Stress biology最新文献

{"title":"The transcription factor SbbHLH168 enhances salt tolerance by coordinating ion homeostasis and lignin content in sorghum.","authors":"Simin Li, Zishuo Han, Rui Liu, Zengting Chen, Xuemei Wang, Na Sui, Zhiying Zhao","doi":"10.1007/s44154-026-00330-4","DOIUrl":"10.1007/s44154-026-00330-4","url":null,"abstract":"<p><p>Soil salinization is an escalating global threat to crop productivity. Here, we demonstrate that the sorghum bHLH transcription factor SbbHLH168 is a central regulator of salt-stress tolerance. SbbHLH168 is nuclear-localized, constitutively expressed in all organs and rapidly up-regulated by NaCl. Overexpression of SbbHLH168 in either Arabidopsis or sorghum conferred markedly higher biomass retention, longer roots, lower relative electrical conductivity, less accumulation of superoxide and H₂O₂, and lower Na⁺/K⁺ ratio through decreased Na⁺ accumulation under salt stress, whereas VIGS silent groups displayed the opposite phenotype. qRT-PCR and biochemical assays demonstrated that SbbHLH168 up-regulates key lignin-biosynthetic genes (SbC4H, SbF5H, SbCOMT1) and increases root lignin content under salt stress, thereby reinforcing cell-wall integrity and limiting ion leakage. Furthermore, yeast two-hybrid and BiFC assays confirmed that SbbHLH168 interacts with SbbHLH35 in the nucleus, indicating that SbbHLH168's functional activity depends on heterodimerization with SbbHLH35. Collectively, SbbHLH168 integrates ion homeostasis, ROS scavenging and lignin content to confer salt tolerance, providing a direct gene target for molecular breeding of resilient sorghum cultivars.</p>","PeriodicalId":74874,"journal":{"name":"Stress biology","volume":"6 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13388629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148537868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Review: Genomic insights into the adaptive traits and stress resistance in modern horses.","authors":"Halima Jafari, Belete Kuraz Abebe, Li Cong, Zulfiqar Ahmed, Wang Zhaofei, Minhao Sun, Gemingguli Muhatai, Lei Chuzhao, Ruihua Dang","doi":"10.1007/s44154-026-00327-z","DOIUrl":"10.1007/s44154-026-00327-z","url":null,"abstract":"","PeriodicalId":74874,"journal":{"name":"Stress biology","volume":"6 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13381396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148521566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reconstruction of the raffinose family oligosaccharide pathway in maize improves heat stress tolerance.","authors":"Zhongchun Dong, Tao Li, Xudong Li, Dan Li, Xianfei Shi, Jiahao Chai, Lynnette M A Dirk, A Bruce Downie, Tianyong Zhao","doi":"10.1007/s44154-026-00326-0","DOIUrl":"10.1007/s44154-026-00326-0","url":null,"abstract":"<p><p>Raffinose family oligosaccharides (RFOs), primarily raffinose and stachyose, are crucial for plant abiotic stress tolerance. Raffinose is synthesized by RAFFINOSE SYNTHASE (RAFS) from galactinol and sucrose, whereas stachyose can be produced by STACHYOSE SYNTHASE (STS) from galactinol and raffinose. While Arabidopsis possesses functional RAFS and STS genes and produces both raffinose and stachyose, maize lacks both a functional STS gene and endogenous stachyose. Here, we show that Arabidopsis STACHYOSE SYNTHASE (AtSTS) is induced by heat stress, and its overexpression and subsequent stachyose accumulation enhance heat tolerance. To extend the RFOs pathway in maize, we introduced the AtSTS expression cassette into the maize genome. The resulting transgenic maize lines accumulated stachyose and exhibited improved heat tolerance. Under heat stress, stachyose amounts in these lines increased significantly, likely due to the induction of endogenous ZmRAFS and subsequent protein and raffinose production, the latter serving as the STS substrate. Compared with wild-type controls, transgenic maize seedlings showed reduced leaf damage, higher survival, and lower ion leakage under high-temperature conditions. The application of exogenous stachyose similarly improved heat tolerance in wild-type maize, providing further evidence of its protective function. Moreover, AtSTS overexpression reduced reactive oxygen species (ROS) accumulation, indicating that stachyose helps mitigate oxidative damage. These findings establish stachyose as a contributor to heat stress resilience and propose a promising strategy for improving crop tolerance to increasing global temperatures.