Frontiers in dental medicine最新文献

{"title":"Effects of incorporating magnesium oxide and zirconium dioxide nanoparticles in acrylic resin denture base material: a comparative study.","authors":"Zena J Wally, Ola M Al-Jubouri, Zaid G Al-Jlaihawi, Rajaa M Almusawi, Rasha A Alamoush, Julfikar Haider","doi":"10.3389/fdmed.2025.1667644","DOIUrl":"https://doi.org/10.3389/fdmed.2025.1667644","url":null,"abstract":"<p><strong>Objectives: </strong>The current study aimed to evaluate the effects of incorporating magnesium oxide (MgO) and zirconium oxide (ZrO₂) nanoparticles individually or in combination into heat-cured acrylic resin on the polymer structure, density, surface roughness, hardness and flexural strength for denture base applications.</p><p><strong>Materials and methods: </strong>A total of 280 samples were produced and divided into seven groups (<i>n</i> = 10) according to the percentage of nanomaterial used: pure heat-cured samples (control group) and heat-cured samples containing nanoparticles at 0.5 wt.% MgO, 1 wt.% MgO, 0.5 wt.% ZrO₂, 1 wt.% ZrO₂, 0.5 wt.% MgO-ZrO₂, and 1 wt.% MgO-ZrO₂. Polymer chemistry, density, surface roughness, hardness and flexural strength of the tested groups were determined using Fourier transform infrared (FTIR) spectroscopy, the Archimedes method, a profilometer, a microhardness test and a universal testing machine respectively.</p><p><strong>Results: </strong>The results indicated that both the MgO and ZrO₂ nanoparticles interacted primarily with the carbonyl oxygen atoms, leading to the formation of coordination and ionic bonds. This interaction enhanced crosslinking within the polymer matrix. Additionally, the density of the heat-cured acrylic resin increased in a dose-dependent manner when the nanoparticles were incorporated. The surface roughness decreased with increasing nanoparticle concentration, and the smoothest samples were reported with 1% MgO-ZrO₂. The modified group, which included 0.5% MgO-ZrO₂, exhibited the greatest surface hardness. However, compared with those of the control group, the hardness values notably decreased as the concentration of nanoparticles increased. This reinforcement also significantly improved the flexural strength when the amount of nanoparticles increased.</p><p><strong>Conclusions: </strong>MgO and ZrO₂ nanoparticles strengthen the polymer matrix by forming coordination bonds with carbonyl oxygens, increasing crosslinking. This increased the density and flexural strength while reducing the surface roughness but lowered the hardness at elevated concentrations. These findings suggest the potential for tailored polymer applications, improved denture performance, increased patient comfort, and longer-lasting dental prostheses.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1667644"},"PeriodicalIF":1.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12537696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145350274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does orthodontic postgraduate education influence the choice of orthodontic treatment?","authors":"Sabina Saccomanno, Stefano Saran, Maria Teresa Petricca, Elena Caramaschi, Laura Ferrante, Francesco Inchingolo, Angelo Michele Inchingolo, Andrea Palermo, Gianna Dipalma, Alessio Danilo Inchingolo","doi":"10.3389/fdmed.2025.1665422","DOIUrl":"https://doi.org/10.3389/fdmed.2025.1665422","url":null,"abstract":"<p><strong>Aim: </strong>The purpose of this study is to understand how the training of a clinician influences his or her therapeutic choices in the orthodontic field.</p><p><strong>Materials and methods: </strong>An anonymized questionnaire was submitted to 317 Italian dentists to ask them about their training and what orthodontic therapies they perform. The answers were processed by statistical analysis.</p><p><strong>Results: </strong>221 of 314 respondents (70.3%) had an orthodontic postgraduate education and 93 subjects did not (29.7%). Out of the whole sample, 242 clinicians use functional therapy (i.e., Frankel, Bionator or Andresen), but while 133 of them, after functional therapy, apply both fixed orthodontic appliances (i.e., Straight wire, Tweed or Rickets) and aligners, 79 use only fixed oral appliances, and 19 dentists use only an aligner. The application of a lingual technique is perfectly independent from having an orthodontic postgraduate education or not.</p><p><strong>Conclusion: </strong>Differences were found between dentists with an orthodontic postgraduate education and dentists without it. Most dentists in Italy pursued a postgraduate education. In addition, most orthodontists are dedicated exclusively to orthodontics in their office, while dentists who don't have an orthodontic postgraduate education do not practice orthodontics exclusively in their offices. It is possible to conclude that pursuing a specialization in orthodontics determines advantages for both practitioners and patients: it gives orthodontists those extra skills to customize a diagnosis and daily treatments in a more precise and innovative way, using a wider variety of therapeutic options and relying more on teamwork, for complementary solutions. These additional skills usually increase a treatment's success and decrease complications, which, first and foremost, benefit the patients.