Frontiers in dental medicine最新文献_第10页

Estimated Cumulative Incidence of Wisdom Tooth Extractions in Privately Insured US Patients 美国私人保险患者智齿拔除的估计累积发生率

Frontiers in dental medicine Pub Date : 2022-07-08 DOI: 10.3389/fdmed.2022.937165

A. Schroeder, T. Newman, S. Girod, Sepehr Hashemi, Astrid D. Häberle

引用次数: 0

The Roles of SIBLING Proteins in Dental, Periodontal and Craniofacial Development SIBLING蛋白在牙齿、牙周和颅面发育中的作用

Frontiers in dental medicine Pub Date : 2022-06-24 DOI: 10.3389/fdmed.2022.898802

C. Figueredo, Nancy Abdelhay, M. P. Gibson

{"title":"The Roles of SIBLING Proteins in Dental, Periodontal and Craniofacial Development","authors":"C. Figueredo, Nancy Abdelhay, M. P. Gibson","doi":"10.3389/fdmed.2022.898802","DOIUrl":"https://doi.org/10.3389/fdmed.2022.898802","url":null,"abstract":"The majority of dental, periodontal, and craniofacial tissues are derived from the neural crest cells and ectoderm. Neural crest stem cells are pluripotent, capable of differentiating into a variety of cells. These cells can include osteoblasts, odontoblasts, cementoblasts, chondroblasts, and fibroblasts which are responsible for forming some of the tissues of the oral and craniofacial complex. The hard tissue forming cells deposit a matrix composed of collagen and non-collagenous proteins (NCPs) that later undergoes mineralization. The NCPs play a role in the mineralization of collagen. One such category of NCPs is the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. This family is composed of dentin sialophosphosprotein (DSPP), osteopontin (OPN), dentin matrix protein 1 (DMP1), bone sialoprotein (BSP), and matrix extracellular phosphoglycoprotein (MEPE). The SIBLING family is known to have regulatory effects in the mineralization process of collagen fibers and the maturation of hydroxyapatite crystals. It is well established that SIBLING proteins have critical roles in tooth development. Recent literature has described the expression and role of SIBLING proteins in other areas of the oral and craniofacial complex as well. The objective of the present literature review is to summarize and discuss the different roles the SIBLING proteins play in the development of dental, periodontal, and craniofacial tissues.","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49521345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Scoping Review of Internationalization of Dental Education—Identifying Formats and Motivations in Dental Education 口腔教育国际化研究综述——识别口腔教育的模式与动因

Frontiers in dental medicine Pub Date : 2022-06-23 DOI: 10.3389/fdmed.2022.847417

Anette Wu, Abrar Shamim, Zacharie Rahhal, Monica Kieff, E. Lalla, L. Torre, Laureen A Zubiaurre Bitzer, C. Kunzel

{"title":"A Scoping Review of Internationalization of Dental Education—Identifying Formats and Motivations in Dental Education","authors":"Anette Wu, Abrar Shamim, Zacharie Rahhal, Monica Kieff, E. Lalla, L. Torre, Laureen A Zubiaurre Bitzer, C. Kunzel","doi":"10.3389/fdmed.2022.847417","DOIUrl":"https://doi.org/10.3389/fdmed.2022.847417","url":null,"abstract":"Background Internationalization efforts, including global health activities, in dental education can play an important role in preparing future oral healthcare professionals. To date, in the available literature, there is no common understanding of what internationalization of dental education might mean, and there are no agreed upon standards relating to, or a common definition of the term internationalization of dental education. Here, the authors investigate what has been published in the above area from 01/01/2000 to 12/31/2020, identifying perceived motivations and formats. A proposed definition and connection to the field of international higher education is provided. Methods A scoping review of published literature was performed and identified 47 relevant articles. The articles were thematically sorted based on educational formats and concepts (previously established in international higher education) and motivations. Results Despite the paucity of articles directly addressing internationalization of dental education, there was a large variety of articles on topics that were identified to correlate with international higher education, ranging from international partnerships, student mobility, and language, to international curriculum at home—with different perceived motivations, including competition, international understanding, and social transformation. Discussion More research on internationalization of dental education is needed to provide guidelines and formalize standards for international educational goals to better align formats and motivations for international efforts in dental education.","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49540731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of Orthodontic Appliances on the Oral Environment and Microbiome 正畸矫治器对口腔环境和微生物组的影响

