Frontiers in dental medicine最新文献

{"title":"Residual bone level as a prognostic factor in the surgical treatment of peri-implantitis.","authors":"Rodrigo Martin-Cabezas, Catherine Giannopoulou","doi":"10.3389/fdmed.2024.1532094","DOIUrl":"10.3389/fdmed.2024.1532094","url":null,"abstract":"<p><p>Peri-implantitis is a progressive inflammatory disease affecting the tissues surrounding dental implants and leading to bone loss. The severity of this disease is typically classified based on the depth of the bone defect or the percentage of bone loss around the implant. Marginal bone loss is a critical factor in the surgical management of peri-implantitis, as it can complicate access for implant decontamination and hinder efforts to stabilize the condition. In cases where bone loss exceeds 50% of the implant length, explantation is often recommended due to significantly reduced success rates after treatment. This narrative review seeks to examine the scientific evidence on marginal bone loss as a prognostic factor in the surgical treatment of peri-implantitis.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1532094"},"PeriodicalIF":1.5,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for diabetes and hypertension in adult dental patients: the experience in a Nigerian dental center.","authors":"Ukachi Chiwendu Nnawuihe, Emmauel Adetolu Adelusi, Afolake Shakirat Salami, Ezekiel Taiwo Adebayo, Lilian Ejije Ahaji","doi":"10.3389/fdmed.2024.1468375","DOIUrl":"10.3389/fdmed.2024.1468375","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of the present study was to examine the presentation of hypertension and diabetes mellitus in dental patients.</p><p><strong>Methods: </strong>Dental patients were screened for hypertension and elevated blood sugar using a sphygmomanometer and a glucometer, respectively.</p><p><strong>Results: </strong>A total of 102 men and 129 women participated in the study. In total, 69 (29.9%) and 20 (8.7%) participants reported a history of hypertension and diabetes mellitus, respectively. Adherence to taking hypertensive and diabetic medications as advised by a clinician was reported by 68.0% and 85.0% of patients with known hypertension and diabetes, respectively, of whom 29.8% had uncontrolled hypertension and 29.4% had high blood sugar in the diabetic range (>200 mg/dl). In patients with no history of these diseases, 42 (25.9%) had elevated blood pressure, while 5 (2.4%) had high blood sugar in the diabetic range. The prevalence of hypertension was 37.3% and high blood sugar in the diabetic range was 5.2% in the sample. Individuals with diabetes were 31 times more likely to have hypertension than those without diabetes (odds ratio = 31.06, 95% confidence interval 5.68-169.98, <i>p</i> ≤ 0.001).</p><p><strong>Conclusion: </strong>Screening was helpful in the detection of undiagnosed cases and suboptimal control of both diseases in patients. Recommendations for dental practice guidelines include routine screening with mandatory screening for hypertension in patients with diabetes.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1468375"},"PeriodicalIF":1.5,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MicroRNA-21-5p profile in the alveolar bone following tooth extraction in medication-related osteonecrosis of the jaw rat model.","authors":"Manta Morakotsriwan, Theerapat Chanamuangkon, Anjalee Vacharaksa, Pirawish Limlawan","doi":"10.3389/fdmed.2024.1477274","DOIUrl":"10.3389/fdmed.2024.1477274","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare microRNA-21-5p expressions at the extraction wound in the maxillary bones of rats with medication-related osteonecrosis of the jaw (MRONJ) and normal rats at different time points.</p><p><strong>Materials and methods: </strong>In total, 18 female, 8-week-old Sprague-Dawley rats were randomly assigned to the experimental group (<i>n</i> = 9) and the control group (<i>n</i> = 9). To establish MRONJ in the right maxillary first molar area in the experimental group, zoledronate (66 µg/kg) and dexamethasone (5 mg/kg) were administered intraperitoneally every other day for 2 weeks before tooth extraction. Normal saline was administered in the control group. After tooth extraction, the drugs were continuously administered until the experimental endpoints, namely 1, 14, and 28 days post-tooth extraction. At each endpoint, three rats from each group were euthanized. The maxilla bones at the wound area were harvested. A real-time polymerase chain reaction (RT-PCR) was performed to compare the expression levels of miRNA-21-5p at each time point between the MRONJ group and the control group.</p><p><strong>Results: </strong>From their gross appearance, the rats that received zoledronate and dexamethasone developed MRONJ as demonstrated by non-healing wounds and exposed bone at 14 and 28 days post-extraction in contrast to the controls. The RT-PCR showed that the expression levels of miRNA-21-5p were relatively higher in the MRONJ rats compared to the control rats at day 14 and then the difference was lower at day 28 post-tooth extraction.