{"title":"Alcohol effects on interoception shape expectancies and subjective effects: a registered report using the heart rate discrimination task.","authors":"Mateo Leganes-Fonteneau","doi":"10.1093/alcalc/agae025","DOIUrl":"10.1093/alcalc/agae025","url":null,"abstract":"<p><strong>Aims: </strong>Alcohol acutely impacts interoceptive processes, which in turn affect the perception of alcohol effects and the development of alcohol expectancies. However, previous research is limited by the tools used to measure cardiac interoception and subjective alcohol effects. This registered report proposes a re-examination of previous findings using a state-of-the-art measure of interoceptive capacity, the heart rate discrimination task, and measurements of subjective alcohol effects across both ascending and descending limbs.</p><p><strong>Methods: </strong>In a double-blind, placebo-controlled experiment, n = 36 participants were given 0.4 g/kg of ethanol, and a baseline measure of alcohol expectancies was obtained. Changes in interoceptive capacity after beverage administration, along with measures of light-headedness, mood, and biphasic alcohol effects, were assessed over two sessions.</p><p><strong>Hypotheses: </strong>As registered in this secondary data analysis, alcohol was expected to acutely impact different indices of interoceptive capacity, and those changes were hypothesized to correlate with subjective alcohol effects and expectancies. Analyses were conducted only following in-principle acceptance.</p><p><strong>Results: </strong>Alcohol-induced changes in interoceptive capacity predicted the development of light-headedness, stimulation, and negative mood. Changes in interoceptive capacity were also correlated with negative alcohol expectancies, as measured 2 weeks prior to the experiment. These effects were unique to the interoceptive condition, as null effects were observed in an exteroceptive control task.</p><p><strong>Discussion: </strong>This report offers a replication of key previous findings that alcohol impacts interoceptive processes to shape the detection of subjective alcohol effects. We propose that, through repeated drinking occasions, bodily responses feed into the experience of intoxication, shaping future expectancies about alcohol effects.</p>","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141086492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katelyn T Kirk-Provencher, Matthew E Sloan, Keinada Andereas, Cooper J Erickson, Rosa H Hakimi, Anne E Penner, Joshua L Gowin
{"title":"Neural responses to reward, threat, and emotion regulation and transition to hazardous alcohol use.","authors":"Katelyn T Kirk-Provencher, Matthew E Sloan, Keinada Andereas, Cooper J Erickson, Rosa H Hakimi, Anne E Penner, Joshua L Gowin","doi":"10.1093/alcalc/agae043","DOIUrl":"10.1093/alcalc/agae043","url":null,"abstract":"<p><strong>Aims: </strong>Reward processing and regulation of emotions are thought to impact the development of addictive behaviors. In this study, we aimed to determine whether neural responses during reward anticipation, threat appraisal, emotion reactivity, and cognitive reappraisal predicted the transition from low-level to hazardous alcohol use over a 12-month period.</p><p><strong>Methods: </strong>Seventy-eight individuals aged 18-22 with low-level alcohol use [i.e. Alcohol Use Disorder Identification Test (AUDIT) score <7] at baseline were enrolled. They completed reward-based and emotion regulation tasks during magnetic resonance imaging to examine reward anticipation, emotional reactivity, cognitive reappraisal, and threat anticipation (in the nucleus accumbens, amygdala, superior frontal gyrus, and insula, respectively). Participants completed self-report measures at 3-, 6-, 9-, and 12-month follow-up time points to determine if they transitioned to hazardous use (as defined by AUDIT scores ≥8).</p><p><strong>Results: </strong>Of the 57 participants who completed follow-up, 14 (24.6%) transitioned to hazardous alcohol use. Higher baseline AUDIT scores were associated with greater odds of transitioning to hazardous use (odds ratio = 1.73, 95% confidence interval 1.13-2.66, P = .005). Brain activation to reward, threat, and emotion regulation was not associated with alcohol use. Of the neural variables, the amygdala response to negative imagery was numerically larger in young adults who transitioned to hazardous use (g = 0.31), but this effect was not significant.</p><p><strong>Conclusions: </strong>Baseline drinking levels were significantly associated with the transition to hazardous alcohol use. Studies with larger samples and longer follow-up should test whether the amygdala response to negative emotional imagery can be used to indicate a future transition to hazardous alcohol use.</p>","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141490500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justyna Zaorska, Jakub Skrzeszewski, Paweł Kobyliński, Elisa Maria Trucco, Marcin Wojnar, Maciej Kopera, Andrzej Jakubczyk