Frontiers in dental medicine Pub Date : 2022-06-21 DOI: 10.3389/fdmed.2022.924835

Priti Mulimani, T. Popowics

{"title":"Effect of Orthodontic Appliances on the Oral Environment and Microbiome","authors":"Priti Mulimani, T. Popowics","doi":"10.3389/fdmed.2022.924835","DOIUrl":"https://doi.org/10.3389/fdmed.2022.924835","url":null,"abstract":"Orthodontic treatment is an appliance-intensive endeavor, where an array of mechanical devices is used to bring about tooth movement. By virtue of remaining in close proximity to the enamel, gingiva and periodontal ligament intra-orally over a prolonged period of time, orthodontic appliances have a significant impact on the paradental tissues, oral environment and oral microbiome. Orthodontic appliances by acting as anchors for biofilm and plaque formation, accumulate bacteria and other micro-organisms in amounts unfavorable for maintenance of healthy equilibrium. The resulting loss of balance in the oral microbiome causes dysbiosis which manifests clinically as increased enamel demineralization, dental caries and periodontal disease. Mechanical removal of the accumulated plaque by maintaining rigorous oral hygiene has been proven to be the single most important factor to mitigate the harmful effects of dysbiosis. This review investigates how each of the various components of the orthodontic appliances, different types of appliances and unique surface properties of biomaterials have contributory effects at the interface of orthodontic biomaterials and oral biology. The information thus obtained will be critical in instituting the best diagnostic and therapeutic measures at the clinical level. It will also be instrumental in devising improvements and providing new directions for future research in general and precision orthodontics in particular.","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44257771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Development and Testing of an Interpretational Bias Measure of Dental Anxiety 牙科焦虑的解释偏差测量方法的开发与检验

Frontiers in dental medicine Pub Date : 2022-06-17 DOI: 10.3389/fdmed.2022.871039

L. Heaton, Brian LeRoux, D. Ramsay

{"title":"Development and Testing of an Interpretational Bias Measure of Dental Anxiety","authors":"L. Heaton, Brian LeRoux, D. Ramsay","doi":"10.3389/fdmed.2022.871039","DOIUrl":"https://doi.org/10.3389/fdmed.2022.871039","url":null,"abstract":"Objectives We hypothesized that individuals with dental care-related anxiety and fear would interpret ambiguous dental situations more negatively than non-anxious individuals. The objectives of these studies were to develop and test a Measure of Dental Anxiety Interpretational Bias (MoDAIB). Methods In the development phase, participants completing an online survey provided qualitative and quantitative assessments of dental scenarios that could be interpreted in either positive or negative ways. Scenarios producing the greatest difference in visual analog (VAS) scores between individuals with high vs. low dental anxiety as measured by the Modified Dental Anxiety Scale (MDAS) were included in the MoDAIB. In the testing phase, participants completed an online survey including the newly developed MoDAIB and dental anxiety measures. Results In the development phase, participants (N = 355; 65.6% female) high in dental anxiety (MDAS ≥ 19) gave significantly higher (i.e., more negative) VAS scores to all the dental scenarios than did those low in dental anxiety (p's < 0.05). In the testing phase, the MoDAIB was significantly and positively correlated with the MDAS (r = 0.68, p < 0.001), meaning that those who were high in dental anxiety selected negative interpretations of ambiguous dental scenarios significantly more often than did individuals low in dental anxiety (p's <0.05). The MoDAIB showed good content validity and test-retest reliability. Conclusions Individuals high in dental anxiety interpret ambiguous dental situations more negatively than do less anxious individuals. Understanding individuals' interpretational styles may help dental providers avoid miscommunications. Interventions that train dentally anxious patients to consider more positive interpretations may reduce dental anxiety and should be investigated.","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43100872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: Contemporary Views on the Genetics of Dental and Craniofacial Anomalies 社论：牙齿和颅面异常遗传学的当代观点

Frontiers in dental medicine Pub Date : 2022-06-17 DOI: 10.3389/fdmed.2022.953256

