Frontiers in dental medicine最新文献

{"title":"Effect of polydopamine on bonding characteristics and color stability of blood contaminated Biodentine to composite.","authors":"Ihtisam Alam, Aravind R Kudva, S Vidhyadhara Shetty, Jayprakash Kukkila","doi":"10.3389/fdmed.2026.1945910","DOIUrl":"10.3389/fdmed.2026.1945910","url":null,"abstract":"<p><strong>Introduction: </strong>Calcium silicate cements such as Biodentine are frequently placed in a blood-contaminated field during vital pulp therapy and must subsequently be bonded to an overlying resin composite. Polydopamine (PDA) improves the wettability and bond strength of mineral trioxide aggregate to resin composite, but its effect on blood-contaminated Biodentine is unknown.</p><p><strong>Aim: </strong>To determine the effect of PDA pretreatment on the shear bond strength (SBS), failure mode and colour change (<i>Δ</i>E) of blood-contaminated and uncontaminated Biodentine bonded to resin composite.</p><p><strong>Materials and methods: </strong>Seventy-six standardised Biodentine specimens (5 mm diameter × 3 mm) were prepared with blood contamination (present/absent) and PDA pretreatment (present/absent) as the two factors (<i>n</i> = 19 per cell). After adhesive application, bulk-fill composite build-up and 45 days of storage at 37 °C, SBS was measured, failure modes and <i>Δ</i>E was analysed.</p><p><strong>Results: </strong>Blood contamination significantly reduced SBS [F(1,72) = 18.86, <i>P</i> < 0.001, partial <i>η</i> ² = 0.21] and the contamination × PDA interaction was significant [F(1,72) = 7.39, <i>P</i> = 0.008, partial <i>η</i> ² = 0.09], whereas the main effect of PDA was not [F(1,72) = 2.07, <i>P</i> = 0.155]. Simple-effect analysis showed that PDA increased SBS in contaminated specimens (6.44 → 7.77 MPa; mean difference 1.33 MPa, 95% CI 0.43-2.23; <i>P</i> = 0.004) but not in uncontaminated specimens (8.70 → 8.29 MPa; <i>P</i> = 0.368). Without PDA, contamination lowered SBS by 2.26 MPa (<i>P</i> < 0.001), whereas after PDA pretreatment the difference between contaminated and uncontaminated specimens was no longer significant (<i>P</i> = 0.254). Contamination significantly increased <i>Δ</i>E (<i>P</i> < 0.001) whereas PDA did not (<i>P</i> = 0.102); all groups exceeded the clinical acceptability threshold. Failure-mode distribution differed significantly among groups (Fisher-Freeman-Halton exact <i>P</i> = 0.021; Cramér's V = 0.30), cohesive failure within Biodentine predominating in the contaminated groups.</p><p><strong>Conclusions: </strong>Within the limitations of this <i>in vitro</i> study, blood contamination occurring during setting reduced the shear bond strength of Biodentine to resin composite and increased its discolouration. PDA pretreatment significantly improved bond strength in contaminated specimens only, abolishing the statistically significant contamination penalty, and did so without aggravating colour change.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1945910"},"PeriodicalIF":2.7,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13612303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Faculty development and institutional readiness for incorporating AI in health professions education-a narrative review.","authors":"Prathibha Prasad, Mahinour Amin, Elizabeth Fitriana Sari, Lovely M Annamma, Jayaraj Narayanan, Dinesh Yasothkumar, Mehzabin Ahmed","doi":"10.3389/fdmed.2026.1986847","DOIUrl":"10.3389/fdmed.2026.1986847","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/fdmed.2026.1874590.].</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1986847"},"PeriodicalIF":2.7,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13614096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149065999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Explainable artificial intelligence in dental imaging: a systematic review of interpretability and the current state of trust evidence.","authors":"Wlla E Al-Hammad, Mohammad Y Khatatbeh, Ghaida AlJamal, Mohammed Q Shatnawi, Bara'a Fawaeer, Salem Alhatamleh, Abdel Rahman F Shawaqfeh, Haron El-Rasheed Nijim, Muneer A Al-Refai, Ahmad F Hindawi, Anas Odat, Shams Eldin M Saleh, Abdel Rahman M Alzoubi, Khaled W Tashtoush, Ahmad M Alkhamaiseh, Loay E Al-Hammad","doi":"10.3389/fdmed.2026.1948676","DOIUrl":"10.3389/fdmed.2026.1948676","url":null,"abstract":"<p><p>Explainable artificial intelligence (XAI) is increasingly used to improve the transparency of artificial intelligence models in dental and maxillofacial imaging, but the rigor with which explanations are evaluated remains unclear. This systematic review identified and categorized XAI approaches, their evaluation methods, and reported outcomes related to clinician trust and usability. The review was conducted in accordance with the PRISMA 2020 statement. Six electronic sources were searched, supplemented by Google Scholar and reference-list screening. Data were extracted on imaging modality, clinical application, explanation method, explanation scope, relationship to the predictive model, output format, evaluation approach, trust- or usability-related outcomes and external validation status. Risk of bias and applicability were assessed using QUADAS-2 and PROBAST. In total, 61 papers that met the specified inclusion criteria were identified. CAM-based local explanations predominated, whereas formal assessment of faithfulness, clinician trust, and usability was uncommon. Most included studies were judged to have a high overall risk of bias. Current evidence describes the technical use of XAI more strongly than its clinical utility. Future studies should use prespecified explanation taxonomies, quantitative faithfulness and localization tests, and clinician-centered evaluations of decision performance and calibrated reliance.