Alcohol and alcoholism最新文献_第7页

Alcohol to-go sales policies at on-premise drinking establishments near large public US universities during the COVID-19 pandemic 在 COVID-19 大流行期间，美国大型公立大学附近的店内酒水销售政策

IF 2.8 4区医学

Alcohol and alcoholism Pub Date : 2024-04-18 DOI: 10.1093/alcalc/agae023

Erika M Rosen, Andrew Walker, Pamela J Trangenstein, Cassidy R LoParco, Melvin D Livingston, Adam E Barry, Matthew E Rossheim

{"title":"Alcohol to-go sales policies at on-premise drinking establishments near large public US universities during the COVID-19 pandemic","authors":"Erika M Rosen, Andrew Walker, Pamela J Trangenstein, Cassidy R LoParco, Melvin D Livingston, Adam E Barry, Matthew E Rossheim","doi":"10.1093/alcalc/agae023","DOIUrl":"https://doi.org/10.1093/alcalc/agae023","url":null,"abstract":"Aims Sweeping policy changes during the COVID-19 pandemic increased alcohol availability through permitted to-go sales, potentially posing unique risks to college students. While to-go sales may make binge drinking more convenient, little remains known about these practices. Therefore, this study aimed to assess whether drinking establishments’ to-go sales practices are associated with their other operational practices and state policy. Method This cross-sectional analysis included 221 randomly selected bars, nightclubs, and restaurants within two miles of a large public university. Telephone interviews assessed establishment practices, and the Alcohol Policy Information System provided state alcohol to-go laws. Regression models tested whether establishment to-go sales practices were associated with their business practices (logistic regression) and state policy (generalized estimating equations). Results Nearly one-half (44.8%) of drinking establishments sold alcohol to-go. Establishments with higher vodka prices had nearly 30% higher odds of selling spirits to-go (aOR = 1.29) and establishments offering happy hours specials had more than twice the odds of selling beer (aOR = 2.22), wine (aOR = 2.53), and spirits to-go (aOR = 2.60). Additionally, establishments that implemented physical distance requirements had higher odds of selling wine to-go (aOR = 3.00). State to-go laws were associated with higher odds of selling wine (aOR = 3.99) and spirits to-go (aOR = 5.43) in the full sample and beer to-go (aOR = 4.92) in urban counties. Conclusions Establishments that sell alcohol to-go tend to engage in other practices designed to drive sales. Evaluations of alcohol to-go sales laws on risky consumption among priority populations, including college students, are urgently needed to inform decisions about how to appropriately regulate sales.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"1 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140627921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reductions in World Health Organization risk drinking level are associated with improvements in sleep problems among individuals with alcohol use disorder 降低世界卫生组织规定的危险饮酒量与改善饮酒障碍患者的睡眠问题有关

IF 2.8 4区医学

Alcohol and alcoholism Pub Date : 2024-04-12 DOI: 10.1093/alcalc/agae022

Christian C Garcia, Dylan K Richards, Felicia R Tuchman, Kevin A Hallgren, Henry R Kranzler, Henri-Jean Aubin, Stephanie S O’Malley, Karl Mann, Arnie Aldridge, Michaela Hoffman, Raymond F Anton, Katie Witkiewitz

