryngology Pub Date : 2024-08-03 DOI: 10.1016/j.amjoto.2024.104435
{"title":"Comparative analysis of CO2 laser and ultracision harmonic scalpel for endoscopic treatment of Zenker's diverticulum using a propensity score: A retrospective observational study","authors":"","doi":"10.1016/j.amjoto.2024.104435","DOIUrl":"10.1016/j.amjoto.2024.104435","url":null,"abstract":"<div><h3>Objectives</h3><p>Zenker's diverticulum (ZD) is a progressive condition that can cause dysphagia and aspiration. Endoscopic cricopharyngeal myotomy (ECPM) is the gold standard treatment for ZD, but there are various techniques available. We aimed to compare the efficacy and safety of the ultrasonic harmonic scalpel (UHS) versus the CO2 laser (CO2L) for ECPM in ZD.</p></div><div><h3>Design</h3><p>We led an observational study. The main composite outcome consisted in persistence of postoperative dysphagia OR recurrence/reoperation of symptomatic ZD within two years postoperatively. Surgery was considered effective when no dysphagia within two years postoperatively. The secondary outcome was the occurrence of acute mediastinitis within 72 h postoperatively. A propensity score was built to adjust for differences observed between non-randomized groups. Additional sensitivity analyses were performed.</p></div><div><h3>Setting</h3><p>All patients with ECPM surgery for ZD were included from 2011 to 2018 in a single tertiary center. Patients with failure of endoscopic exposition were excluded.</p></div><div><h3>Participants</h3><p>The study included 86 patients who underwent ECPM with either the CO2L (<em>n</em> = 53) or UHS (<em>n</em> = 33) technique. ZD size and other demographic variables were comparable between the groups.</p></div><div><h3>Main outcome measures</h3><p>UHS had superior efficacy compared to CO2L (relative risk of failure = 0.29; 95 % confidence interval: 0.05–1.0; <em>p</em> = 0.05), but there was a higher incidence of mediastinitis in the UHS group (12 % vs. 4 %), although this was not statistically significant.</p></div><div><h3>Results and conclusion</h3><p>The UHS technique appears to be an effective technique for ECPM in ZD patients but its safety remains to explore by further larger studies.</p></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142122613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect and safety of perioperative ibuprofen administration in pediatric tonsillectomy: A systematic review and meta-analysis 小儿扁桃体切除术围手术期布洛芬用药的效果和安全性:系统回顾和荟萃分析。
IF 1.8 4区 医学
American Journal of Otolaryngology Pub Date : 2024-08-03 DOI: 10.1016/j.amjoto.2024.104461
{"title":"Effect and safety of perioperative ibuprofen administration in pediatric tonsillectomy: A systematic review and meta-analysis","authors":"","doi":"10.1016/j.amjoto.2024.104461","DOIUrl":"10.1016/j.amjoto.2024.104461","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to evaluate the safety and efficacy of perioperative ibuprofen administration by conducting a meta-analysis of pertinent literature.</p></div><div><h3>Methods</h3><p>We conducted a comprehensive review of studies sourced from PubMed, SCOPUS, Embase, Web of Science, and Cochrane databases. The studies covered the period from database inception to June 2024. A perioperative ibuprofen administration group was compared to a control group administered either saline, acetaminophen, paracetamol, or opioids. The primary outcome was post-tonsillectomy bleeding that was categorized into overall bleeding and further classified as type 1 (observed at home or evaluated in the emergency department without additional intervention), type 2 (necessitating readmission for observation), and type 3 (requiring a return to the operating room for hemorrhage control). Morbidity incidence rates for postoperative nausea and vomiting were also assessed. The secondary outcomes assessed were postoperative pain management and the frequency of analgesic drug usage. Postoperative pain management was assessed from the incidence of emergency department visits or nurses' calls for pain independent of the presence or absence of dehydration.</p></div><div><h3>Results</h3><p>Twenty-two studies with 27,149 patients were included and reviewed for this meta-analysis. Post-tonsillectomy bleeding (OR = 0.9954, 95 % CI [0.8800; 1.1260], I<sup>2</sup> = 0.0 %) was not significantly higher in the ibuprofen administration group compared to the control group. In subgroup analysis of post-tonsillectomy bleeding severity, ibuprofen caused clinically insignificant type 1 post-tonsillectomy bleeding that did not require intervention (OR = 1.1310 [0.7398; 1.7289]). Clinically significant bleeding requiring hospital admission (type 2) or surgical control (type 3) was not observed. Administration of ibuprofen has demonstrated efficacy in reducing the need for analgesic drugs (OR = 0.4734, 95 % CI [0.2840; 0.7893]; I<sup>2</sup> = 19.8 %) and is associated with a significant decrease in the incidence of postoperative nausea and vomiting (OR = 0.4886, 95 % CI [0.3156; 0.7562], I<sup>2</sup> = 34.3 %).</p></div><div><h3>Conclusion</h3><p>This study demonstrated that administration of ibuprofen for pediatric tonsillectomy did not increase the incidence of clinically significant postoperative bleeding. Ibuprofen administration decreased the incidence and severity of postoperative pain, nausea, and vomiting.</p></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative care for children after ventilation tube surgery: A qualitative study of parents' experiences over time in Norway 儿童通气管手术后的术后护理:挪威家长的长期经验定性研究。