T. Porntaveetus, Mushriq F Abid, M. Seppala

{"title":"Editorial: Contemporary Views on the Genetics of Dental and Craniofacial Anomalies","authors":"T. Porntaveetus, Mushriq F Abid, M. Seppala","doi":"10.3389/fdmed.2022.953256","DOIUrl":"https://doi.org/10.3389/fdmed.2022.953256","url":null,"abstract":"GJA1 (ODDD) A Report” presented a detailed case report of a patient with clinical features of both HSS and ODDD and conﬁrmed its deﬁnitive diagnosis using whole-exome sequencing (WES) and Sanger sequencing (Jimenez-Armijo et al.). Proband presented with obstructive sleep apnea, hypotrichosis, micropthalmia, hypertelorism, low convex nasal ridge, mandibular retrognathia, brachydactyly and ﬁfth ﬁnger clinodactyly, and multiple dental anomalies including brittle and brownish-yellow color deciduous teeth, thin and conoid deciduous canines, short roots, large pulps and history of caries, abscesses and multiple extractions of teeth. Although clinical features were previously associated with HSS, exome sequencing revealed novel homozygous missense variant in the Gap Junction protein Alpha ( GJA) 1 gene that has been identiﬁed as causative gene for ODDD. The variant (c.561C > G p.Cys187Trp) aﬀected the second extracellular loop of the CX43 protein and this deleterious variant was classiﬁed as likely pathogenic (Jimenez-Armijo et al.). The study supports the possibility that autosomal recessively inherited HSS/ODDD may be a single syndrome with overlapping clinical features caused by homozygous variants in speciﬁc location of the GJA1 gene sequence. It also demonstrates how problematic phenotype-based diagnosis can be especially in cases like HSS where the molecular basis is unknown and therefore highlights the beneﬁts of genetic screening in helping with early disease diagnosis that eﬀective preventative measures that are for instance","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43462616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: Remineralization Procedures in Pediatric Dentistry 社论：小儿牙科的再矿化程序

Frontiers in dental medicine Pub Date : 2022-06-14 DOI: 10.3389/fdmed.2022.949367

M. Koruyucu, Elif Bahar Tuna İnce, A. Zandoná, Adriana Modesto Vieira

{"title":"Editorial: Remineralization Procedures in Pediatric Dentistry","authors":"M. Koruyucu, Elif Bahar Tuna İnce, A. Zandoná, Adriana Modesto Vieira","doi":"10.3389/fdmed.2022.949367","DOIUrl":"https://doi.org/10.3389/fdmed.2022.949367","url":null,"abstract":"Dental caries is the most common chronic and multifactorial disease caused by the disruption of the ecological balance of the oral microbiome in the mouth mediated by diet. If the pH drops below the critical pH (pH = 5.5) as a result of the acidic environment formed in the mouth, it can lead to the dissolution of the impure hydroxyapatite structures and hard tissues in the tooth, a process called demineralization (1). The concentrations of calcium and phosphate in saliva have significant influence on the protective mechanisms of dental hard tissues within the oral environment which means also a lower critical pH. Critical pH is a dynamic metric directly dependent on salivary calcium and phosphate levels. On the other hand, remineralization is the process of returning minerals from the surrounding environment such as saliva and biofilm to the demineralized tooth structures. It can be the result of a natural process or by increasing the availability of minerals thru preventive modalities such as fluoride applications (2). The mechanisms by which the demineralization-remineralization process takes place in teeth and new methods that prevent and/or reverse demineralization or increase remineralization have been meticulously researched. Recent developments in material sciences and tissue engineering offer considerable potential to dental therapies. Transforming these new technologies into products and applications is critical to improving and developing healthcare worldwide (3). There is a wide range of remineralizing agents (4, 5).","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48567968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: Insights in Regenerative Dentistry: 2021 社论:再生牙科的见解:2021

Frontiers in dental medicine Pub Date : 2022-06-09 DOI: 10.3389/fdmed.2022.940539

P. Sharpe

引用次数: 0

Immunomodulation—What to Modulate and Why? Potential Immune Targets 免疫调节——调节什么以及为什么？潜在免疫目标

Frontiers in dental medicine Pub Date : 2022-06-03 DOI: 10.3389/fdmed.2022.883342

S. Quach, A. Zhu, R. Lee, G. Seymour

引用次数: 2

Current Status and Future Perspectives of In-office Tooth Bleaching 办公室牙齿漂白的现状与展望

Frontiers in dental medicine Pub Date : 2022-05-31 DOI: 10.3389/fdmed.2022.912857

V. Cavalli, M. Kury, Priscila B. G. Melo, R. V. T. S. M. Carneiro, F. L. Esteban Florez

引用次数: 4