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/PROSPERO/view/CRD420261421868.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1948676"},"PeriodicalIF":2.7,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13612324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149066333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and quantification of <i>Enterococcus faecalis</i> by real-time quantitative pcr during endodontic treatment.","authors":"Shruthi H Attavar, Rochi Kapoor, Suvarna Kavya Harish, Veena Shetty, Shriya Shetty","doi":"10.3389/fdmed.2026.1907257","DOIUrl":"10.3389/fdmed.2026.1907257","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the quantification of <i>Enterococcus faecalis</i> using quantitative polymerase chain reaction (qPCR) and culture techniques following different root canal irrigation protocols in refractory endodontic cases.</p><p><strong>Materials and methods: </strong>Fifty refractory endodontic cases were randomly allocated into five experimental groups according to the irrigant and activation method used: Group I, saline irrigation; Group II, 5.25% sodium hypochlorite with Passive ultrasonic irrigation; Group III, 5.25% sodium hypochlorite with EndoActivator; Group IV, 2% chlorhexidine with Passive ultrasonic irrigation; and Group V, 2% chlorhexidine with EndoActivator. Microbiological samples were collected before and after disinfection using sterile paper points. Quantification of <i>Enterococcus faecalis</i> was performed using conventional culture techniques and qPCR. Data were analyzed using one-way ANOVA, <i>post hoc</i> Tukey test, and paired t-tests (<i>P</i> < 0.05).</p><p><strong>Results: </strong>Post-treatment bacterial counts were significantly lower in all experimental groups than in the saline control (<i>P</i> < 0.001). Group II (NaOCl with Passive ultrasonic irrigation) showed the greatest reduction, with mean post-treatment counts of 1.73 × 10⁵ CFU/mL by culture and a mean log CFU of 3.56 by qPCR, compared with 408 × 10⁵ CFU/mL and 26.54 log CFU, respectively, in the saline control. Both culture and qPCR demonstrated significant reductions in <i>E. faecalis</i> following all active irrigation protocols, with Group II consistently showing the greatest reduction across both detection methods.</p><p><strong>Conclusion: </strong>5.25% NaOCl activated by Passive ultrasonic irrigation achieved the greatest reduction in <i>E. faecalis</i> across both culture and qPCR assessments.</p><p><strong>Clinical significance: </strong>Passive ultrasonic activation of sodium hypochlorite may enhance root canal disinfection by significantly reducing <i>Enterococcus faecalis</i>, a microorganism commonly associated with persistent endodontic infections. The use of qPCR provides a sensitive method for evaluating the antimicrobial efficacy of endodontic irrigation protocols.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1907257"},"PeriodicalIF":2.7,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149032073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clear aligner therapy among orthodontists in Turkey: practice patterns and comparison with previously reported Iranian findings.","authors":"Ali Borzabadi-Farahani, Hatice Kübra Olkun, Mohammad Behnaz","doi":"10.3389/fdmed.2026.1896311","DOIUrl":"10.3389/fdmed.2026.1896311","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this paper is to investigate clear aligner therapy (CAT) practice patterns among Turkish orthodontists and compare them with Iranian specialist orthodontists.</p><p><strong>Methods: </strong>A web-based cross-sectional survey of Turkish specialist orthodontists assessed CAT use, adjuncts, training, case selection by malocclusion and age, monitoring and retention protocols, and perceived advantages/disadvantages. Findings were compared with a previously published survey of 142 Iranian orthodontists.