Frontiers in dental medicine最新文献

{"title":"Nutritional characteristics of patients with dry mouth and/or Sjögren disease in a Hungarian cohort.","authors":"György Tóth, Dorottya Kiss, Csilla Erdei, Krisztina Márton","doi":"10.3389/fdmed.2026.1879266","DOIUrl":"https://doi.org/10.3389/fdmed.2026.1879266","url":null,"abstract":"<p><strong>Background: </strong>People with any form of dry mouth may have problems with eating, swallowing, speaking, taste perception, wearing dentures, and maintaining good oral health. Subsequently, it can have a major impact on the quality of life through its effects on the qualitative and quantitative parameters of nutrition. Nevertheless, little is known about the effects of different foods and nutrients on salivation and orofacial sicca symptoms. Despite this, the literature on the relationship between xerostomia (x), hyposalivation (h), Sjögren disease (SD), and nutrition is relatively sparse.</p><p><strong>Objective: </strong>The authors aimed to evaluate the dietary habits of middle-aged patients with newly diagnosed dry mouth and/or SD compared with healthy controls.</p><p><strong>Methods: </strong>A total of 128 participants (10 men and 118 women; mean age: 53 ± 13 years) enrolled in the study. A 35-question questionnaire containing a \"computer-assisted personal interview\"-type exploratory survey was used to record body mass index (BMI), possible food allergies, harmful habits, used sources of health-related information, and nutritional habits such as frequency and types of daily meals, for example, fruit, vegetable, meat, vitamin, and trace element consumption. Subjective sicca symptoms (xerostomia, xerophthalmia) were also assessed by guided questions, while the unstimulated whole saliva (UWS) flow rate was determined by the spitting method to confirm hyposalivation. SD was diagnosed based on the 2016 ACR-EULAR diagnostic criteria. Participants were divided into four groups: healthy controls (c), xerostomia (x), hyposalivation (h), and SD. Patients' data were compared with those of healthy controls.</p><p><strong>Results: </strong>The mean BMI of the participants did not show a significant difference from the normal BMI, although it was slightly elevated in all four patient groups (c: 24.7; x: 25.4; h: 26.2; SD: 25.2). The smoking percentage was high in the SD group: 49% vs. 18% in the c group (<i>p</i> = 0.01), while it was 0 in both the x and h groups. The percentage of food allergy and/or intolerance (lactose, milk protein or gluten, floating, and bloating) was increased among all patients compared with healthy controls: 50% of patients with xerostomia and 44% and 68% with those with hyposalivation compared with only 16% of healthy controls (<i>p</i> < 0.05, <i>p</i> < 0.05, <i>p</i> < 0.00001, respectively). Similarly, liquid consumption was between 1.9 and 2.2 L/day in all groups, and the interviewed participants preferred water ( approximately 78%) and diary milk products (more than 80%). Significantly less patients with xerostomia consumed alcohol (2.6 vs. 18%, <i>p</i> < 0.05) and vegetable milk regularly (2.6 vs. 18%, <i>p</i> < 0.05) compared with healthy controls; alcohol consumption was also low in the h (4.7%) and SD (6.4%) group of patients. There was no significant difference in the intake of different vitamins and t","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1879266"},"PeriodicalIF":2.7,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13541545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From margins to mainstream: reimagining oral health in integrated healthcare.","authors":"Melanie Aley, Salima Alibhai, Amanda Bloomfield-Gallie, Jamie Dooley, Gitana Rederiene, Adam Rogers, Roisin McGrath","doi":"10.3389/fdmed.2026.1905156","DOIUrl":"https://doi.org/10.3389/fdmed.2026.1905156","url":null,"abstract":"<p><p>Oral health remains persistently marginalised within mainstream healthcare despite the global burden of preventable oral diseases and growing recognition of the need for integrated, person-centred care. This perspective paper examines the structural, professional, and educational barriers that continue to separate oral health from broader health systems, including limited interprofessional collaboration, fragmented service delivery, and underutilisation of the oral health practitioner workforce. Drawing on international