Frontiers in dental medicine最新文献

{"title":"Influencing factors and survival rates in immediate vs. delayed dental implant placement: a six-year retrospective analysis.","authors":"Yanfei Cheng, Zhifen Lai, Weiguang Yu","doi":"10.3389/fdmed.2025.1563641","DOIUrl":"10.3389/fdmed.2025.1563641","url":null,"abstract":"<p><strong>Objective: </strong>This retrospective cohort study aimed to compare survival rates between immediate (≤24 h post-extraction) and delayed (3-4 months post-extraction) dental implants and to identify patient- and site-specific risk factors for implant failure, with emphasis on anatomical site, sex, and osteoporosis.</p><p><strong>Methods: </strong>We analyzed 1,500 implants (300 immediate, 1,200 delayed) from patients treated at the Guangdong Provincial Hospital of Traditional Chinese Medicine (2005-2023). Kaplan-Meier analysis evaluated cumulative survival rates over 72 months, with Cox regression modeling to assess predictors of failure. Propensity score matching (PSM) addressed baseline covariate imbalances.</p><p><strong>Results: </strong>Delayed implants exhibited significantly higher survival rates than immediate implants at 72 months (81.1% vs. 53.2%, <i>p</i> < 0.0001). Survival divergence intensified after 24 months, with delayed implants retaining 979 patients at risk vs. 202 for immediate implants. Mandibular sites consistently outperformed maxillary sites in both strategies (delayed: 88.5% vs. 72.2%; immediate: 70.5% vs. 40.7%, <i>p</i> < 0.0001). Male sex (HR: 1.64, 95% CI: 1.28-1.88; <i>p</i> < 0.001) and osteoporosis (HR: 2.50, 95% CI: 1.17-4.52; <i>p</i> = 0.024) emerged as independent risk factors, while tobacco use, diabetes, and hypertension showed no significant associations. PSM resolved most baseline imbalances, with post-matching standardized mean differences (SMD) <0.1 for key covariates.</p><p><strong>Conclusions: </strong>Delayed implantation at 3-4 months post-extraction provides superior intermediate-term survival, particularly in mandibular sites. Male patients and individuals with osteoporosis face elevated failure risks, warranting tailored clinical protocols. While both strategies remain viable, delayed placement is recommended for high-risk populations to optimize long-term outcomes.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1563641"},"PeriodicalIF":1.5,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soft-tissue modification in Class III non-growing patients treated with clear aligners: a prospective clinical trial.","authors":"R Lione, C Pavoni, F Gazzani, F C De Razza, L Lugli, P Cozza","doi":"10.3389/fdmed.2025.1584088","DOIUrl":"10.3389/fdmed.2025.1584088","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of the present prospective study was to assess the soft tissue modifications induced by camouflage treatment with clear aligners in adult patients with mild Class III malocclusion.</p><p><strong>Methods: </strong>Patients were consecutively enrolled in the study sample according to the following inclusion criteria: adult age (≥19 years), permanent dentition including second permanent molars, skeletal Class I or slight Class III (-2° < difference between sella-nasion^ point A and sella-nasion^ point B < +2°), normal skeletal divergence pattern (SN^GoGn, 27°-37°), Class III canine and molar relationship at baseline (T0) with moderate lower arch crowding (≤+4 mm), and good compliance with aligners and elastics (≥20 h/day). All the participants underwent the lower distalization protocol, which included extraction of the lower third molars before starting treatment and a 50% sequential lower distalization, and Class III intermaxillary elastics (1/4 in., 6.5 oz) from buttons on the upper first molars to precision cuts at the level of the lower canines to reinforce the anchorage. Lateral cephalograms were taken at T0 (before treatment) and at the end of the clear aligner treatment (T1) with an average time interval of 24 ± 6 months. A customized digitization regimen and cephalometric analysis were created to assess the esthetic outcomes at T1. The significance level was set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>The lower distalization supported by Class III elastics resulted in a slight improvement of the facial esthetic profile with no significant changes in the lower third of the face. A mildly better projection of the upper lip was detected at the end of treatment, mainly due to the extensive use of Class III elastics.