</p>","PeriodicalId":74874,"journal":{"name":"Stress biology","volume":"6 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13376108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effector FpECIR from Fusarium pseudograminearum targets wheat ethylene signaling pathway to suppress plant immunity.","authors":"Jiangang Kang, Yun Li, Limin Wang, Zhifang Wang, Cong Chen, Xinlong Wang, Ziming Wang, Shengli Ding, Honglian Li, Haiyang Li","doi":"10.1007/s44154-026-00311-7","DOIUrl":"10.1007/s44154-026-00311-7","url":null,"abstract":"<p><p>Fusarium pseudograminearum (F. pseudograminearum) is the main causal agent of Fusarium Crown Rot (FCR) posing a severe threat to wheat yield. Effectors, as one class of weapons of phytopathogens, help pathogens infect their hosts by disturbing plant immunity. In this study, we identified a secreted effector, FpECIR, which has no functional domains, suppresses INF1-triggered cell death in Nicotiana benthamiana. Once translocated into wheat cells, FpECIR (without signal peptide) interacts with TaPLATZ2B, and silencing TaPLATZ2B and its alleles makes wheat more susceptible to F. pseudograminearum. Deletion of residues 29-35 of FpECIR disrupted its interaction with TaPLATZ2B, and eliminated its ability to suppress INF1-induced cell death. The pathogenicity of deletion mutants ΔFpecir on wheat coleoptiles was significantly reduced. Analysis of transcriptome data showed that infection with the ΔFpecir strain triggered the upregulation of defense-related genes in wheat coleoptiles, many of which were functionally enriched in hormone signaling pathways. qRT-PCR results revealed that FpECIR suppressed the expression of TaPLATZ2B and of genes related to ethylene signaling pathway. Furthermore, EMSA experiment result proved that FpECIR can inhibit the ability of TaPLATZ2B binding with the promoter region of ethylene response factors (TaERF020L). Suppressing the transcription levels of genes related to ethylene biosynthesis made the wheats more susceptible to FCR. Overall, the results showed that FpECIR plays an important role in the pathogenicity of F. pseudograminearum, and that the integrity of FpECIR is necessary for its interaction with TaPLATZ2B and for its suppression of INF1-induced cell death. Additionally, FpECIR not only affects the expression of TaPLATZ2B but also inhibits the function of TaPLATZ2B to regulate plant defense response through ethylene signaling pathways.</p>","PeriodicalId":74874,"journal":{"name":"Stress biology","volume":"6 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13328696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148371335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BUI1 coordinates actin cytoskeleton remodeling and ROS homeostasis to confer broad-spectrum disease resistance in rice.","authors":"Hui Lin, Kaixuan Cui, Jingyi Wang, Yanlong Jin, Xi Zhang, Yiduo Lu, Xuanxuan Wu, Li Zhang, Shasha Liu, Jiyun Liu, Qun Li, Yiwen Deng, Weibing Yang, Zuhua He, Mingjun Gao","doi":"10.1007/s44154-026-00321-5","DOIUrl":"10.1007/s44154-026-00321-5","url":null,"abstract":"<p><p>The cytoskeleton functions as a dynamic intracellular structural scaffold, enabling cells to rapidly respond to biotic and abiotic stresses. During plant innate immunity, the cytoskeleton undergoes significant actin remodeling. Using the rice-Magnaporthe oryzae pathosystem, we demonstrate that pattern-triggered immunity (PTI) induces a rapid and transient actin filament reorganization dependent on the Class II formin protein BENT UPPERMOST INTERNODE1 (BUI1). Disruption of actin filaments using latrunculin B significantly enhances host susceptibility to the blast fungus M. oryzae. Importantly, the bui1 mutant exhibits compromised resistance not only to blast but also to the bacterial blight pathogen Xanthomonas oryzae pv. oryzae and the sheath blight fungus Rhizoctonia solani. We identify that this enhanced susceptibility to multiple pathogens stems from increased ROS scavenging activity in bui1, mediated by upregulation of peroxidase-encoding genes and consequent reduction in H₂O₂ accumulation. Furthermore, genetic analyses reveal that BUI1 acts downstream of the immunity suppressor RESISTANCE OF RICE TO DISEASES1 (ROD1), as the bui1 mutation compromises rod1-mediated broad-spectrum resistance. Our findings establish BUI1 as a key regulator linking cytoskeletal reorganization to receptor-mediated immune signaling and ROS homeostasis during plant-pathogen interactions, providing new insights into the integration of actin dynamics with plant defense mechanisms.