{"title":"Reductions in World Health Organization risk drinking level are associated with improvements in sleep problems among individuals with alcohol use disorder","authors":"Christian C Garcia, Dylan K Richards, Felicia R Tuchman, Kevin A Hallgren, Henry R Kranzler, Henri-Jean Aubin, Stephanie S O’Malley, Karl Mann, Arnie Aldridge, Michaela Hoffman, Raymond F Anton, Katie Witkiewitz","doi":"10.1093/alcalc/agae022","DOIUrl":"https://doi.org/10.1093/alcalc/agae022","url":null,"abstract":"Aims Among individuals with alcohol use disorder (AUD), sleep disturbances are pervasive and contribute to the etiology and maintenance of AUD. However, despite increased attention toward the relationship between alcohol use and sleep, limited empirical research has systematically examined whether reductions in drinking during treatment for AUD are associated with improvements in sleep problems. Methods We used data from a multisite, randomized, controlled trial that compared 6 months of treatment with gabapentin enacarbil extended-release with placebo for adults with moderate-to-severe AUD (N = 346). The Timeline Follow-back was used to assess WHO risk drinking level reductions and the Pittsburgh Sleep Quality Index was used to assess sleep quality over the prior month at baseline and the end of treatment. Results Sleep problem scores in the active medication and placebo groups improved equally. Fewer sleep problems were noted among individuals who achieved at least a 1-level reduction (B = −0.99, 95% confidence interval (CI) [−1.77, −0.20], P = .014) or at least a 2-level reduction (B = −0.80, 95% CI [−1.47, −0.14], P = .018) in WHO risk drinking levels at the end of treatment. Reductions in drinking, with abstainers excluded from the analysis, also predicted fewer sleep problems at the end of treatment (1-level: B = −1.01, 95% CI [−1.83, −0.20], P = .015; 2-level: B = −0.90, 95% CI [−1.59, −0.22], P = .010). Conclusions Drinking reductions, including those short of abstinence, are associated with improvements in sleep problems during treatment for AUD. Additional assessment of the causal relationships between harm-reduction approaches to AUD and improvements in sleep is warranted.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"7 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140575640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary symptoms associated with heavy alcohol consumption among people living with HIV: an analysis of the NHANES 1999–2010 与艾滋病病毒感染者大量饮酒有关的肺部症状：对 1999-2010 年国家健康调查（NHANES）的分析

IF 2.8 4区医学

Alcohol and alcoholism Pub Date : 2024-04-06 DOI: 10.1093/alcalc/agae021

Moses New-Aaron, Mohleen Kang, Samantha M Yeligar

{"title":"Pulmonary symptoms associated with heavy alcohol consumption among people living with HIV: an analysis of the NHANES 1999–2010","authors":"Moses New-Aaron, Mohleen Kang, Samantha M Yeligar","doi":"10.1093/alcalc/agae021","DOIUrl":"https://doi.org/10.1093/alcalc/agae021","url":null,"abstract":"Aim This matched case–control study aimed to provide epidemiologic evidence of increased burden of respiratory symptoms and pulmonary function decline among people living with human immunodeficiency virus (HIV) and a history of heavy alcohol consumption. Methods Cases were participants with HIV (PWH; n = 75, 33%), and controls were participants without HIV (PWoH; n = 150, 67%). PWH were matched to PWoH by age and sex in the ratio of 1:2. Eligible participants responded to the respiratory health National Health and Nutrition Examination Survey questionnaire [prolonged coughs (≥3 months), bringing up of phlegm (≥3 months), and a history of wheezing or whistling in the chest (past year)]. The effects of both alcohol and HIV on participants’ pulmonary function were determined using linear regression analysis. Results History of heavy alcohol consumption was more prevalent among PWH (40%) compared to PWoH (27%). PWH who had a history of heavy alcohol consumption had a higher prevalence of coughing most days (45% vs. 4%, P = .0010), bringing up phlegm most days (31% vs. 0%, P = .0012), and wheezing or whistling in the chest (40% vs. 20%, P = .058) compared to participants who did not heavily consume alcohol. Furthermore, a history of heavy alcohol consumption was associated with decreased forced expiratory volume (ml) in 1 s/forced vital capacity among PWH (β = − 0.098 95% C.I. −0.16, −0.04, P = .03) after adjusting for having smoked at least 100 cigarettes in life. Conclusion A history of heavy alcohol use increased respiratory symptoms and suppressed pulmonary function among people living with HIV. This study provides epidemiological evidence of the respiratory symptom burden of people living with HIV who have a history of heavy alcohol consumption.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"93 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140575643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How frequently is alcohol advertised on television in Canada?: A cross-sectional study 加拿大电视上的酒类广告频率如何？横断面研究