</p><p><strong>Discussion: </strong>The lower distalization supported by Class III elastics determined slight improvement of the facial aesthetic profile with no significant changes in the lower third of the face. A mild better projection of the upper lip was detected at the end of treatment, mainly due to the extensive use of Class III elastics.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1584088"},"PeriodicalIF":1.5,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring career impact and satisfaction in a graduate program in dentistry.","authors":"Isadora Dos Santos Rotta, Fernando Valentim Bitencourt, Fabrício Mezzomo Collares, Roger Junges, Susana Maria Werner Samuel, Ramona Fernanda Ceriotti Toassi, Cassiano Kuchenbecker Rösing","doi":"10.3389/fdmed.2025.1566272","DOIUrl":"10.3389/fdmed.2025.1566272","url":null,"abstract":"<p><strong>Introduction: </strong>The assessment of student outcomes is essential for monitoring the quality of graduate programs in healthcare sciences. As such, this study focused on developing a self-employed questionnaire that allowed for the evaluation of elements focused on career impact and levels of satisfaction regarding graduate program education. Following, this instrument was utilized in a cross-sectional study design with alumni that had obtained their degree (MSc or PhD) over a 25-year span (1995-2020) from a graduate program in dentistry located in Brazil.</p><p><strong>Methods: </strong>The employed instrument comprised a total of 43 questions presenting a mix of both close and open-ended questions coupled with 5-point Likert scales. The questionnaire was hosted online and a total of 528 alumni were invited to participate through e-mail and social media outreach.</p><p><strong>Results: </strong>376 alumni answered the questionnaire (71.2% response rate). The majority were female (69.9%), and with a MSc (58.5%). Levels of satisfaction towards the program as well the impact in career and life were higher in alumni that had obtained a PhD degree compared to MSc. After obtaining the degree, an increase in involvement in teaching/research positions (3.4% vs 21.5%, <i>p</i> < 001) and a decrease in unemployment (21.9% vs 2.1%, <i>p</i> < 001) were observed. The highest levels of impact were observed regarding the achievement of the professional goals as nearly 90% of the population agreed with this statement.</p><p><strong>Conclusions: </strong>This study highlighted the creation and employment of an assessment tool that can be utilized to monitor the perceptions of student outcomes. Among the findings, a decrease in unemployment and a high degree of career impact and satisfaction were observed in the population of this study. Moving forward, it is essential that monitoring educational outcomes remains a priority worldwide.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1566272"},"PeriodicalIF":1.5,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into periodontal disease: comparative analysis of animal models.","authors":"Binapani Barik, Saurabh Chawla, Bhabani Sankar Satapathy, Swadesh Kumar Pattanik, J Aravind Kumar, Saleh Al-Farraj, Gurudutta Pattnaik, Mika Sillanpää","doi":"10.3389/fdmed.2025.1560101","DOIUrl":"https://doi.org/10.3389/fdmed.2025.1560101","url":null,"abstract":"<p><p>Periodontal disease is a progressive condition characterized by the degradation of gingival tissues, periodontal ligaments, and alveolar bone, often resulting in tooth loss if untreated. Its pathogenesis is influenced by bacterial infections, host immune responses, and environmental factors. While human cell cultures provide insights into cellular mechanisms, animal models play a crucial role in understanding the complex host-pathogen interactions and developing therapeutic interventions. Various species, including rodents, dogs, non-human primates, and mini-pigs, have been employed in periodontal research due to their anatomical and immunological similarities to humans. These models allow the study of disease progression, systemic effects, and potential treatments in a controlled environment. However, challenges such as anatomical differences, ethical concerns, and the difficulty of accurately replicating human periodontal disease remain. Despite these limitations, animal models are indispensable for advancing periodontal research, offering insights into disease mechanisms and contributing to the development of novel therapies. This review evaluates the strengths and limitations of several animal models used in periodontal disease studies, emphasizing the need for further refinement to enhance their relevance to human conditions.