{"title":"From childhood trauma to alcohol use disorder severity - significance of depressive symptoms and expectations towards analgesic effects of alcohol.","authors":"Justyna Zaorska, Jakub Skrzeszewski, Paweł Kobyliński, Elisa Maria Trucco, Marcin Wojnar, Maciej Kopera, Andrzej Jakubczyk","doi":"10.1093/alcalc/agae041","DOIUrl":"https://doi.org/10.1093/alcalc/agae041","url":null,"abstract":"<p><strong>Aims: </strong>The objective of the current study was to describe and analyse associations between childhood emotional abuse, severity of depressive symptoms, and analgesic expectations of drinking in individuals with alcohol use disorder (AUD).</p><p><strong>Methods: </strong>A total of 240 individuals aged 43.85 ± 11.0 with severe AUD entering an inpatient, abstinence-based, and drug-free treatment program were assessed. The data on AUD severity, depressive symptoms, expectations towards the analgesic effects of alcohol and childhood emotional trauma was collected using questionnaire measures. The PROCESS SPSS macro for serial mediation with bootstrapping was used to test whether current severity of depressive symptoms and expectations towards analgesic effects of alcohol use serially mediated the association between childhood emotional abuse on AUD symptom severity.</p><p><strong>Results: </strong>There was evidence for two simple mediated effects, whereby the severity of depressive symptoms mediated the association between childhood emotional abuse on AUD symptom severity, and expectations towards analgesic effects of alcohol mediated the association between childhood emotional abuse on AUD symptom severity. There was also evidence to support serial mediation whereby both severity of depressive symptoms and expectations towards analgesic effects of alcohol mediated the association between childhood emotional abuse on AUD symptom severity.</p><p><strong>Conclusions: </strong>It might be clinically relevant to address experiences of childhood emotional trauma, as well as individual expectations of analgesic effects of alcohol, in AUD treatment programs.</p>","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141305193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annelien Esselink, Andrea D Rozema, Nathalie Kools, Tim Van Den Berk, Rob H L M Bovens, Jolanda J P Mathijssen
{"title":"Effectiveness of a self-help guide during a temporary alcohol abstinence challenge: a randomized controlled trial.","authors":"Annelien Esselink, Andrea D Rozema, Nathalie Kools, Tim Van Den Berk, Rob H L M Bovens, Jolanda J P Mathijssen","doi":"10.1093/alcalc/agae034","DOIUrl":"10.1093/alcalc/agae034","url":null,"abstract":"<p><strong>Background: </strong>The popularity of temporary abstinence challenges (TACs) concerning alcohol consumption is increasing. Support is found to be essential for participants to help them get through a challenge. This study aimed to evaluate the additional effect of a self-help guide, based on health behaviour theories and behaviour change techniques, on (i) successful completion of a TAC and (ii) changes in drinking refusal self-efficacy (DRSE), behavioural automaticity, craving, and alcohol consumption.</p><p><strong>Methods: </strong>A randomized controlled trial was performed (OSF registries: OSF.IO/B95VU). NoThanks participants received a questionnaire before the TAC (T0) and 8 months after the TAC (T1). Out of a subgroup of 1308 respondents who were interested in additional support, 652 were randomly assigned to receive the guide (experimental group), and 656 did not receive any additional support (control group). Logistic regressions and (generalized) linear mixed model analyses were used.</p><p><strong>Results: </strong>After 8 months, all participants showed a significant decrease in behavioural automaticity, craving, and alcohol consumption, irrespective of group assignment. No significant changes were observed in the DRSE. This degree of change over time in behavioural automaticity, craving, and alcohol consumption did not differ between the experimental and control group. Sensitivity analyses with participants in the experimental group, who differed in exposure to the guide, did not show differences either.</p><p><strong>Conclusion: </strong>The self-help guide, and how it was designed, added no value to the TAC. Future research should focus on more bottom-up, customized support and explore what (different subgroups of) participants think they need as extra support during a TAC.</p>","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11128764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141154480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Morica Hutchison, Sarah Szafranski, Caitlin Titus, Beau Abar, Kenneth R Conner, Stephen Maisto, Tracy Stecker