</p>","PeriodicalId":74874,"journal":{"name":"Stress biology","volume":"6 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13328597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148371293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bax inhibitor-1 confers resistance to Phytophthora parasitica and is antagonized by RTP1 in Arabidopsis.","authors":"Yujing Fang, Jing Zhang, Xianxian Gao, Shuhan Guo, Xiaoyin Xu, Bianbian Wang, Qing Zheng, Weixing Shan, Xiaoyu Qiang","doi":"10.1007/s44154-026-00318-0","DOIUrl":"10.1007/s44154-026-00318-0","url":null,"abstract":"<p><p>Plant immunity is closely intertwined with endoplasmic reticulum (ER) stress and regulated cell death. Here, we identify the ER-localized cell death regulator Bax Inhibitor-1 (BI-1) as a critical executor of resistance against Phytophthora parasitica in Arabidopsis, whose activity is antagonized by the susceptibility factor RTP1. RTP1 negatively modulates resistance to P. parasitica via ER stress and cell death regulation, yet its downstream coordinators remain unclear. We show that BI-1 expression is significantly elevated in rtp1 mutants during early colonization. Cell viability assays reveal BI-1 is essential for RTP1-mediated cell death suppression, as rtp1 bi-1 double mutants exhibit restored cell death. Pathogenicity assays demonstrate BI-1 confers resistance required for the rtp1-mediated immunity: rtp1 bi-1 mutants show increased susceptibility, reduced expression of ER stress-responsive immune genes (WRKY33, CBP60g, MYB51) and PR1, and abolished flg22-triggered ROS burst. Mechanistically, RTP1 interacts with BI-1 and reduces its protein accumulation through a proteasome-independent pathway, thereby antagonizing BI-1 function. Conversely, activated forms of ER stress transducers bZIP60 and bZIP28 bind and co-activate the BI-1 promoter. Collectively, BI-1 serves as a key node in ER stress-associated immunity, post-translationally antagonized by RTP1 and transcriptionally driven by bZIP60/bZIP28. This study establishes the RTP1-BI-1 module as a pivotal interface linking ER stress perception to immune execution, offering a refined framework for engineering broad-spectrum disease resistance in crops.</p>","PeriodicalId":74874,"journal":{"name":"Stress biology","volume":"6 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13291311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148304288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stratification overcomes ABA-mediated seed dormancy by uncoupling RGL2/ABI5 inhibition from α-amylase expression.","authors":"Yuan Tian, Qin-Lai Liu, Mo-Xian Chen, Ying-Gao Liu","doi":"10.1007/s44154-026-00312-6","DOIUrl":"10.1007/s44154-026-00312-6","url":null,"abstract":"<p><p>Cold-pretreatment (stratification) is widely employed to overcome seed dormancy and enhance germination, however, its underlying molecular mechanisms remain elusive. We tested the hypothesis that stratification alleviates the repression of α-amylase expression, a critical step for endosperm starch mobilization during germination. Stratification at 4 °C effectively overcame dormancy in wild-type Arabidopsis thaliana, the ABA-catabolism mutant cyp707a2, the GA-insensitive mutant sleepy1, and the cyp707a2 sleepy1 double mutant, but failed to rescue the dormancy phenotype of the GA-biosynthesis mutant ga3ox1. Moreover, stratification markedly promoted starch hydrolysis by increasing both the transcript abundance and the enzymatic activity of α-amylase in freshly harvested seeds of wild-type and in those mutants exhibiting elevated endogenous ABA or treated with exogenous ABA. Concomitantly, stratification substantially suppressed the expression of RGL2, a DELLA protein that represses GA signaling, and ABI5, a key ABA-responsive transcription factor. Collectively, our data indicates that stratification initiates GA biosynthesis, thereby relieving RGL2-mediated repression of α-amylase expression. Secondly, stratification mitigates ABA-imposed inhibition of germination without alleviating the suppressive effect of ABA on post-germinative seedling development.</p>","PeriodicalId":74874,"journal":{"name":"Stress biology","volume":"6 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13287508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chromium propionate enhanced the production performance of yellow-feathered broilers under chronic heat stress exposure by improving intestinal health.","authors":"Jinglong Chen, Chuangchuang Lei, Xuming Guo, Dan Shao, Changzheng Guo, Shourong Shi","doi":"10.1007/s44154-026-00320-6","DOIUrl":"10.1007/s44154-026-00320-6","url":null,"abstract":"<p><p>Heat stress is one of the key factors affecting broiler production. This study aimed to investigate the protective effects and underlying mechanisms of chromium propionate (CrP) against heat stress in broilers. A total of 180 yellow-feathered broilers were randomly divided into 3 groups, with 6 replicates per group and 10 broilers per replicate. The CON and HS groups were fed with a basic diet, while the PAC group was supplemented with 0.2 mg/kg CrP. Following pre-feeding for 7 days, HS and PAC groups were exposed to cyclic HS (8 h at 30, 32, and 34 °C, respectively) for two weeks, while the control group was maintained at 26 ℃ ± 1 ℃. The experiment was designed in accordance with a randomized block design, and data were analyzed by one-way ANOVA. The results demonstrated that dietary supplementation with CrP eased heat stress-induced reductions in BW and ADG as well as increased the feed conversion ratio. Heat stress