IF 2.8 4区医学

Alcohol and alcoholism Pub Date : 2024-04-04 DOI: 10.1093/alcalc/agae020

Elise Pauzé, Adena Pinto, Monique Potvin Kent

{"title":"How frequently is alcohol advertised on television in Canada?: A cross-sectional study","authors":"Elise Pauzé, Adena Pinto, Monique Potvin Kent","doi":"10.1093/alcalc/agae020","DOIUrl":"https://doi.org/10.1093/alcalc/agae020","url":null,"abstract":"Aims Alcohol marketing is a commercial driver of alcohol use, including among youth. This study sought to quantify and characterize alcohol advertising on broadcast television in Canada. Methods Open-source television program logs for January to December 2018 submitted to the Canadian Radio-television and Telecommunications Commission by 147 stations with alcohol advertisements were analyzed. Results Overall, 501 628 alcohol advertisements were broadcast. Four companies accounted for 83% of advertisements, namely, Anheuser-Busch in Bev (33.7%), Molson Coors (22.7%), Diageo (16.1%), and Arterra Wines Canada (10.8%). On conventional stations, advertising was highest on French-language stations [Median (Mdn) = 3224; interquartile range (IQR) = 2262] followed by those with programming in foreign/mixed languages (Mdn = 2679; IQR = 219) and English-language stations (Mdn = 1955; IQR = 1563). On speciality stations, advertising was most frequent on those primarily focused on sports programming (Mdn = 8036; IQR = 7393), movies and scripted shows (Mdn = 7463; IQR = 5937), and cooking (Mdn = 5498; IQR = 4032). On weekdays, 33% of alcohol ads aired from 6 to 9 a.m. and 3 to 9 p.m. and on weekends, 52% aired from 6 a.m. to 9 p.m. when children or adolescents are more likely to be watching television. On youth-oriented stations (n = 4), 7937 alcohol advertisements were broadcast with most airing from 9 p.m. to midnight (44–45%) or 12–6 a.m. (50%) on both weekdays and weekends. Conclusions While few alcohol advertisements were broadcast on youth-oriented stations, young people in Canada are likely exposed to such advertising on programming intended for older or general audiences (e.g. sports). More research is needed to ascertain the extent to which broadcast television constitutes a source of alcohol advertising exposure among youth and to inform policies aimed at protecting them from the influence of such exposure.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"68 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140575802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Positive allosteric modulators of the GABAB receptor: a new class of ligands with therapeutic potential for alcohol use disorder GABAB 受体的正性异构调节剂：一类具有治疗酒精使用障碍潜力的新型配体

IF 2.8 4区医学

Alcohol and alcoholism Pub Date : 2024-04-03 DOI: 10.1093/alcalc/agae018

Giancarlo Colombo

{"title":"Positive allosteric modulators of the GABAB receptor: a new class of ligands with therapeutic potential for alcohol use disorder","authors":"Giancarlo Colombo","doi":"10.1093/alcalc/agae018","DOIUrl":"https://doi.org/10.1093/alcalc/agae018","url":null,"abstract":"Background Positive allosteric modulators (PAMs) of the GABAB receptor constitute a new class of GABAB-receptor ligands. GABAB PAMs reproduce several pharmacological effects of the orthosteric GABAB receptor agonist, baclofen, although displaying a better safety profile. Aims This paper reviews the reducing or, frequently, even suppressing effects of all GABAB PAMs tested to date on multiple alcohol-related behaviours in laboratory rodents exposed to validated experimental models of human alcohol use disorder. Results Acute or repeated treatment with CGP7930, GS39783, BHF177, rac-BHFF, ADX71441, CMPPE, COR659, ASP8062, KK-92A, and ORM-27669 reduced excessive alcohol drinking, relapse- and binge-like drinking, operant alcohol self-administration, reinstatement of alcohol seeking, and alcohol-induced conditioned place preference in rats and mice. Conclusions These effects closely mirrored those of baclofen; notably, they were associated to remarkably lower levels of tolerance and toxicity. The recent transition of ASP8062 to clinical testing will soon prove whether these highly consistent preclinical data translate to AUD patients.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"61 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140575712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Keeping you connected or keeping you addicted? Weekly use of social media platforms is associated with hazardous alcohol use and problem gambling among adults. 让你保持联系还是让你沉迷其中？成年人每周使用社交媒体平台与危险饮酒和问题赌博有关。