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1665422"},"PeriodicalIF":1.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12537687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145350286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, regional and national burden of deciduous dental caries from 1990 to 2021: analysis of risk factors and prediction of trends in 2035.","authors":"Hong Yang, Yong Feng, Li-Yuan Xiao, Kai-Mei Wang, Hong-Chao Feng","doi":"10.3389/fdmed.2025.1624571","DOIUrl":"https://doi.org/10.3389/fdmed.2025.1624571","url":null,"abstract":"<p><strong>Background/aim: </strong>Early childhood caries (ECC) is one of the most prevalent global oral health issues in children under five years old, significantly impacting their overall health and quality of life. This study aimed to analyze the global, regional, and national burden of ECC from 1990 to 2021, identify associated risk factors, and predict trends through 2040. It further examined the influence of socio-demographic factors, sex, and age on ECC incidence and prevalence.</p><p><strong>Patients and methods: </strong>Data from the Global Burden of Disease (GBD) 2021 database were analyzed using Bayesian Meta-Regression models to estimate ECC incidence, prevalence, and years lived with disability (YLDs) across 204 countries and regions. Socio-Demographic Index (SDI) levels, sex, and age-specific trends were assessed. Age-standardized rates and estimated annual percentage changes (EAPCs) were calculated. Predictive models, including ARIMA, were developed to forecast future trends.</p><p><strong>Results: </strong>Between 1990 and 2021, ECC incidence and prevalence showed modest declines globally, with significant variations across SDI regions. High SDI regions exhibited the lowest burden due to effective public health measures, while medium and low SDI regions faced persistent challenges. Sex disparities were observed, with males showing slightly higher rates than females. Children aged 5-9 years bore the highest burden of ECC. Predictions for 2040 indicate a potential rebound in ECC incidence in low and medium SDI regions without targeted interventions.</p><p><strong>Conclusion: </strong>This study highlights the substantial burden of ECC, particularly in under-resourced regions, and underscores the need for tailored public health strategies. Effective prevention, improved healthcare access, and education are critical to reducing ECC burden globally, ensuring better oral health outcomes for children, and addressing disparities across socio-economic, sex, and age groups.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1624571"},"PeriodicalIF":1.8,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12537661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145350281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical considerations in RPD design: application and perspective of finite element method in distal extension removable partial denture rehabilitation.","authors":"Yixuan Zhu, Jiangqi Hu, Bin Luo, Yafei Yuan, Qingsong Jiang","doi":"10.3389/fdmed.2025.1667504","DOIUrl":"10.3389/fdmed.2025.1667504","url":null,"abstract":"<p><p>Removable partial dentures (RPDs) remain a widely used and cost-effective solution for patients with dentition defects. However, their long-term success, particularly in distal extension cases, depends heavily on biomechanical performance. Finite element analysis (FEA) has emerged as a valuable tool for evaluating stress distribution and guiding RPD design. This review synthesizes FEA-based insights into key biomechanical parameters-including abutment selection, clasp geometry, rest position, major connector stiffness, and material properties-with a particular focus on Kennedy Class I and II scenarios, and special attention to implant-supported RPDs (ISRPDs). Recent developments in digital workflows, such as intraoral scanning and CAD/CAM fabrication, have further enabled personalized modeling and rapid optimization. In addition, the integration of artificial intelligence (AI) with FEA shows promises in automating framework generation, predicting stress outcomes, and supporting closed-loop design optimization. While these technologies offer exciting potential, current models still lack integration of patient-specific factors such as mucosal properties, saliva, and gag reflex, contributing to discrepancies between simulations and clinical outcomes. Bridging this gap through improved modeling and data-driven approaches will be key to delivering personalized, biomechanically optimized RPD solutions.