From childhood trauma to alcohol use disorder severity - significance of depressive symptoms and expectations towards analgesic effects of alcohol.

IF 2.1 4区医学 Q3 SUBSTANCE ABUSE

Alcohol and alcoholism Pub Date : 2024-05-14 DOI:10.1093/alcalc/agae041

Justyna Zaorska, Jakub Skrzeszewski, Paweł Kobyliński, Elisa Maria Trucco, Marcin Wojnar, Maciej Kopera, Andrzej Jakubczyk

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引用次数: 0

Abstract

Aims: The objective of the current study was to describe and analyse associations between childhood emotional abuse, severity of depressive symptoms, and analgesic expectations of drinking in individuals with alcohol use disorder (AUD).

Methods: A total of 240 individuals aged 43.85 ± 11.0 with severe AUD entering an inpatient, abstinence-based, and drug-free treatment program were assessed. The data on AUD severity, depressive symptoms, expectations towards the analgesic effects of alcohol and childhood emotional trauma was collected using questionnaire measures. The PROCESS SPSS macro for serial mediation with bootstrapping was used to test whether current severity of depressive symptoms and expectations towards analgesic effects of alcohol use serially mediated the association between childhood emotional abuse on AUD symptom severity.

Results: There was evidence for two simple mediated effects, whereby the severity of depressive symptoms mediated the association between childhood emotional abuse on AUD symptom severity, and expectations towards analgesic effects of alcohol mediated the association between childhood emotional abuse on AUD symptom severity. There was also evidence to support serial mediation whereby both severity of depressive symptoms and expectations towards analgesic effects of alcohol mediated the association between childhood emotional abuse on AUD symptom severity.

Conclusions: It might be clinically relevant to address experiences of childhood emotional trauma, as well as individual expectations of analgesic effects of alcohol, in AUD treatment programs.

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从童年创伤到酒精使用障碍的严重程度--抑郁症状和对酒精镇痛效果的期望的重要性。

目的：本研究旨在描述和分析酒精使用障碍（AUD）患者的童年情感虐待、抑郁症状严重程度和饮酒镇痛期望之间的关联：共对 240 名年龄在 43.85 ± 11.0 岁之间、进入以禁欲为基础的无药物治疗项目的重度 AUD 患者进行了评估。采用问卷调查法收集有关 AUD 严重程度、抑郁症状、对酒精镇痛效果的期望以及童年情感创伤的数据。使用PROCESS SPSS宏进行序列调解和引导，以检验当前抑郁症状的严重程度和对饮酒镇痛效果的期望是否序列调解了童年情感虐待与AUD症状严重程度之间的关联：有证据表明存在两种简单的中介效应，即抑郁症状的严重程度中介了童年情感虐待与 AUD 症状严重程度之间的联系，而对酒精镇痛效果的预期中介了童年情感虐待与 AUD 症状严重程度之间的联系。还有证据支持序列中介作用，即抑郁症状的严重程度和对酒精镇痛作用的期望都中介了童年情感虐待与 AUD 症状严重程度之间的联系：结论：在AUD治疗项目中，解决童年情感创伤经历以及个人对酒精镇痛效果的期望可能具有临床意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Alcohol and alcoholism 医学-药物滥用

CiteScore

4.70

自引率

3.60%

发文量

审稿时长

4-8 weeks

期刊介绍： About the Journal Alcohol and Alcoholism publishes papers on the biomedical, psychological, and sociological aspects of alcoholism and alcohol research, provided that they make a new and significant contribution to knowledge in the field. Papers include new results obtained experimentally, descriptions of new experimental (including clinical) methods of importance to the field of alcohol research and treatment, or new interpretations of existing results. Theoretical contributions are considered equally with papers dealing with experimental work provided that such theoretical contributions are not of a largely speculative or philosophical nature.