IF 2.8 4区医学

Alcohol and alcoholism Pub Date : 2024-03-16 DOI: 10.1093/alcalc/agae024

Iina Savolainen, Atte Oksanen

{"title":"Keeping you connected or keeping you addicted? Weekly use of social media platforms is associated with hazardous alcohol use and problem gambling among adults.","authors":"Iina Savolainen, Atte Oksanen","doi":"10.1093/alcalc/agae024","DOIUrl":"https://doi.org/10.1093/alcalc/agae024","url":null,"abstract":"Aims: A wide variety of social media platforms exist, each offering tailored solutions to attract specific target audiences based on their social media needs and interests. This diversity may pose a risk factor for the development or perpetuation of harmful behaviors. Research has established a connection between social media use and increased health risk behaviors. This six-wave exploratory longitudinal study investigated the associations between active social media use, hazardous alcohol use, and problem gambling among adult social media users.Methods: Data were collected via surveys in 6-month intervals, starting in March-April 2021 (T1: N = 1530; Mage = 46.67; SD = 16.42; 50.33% male). Of the T1 respondents, 58.10% participated in T6 (n = 889). Measures included the frequency of use of different social media platforms, the 3-item Alcohol Use Disorders Identification Test (AUDIT-C), and the Problem Gambling Severity Index (PGSI). Hybrid multilevel regression models were used for analyses.Results: We found positive within-person effects of weekly Facebook use and between-person effects of weekly use of Facebook, TikTok, and gambling-related online communities on drinking. These results suggest an increase in hazardous alcohol consumption over time among the platforms' active users. Weekly Instagram use had a negative between-person effect on hazardous alcohol use. Individuals using TikTok or gambling communities weekly were more prone to problem gambling compared to non-weekly users.Conclusions: There are risks involved in the active use of some social media services among adult users. Prevention work, including digital health interventions, should be targeted according to the appropriate user group.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11017780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the relationship between solitary drinking and living without other adults on alcohol consumption during the COVID-19 pandemic. 探索 COVID-19 大流行期间独自饮酒与无其他成年人陪伴生活对酒精消费的影响。

IF 2.8 4区医学

Alcohol and alcoholism Pub Date : 2024-03-16 DOI: 10.1093/alcalc/agae013

Yvette Mojica-Perez, Bree Willoughby, Dan Anderson-Luxford, Claire Wilkinson, Emmanuel Kuntsche, Sarah Callinan, Alison Ritter

{"title":"Exploring the relationship between solitary drinking and living without other adults on alcohol consumption during the COVID-19 pandemic.","authors":"Yvette Mojica-Perez, Bree Willoughby, Dan Anderson-Luxford, Claire Wilkinson, Emmanuel Kuntsche, Sarah Callinan, Alison Ritter","doi":"10.1093/alcalc/agae013","DOIUrl":"10.1093/alcalc/agae013","url":null,"abstract":"Aims: The COVID-19 pandemic presents the opportunity to learn about solitary drinking as many people were forced to spend time at home. The aim of this study is to examine the relationship between solitary drinking and living without other adults on alcohol consumption.Methods: A longitudinal study with four survey waves (between May and November 2020) obtained seven-day drinking diary data from Australian adults living in New South Wales. In May, a convenience sample of 586 participants (Mage = 35.3, SD = 14.8; 65.3% women) completed the first wave. Participants then completed a survey in June (n = 319, 54.4% response rate), July/August (n = 225, 38.4% response rate), and November (n = 222, 37.9% response rate). Information about alcohol consumption including risky drinking (more than four drinks on one occasion), household structure, solitary drinking, and demographics were collected. We conducted random-effects panel bivariate and multivariable regression analyses predicting the number of standard drinks and risky drinking.Results: Participants with solitary drinking occasions consumed more and had more risky drinking occasions than participants with no solitary drinking occasions, which was also found to be the case during lockdown. Living without other adults was associated with less consumption and less risky drinking than living with other adults. However, participants who lived without other adults and had frequent solitary drinking occasions (solitary drinking in >50% drinking occasions) reported more consumption than participants without a solitary drinking occasion.Conclusions: Individuals who consume alcohol alone and live without other adults or spend long periods of time at home may be more at risk of alcohol-related harm.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10945291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140142615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolation and loneliness as pathways to heavy drinking early in the pandemic. 隔离和孤独是导致大流行病早期大量饮酒的途径。