{"title":"An assessment of beliefs about mental health care among community-based adults with severe, untreated alcohol use disorder.","authors":"Morica Hutchison, Sarah Szafranski, Caitlin Titus, Beau Abar, Kenneth R Conner, Stephen Maisto, Tracy Stecker","doi":"10.1093/alcalc/agae037","DOIUrl":"10.1093/alcalc/agae037","url":null,"abstract":"<p><strong>Objective: </strong>Alcohol use disorder (AUD) is among the most prevalent substance use disorders in the USA. Despite availability of effective interventions, treatment initiation and engagement remain low. Existing interventions target motivation and practical barriers to accessing treatment among individuals established within treatment systems. In contrast, Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) aims to elicit and modify treatment-seeking beliefs to increase treatment-seeking behaviors among treatment-naïve samples. We aim to understand which beliefs were endorsed by those who did/did not initiate treatment, including changes in number of drinking days.</p><p><strong>Method: </strong>We examined treatment seeking beliefs elicited during CBT-TS among community-based adults with moderate-severe AUD with no treatment history. In this study, we discuss which beliefs were modifiable (i.e. those discussed during the intervention among individuals who subsequently attended treatment and may be associated with treatment-seeking behaviors).</p><p><strong>Results: </strong>Of the 194 participants who received the intervention, 16 categories of beliefs were endorsed. Of the 38 participants (19.6%) who attended treatment, the most frequently endorsed belief was 'Not wanting specific types of substance use treatment or supports' (50%), a belief that may inhibit treatment seeking. The idea 'Treatment is positive' (47%) was also frequently cited, a belief that may facilitate treatment seeking.</p><p><strong>Conclusions: </strong>This study describes the beliefs that were more frequently endorsed among adults with moderate-severe, but untreated AUD who reported attending treatment following CBT-TS. Findings point to the potential of discussing and modifying treatment-seeking beliefs among treatment-naïve adults with severe AUD to increase treatment-seeking behaviors.</p>","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141236642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Trine Finanger, Katrine Melby, Olav Spigset, Trine N Andreassen, Stian Lydersen, Ragnhild Bergene Skråstad
{"title":"Relationship between alcohol intake based on daily smartphone-reported consumption and PEth concentrations in healthy volunteers.","authors":"Trine Finanger, Katrine Melby, Olav Spigset, Trine N Andreassen, Stian Lydersen, Ragnhild Bergene Skråstad","doi":"10.1093/alcalc/agae040","DOIUrl":"10.1093/alcalc/agae040","url":null,"abstract":"<p><strong>Aims: </strong>To investigate the association between alcohol consumption registered daily with a digital smartphone-based diary and concentration of phosphatidylethanol (PEth) 16:0/18:1 in a population without a known alcohol use disorder (AUD), and evaluate whether prospective registration of alcohol consumption is better than retrospective registration and if the association between alcohol intake and PEth was affected by sex or body mass index (BMI).</p><p><strong>Methods: </strong>A total of 41 women and 21 men without AUD-diagnosis registered their alcohol consumption prospectively with a digital diary for 14 days, and retrospectively with the Timeline Followback method in the same time interval. PEth was measured before and after the registration period.</p><p><strong>Results: </strong>The correlation between alcohol consumption and PEth varied from 0.65 to 0.87. It did not depend significantly on the reporting method, and was not influenced by sex or BMI. Based on the regression coefficient, a reduction of alcohol consumption by two alcohol units (26 g of pure ethanol) per day would lead to a reduction of the PEth concentration of about 0.1 μmol/l, and vice versa.</p><p><strong>Conclusions: </strong>There was a good correlation between PEth concentration and alcohol consumption, both when alcohol consumption was reported prospectively and retrospectively. The preferred cut-off for PEth should be adjusted to the level of alcohol consumption considered harmful and a purposeful trade-off between sensitivity and specificity. In order to identify persons with a daily alcohol consumption of more than two or three units of alcohol with a sensitivity of 80% or 90%, we suggest a cut-off of around 0.1 μmol/l.