</p><p><strong>Results: </strong>A total of 178 Turkish orthodontists participated (7.5% response rate; 71 males, 107 females). Most were aged 30-39 years (53.9%), had 11-20 years of experience (42.1%), and worked in private practice (62.9%). CAT use was reported by 96.1% of Turkish orthodontists versus 69.0% of Iranian orthodontists. More Turkish orthodontists initiated >50 new CAT cases annually (33.1% vs. 7.7%), while fewer reported <10 cases/year (18.0% vs. 35.9%). CAT use was significantly higher in Turkey across all age groups (<i>P</i> < 0.001). Preferences were similar for mild crowding, spacing, and anterior cross-bite. Turkish orthodontists more frequently used CAT for complex cases, including mild/moderate open bite and severe crowding (<i>P</i> < 0.05). CAT was preferred more for limited extraction and space-opening cases than orthognathic surgery cases. Iranian orthodontists more commonly used local manufacturers (49.3% vs. 15.7%) and in-office aligner production (19% vs. 9%). Perceptions regarding CAT advantages and limitations were largely similar between groups.</p><p><strong>Conclusion: </strong>Among respondents, CAT was more widely integrated into orthodontic practice in Turkey, with broader self-reported clinical indications and more positive clinician perceptions than in Iran. Iranian orthodontists relied more on locally manufactured and in-office aligners.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1896311"},"PeriodicalIF":2.7,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13597842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149042433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance of artificial intelligence in oral squamous cell carcinoma detection: a higher-order evidence synthesis through umbrella review and meta-meta-analysis.","authors":"Praveen Jodalli, Vineet Vinay, Mahesh Chavan, Ramya Shenoy, Utkarsha Deshpande, Sam Thomas Kuriadom, Apurva Mishra, Raghavendra M Shetty","doi":"10.3389/fdmed.2026.1915105","DOIUrl":"10.3389/fdmed.2026.1915105","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The integration of AI into oral squamous cell carcinoma (OSCC) diagnostics is a major milestone for digital dentistry and computational pathology, enabling faster, highly accurate detection. While numerous systematic reviews have attempted to synthesize this burgeoning evidence, their conclusions remain discordant and methodological quality varies substantially.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;This umbrella review undertakes a rigorous synthesis of systematic review evidence to establish definitive accuracy metrics, evaluate methodological robustness, quantify evidence redundancy, and delineate critical implementation barriers.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A comprehensive search was conducted across MEDLINE/PubMed, Embase, Scopus, Web of Science, and Cochrane CENTRAL from inception through September 30, 2025, following PRISMA guidelines and an &lt;i&gt;a priori&lt;/i&gt; PROSPERO-registered protocol (CRD420251157762). Systematic reviews evaluating AI for OSCC diagnosis were included. Methodological quality was appraised using AMSTAR-2, while primary study overlap was quantified via Corrected Covered Area (CCA). A meta-meta-analysis employing robust variance estimation was performed to pool diagnostic accuracy measures, accounting for statistical dependency.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Fifteen systematic reviews synthesizing 341 primary studies were included. AMSTAR-2 assessment revealed a concerning distribution: only 3 reviews (20%) achieved high confidence, while 3 (20%) were critically low. Moderate primary study overlap was evident (CCA = 9.06%). The meta-meta-analysis, incorporating data from six reviews, yielded a pooled sensitivity of 0.90 (95% CI: 0.81-0.99; I&lt;sup&gt;2&lt;/sup&gt; = 85%; &lt;i&gt;τ&lt;/i&gt; &lt;sup&gt;2&lt;/sup&gt; = 0.032). The 95% confidence interval suggested that the diagnostic performance of AI may vary substantially in future comparable reviews, reflecting differences in AI models, imaging modalities, study populations, and methodological approaches. Although the pooled estimate indicates high overall sensitivity, the wide confidence and prediction intervals indicate uncertainty regarding the magnitude and consistency of the effect, suggesting that AI performance may not be uniformly reproducible across different clinical settings.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;AI demonstrated compelling diagnostic accuracy for OSCC, particularly when applied to histopathological specimens. However, the evidence base is compromised by significant heterogeneity, methodological inconsistency, and a critical deficit in implementation research. This synthesis provided an authoritative evidence foundation and a strategic roadmap for researchers, clinicians, and policymakers navigating the evolving landscape of AI in oral oncology.