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1560101"},"PeriodicalIF":1.5,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12062011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights from the global education survey on the use of VR-haptics in dental education.","authors":"Sompop Bencharit, Barry Quinn, Maria F Sittoni-Pino, Santiago Arias-Herrera, Simona-Georgiana Schick, Sarah Rampf, Samantha Byrne, Muhammad A Shazib, Ulf Örtengren, Walter Yu Hang Lam, Mikko Liukkonen, David Rice, Masako Nagasawa, Amitha Ranauta, Sobia Zafar, Kinga Bágyi, Thomas J Greany, Amirul Faiz Luai, Marit Øilo, Gitana Rederiene, Rebecca Stolberg, Gülsün Gül, Jorge Tricio, Reinhard Chun Wang Chau, Mihaela Pantea, Murat Mutluay, Peter Lingström, Ophir Klein, Sıla Nur Usta, Liisa Suominen, Szabolcs Felszeghy","doi":"10.3389/fdmed.2025.1576646","DOIUrl":"https://doi.org/10.3389/fdmed.2025.1576646","url":null,"abstract":"<p><strong>Background: </strong>Haptics-enhanced virtual reality (VR-haptics), a supplementary tool for traditional oral health training, shows promise in enhancing knowledge acquisition, manual dexterity, performance, and student well-being.</p><p><strong>Aim: </strong>The aim of this study was to understand dental educators' perceptions and needs regarding the acceptability and application of VR-haptics in dental education, as well as to gather suggestions for system improvements.</p><p><strong>Methods: </strong>In this global cross-sectional study, the VR-Haptic Thinkers Consortium used a 28-item online questionnaire distributed to 1,023 participants by August 1, 2024. The survey included questions on general demographics, multiple choice and five-point Likert-style questions, and open-ended questions.</p><p><strong>Results: </strong>A total of 378 responses were collected from 156 institutions. 57% of respondents had a dental doctorate degree and 59% had a PhD. VR-haptic trainers were used more often in preclinical training (94% of responses) than clinical training (46%). The three most common course types with VR-haptics incorporation were restorative, prosthodontic, and endodontic courses. Most respondents thought that the best approach to implementing VR-haptics is alongside phantom head training in the preclinical stage (58%). A third of the feedback on the challenges in VR-haptics utilization in dental training highlighted a need for further hardware and software development, while more than one-fourth cited economic issues in system acquisition and housing, and another one-fourth reported low acceptance of the technology among educators and students. The most mentioned enhancement requests for dental trainers were more diverse training scenarios (20%), improved software (19%) and hardware (19%) elements, and advancements in AI-based personalized training and monitoring (18%). Additionally, 10% of respondents suggested gamification features.</p><p><strong>Conclusions: </strong>VR-haptic technology is constantly evolving and will likely become more and more accepted as an integral part of dental hand skill development to complement traditional preclinical training. Future research and development should emphasize transitioning from preclinical to clinical restorative, prosthodontic, endodontic, and implantology procedures as part of individualized education and patient care.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1576646"},"PeriodicalIF":1.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-use of dentures after tooth loss is associated with elevated sodium/potassium ratios in older adults: a retrospective cohort study.","authors":"Takafumi Abe, Tsuyoshi Hamano, Haruki Usuda, Koichiro Wada, Kenta Okuyama, Kazumichi Tominaga, Shozo Yano, Minoru Isomura","doi":"10.3389/fdmed.2025.1479896","DOIUrl":"https://doi.org/10.3389/fdmed.2025.1479896","url":null,"abstract":"<p><strong>Objective: </strong>An elevated sodium-to-potassium (Na/K) ratio in urine increases the risk of hypertension. Tooth loss in older adults can lead to a diminished nutritional state, including alterations in the Na/K ratio. However, the relationship between denture use and changes in the Na/K ratio among individuals with tooth loss has not been sufficiently explored. This study examined whether denture use modifies the association between tooth loss and changes in the Na/K ratio.</p><p><strong>Methods: </strong>Surveys in 2016 and 2018 included 473 older adults. The Na/K ratio was measured using spot urine tests. A dental hygienist evaluated the number of teeth and the use of dentures. We used generalized linear models to analyze the combined effect of the number of teeth and denture use on changes in the Na/K ratio.