IF 1.8 4区 医学
American Journal of Otolaryngology Pub Date : 2024-08-03 DOI: 10.1016/j.amjoto.2024.104457
{"title":"Postoperative care for children after ventilation tube surgery: A qualitative study of parents' experiences over time in Norway","authors":"","doi":"10.1016/j.amjoto.2024.104457","DOIUrl":"10.1016/j.amjoto.2024.104457","url":null,"abstract":"<div><h3>Objective</h3><p>To explore the parents' experience of postoperative care during the first two years after ventilation tube (VT) surgery in a setting where the check-ups were conducted either by otolaryngologists or their regular general practitioner (GP).</p></div><div><h3>Methods</h3><p>55 individual interviews of parents at up to three different time points (&lt;1, 6, and 24 months) after their child received VT-surgery, analyzed with reflexive thematic analysis.</p></div><div><h3>Results</h3><p><em>1. Parents' trust in the healthcare system and responsibility for booking check-ups.</em> Nearly all parents seemed to maintain trust in the healthcare system and felt safeguarded regardless of where they had their check-ups. Still, they would prefer otolaryngologist-led care if they could choose from the top shelf. They took responsibility for seeking healthcare when needed and experienced that their GP referred their child if necessary. <em>2. As time goes by, parental worries are reduced.</em> Most experienced that their child stayed healthy after surgery, and their demand for postoperative check-ups decreased. For the children who faced ongoing issues, most parents experienced that their child's challenges had been handled professionally, and they became less worried. Some parents attribute other diagnoses to their child's behavior or speech delays, refining their understanding of their child's condition. <em>3. The desire for closure.</em> Parents sought reassurance about their child's recovery and desired professional evaluation for closure. While some advocated for audiometry, others trusted their own assessments about hearing. The transition to school marked a pivotal time, prompting concerns about social inclusion.</p></div><div><h3>Conclusion</h3><p>Overall, the parents experienced that their child was safeguarded irrespective of whether postoperative care was provided by otolaryngologists or GPs. Still, many preferred check-ups by an otolaryngologist. The parental worries and focus on the VTs were reduced as time went by after surgery, but even so many wanted a ‘closure’ to be sure that the hearing was as good as it could be and the VTs rejected. We advocate for an individualized approach to postoperative care that addresses specific medical needs without imposing unnecessary check-ups.</p></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0196070924002436/pdfft?md5=305d13313ec11f18c0c5f06194fa8e56&pid=1-s2.0-S0196070924002436-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of tailor-made notched music training for primary tinnitus: A systematic review and meta-analysis 量身定制的凹槽音乐训练对原发性耳鸣的疗效:系统回顾与荟萃分析。
IF 1.8 4区 医学
American Journal of Otolaryngology Pub Date : 2024-08-03 DOI: 10.1016/j.amjoto.2024.104467
{"title":"Efficacy of tailor-made notched music training for primary tinnitus: A systematic review and meta-analysis","authors":"","doi":"10.1016/j.amjoto.2024.104467","DOIUrl":"10.1016/j.amjoto.2024.104467","url":null,"abstract":"<div><h3>Objective</h3><p>We systematically reviewed and meta-analyzed the efficacy of Tailor-Made Notched Music Training (TMNMT) for primary subjective tinnitus in adults. The main goal was to evaluate TMNMT's impact on tinnitus symptoms.</p></div><div><h3>Methods</h3><p>Following PRISMA guidelines, we included randomized and non-randomized trials. Studies considered involved adults with primary subjective tinnitus treated with TMNMT alone or combined with other therapies. Bias risk was assessed using the Cochrane RoB 2 and ROBINS-I tools. Comprehensive database searches were conducted, and relevant data were extracted and analyzed.</p></div><div><h3>Results</h3><p>Three studies (total: 99 TMNMT patients, 109 sound therapy) were meta-analyzed. Using THI scores, the Forest plot showed no significant difference in tinnitus distress between TMNMT and listening to music groups (<em>p</em> &gt; 0.05), with low study heterogeneity (I2 = 0 %).</p></div><div><h3>Conclusion</h3><p>While TMNMT offers a non-invasive approach with a potential to reduce tinnitus distress, it did not significantly outperform the only listening to music. More research is needed to optimize TMNMT for tinnitus management and to better document its safety profile.</p></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of surgery combined with photodynamic therapy for recurrent respiratory papillomatosis 手术联合光动力疗法治疗复发性呼吸道乳头状瘤病的疗效