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical relevance: &lt;/strong&gt;The integration of AI into routine clinical practice may assist clinicians in identifying suspicious lesions at earlier stages, improving diagnostic consistency, reducing","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1915105"},"PeriodicalIF":2.7,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13593500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149026735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontitis and Alzheimer's disease, common pathways in down syndrome.","authors":"Fabio Arriola-Pacheco, Alicia Leonor Pinzón-Té, Rodrigo Serrano-Piña, Bertha Arelly Carrillo-Ávila, Jaime Díaz-Zúñiga, Samanta Melgar-Rodríguez, Víctor Manuel Martínez-Aguilar","doi":"10.3389/fdmed.2026.1930049","DOIUrl":"10.3389/fdmed.2026.1930049","url":null,"abstract":"<p><p>Down Syndrome (DS) involves widespread systemic issues, including a near-universal development of early-onset Alzheimer's Disease, driven by factors beyond Amyloid Precursor Protein (APP) over-expression, such as chronic neuroinflammation and endosomal dysfunction. High prevalence of periodontitis in this population acts as a significant source of peripheral inflammation that may accelerate this cognitive decline, necessitating further study into the bidirectional, pro-inflammatory links between systemic health and neurodegeneration in DS. This review analyzes the common pathophysiological pathways linking periodontitis and AD development within the DS population, evaluating how oral dysbiosis acts as a systemic driver of neurodegeneration. We synthesized current molecular, microbiological, and clinical evidence evaluating the bidirectional relationships between trisomy 21-induced immune dysfunction, severe periodontitis, and accelerated cognitive decline. Individuals with DS exhibit a heightened susceptibility to aggressive, early-onset periodontitis starting as early as age six. This chronic oral dysbiosis facilitates microbial translocation, allowing periodontal pathogens (e.g., <i>Porphyromonas gingivalis</i>) and their virulence factors to cross the blood-brain barrier via circulatory or trigeminal routes. In the central nervous system, these pathogens encounter microglial populations already genetically primed by trisomy 21. This induces an exacerbated M1 microglial phenotype response, triggering sustained neuroinflammation, defensive over-deposition of Amyloid-β (Aβ) plaques, and upregulation of GSK-3β, which accelerates Tau protein hyperphosphorylation. While bidirectional links are strongly indicated, current literature lacks robust longitudinal studies connecting periodontal, microbiological, and cognitive data to establish definitive causality. Early clinical intervention and management of gum disease present a critical therapeutic window to delay the onset and slow the progression of AD in this vulnerable population.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1930049"},"PeriodicalIF":2.7,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13591152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149018776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A narrative discussion on the impact of respiratory infectious diseases on dental education in China: implications for curriculum design and student outcomes.","authors":"Shuhao Xu, Xiaolong Li, Wei Li, Ruijie Huang","doi":"10.3389/fdmed.2026.1897947","DOIUrl":"10.3389/fdmed.2026.1897947","url":null,"abstract":"<p><strong>Objective: </strong>Recent outbreaks of respiratory infectious diseases, transmitted via aerosols, have placed dental healthcare workers at high risk. Traditional dental education, based on student-teacher-patient interactions, faces unprecedented challenges across all stages. From admissions to classroom teaching, laboratory instruction, clinical training, and final examinations, every aspect of dental education is undergoing significant challenges and is in urgent need of change.</p><p><strong>Methods: </strong>This narrative review with content analysis synthesized literature on the impact of respiratory infections on dental education. We systematically searched PubMed, Web of Science, and CNKI (2020-2026) using relevant keywords. Two reviewers independently screened and selected studies. Data were thematically analyzed into five core domains: classroom teaching, laboratory teaching, clinical teaching, student admissions/assessment, and licensing examinations.</p><p><strong>Results: </strong>In classroom teaching, online platforms and AI-augmented PBL/CBL were rapidly adopted, yet persistent issues included network instability, limited interaction, digital inequities, and heavy reliance on student self-discipline. In laboratory teaching, AR/VR and iLab-X enabled remote training, but were constrained by high costs, poor haptic realism, inability to replicate patient emotions, and equipment dependence. In clinical teaching, enhanced infection controls-including PPE, rubber dams, and HEPA filtration-were implemented, though bio-aerosol risks, reduced patient flow, and limited clinical exposure remained. In admissions, online exams with dual-camera proctoring, open-ended questions, AI-generated items, and virtual OSCEs were adopted, while challenges persisted in cheating prevention, subjective scoring, validity, and privacy. Licensing examinations remained in-person with strict protection; VSP showed promise but lacked robust evidence and incurred high costs. Overall, technological innovations enabled educational continuity, yet significant infrastructure gaps, inequities, and unresolved validity issues persist across all domains.