</p><p><strong>Conclusion: </strong>The findings indicated that the microRNA-21-5p expression levels varied during the socket healing process in the MRONJ rats, reaching a peak at 2 weeks after tooth extraction.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1477274"},"PeriodicalIF":1.5,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In vitro</i> assessment of chemical surface treatments on the shear bond strength of metal orthodontic brackets to CAD/CAM provisional materials.","authors":"Abdulaziz A Alzaid, Khalid K Alanazi, Maha N Alharbi, Lulu A Alyahya, Hatem Alqarni, Mohammed Alsaloum, Hayam Alfallaj, Ghada S Alotaibi","doi":"10.3389/fdmed.2024.1494484","DOIUrl":"10.3389/fdmed.2024.1494484","url":null,"abstract":"<p><strong>Introduction: </strong>The growing demand for orthodontic treatment in patients irrespective of age highlights the need for effective bonding of brackets to provisional crowns (PCs).</p><p><strong>Aims and objectives: </strong>This study evaluates the shear bond strength (SBS) of orthodontic brackets to 3D-printed and milled PC materials, comparing the effects of hydrofluoric acid (HFA) and phosphoric acid (PA) etching.</p><p><strong>Materials and methods: </strong>Forty cylinders were fabricated using a 3D printer with hybrid resin, and forty were milled from cross-linked polymethyl methacrylate (PMMA) resin. Stainless steel brackets were bonded with light-cured composite resin. Twenty specimens from each group were treated with 9.5% HFA, while the rest of the specimens received 37% PA. Post-bonding, specimens underwent thermocycling and were examined with SEM. SBS testing followed ISO/TS 11405-2015 guidelines. The failure patterns and bond interface were assessed by the Adhesive Remnant Index (ARI) and scanning electron microscopy (SEM). Data was analyzed using ANOVA, Tukey's test.</p><p><strong>Results: </strong>In 3D-printed materials, HFA etching yielded a significantly higher bond strength (12.59 ± 2.64 MPa) than PA etching (7.77 ± 0.83 MPa). The bond strength was inferior in milled materials: HFA (5.98 ± 0.59 MPa) and PA (5.66 ± 0.65 MPa) with no significant difference between both surface treatments. When each material was evaluated separately, a significant difference in SBS was found for surface treatments in 3D-printed materials (<i>p</i> < 0.001) but not for milled materials (<i>p</i> = 0.916). ARI scores showed greater adhesive retention in 3D-printed specimens, particularly those treated with HFA. SEM revealed smoother surfaces in 3D-printed specimens compared to rougher surfaces in milled specimens.</p><p><strong>Conclusion: </strong>HFA etching improves SBS in 3D-printed PC, while in milled materials, the choice of etching agent has minimal effect.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1494484"},"PeriodicalIF":1.5,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endodontic treatment of a two-rooted mandibular first premolar with four root canals: a case report.","authors":"Peiling Hu, Shuang Feng, Xin Li, Guangwen Li, Shiting Li","doi":"10.3389/fdmed.2024.1498167","DOIUrl":"10.3389/fdmed.2024.1498167","url":null,"abstract":"<p><strong>Background: </strong>Mandibular first premolar has a complex and variable anatomy of the root canal system, which often leads to failure of endodontic treatment due to missing root canals. Identifying the complete structure of the root canal system to ensure that all root canals are perfectly cleared and filled becomes critical to the success of root canal therapy. This report introduced a unique case of endodontic treatment of a two-rooted mandibular first premolar in the buccolingual direction with a total of four canals.</p><p><strong>Case presentation: </strong>An adult male patient with a lower left first premolar was diagnosed with acute apical periodontitis and treated with open pulp drainage in a general hospital. One day later, due to the complexity of the root canal structure, the patient was referred to our clinic for subsequent treatment. The tooth #34 was diagnosed with abnormal central cusp, apical periodontitis, and incomplete fracture through clinical and x-ray examinations. Cone-beam Computed Tomography (CBCT) results showed that the tooth #34 processed two roots with a buccolingual bifurcation and a total of 4 root canals: 1 lingual canal, 2 mesiobuccal canals, and 1 distobuccal canal. Notably, the buccal root presented a C-shaped configuration, and the mesiobuccal canals were of 2-1 type. The tooth was treated with microendodontics and crown restoration. One year after the treatment, the follow-up results showed that the tooth #34 was functioning normally without any abnormalities.