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1667504"},"PeriodicalIF":1.8,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12531227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salivary biomarkers for the prognosis of oncological and infectious diseases: a systematic review.","authors":"Heber Isac Arbildo-Vega, Saurav Panda, Fredy Hugo Cruzado-Oliva, Hernán Vásquez-Rodrigo, Rubén Aguirre-Ipenza, Joan Manuel Meza-Málaga, Sara Antonieta Luján-Valencia, Eduardo Luján-Urviola, Carlos Alberto Farje-Gallardo, Tania Belú Castillo-Cornock, Katherine Serquen-Olano, Tania Padilla-Cáceres, Luz Caballero-Apaza, Franz Tito Coronel-Zubiate","doi":"10.3389/fdmed.2025.1662276","DOIUrl":"10.3389/fdmed.2025.1662276","url":null,"abstract":"<p><strong>Objective: </strong>To determine the salivary biomarkers that are used in the prognosis of oncological and infectious diseases.</p><p><strong>Materials and methods: </strong>A bibliographic search was carried out until July 2025, in the biomedical databases: PubMed, Cochrane Library, Scopus, EMBASE, Web of Science (WoS), Scielo, Science Direct and Google Scholar. Studies that were clinical trials, which reported the use of salivary biomarkers for the prognosis of oncological and infectious diseases, without time and language limits, were included. The Cochrane Handbook of Systematic Reviews of Interventions was used to assess the risk of bias of the included studies.</p><p><strong>Results: </strong>The preliminary search yielded a total of 189 articles, discarding those that did not meet the selection criteria, leaving only 16 articles for qualitative synthesis. These studies reported that the most widely used salivary biomarkers in the prognosis of oncological and infectious diseases are cortisol and interleukins.</p><p><strong>Conclusions: </strong>Salivary biomarkers, especially cortisol and key interleukins, demonstrate potential as non-invasive tools for the prognostic assessment and monitoring of oncological and infectious diseases. Further standardization and clinical validation are needed to support their integration into routine practice.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/PROSPERO/view/CRD42021260764, PROSPERO CRD42021260764.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1662276"},"PeriodicalIF":1.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12515936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The long-term efficacy of tetracycline class antimicrobials as local adjuncts in the treatment of chronic periodontitis: a systematic review and meta-analysis.","authors":"Niroshani S Soysa, Samadhi L Jayakody, C N R A Alles","doi":"10.3389/fdmed.2025.1658720","DOIUrl":"10.3389/fdmed.2025.1658720","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;This systematic review assesses the long-term efficacy of tetracycline-class local antimicrobials as adjuncts to scaling and root planing (SRP) in chronic periodontitis. It focuses on improvements in primary outcomes such as probing pocket depth (PPD) and clinical attachment level (CAL), with particular attention to differences in treatment outcomes between smokers and non-smokers. Moreover, the assessed secondary outcomes encompassed bleeding on probing (BOP), gingival index (GI), and plaque index (PI).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Method: &lt;/strong&gt;A systematic search of PubMed, Cochrane Central, Scopus, and Embase identified randomized controlled trials (RCTs) published up to 2024 with ≥6 months follow-up. Long-term efficacy of local tetracyclines was assessed from the selected studies. Meta-analysis calculated weighted mean differences (WMDs) and 95% CIs for the selected periodontal indices using R software. Meta-regression evaluated the impact of study design, assessment approach, treatment phase, and smoking status.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;This systematic review included 52 RCTs assessing the efficacy of adjunctive locally delivered antimicrobials in periodontal therapy. Meta-analysis showed significant benefits in both medium-term (6-9 months) and long-term (12 +  months) outcomes. Medium-term results demonstrated significant PPD reduction (WMD 0.516 mm, 95% CI 0.413; 0.620, &lt;i&gt;P&lt;/i&gt; = 0.0001) and CAL gain (WMD 0.336 mm, 95% CI 0.204; 0.467, &lt;i&gt;P&lt;/i&gt; = 0.0001), while long-term studies showed sustained improvements (PPD: WMD 0.371 mm, 95% CI 0.181; 0.560, &lt;i&gt;P&lt;/i&gt; = 0.0001; CAL: WMD 0.310 mm, 95% CI 0.240; 0.381, &lt;i&gt;P&lt;/i&gt; = 0.0001). Tetracycline fibers showed the greatest medium-term PPD reduction (0.705 mm), followed by minocycline ointment (0.580 mm). Long-term follow-up also demonstrated significant improvements in BOP, PI, and GI (WMD = 0.1-0.3, &lt;i&gt;P&lt;/i&gt; &lt; 0.05). Subgroup analysis revealed non-smokers had greater PPD reduction (0.630 mm vs. 0.112 mm) and CAL gain (0.715 mm vs. 0.464 mm) than smokers (&lt;i&gt;P&lt;/i&gt; &lt; 0.05) in long-term. Meta-regression indicated study design influenced outcomes, with split-mouth designs showing significantly greater improvements [&lt;i&gt;β&lt;/i&gt; = 0.422, 95% CI (0.231; 0.613), &lt;i&gt;P&lt;/i&gt; = 0.0001].