</p><p><strong>Conclusion: </strong>China's dental education rapidly adapted to respiratory epidemics through online teaching, simulation, and enhanced infection control, yet persistent challenges remain in digital equity, cost, validity, and infrastructure. These innovations are important primarily because they directly influence student learning outcomes-including knowledge acquisition, clinical reasoning, and skill retention-while also shaping curriculum design. Future preparedness requires sustained investment, faculty development, equitable access, and rigorous longitudinal research to validate skill transfer to clinical practice, ensuring that technological advances ultimately translate into measurable improvements in student competency and patient safety.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1897947"},"PeriodicalIF":2.7,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149009271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: Dental treatment under general anesthesia for a child with Ullrich congenital muscular dystrophy.","authors":"SokIok Cheang, WeiYun Chen, Shuang Wang, XinXin Wang, Kuo Wan, Lin Ma","doi":"10.3389/fdmed.2026.1881573","DOIUrl":"10.3389/fdmed.2026.1881573","url":null,"abstract":"<p><strong>Background: </strong>Ullrich congenital muscular dystrophy (UCMD) is a rare inherited myopathy caused by mutations in the COL6 gene and is frequently associated with multisystem complications affecting the respiratory and skeletal systems, which may increase airway and anesthetic risks during dental treatment.</p><p><strong>Case report: </strong>This report describes a 4-year-old girl with UCMD who presented with pain in the left lower molar. After a comprehensive multidisciplinary evaluation by the Department of Stomatology, Anesthesiology, and Pediatrics, the patient was classified as ASA III and underwent dental treatment under total intravenous anesthesia, with tracheal intubation performed under fiberoptic bronchoscopic guidance. The procedures included pulpotomy, tooth extraction, resin restoration, placement of preformed metal crowns, and topical fluoride application. The perioperative course was uneventful and no respiratory, airway, or anesthesia-related adverse events were observed. The patient was followed up continuously for 6 to 12 months after dental treatment.</p><p><strong>Conclusion: </strong>This report delineates the multidisciplinary perioperative management of comprehensive dental treatment in a 4-year-old patient with UCMD, thereby providing a clinical reference for oral healthcare in individuals with this rare disorder.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1881573"},"PeriodicalIF":2.7,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13581768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148992874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and perioperative outcomes of computer-guided versus conventional plan-transfer workflows in orthognathic surgery for skeletal anterior open bite: a randomized controlled trial.","authors":"Ammar Abu Shama, Dirar Dibs","doi":"10.3389/fdmed.2026.1923688","DOIUrl":"10.3389/fdmed.2026.1923688","url":null,"abstract":"<p><strong>Introduction: </strong>Skeletal anterior open bite (AOB) often requires orthognathic surgery. This study compared the clinical and perioperative outcomes of computer-guided and conventional plan-transfer workflows following virtual surgical planning.</p><p><strong>Methods: </strong>Eighteen adults with skeletal AOB underwent virtual surgical planning and were subsequently randomized to computer-guided transfer of the established surgical plan using CAD/CAM guides (<i>n</i> = 9) or conventional model-surgery transfer using articulator-mounted casts and occlusal wafers (<i>n</i> = 9). Outcomes included intraoperative handling, operative time, blood loss, complications, healing, and AOB correction.</p><p><strong>Results: </strong>Mean operative time was 6.0 ± 0.5 h versus 6.5 ± 0.6 h (<i>p</i> = 0.08), and blood loss was 450 ± 60 versus 520 ± 80 mL (<i>p</i> = 0.12) for the computer-guided and conventional groups, respectively. Intraoperative handling was perceived as easier with computer guidance, although this assessment was subjective. No major intraoperative complications occurred. Mean postoperative AOB was 1.33 ± 0.50 mm in both groups (<i>p</i> = 1.00).</p><p><strong>Conclusion: </strong>No statistically significant between-group differences were detected in operative time, blood loss, or postoperative AOB. Computer-guided plan transfer was perceived to facilitate intraoperative handling, although this assessment was subjective. Given the small sample size and limited statistical power, the absence of statistically significant differences should not be interpreted as evidence of equivalence between the workflows. Larger adequately powered studies are warranted.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1923688"},"PeriodicalIF":2.7,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13581504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}