policy directions and emerging models of integrated care, the paper argues that oral health practitioners are well positioned to support prevention, early intervention, health promotion, and care coordination across healthcare settings. The authors highlight the importance of workforce utilisation, interprofessional education, policy alignment, and system-level collaboration in advancing equitable access to oral healthcare. Through a globally informed perspective, this paper proposes practical priorities for embedding oral health within integrated healthcare systems and repositioning oral health as a fundamental component of overall health and wellbeing.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1905156"},"PeriodicalIF":2.7,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13541503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of papain-based gel and air-abrasion enamel pretreatments on microleakage, sealant penetration, and shear bond strength of fissure sealant materials: an <i>in vitro</i> study.","authors":"Lozan Rashid, Aras Rauf","doi":"10.3389/fdmed.2026.1908853","DOIUrl":"https://doi.org/10.3389/fdmed.2026.1908853","url":null,"abstract":"<p><strong>Introduction: </strong>Establishing a durable seal between enamel and fissure sealant materials is critical for the long-term prevention of occlusal caries, particularly in anatomically complex pits and fissures. This <i>in vitro</i> study evaluated the effects of chemical pretreatment with a papain-based gel and mechanical pretreatment with air abrasion on the microleakage, sealant penetration, and shear bond strength of two pit and fissure sealant materials.</p><p><strong>Methods: </strong>A total of 120 sound human premolars were randomly allocated according to sealant type, resin-based sealant (RBS) or resin-modified glass ionomer cement (RMGIC), and pretreatment protocol: no pretreatment, enzymatic papain-based gel, or air abrasion. Following sealant application and thermocycling, microleakage was evaluated by dye penetration under a stereomicroscope. Sealant penetration was measured in relation to fissure morphology using ImageJ software, and shear bond strength was evaluated using a universal testing machine.</p><p><strong>Results: </strong>RBS showed significantly lower microleakage than RMGIC, indicating better sealing ability. Papain-based gel pretreatment significantly reduced microleakage in the RBS group without affecting sealant penetration or shear bond strength; however, no comparable improvement was observed in the RMGIC group. In contrast, air abrasion pretreatment did not produce a significant improvement in any of the evaluated outcomes. Fissure morphology significantly influenced sealant penetration, with wider fissure patterns demonstrating greater penetration.</p><p><strong>Discussion: </strong>These findings indicate that fissure sealant performance is primarily influenced by material properties and fissure morphology, while the benefit of enamel pretreatment appears to be material-dependent.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1908853"},"PeriodicalIF":2.7,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13541521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parameter-level comparison of artificial intelligence and manual cephalometric measurements: a systematic review and meta-analysis.","authors":"Franz Tito Coronel-Zubiate, Consuelo Marroquín-Soto, Joan Manuel Meza-Málaga, Sara Antonieta Luján-Valencia, Alejandro Placeres-Hernández, Angie Vanessa Carmona-Sanchez, Fredy Hugo Cruzado-Oliva, Carlos Alberto Farje-Gallardo, Jeanile Zuta-Rojas, Eduardo Luján-Urviola, Heber Isac Arbildo-Vega","doi":"10.3389/fdmed.2026.1820984","DOIUrl":"https://doi.org/10.3389/fdmed.2026.1820984","url":null,"abstract":"<p><strong>Introduction: </strong>Prior work has largely focused on landmark-localization error and runtime; whether AI-derived parameter-level measurements differ systematically from those obtained by manual cephalometric analysis remains unclear.</p><p><strong>Objective: </strong>To compare parameter-level cephalometric measurements obtained using AI systems with manual reference methods through a systematic review and meta-analysis; secondarily, to narratively summarize any reported diagnostic metrics (κ/ICC, sensitivity/specificity, AUC) without pooling.