</p><p><strong>Results: </strong>Participants without dentures in the 0-19 teeth group showed a significant association with changes in the Na/K ratio (B = 0.635; 95% confidence interval = 0.038, 1.232) compared to those with ≥28 teeth, but denture users with 0-19 teeth did not show significant association. No significant association with changes in the Na/K ratio was observed in denture users and non-users with 20-27 teeth.</p><p><strong>Conclusion: </strong>In non-denture users with fewer than 20 teeth, the Na/K ratio was markedly elevated, but in denture users with fewer than 20 teeth it was not significant. These findings highlight the importance of promoting denture use in older adults with few remaining teeth to maintain their Na/K balance.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1479896"},"PeriodicalIF":1.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive analysis of root canal morphology in relation to root canal treatment failures: a retrospective study.","authors":"Mohmed Isaqali Karobari, Vishnu Priya Veeraraghavan, P J Nagarathna, Sudhir Rama Varma, Jayaraj Kodangattil Narayanan, Santosh R Patil","doi":"10.3389/fdmed.2025.1540038","DOIUrl":"https://doi.org/10.3389/fdmed.2025.1540038","url":null,"abstract":"<p><strong>Background: </strong>Failure of root canal treatment (RCT) significantly affects patient outcomes and dental practice. Understanding the association between root canal morphology and RCT outcomes can help predict treatment success. This study aimed to analyze the predictive role of root canal morphology in RCT failure.</p><p><strong>Methods: </strong>This retrospective study included 224 patients who underwent RCT. Demographic data, tooth type, and root canal morphology were also recorded. Univariate and multivariate logistic regression analyses were performed to identify predictors of RCT failure. Additionally, machine learning algorithms were employed to develop a predictive model that was evaluated using receiver operating characteristic (ROC) curves.</p><p><strong>Results: </strong>Of the 224 RCTs, 112 (50%) were classified as successful and 112 (50%) as failure. Severe canal curvature (<i>p</i> < 0.001) and presence of accessory canals (<i>p</i> = 0.002) were significant predictors of failure. The final predictive model demonstrated an area under the ROC curve (AUC) of 0.83, indicating good accuracy in distinguishing between successful and failed RCTs.</p><p><strong>Conclusion: </strong>These findings underscore the importance of root canal morphology in predicting RCT outcomes. Machine learning approaches can enhance clinical decision making, enabling better treatment planning for patients at a higher risk of RCT failure.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1540038"},"PeriodicalIF":1.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Saccharibacteria</i> (TM7) in saliva and subgingival microbiome as a predictor for gingivitis in individuals with type2 diabetes evaluated by qPCR.","authors":"Boy M Bachtiar, Dicky L Tahapary, Turmidzi Fath, Citra F Theodorea, Natalina Haerani, Yuniarti Soeroso, Selvi Nafisa Shahab, Ardy Wildan, Fergie Marie Joe Grizella Runtu, Fatimah Maria Tadjoedin, Dewi Ayuningtyas, Lisa Amir, Endang W Bachtiar","doi":"10.3389/fdmed.2025.1550936","DOIUrl":"https://doi.org/10.3389/fdmed.2025.1550936","url":null,"abstract":"<p><p>Oral samples are widely used for studying oral microbiome in health and diseases. In this study, saliva and subgingival biofilm (SGB) samples obtained from patients with type2 diabetes (T2DM), without periodontitis (G1 group), with gingivitis (G2 group), and periodontitis (G3 group), were used to compare the abundance of <i>Saccharibacteria</i> (TM7), its host's bacteria (<i>Schaalia odontolytica</i>), periodontopathogen (Represented by <i>Fusobacterium nucleatum</i>), and nitrate-reducing bacteria (represented by <i>Rothia mucilaginosa</i>). The gingival crevicular fluid were also used to analyze the transcription levels of interleukin-6 (IL-6) and C-reactive protein (CRP). Healthy individuals' oral samples served as a control, and the targeted bacteria and inflammatory indicators were detected and measured using real-time PCR. The results showed that in either sample, the abundance of TM7 and other targeted bacteria showed a similar profile. Notably, within participants with T2DM, the abundance of TM7 was similar in G1 and G2 groups, but significantly decreased in G3 group. With the exception of the SGB of the G3 group, the relationship between TM7 and its bacterial host was strongly positive across all evaluated samples. Furthermore, CRP had higher transcription levels than IL-6 across the entire group. Despite the fact that the G3 group showed an adverse relationship between TM7 and CRP, patients with T2DM generally showed a positive correlation between TM7 and IL-6/CRP, which was verified by a receiver operating curve.