&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Discussion: &lt;/strong&gt;Sustained-release tetracyclines with SRP improve long-term outcomes in chronic periodontitis. Non-smokers exhibit greater clinical gains, though smokers also benefit. These results support tailored adjunctive local tetracycline use to optimize outcomes across patient groups. Further large-scale, long-term RCTs are needed to confirm efficacy and refine delivery formulations.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Locally delivered tetracycline-class antimicrobials significantly improve periodontal outcomes, with minocycline showing the most consistent benefits. These findings support the integration of tetracycline-class agents into treatment protocols, with special co","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1658720"},"PeriodicalIF":1.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12511111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of magnesium-containing coatings on the healing of soft tissues surrounding oral titanium abutments: a narrative review.","authors":"Hongya Zheng, Chenxi Shang, Ping Li, Wenjie Zhao, Yumei Niu, Shuang Pan, Shuang Zhang","doi":"10.3389/fdmed.2025.1638027","DOIUrl":"10.3389/fdmed.2025.1638027","url":null,"abstract":"<p><p>The inherent limitations of smooth titanium abutments-particularly inadequate soft tissue sealing that predisposes implants to infection and inflammation-underscore the need for surface modifications. This review synthesizes evidence on magnesium-containing coatings as a bioactive solution to enhance peri-implant soft tissue healing. Through 1) modifying the surface properties of the implant abutment to promote better cell adhesion and proliferation; 2) releasing Mg²⁺ to promote fibroblast migration, collagen synthesis, and angiogenesis; and 3) exerting antimicrobial effects and regulating inflammatory responses, these coatings establish a microenvironment conducive to robust tissue integration. This helps prevent peri-implant infections and inflammation, strengthens soft tissue attachment, and improves the long-term stability of dental implants, providing a new direction for the development of biomedical materials.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1638027"},"PeriodicalIF":1.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12507913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145281969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of implant surface modifications on long-term outcome of surgical peri-implantitis treatment: a systematic review.","authors":"Panagiotis Gardelis, Catherine Giannopoulou, Andreas Stavropoulos, Alkisti Zekeridou","doi":"10.3389/fdmed.2025.1661369","DOIUrl":"10.3389/fdmed.2025.1661369","url":null,"abstract":"<p><strong>Introduction: </strong>Peri-implantitis is an inflammatory disease that compromises peri-implant tissues and supporting bone, potentially leading to implant loss. Although several surgical treatment strategies have been proposed, it remains unclear whether implant surface characteristics (smooth vs. rough) influence long-term treatment outcomes.</p><p><strong>Methods: </strong>A systematic review was conducted to evaluate clinical studies with a minimum follow-up of 3 years that assessed the outcomes of surgical treatment of peri-implantitis in relation to implant surface type. Data extraction focused on recurrence of peri-implantitis, implant survival, clinical parameters, radiographic outcomes, and the type of surgical approach used (reconstructive vs. non-reconstructive).</p><p><strong>Results: </strong>Seventeen clinical studies were included. Outcomes varied according to implant surface characteristics. Rough (modified) surfaces were generally associated with a higher risk of recurrence of peri-implantitis and implant loss compared with smooth (machined/turned) surfaces. Reconstructive surgical approaches, especially those involving bone grafts and membranes, demonstrated more favorable outcomes compared with non-reconstructive approaches.</p><p><strong>Discussion: </strong>Despite observed trends, the certainty of the evidence remains low due to heterogeneity between studies, small sample sizes, and methodological limitations. Further well-designed long-term clinical trials are needed to clarify the role of implant surface characteristics in the long-term success of peri-implantitis surgical treatment.</p><p><strong>Systematic review registration: </strong>PROSPERO (CRD420251129791).</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1661369"},"PeriodicalIF":1.8,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12504269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and risk factors of postoperative complications following periodontal flap surgery: a retrospective study.","authors":"Hongjiang Gu, Wei Liu, Xiaoyu Xu, Yinjie Shen","doi":"10.3389/fdmed.2025.1668844","DOIUrl":"10.3389/fdmed.2025.1668844","url":null,"abstract":"<p><strong>Background: </strong>Periodontal flap surgery is a common procedure for treating advanced periodontal disease, but postoperative complications such as pain, infection, and delayed healing are frequent. This study aims to investigate the incidence of postoperative complications and identify key risk factors, contributing to more personalized surgical management.