</p><p><strong>Conclusion: </strong>This report enhances our understanding of the anatomical variations in the root canal system of the mandibular first premolar and emphasizes the importance of CBCT in identifying anatomical variations within the root canal system. Clinicians must be aware of such changes in the mandibular first premolar during treatment to ensure a perfect treatment and better prognosis in clinical practice.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1498167"},"PeriodicalIF":1.5,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implant-supported prosthesis under progressive loading protocol stimulates alveolar bone growth in patients with severe alveolar bone atrophy. Retrospective case series.","authors":"Eduardo Anitua, Laura Piñas, Mohammad H Alkhraisat","doi":"10.3389/fdmed.2024.1465137","DOIUrl":"10.3389/fdmed.2024.1465137","url":null,"abstract":"<p><strong>Introduction: </strong>The jaw with severe bone atrophy is a difficult challenge when rehabilitating with dental implants. To be able to place dental implants in the most severe cases and to achieve an increase in bone volume by means of the tension transmitted by the load is a novelty. This work provides data on the alveolar bone changes in a severely atrophic mandible that has been treated with implant supported prosthesis under progressive loading protocol.</p><p><strong>Material and methods: </strong>This study reported on 3 patients with completely edentulous mandible. In all cases, implants were inserted in the anterior region of the mandible and progressive loading was carried out with an increase in the distal cantilever. The length of the cantilever extension was adapted to growth of the residual alveolar bone at the mandible body. The increase in bone height was controlled in the area of implant placement as well as in the area distal to the implants (1 cm behind the last implant).</p><p><strong>Results: </strong>This case series described 3 patients where 13 implants were placed. The patients were followed for 17, 19 and 20 years after implants insertion. The mean mandibular residual height of the alveolar bone was 7.8 ± 2.7 mm at the implant site. The mean mandibular body height at 1.0 cm distal to the last implant was 7.0 ± 3.9 mm in the third quadrant and 8.1 ± 4.4 mm in the fourth quadrant. The mean height at the last follow-up was 11.0 ± 3.2 mm (±3.2) in the third quadrant and 11.20 ± 4.4 mm in the fourth quadrant.</p><p><strong>Conclusions: </strong>Implant-supported prosthesis and progressive loading have resulted in vertical bone growth in a series of patients with extreme atrophy of the mandible. The long-term follow-up indicated that bone growth is confined to the dental implants but has been extended to distant regions resulting in the thickening of the mandibular body and the creation of the absent mandibular canal.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1465137"},"PeriodicalIF":1.5,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development status of mouthguard.","authors":"Wang Biqi, Wang Xinyu","doi":"10.3389/fdmed.2024.1513223","DOIUrl":"10.3389/fdmed.2024.1513223","url":null,"abstract":"<p><p>The mouthguard plays a crucial role in preventing damage to the oral and jaw system. However, the popularity of sports mouthguards remains relatively low, and research on sports mouthguards is rather scattered. This paper primarily summarizes the characteristics of materials, production methods, protection principles, and influencing factors of mouthguards, with the aim of providing a theoretical reference for the popularization and application of mouthguards.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1513223"},"PeriodicalIF":1.5,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphology and thickness of the buccal bone wall of the maxillary central incisors in population: a CBCT study.","authors":"Yaping Song, Song Yang, Chao Wang","doi":"10.3389/fdmed.2024.1472028","DOIUrl":"10.3389/fdmed.2024.1472028","url":null,"abstract":"<p><p>The objective of this study was to measure and analyze the anatomical morphology and thickness of the buccal bone wall (BBW) of the maxillary central incisors, providing a theoretical basis for immediate implant surgery. A total of 372 maxillary central incisors were collected and classified into B and P types based on the root position and the degree of coverage of the BBW. The cases were divided into male and female groups, with 180 males and 192 females. The thickness of the BBW was measured at three measurement locations: 4 mm apical to the cementoenamel junction (CEJ), the mid-root, and the root apex. The number and proportion of various types of BBW are as follows: B1 (54, 14.52%), B2 (72, 19.35%), B3 (61, 16.40%), P1 (76, 20.43%), P2 (66, 17.74%), and P3 (43, 11.56%). In the B type group, the thickest BBW at 4 mm apical to the CEJ and the mid-root was observed in B3 (0.89 mm ± 0.09 mm, 0.56 mm ± 0.07 mm). The thickest BBW at the root apex was observed in B2 (0.46 mm ± 0.05 mm). In the P-type group, the thickest BBW at all three measurement locations was observed in P3 (1.10 mm ± 0.08 mm, 1.04 mm ± 0.11 mm, 3.59 mm ± 0.12 mm). The BBW of the maxillary central incisors in males was thicker than that in females. The conclusion drawn was that most BBW of the maxillary central incisors are thin, with a portion of the maxillary central incisors having only a thin BBW coverage at 4 mm apical to the CEJ and no significant bone wall coverage elsewhere. This Type of maxillary central incisor presents a higher risk of buccal soft and hard tissue recession and even bone fenestration after implant surgery. It is, therefore, crucial to assess the three-dimensional position of the root and measure the thickness of the BBW using Cone-beam computed tomography (CBCT).