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1550936"},"PeriodicalIF":1.5,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12053271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the 4D printing linked bio-smart materials in dentistry: a concise overview.","authors":"Maajida Aafreen M, Priyanka K Cholan, Paavai Ilango, Harinath Parthasarathy, Anupama Tadepalli, Lakshmi Ramachandran","doi":"10.3389/fdmed.2025.1558382","DOIUrl":"https://doi.org/10.3389/fdmed.2025.1558382","url":null,"abstract":"<p><p>4D printing advances traditional 3D printing by incorporating the dimension of time, enabling stimuli-responsive shape or behavior changes. Bio-smart materials, crucial to this technology, enable programmable transformations with significant potential in biomechanics and dentistry. This review explores the use of smart materials and stimuli in 4D printing, emphasizing dental applications.A comprehensive search across EMBASE, Web of Science, MEDLINE, Cochrane Library and clinical trial registries identified 154 articles on 4D printing technologies, biomaterials, and stimuli relevant to dental applications. Of these, 84 were pertinent to the review's objective, with 25 specifically focused on 4D printing and various smart materials. The review highlights biomaterials engineered for programmable responses, such as shape memory polymers, shape memory elastomers, responsive inks, and hydrogels. These materials enable the creation of structures that can adapt, self-assemble, or respond to stimuli like temperature, moisture, or pH levels. In dentistry, these capabilities show potential for applications in orthodontics, implants, and tissue engineering.The integration of 4D printing and bio-smart materials has the potential to transform dentistry by creating adaptive, time-responsive structures. This technology enables personalized, precise, and minimally invasive treatments, addressing complex biomechanical challenges in dental care.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1558382"},"PeriodicalIF":1.5,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of artificial neural network model for predicting the rapid maxillary expansion technique in children with cleft lip and palate.","authors":"Mohamed Zahoor Ul Huqh, Johari Yap Abdullah, Adam Husein, Matheel Al-Rawas, Wan Muhamad Amir W Ahmad, Nafij Bin Jamayet, Mohammad Khursheed Alam, Mohd Rosli Bin Yahya, Siddharthan Selvaraj, Abedelmalek Kalefh Tabnjh","doi":"10.3389/fdmed.2025.1530372","DOIUrl":"https://doi.org/10.3389/fdmed.2025.1530372","url":null,"abstract":"<p><strong>Aim: </strong>The study aimed to determine the mid-palatal suture (MPS) maturation stages and to develop a binary logistic regression model to predict the possibility of surgical or non-surgical rapid maxillary expansion (RME) in children with unilateral cleft lip and palate (UCLP).</p><p><strong>Methods: </strong>A retrospective case control study was conducted. A total of 100 subjects were included. Data was gathered from the databases of Hospital Universiti Sains Malaysia and Hospital Raja Perempuan Zainab II, respectively. Cone beam computed tomography scans of both cleft and non-cleft individuals were utilized to determine the MPS maturation stages. Romexis software version 3.8.2 was used to analyze the images.</p><p><strong>Results: </strong>The results of the binary logistic regression model were utilized to establish the relationship between the probability (P) of a specific event of interest (P(Y = 1)) and a linear combination of independent variables (Xs) using the logit link function. Potential factors such as age, gender, cleft, category of malocclusion, and MPS were chosen which could play a role in predicting the technique of RME in children with UCLP and non-UCLP. A subset of these variables was validated via multilayer feed forward neural network (MLFFNN).</p><p><strong>Conclusions: </strong>The effectiveness of the hybrid biometric model created in this work, which combines bootstrap and BLR with R-syntax was evaluated in terms of how accurately it predicted a binary response variable. A validation method based on an MLFFNN was used to evaluate the precision of the generated model. This leads to a good outcome.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1530372"},"PeriodicalIF":1.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}