</p>","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 4","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11180986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141330197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Profiles and the impact of affective temperaments on alcohol use disorder: a cross-sectional study.","authors":"Kazuhiro Kurihara, Munenaga Koda, Yu Zamami, Hotaka Shinzato, Yoshikazu Takaesu, Tsuyoshi Kondo","doi":"10.1093/alcalc/agae036","DOIUrl":"10.1093/alcalc/agae036","url":null,"abstract":"<p><strong>Aims: </strong>This study aimed to explore the profiles and impact of affective temperaments, together with social and clinical backgrounds, including affective symptoms, in patients with alcohol use disorder (AUD).</p><p><strong>Methods: </strong>This study included 314 low-risk drinkers and 257 patients with AUD. To assess affective temperament, we used the short version of the temperament evaluation of Memphis, Pisa, Paris, and San Diego. To evaluate depressive and mixed symptoms, the quick inventory of depressive symptomatology self-report Japanese version and 12-item questionnaire for the quantitative assessment of the depressive mixed state were used. We compared the profiles of affective temperaments as well as social and clinical backgrounds, including affective symptoms, between the two groups and further performed logistic regression analyses to explore the factors contributing to AUD.</p><p><strong>Results: </strong>Our analysis showed higher cyclothymic, hyperthymic, and irritable temperament scores and lower depressive temperament scores in patients with AUD than that in nonclinical drinkers. Regarding other social and clinical backgrounds, patients with AUD were less educated and employed and more experienced depressive and mixed symptoms. Logistic regression analysis identified hyperthymic temperament as a positive contributor and depressive temperament as a negative contributor to AUD.</p><p><strong>Conclusions: </strong>Our findings indicated potential bipolarity in patients with AUD, as manifested by a more hyperthymic temperament in contrast to less depressive temperament. Despite their self-perceived adaptive temperament profiles, patients showed poorer social outcomes and more affective symptoms. This gap may be partly explained by a lack of insight unique to AUD psychology, which potentially disturbs problem recognition.</p>","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141174154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Natalie Druffner, Donald Egan, Swetha Ramamurthy, Justin O'Brien, Allyson Folsom Davis, Jasmine Jack, Diona Symester, Kelston Thomas, Jayme M Palka, Vishal J Thakkar, Edson Sherwood Brown
{"title":"IQ in high school as a predictor of midlife alcohol drinking patterns.","authors":"Natalie Druffner, Donald Egan, Swetha Ramamurthy, Justin O'Brien, Allyson Folsom Davis, Jasmine Jack, Diona Symester, Kelston Thomas, Jayme M Palka, Vishal J Thakkar, Edson Sherwood Brown","doi":"10.1093/alcalc/agae035","DOIUrl":"10.1093/alcalc/agae035","url":null,"abstract":"<p><strong>Aims: </strong>The aim of the present study was to assess the relationship between adolescent IQ and midlife alcohol use and to explore possible mediators of this relationship.</p><p><strong>Methods: </strong>Study data were from 6300 men and women who participated in the Wisconsin Longitudinal Study of high-school students graduating in 1957. IQ scores were collected during the participants' junior year of high school. In 2004, participants reported the number of alcoholic beverages consumed (past 30 days) and the number of binge-drinking episodes. A multinomial logistic regression was conducted to determine the relationship between adolescent IQ and future drinking pattern (abstainer, moderate drinker, or heavy drinker), and Poisson regression was used to examine the number of binge-drinking episodes. Two mediators-income and education-were also explored.</p><p><strong>Results: </strong>Every one-point increase in IQ score was associated with a 1.6% increase in the likelihood of reporting moderate or heavy drinking as compared to abstinence. Those with higher IQ scores also had significantly fewer binge-drinking episodes. Household income, but not education, partially mediated the relationship between IQ and drinking pattern.</p><p><strong>Conclusions: </strong>The present study suggests that higher adolescent IQ may predict a higher likelihood of moderate or heavy drinking in midlife, but fewer binge-drinking episodes. The study also suggests that this relationship is mediated by other psychosocial factors, specifically income, prompting future exploration of mediators in subsequent studies.</p>","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"59 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141157080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Byron L Zamboanga, Amie R Newins, Janine V Olthuis, Jennifer E Merrill, Heidemarie Blumenthal, Su Yeong Kim, Timothy J Grigsby, Patrick McClain, Dennis McChargue, Miguel Ángel Cano
