危险饮酒患者的异常部位血栓形成:叙述性回顾

IF 2.1 4区 医学 Q3 SUBSTANCE ABUSE
Margherita Vergadoro, Luca Spiezia, Alberto Zanetto, Erika Zola, Paolo Simioni
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引用次数: 0

摘要

目的和方法:有害使用酒精在世界范围内构成了一个日益严重的公共卫生问题,它表现为过度消费(急性或慢性),这可能导致成瘾。酒精相关疾病的风险与摄入模式相关,并随着饮酒量的增加而增加。虽然饮酒对缺血性中风和缺血性心脏病的影响有充分的文献记载,但对静脉血栓栓塞的影响尚不清楚。相互矛盾的研究报告称,酒精可能是静脉血栓栓塞的危险因素,或者对静脉血栓栓塞有保护作用。我们的叙述性综述旨在评估危险饮酒个体异常部位静脉血栓形成的风险,因为它可能源于酒精相关的器官损伤(如肝硬化、胰腺炎),并为医生提供一些建议。结果:危险饮酒与异常部位血栓形成之间似乎存在相关性,尽管其潜在机制在很大程度上仍不清楚。结论:在危险饮酒并伴有酒精相关器官损害的受试者中,医生应警惕潜在的血栓形成症状,准备诊断并及时开始适当的抗凝治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unusual-site thrombosis in patients with hazardous alcohol use: a narrative review.

Aims and methods: Hazardous alcohol use poses an increasing public health issue worldwide and it manifests as excessive consumption (acute or chronic), which may lead to addiction. The risk of alcohol-related pathologies correlates with the patterns of intake and increases with the amount of alcohol consumed. While the effects of alcohol consumption on ischemic stroke and ischemic heart disease are well documented, the impact on venous thromboembolism is less clear. Conflicting studies have reported that alcohol may be a risk factor for, or have a protective role against venous thromboembolism. Our narrative review aimed to assess the risk of unusual-site venous thrombosis in individuals with hazardous alcohol use, as it may stem from alcohol-related organ damage (e.g. liver cirrhosis, pancreatitis) as well as provide some suggestions for physicians.

Results: There appears to be a correlation between hazardous alcohol use and unusual-site thrombosis, though the underlying mechanisms are largely still unknown.

Conclusion: In subjects with hazardous alcohol use complicated by alcohol-related organ damage, physicians should be vigilant for potential thrombotic symptoms, and be prepared to diagnose and promptly initiate appropriate anticoagulation therapy.

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来源期刊
Alcohol and alcoholism
Alcohol and alcoholism 医学-药物滥用
CiteScore
4.70
自引率
3.60%
发文量
62
审稿时长
4-8 weeks
期刊介绍: About the Journal Alcohol and Alcoholism publishes papers on the biomedical, psychological, and sociological aspects of alcoholism and alcohol research, provided that they make a new and significant contribution to knowledge in the field. Papers include new results obtained experimentally, descriptions of new experimental (including clinical) methods of importance to the field of alcohol research and treatment, or new interpretations of existing results. Theoretical contributions are considered equally with papers dealing with experimental work provided that such theoretical contributions are not of a largely speculative or philosophical nature.
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