IF 1.8 4区 医学
American Journal of Otolaryngology Pub Date : 2024-08-02 DOI: 10.1016/j.amjoto.2024.104454
{"title":"Effectiveness of surgery combined with photodynamic therapy for recurrent respiratory papillomatosis","authors":"","doi":"10.1016/j.amjoto.2024.104454","DOIUrl":"10.1016/j.amjoto.2024.104454","url":null,"abstract":"<div><h3>Objective</h3><p>This study aims to analyze the safety and effectiveness of a new model of surgery combined with Photodynamic therapy for treating Recurrent Respiratory Papillomatosis (RRP).</p></div><div><h3>Methods</h3><p>Review the case data of patients with RRP who opted for comprehensive surgery combined with Photodynamic therapy at the Nanjing BenQ Medical Center, from January 2021 to May 2023. The efficacy of this program was evaluated by comparing the annual number of surgeries and Derkay scores before and after the surgery.</p></div><div><h3>Results</h3><p>A total of 23 RRP patients were included in the study. After treatment, the recurrence rate was 65.2 % (15/23), with an average recurrence time of 94.3 ± 50.8 days. The average Derkay score at the time of recurrence was significantly lower than the average pre-treatment Derkay score (<em>P</em> &lt; 0.001). The average annual recurrence rate before treatment was 2.2 ± 1.3, compared to 1.5 ± 1.5 after treatment, with no significant difference (<em>P</em> = 0.16). However, subgroup analysis revealed a significant decrease in the annual recurrence rate of adult-onset RRP after treatment (<em>P</em> = 0.01). The most common adverse reaction was mild pharyngeal pain (11/23). There were 3 cases of new-onset vocal cord adhesions. No patients experienced serious respiratory-related adverse reactions, anesthesia-related adverse reactions, or systemic phototoxic reactions.</p></div><div><h3>Conclusion</h3><p>In conclusion, this study indicates that surgery combined with Photodynamic therapy (PDT) might be a safe and effective option for treating RRP, especially in patients with Adult-Onset Recurrent Respiratory Papillomatosis (AORRP).</p></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141978120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oncological outcomes of partial thickness calvarial resection for locally advanced scalp malignancies 局部晚期头皮恶性肿瘤的部分厚度颅骨切除术的肿瘤治疗效果。
IF 1.8 4区 医学
American Journal of Otolaryngology Pub Date : 2024-08-02 DOI: 10.1016/j.amjoto.2024.104456
{"title":"Oncological outcomes of partial thickness calvarial resection for locally advanced scalp malignancies","authors":"","doi":"10.1016/j.amjoto.2024.104456","DOIUrl":"10.1016/j.amjoto.2024.104456","url":null,"abstract":"<div><h3>Objective</h3><p>Traditionally, locally advanced scalp malignancies have been managed through composite, full-thickness calvarial resection. The aim of this study is to explore the oncologic outcomes of partial calvarial resection for locally invasive scalp malignancies without medullary space invasion, employing a burr-down approach.</p></div><div><h3>Study design</h3><p>Retrospective case series.</p></div><div><h3>Setting</h3><p>Tertiary referral center.</p></div><div><h3>Methods</h3><p>This study analyzed records of 26 adult patients diagnosed with scalp cancer that spread to the calvarial region. Data collected included demographics, medical history, adjuvant therapy details, imaging, surgical outcomes, and postoperative oncological results.</p></div><div><h3>Results</h3><p>26 patients with cancerous scalp lesions necessitating calvarial resection for deep margin control were identified in 22 men and 4 women. Mean age at diagnosis was 72.7 years. The most common histopathological diagnosis was Squamous cell carcinoma (<em>n</em> = 16). Partial removal of the calvarial lesions was achieved in all patients without any intraoperative complications. Twelve patients received adjuvant therapy consisting of the following modalities: radiation (6), chemotherapy (1), immunotherapy (1), a combination of immunotherapy and radiation (2), and a combination of chemotherapy and radiotherapy (2). There was a total of 7 recurrences: local (<em>n</em> = 3,11.5 %), regional (n = 3,11.5 %), distal (<em>n</em> = 1,3.8 %). Long term local control was achieved in (<em>n</em> = 23,88.4 %) of patients. The mean time of follow-up was 19.1 months, and the mean time to recurrence was 15.1 months.</p></div><div><h3>Conclusion</h3><p>Partial calvarial resection represents a viable, safe, and effective surgical technique for cancerous tissue removal, reducing risks associated with full thickness calvarial resection, and enhancing soft tissue healing when compared to the established gold standard.</p></div>","PeriodicalId":7591,"journal":{"name":"American Journal of Otolaryngology","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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