considerably decreased gut length and V/C across all intestinal segments. Moreover, CrP suppressed heat stress-induced increases in serum corticosterone and lipopolysaccharide levels while enhancing intestinal glutathione peroxidase activity. Gene expression analysis of jejunal mucosa revealed that CrP downregulated heat stress-induced upregulation of heat shock proteins and inflammation-related genes COX2 and NLRP3 while enhancing the expression of Mucin2, Occludin and ZO-1. Analysis of 16S rRNA sequencing revealed distinct differences in microbial composition and potential functional shifts among groups. At the genus level, heat stress decreased Alistipes relative abundance along with marked increases in Lactobacillus count; conversely, CrP reversed these trends. LEfSe identified Lactobacillus and Parabacteroides as the predominant bacteria in the HS group, while Gemmatimonas and Cetobacterium predominated the PAC group. Functional prediction analyses indicated that heat stress suppressed carbohydrate and amino acid metabolism while enhancing RNA degradation pathways; these effects were effectively reversed by CrP supplementation. Further correlation analyses revealed positive associations between Alistipes and BW, ADG and ADFI, and negative correlations with HSPs. By contrast, Lactobacillus and Parabacteroides were negatively correlated with BW and ADG, and positively correlated with HSPs. In conclusion, dietary supplementation with CrP considerably enhances growth performance, promotes intestinal repair and restores homeostasis in heat-stressed broilers.</p>","PeriodicalId":74874,"journal":{"name":"Stress biology","volume":"6 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13287288/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcriptomic insights into the biocontrol mechanism of Trichoderma spp. against Fusarium wilt in melon.","authors":"Meriem Miyassa Aci, Polina C Tsalgatidou, Konstantinos Krommydas, Anastasia Boutsika, Costas Delis, Ourania I Pavli, Leonardo Schena, Antonios Zambounis","doi":"10.1007/s44154-026-00315-3","DOIUrl":"10.1007/s44154-026-00315-3","url":null,"abstract":"<p><p>Fusarium wilt (FW), caused by Fusarium oxysporum f. sp. melonis (FOM), is a devastating disease severely impacting global melon (Cucumis melo L.) production. Biocontrol agents such as Trichoderma species, offer a sustainable alternative to chemical fungicides, yet their precise molecular mechanisms remain underexplored. In this study, we tested the antifungal efficacy of a commercial formulation combining two Trichoderma strains (Trichoderma asperellum ICC012 and Trichoderma gamsii ICC080) against FOM and investigated the molecular mechanisms underlying the melon roots Trichoderma-induced responses. Through phenotypic screening, RNA sequencing, and a Weighted Gene Co-expression Network Analysis (WGCNA) we demonstrated that Trichoderma pre-treatment significantly mitigates FW symptoms and orchestrates a robust defense response in melon roots. Our analysis revealed specific transcriptional reprogramming, including the upregulation of key hub genes such as NAC domain-containing protein 2, dehydration-responsive element-binding protein 1A (DREB1A), trihelix transcription factor GT-3b, and a caffeoylshikimate esterase-like encoding gene involved in lignin biosynthesis. Furthermore, critical pathways significantly enriched in Trichoderma-treated roots included phenylpropanoid biosynthesis, MAPK signaling pathway, and plant-pathogen interaction, alongside defense-related processes like zeatin and tryptophan biosynthesis and ABC transporter activity. These molecular reconfigurations highlight the complex signaling networks activated by Trichoderma spp., leading to enhanced immunity against FOM. Our findings provide crucial molecular insights into Trichoderma-mediated biocontrol, elucidating specific genetic and metabolic modulations in melon roots. This research paves the way for targeted breeding strategies and advanced industrial applications of Trichoderma spp. for effective and sustainable management of Fusarium wilt in melon crops.</p>","PeriodicalId":74874,"journal":{"name":"Stress biology","volume":"6 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13287304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Advances in genetic and molecular mechanisms of crop resistance to stalk rot.","authors":"Yueqi Kang, Mingxiu Ruan, Qinhan Hu, Zihao Gui, Jinyan Zhou, Jianbo Yao, Yuanyuan Cao, Ting Ding, Bo Wang, Fengquan Liu, Haiyang Jiang, Guichun Wu, Leiming Wu","doi":"10.1007/s44154-026-00322-4","DOIUrl":"10.1007/s44154-026-00322-4","url":null,"abstract":"","PeriodicalId":74874,"journal":{"name":"Stress biology","volume":"6 1","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13241353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148166117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}