{"title":"A confirmatory factor analysis of a revised motives for playing drinking games (MPDG-33) scale among university students in the United States","authors":"Byron L Zamboanga, Amie R Newins, Janine V Olthuis, Jennifer E Merrill, Heidemarie Blumenthal, Su Yeong Kim, Timothy J Grigsby, Patrick McClain, Dennis McChargue, Miguel Ángel Cano","doi":"10.1093/alcalc/agae027","DOIUrl":"https://doi.org/10.1093/alcalc/agae027","url":null,"abstract":"Aim Participating in a drinking game (DG) is common practice among university students and can increase students’ risk for heavy drinking. Given the theoretical link between motivations to drink and alcohol use, careful consideration should be given to students’ motivations to play DGs. In this study, we examined the factor structure, internal consistency, and concurrent validity of a revised version of the motives for playing drinking games (MPDG) scale, the MPDG-33. Methods University students (n = 3345, Mage = 19.77 years, SDage = 1.53; 68.8% = women; 59.6% = White) from 12 U.S. universities completed a confidential online self-report survey that included the MPDG-33 and questions regarding their frequency of DG participation and typical drink consumption while playing DGs. Results Confirmatory factor analysis indicated the 7-factor model fit the data adequately, and all items had statistically significant factor loadings on their predicted factor. All subscales had adequate to excellent internal consistency and were positively correlated with the frequency of DG participation and the typical number of drinks consumed while playing DGs (though the correlations were small). Conclusion Findings suggest that the MPDG-33 can be reliably used in research and clinical settings to assess U.S. university students’ motives for playing DGs.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"60 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140834232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joanna Ting Wai Chu, Jessica McCormack, Yannan Jiang, Daniel Walsh, Holly Wilson, Samantha Marsh, Fiona Langridge, Chris Bullen
{"title":"Investigating the relationship between prenatal alcohol exposure and children’s behavioural and emotional development: analysis of the Growing Up in New Zealand study","authors":"Joanna Ting Wai Chu, Jessica McCormack, Yannan Jiang, Daniel Walsh, Holly Wilson, Samantha Marsh, Fiona Langridge, Chris Bullen","doi":"10.1093/alcalc/agae029","DOIUrl":"https://doi.org/10.1093/alcalc/agae029","url":null,"abstract":"Aims To examine the relationship between prenatal alcohol exposure (PAE) and children’s behavioural and emotional development in a large generalizable sample of women and their children in Aotearoa New Zealand. Methods Using data from the Growing Up in New Zealand longitudinal cohort, we investigated the relationship between maternal PAE and behavioural and emotional development in 8-year-old children. We explored secondary outcomes including measures of language, executive function, academic achievement, and adaptive behaviour. Results We found no significant differences in the measures of behavioural and emotional development in children 8 years old based on alcohol consumption. No significant differences in behavioural and emotional development were found based on amount of PAE and when PAE occurred, despite controlling for a range of potential confounding factors, such as neighbourhood deprivation and maternal health measures. PAE was associated with significantly higher scores for parent-rated oral language indicating better oral language. In Māori mothers, PAE was significantly associated with an increased risk of higher scores on two of the Strengths and Difficulties Questionnaire subscales. Conclusions We did not find an association between PAE and behavioural and emotional development in children aged 8 years. PAE and behavioural and emotional development are difficult to measure accurately, and the moderating variables between them are complex. Future analyses will require larger cohorts of mothers and their children using precise measures of PAE and outcomes to enable more precise estimates of association.","PeriodicalId":7407,"journal":{"name":"Alcohol and alcoholism","volume":"6 1","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140812082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}