IF 2.8 4区医学

Alcohol and alcoholism Pub Date : 2024-03-16 DOI: 10.1093/alcalc/agae012

Michael Fendrich, Jessica Becker, Beth S Russell, Crystal L Park

{"title":"Isolation and loneliness as pathways to heavy drinking early in the pandemic.","authors":"Michael Fendrich, Jessica Becker, Beth S Russell, Crystal L Park","doi":"10.1093/alcalc/agae012","DOIUrl":"10.1093/alcalc/agae012","url":null,"abstract":"Introduction: social isolation and forced quarantines during the early phases of the COVID-19 pandemic coincided with a steep and persistent rise in alcohol consumption among US adults. While the association between loneliness and drinking is well established, less is known about the impact of social isolation (a known correlate of loneliness) and the interplay between these two variables in relation to drinking.Methods: we recruited US adults using the MTurk platform for an online survey in early April 2020. The initial survey was followed up with a second wave, 30 days later in mid to late May. Data from the current analyses focus on this second wave of data collection.Results: we found significant direct effects on heavy drinking for both social isolation (c' = 0.495; P < .01) and loneliness (b = 0.071; P < .05). We also found a significant indirect path from social isolation to heavy drinking through social isolation's impact on elevating loneliness (a = 0.919; P < .001). The indirect effect of social isolation on the composite measure of heavy drinking was 0.0652 (0.919 × 0.071) and was significant at the 0.05 level after bootstrapping estimates of the variance were constructed.Conclusions: those most isolated early in the pandemic were at increased risk for heavy drinking, in part because their social isolation led to increased loneliness. Post-pandemic research is needed to explore whether the relationships that stemmed from social isolation during the pandemic led to a persistent pattern of behavioral risk that maintained high rates of heavy drinking.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10973935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140304367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations between alcohol taxes and varied health outcomes among women of reproductive age and infants. 酒精税与育龄妇女和婴儿各种健康结果之间的关系。

IF 2.8 4区医学

Alcohol and alcoholism Pub Date : 2024-03-16 DOI: 10.1093/alcalc/agae015

Meenakshi S Subbaraman, Alex Schulte, Nancy F Berglas, William C Kerr, Sue Thomas, Ryan Treffers, Guodong Liu, Sarah C M Roberts