</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1472028"},"PeriodicalIF":1.5,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated machine learning for image-based detection of dental plaque on permanent teeth.","authors":"Teerachate Nantakeeratipat, Natchapon Apisaksirikul, Boonyaon Boonrojsaree, Sirapob Boonkijkullatat, Arida Simaphichet","doi":"10.3389/fdmed.2024.1507705","DOIUrl":"10.3389/fdmed.2024.1507705","url":null,"abstract":"<p><strong>Introduction: </strong>To detect dental plaque, manual assessment and plaque-disclosing dyes are commonly used. However, they are time-consuming and prone to human error. This study aims to investigate the feasibility of using Google Cloud's Vertex artificial intelligence (AI) automated machine learning (AutoML) to develop a model for detecting dental plaque levels on permanent teeth using undyed photographic images.</p><p><strong>Methods: </strong>Photographic images of both undyed and corresponding erythrosine solution-dyed upper anterior permanent teeth from 100 dental students were captured using a smartphone camera. All photos were cropped to individual tooth images. Dyed images were analyzed to classify plaque levels based on the percentage of dyed surface area: mild (<30%), moderate (30%-60%), and heavy (>60%) categories. These true labels were used as the ground truth for undyed images. Two AutoML models, a three-class model (mild, moderate, heavy plaque) and a two-class model (acceptable vs. unacceptable plaque), were developed using undyed images in Vertex AI environment. Both models were evaluated based on precision, recall, and F1-score.</p><p><strong>Results: </strong>The three-class model achieved an average precision of 0.907, with the highest precision (0.983) in the heavy plaque category. Misclassifications were more common in the mild and moderate categories. The two-class acceptable-unacceptable model demonstrated improved performance with an average precision of 0.964 and an F1-score of 0.931.</p><p><strong>Conclusion: </strong>This study demonstrated the potential of Vertex AI AutoML for non-invasive detection of dental plaque. While the two-class model showed promise for clinical use, further studies with larger datasets are recommended to enhance model generalization and real-world applicability.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1507705"},"PeriodicalIF":1.5,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scale dependent nanomechanical properties of dentin adhesive and adhesive-collagen composite.","authors":"Viraj Singh, Ranganathan Parthasarathy, Qiang Ye, Paulette Spencer, Anil Misra","doi":"10.3389/fdmed.2024.1423461","DOIUrl":"10.3389/fdmed.2024.1423461","url":null,"abstract":"<p><p>The complex micrometer construct at the interface that joins the composite material to the tooth surface in restorative dentistry is composed of the composite formed by infiltrating adhesive into demineralized dentin (collagen matrix). The overall performance of composite restorations is therefore directly linked to the properties of the polymerized adhesive and adhesive-collagen composite. Nanoindentation and nanoDMA tests are performed on model methacrylate based adhesive and collagen-adhesive composite to study their mechanical properties. The adhesive collagen composite is prepared by the infiltration of dentin adhesive into a completely demineralized bovine dentin. The obtained experimental results show that both the neat adhesive and the collagen-adhesive composite are heterogeneous materials at the spatial scales of property interrogation. It is also found that the reduced elastic modulus generally decreases with increasing indentation contact depth reaching an asymptote for both neat adhesive and collagen-adhesive composite. This reduced modulus behavior can be attributed to the increase in the indentation interaction volume. In addition, the measured frequency dependent storage and loss moduli indicate that both the neat adhesive and collagen adhesive composites are viscoelastic materials which are likely to exhibit creep deformation and rate-dependent behavior in physiological function.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1423461"},"PeriodicalIF":1.5,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}