</p><p><strong>Methods: </strong>Six databases (PubMed, Scopus, Web of Science, IEEE Xplore, EBSCO, and SciELO) were searched with no time restriction (inception to 20 September 2025) and no language limits; citation chasing was performed (Google Scholar). Eligible studies directly compared AI-based and manual cephalometric tracings. Random-effects meta-analyses were conducted only for parameter-level cephalometric measurements (primary outcomes), using standardized mean differences (Hedges' <i>g</i>) with 95% confidence intervals (CIs). Statistical heterogeneity was quantified using the <i>I</i> ² statistic. Sensitivity/specificity/AUC were not meta-analyzed due to heterogeneous thresholds and ≤3 studies per metric; no bivariate or HSROC model was applied. Risk of bias was assessed with QUADAS-2 and certainty with GRADE. Legacy rule/knowledge-based reports were summarized narratively and not pooled. Registration: OSF (DOI: 10.17605/OSF.IO/WKMVD).</p><p><strong>Results: </strong>Twenty-two studies published between 2020 and 2025 were included. AI showed small and generally non-significant differences compared with manual methods across most evaluated parameters, although the certainty of evidence was low to moderate and heterogeneity was considerable for several outcomes. A statistically significant but small advantage was observed for the ANB angle (<i>g</i> = 0.28; 95% CI: 0.03-0.53; <i>p</i> = 0.03), with uncertain clinical relevance. Complementary legacy studies were described narratively and excluded from pooling. GRADE certainty ranged from low to moderate.</p><p><strong>Conclusions: </strong>AI-assisted cephalometric analysis produces parameter-level measurements comparable to manual tracings for most evaluated parameters; a small statistical difference for ANB was observed without clear clinical relevance. However, the certainty of evidence is limited by heterogeneity, publication bias, and lack of multicenter validation. AI may complement cephalometric workflows and save time, but it requires expert supervision and does not replace comprehensive orthodontic diagnosis or treatment planning. Funding/COI: As declared in the manuscript.</p><p><strong>Systematic review registration: </strong>https://doi.org/10.17605/OSF.IO/WKMVD.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1820984"},"PeriodicalIF":2.7,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13541505/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of ethyl chloride topical anesthesia application on pain perception during intra-oral injections in children compared to benzocaine gel-a single-blind randomized controlled trial.","authors":"Nagah Abdelrahman, Manal Al Halabi, Mawlood Kowash, Iyad Hussein, Anas Salami","doi":"10.3389/fdmed.2026.1925109","DOIUrl":"10.3389/fdmed.2026.1925109","url":null,"abstract":"<p><strong>Background: </strong>Pain management during local anesthesia administration is a critical factor in pediatric dentistry. This assessor-blind, parallel-group, superiority randomized controlled trial (ClinicalTrials.gov: NCT06011005) aimed to determine whether ethyl chloride (EC) spray applied via a cotton pellet provides superior pain reduction compared to 20% benzocaine (BC) gel during intra-oral local anesthetic injections in children.</p><p><strong>Methods: </strong>Fifty-seven healthy children aged 7-10 years requiring routine dental local anesthesia were randomized to Group A (20% BC gel, <i>n</i> = 29) or Group B (EC spray via cotton pellet, <i>n</i> = 28). The primary outcome was physiological stress measured by change in heart rate (HR). Secondary outcomes included self-reported pain (Faces Pain Scale, FPS) and observed behavioral response (Sound-Eye-Motor scale, SEM). The outcomes assessor was blinded to the topical agent used. Between-group differences in change scores were analyzed using the Mann-Whitney <i>U</i> test with Hodges-Lehmann median differences and bootstrap 95% confidence intervals.</p><p><strong>Results: </strong>Both groups demonstrated slight increases in HR following the injection; however, the magnitude of change was not significantly different between the groups (BC: +4.03 bpm vs. EC: +2.14 bpm; Mann-Whitney <i>U p</i> = 0.310; 95% CI of mean difference: -1.53 to 5.35). Additionally, there were no statistically significant differences between the groups regarding self-reported pain levels (FPS change: BC +1.31 vs. EC +1.25; <i>p</i> = 0.546; 95% CI: -1.03 to 1.08) or behavioral responses (SEM change: BC +0.10 vs. EC +0.11; <i>p</i> = 0.971; 95% CI: -0.22 to 0.21).