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 121 patients who underwent periodontal flap surgery. Patient demographics, clinical data (e.g., age, probing depth, clinical attachment loss), and surgical variables (e.g., incision type, surgery duration) were collected. Logistic regression analysis was performed to identify significant predictors of postoperative complications. The complications analyzed included dentin hypersensitivity, excessive pain, infection, and gingival bleeding.</p><p><strong>Results: </strong>Postoperative complications occurred in 44.63% of patients. Age was a significant predictor, with each additional year increasing the risk of complications by 12% (<i>p</i> < 0.001). Clinical attachment loss was strongly associated with complications (<i>p</i> = 0.009). Semilunar incisions, typically used in localized mild cases, were associated with a lower incidence of complications compared to trapezoidal incisions (<i>p</i> < 0.001). Smoking also significantly increased the risk of complications in both the univariate and multivariate analyses (<i>p</i> < 0.05). In the univariate analysis, both preoperative antibiotics and preoperative analgesics were associated with a reduced risk of complications (<i>p</i> < 0.05), but these effects were not significant in the multivariate analysis (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>This study highlights age, clinical attachment loss, smoking, and surgical incision type as significant predictors of postoperative complications following periodontal flap surgery. The findings underscore the need for personalized surgical approaches, particularly in older patients and those with severe periodontal disease.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1668844"},"PeriodicalIF":1.8,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12504384/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mesiodistal width correlation between primary and successor mandibular teeth: implication for early orthodontic diagnosis.","authors":"Aleyna Cakir, Annika Both, Christian Kirschneck, Nikolaos Daratsianos, Cristiano Miranda de Araújo, Juliane Corá, Erika Calvano Küchler, Svenja Beisel-Memmert","doi":"10.3389/fdmed.2025.1659242","DOIUrl":"10.3389/fdmed.2025.1659242","url":null,"abstract":"<p><strong>Background: </strong>Most studies on permanent tooth width prediction focus on the predictive value of permanent teeth, however only a few studies examine the predictive value of primary teeth. The aim of this study was to investigate the correlation between the mesiodistal widths of the mandibular primary canines and molars and those of their permanent successors. In addition, the study evaluated whether the mesiodistal width of the primary canines and molars can serve as reliable predictors for the width of the permanent mandibular first molars.</p><p><strong>Methods: </strong>This cross-sectional study analyzed records from 143 orthodontic patients (78 males and 65 females) who had digitized dental models in the mixed and in the permanent dentition stage. Mesiodistal measurements were performed on left-sided mandibular permanent teeth (canines, first and second premolars, first molar), and primary teeth (canines, first and second molars). The Pearson correlation coefficient test was used to determine the correlation strength between the mesiodistal dimensions of primary and permanent teeth (<i>p</i> < 0.05).</p><p><strong>Results: </strong>Significant correlations were found between second primary molars and second premolars (Pearson <i>r</i> = 0.400-0.461) as well as between primary and permanent canines (Pearson <i>r</i> = 0.462-0.512), across the total sample and within both sexes. The dimensions of all three evaluated primary teeth were correlated with first permanent molar with r ranging from 0.402 to 0.625. The primary first molar showed a weak correlation with the first premolar for the total sample (Pearson <i>r</i> = 0.240) and males (Pearson <i>r</i> = 0.302), and none was observed for female patients (Pearson <i>r</i> = 0.048).</p><p><strong>Conclusions: </strong>A link between primary and permanent tooth width of canines and posterior dentition was observed, but a difference between sexes exists. Therefore, primary teeth may offer early insight into future space requirements, however their predictive strength is influenced by tooth type and sex.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1659242"},"PeriodicalIF":1.8,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12504356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}