{"title":"Associations between alcohol taxes and varied health outcomes among women of reproductive age and infants.","authors":"Meenakshi S Subbaraman, Alex Schulte, Nancy F Berglas, William C Kerr, Sue Thomas, Ryan Treffers, Guodong Liu, Sarah C M Roberts","doi":"10.1093/alcalc/agae015","DOIUrl":"10.1093/alcalc/agae015","url":null,"abstract":"Objective: No studies have examined whether alcohol taxes may be relevant for reducing harms related to pregnant people's drinking.Method: We examined how beverage-specific ad valorem, volume-based, and sales taxes are associated with outcomes across three data sets. Drinking outcomes came from women of reproductive age in the 1990-2020 US National Alcohol Surveys (N = 11 659 women $le$ 44 years); treatment admissions data came from the 1992-2019 Treatment Episode Data Set: Admissions (N = 1331 state-years; 582 436 pregnant women admitted to treatment); and infant and maternal outcomes came from the 2005-19 Merative Marketscan® database (1 432 979 birthing person-infant dyads). Adjusted analyses for all data sets included year fixed effects, state-year unemployment and poverty, and accounted for clustering by state.Results: Models yield no robust significant associations between taxes and drinking. Increased spirits ad valorem taxes were robustly associated with lower rates of treatment admissions [adjusted IRR = 0.95, 95% CI: 0.91, 0.99]. Increased wine and spirits volume-based taxes were both robustly associated with lower odds of infant morbidities [wine aOR = 0.98, 95% CI: 0.96, 0.99; spirits aOR = 0.99, 95% CI: 0.98, 1.00] and lower odds of severe maternal morbidities [wine aOR = 0.91, 95% CI: 0.86, 0.97; spirits aOR = 0.95, 95% CI: 0.92, 0.97]. Having an off-premise spirits sales tax was also robustly related to lower odds of severe maternal morbidities [aOR = 0.78, 95% CI: 0.64, 0.96].Conclusions: Results show protective associations between increased wine and spirits volume-based and sales taxes with infant and maternal morbidities. Policies that index tax rates to inflation might yield more public health benefits, including for pregnant people and infants.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10945295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140142614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying excessive chronic alcohol use with phosphatidylethanol in patients with suspected severe injury-results from the IDART study. 用磷脂酰乙醇识别疑似重伤患者长期过度饮酒--IDART 研究的结果。

IF 2.8 4区医学

Alcohol and alcoholism Pub Date : 2024-03-16 DOI: 10.1093/alcalc/agae014

Benedicte M Jørgenrud, Camilla C Bråthen, Jo Steinson Stenehjem, Thomas Kristiansen, Leiv Arne Rosseland, Stig Tore Bogstrand

{"title":"Identifying excessive chronic alcohol use with phosphatidylethanol in patients with suspected severe injury-results from the IDART study.","authors":"Benedicte M Jørgenrud, Camilla C Bråthen, Jo Steinson Stenehjem, Thomas Kristiansen, Leiv Arne Rosseland, Stig Tore Bogstrand","doi":"10.1093/alcalc/agae014","DOIUrl":"10.1093/alcalc/agae014","url":null,"abstract":"Introduction: Acute and chronic alcohol use are well-known risk factors for accidents and injuries, and concurrent psychoactive drug use can increase injury risk further. Phosphatidylethanol (PEth) 16:0/18:1 is a biomarker used to determine alcohol consumption the previous 3-4 weeks. The aim was to investigate the prevalence of chronic alcohol use in trauma patients, as determined by PEth 16:0/18:1 concentrations, and how excessive chronic alcohol use relate to demographic variables, injury mechanisms and drug use.Setting: Patients received at Norwegian trauma hospitals from March 2019 to February 2020. The study is part of the Impairing Drugs and Alcohol as Risk factors for Traumatic Injuries study.Methods: All patients aged ≥ 16 years received with trauma team were included in the study. Data on injury date and mechanism, gender and age was registered. Blood samples were analyzed for 22 psychoactive medicinal and illicit drugs, ethanol and phosphatidylethanol 16:0/18:1. Regression analyses were conducted to assess associations between alcohol use and gender, age, injury mechanism and drug use.Results and conclusion: Of the 4845 patients included in the study, 10% had PEth 16:0/18:1 concentration ≥ 600 nM (~430 ng/mL), indicative of excessive chronic alcohol use. Being male, between 44-61 years old, involved in violence, and testing positive for medicinal drugs was associated with excessive chronic alcohol use.Excessive chronic alcohol use was common among males, middle-aged, patients with violence as injury mechanism and those with medicinal drug use. These findings emphasize the need to detect and treat excessive chronic alcohol use among trauma patients.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 3","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10945293/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140142616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0