</p><p><strong>Conclusion: </strong>The superiority trial did not reveal a statistically significant difference between the use of ethyl chloride spray and 20% benzocaine gel across any of the measured outcomes. Both anesthetic agents produced comparable physiological responses, self-reported experiences, and behavioral reactions during intra-oral local anesthetic injections in cooperative children aged 7-10 years.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1925109"},"PeriodicalIF":2.7,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13533958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of silver modified atraumatic restorative treatment (SMART) versus atraumatic restorative treatment (ART) for caries control in primary teeth: a systematic review and meta-analysis.","authors":"Katia Noemi Rubio-Membrillo, María Victoria Espinoza-Salcedo, Heber Isac Arbildo-Vega, Omar Edmundo Rojas-Rojas, Edith Esther Delgado-Asmat, Jhair Alexander León-Rodríguez, Franz Tito Coronel-Zubiate","doi":"10.3389/fdmed.2026.1914881","DOIUrl":"10.3389/fdmed.2026.1914881","url":null,"abstract":"<p><strong>Background: </strong>Early childhood caries represents a severe global public health problem. Faced with this, Atraumatic Restorative Treatment (ART) and Silver Modified Atraumatic Restorative Treatment (SMART) have positioned themselves as minimally invasive approaches. The objective of this study was to evaluate and compare the clinical efficacy of SMART versus conventional ART for caries control in primary teeth.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were conducted in accordance with the PRISMA guidelines, searching for randomized clinical trials (RCTs) across seven databases up to March 2026. Studies with a minimum follow-up period of 6 months were included. The risk of bias was assessed using the RoB 2 tool, and the certainty of evidence was evaluated using the GRADE approach.</p><p><strong>Results: </strong>Seven reports derived from six randomized clinical trials with an overall low risk of bias were included in the qualitative synthesis, representing 398 unique pediatric participants. One trial generated two complementary publications reporting different outcomes; therefore, only the publication reporting clinical success contributed to the quantitative synthesis. A total of six randomized clinical trials were included in the meta-analysis, which showed no statistically significant differences in overall clinical success between SMART and ART (OR = 1.28; 95% CI: 0.91-1.80; <i>p</i> = 0.16). Furthermore, Trial Sequential Analysis (TSA) demonstrated that the cumulative evidence remains inconclusive.</p><p><strong>Conclusions: </strong>There is no statistically significant difference in overall clinical success between SMART and ART for the primary dentition. Both are viable and effective strategies; however, the certainty of the available evidence is low, and therefore future large-scale RCTs are required to establish definitive clinical guidelines.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/PROSPERO/view/CRD420261325936, PROSPERO CRD420261325936.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1914881"},"PeriodicalIF":2.7,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13534126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular cytokine-dependent mechanisms of periodontitis pathogenesis and the potential for pharmacological IL-1 modulation in disease treatment.","authors":"Igor Belenichev, Olena Popazova, Oksana Dmytriieva, Sergiy Chertov, Nina Bukhtiyarova, Victor Ryzhenko, Sergiy Oliynyk, Suyeon Lee, Kyu-Ho Yi","doi":"10.3389/fdmed.2026.1849807","DOIUrl":"10.3389/fdmed.2026.1849807","url":null,"abstract":"<p><p>Periodontitis (P) is one of the most common human dental diseases, with significant medical and social implications. According to the World Health Organization, more than 45% of the adult population worldwide exhibits clinical signs of periodontitis, with 10%-15% of cases becoming generalized with destruction of the alveolar bone. This review presents the results of modern research demonstrating that the etiopathogenesis of periodontitis is not limited to local microbial factors; systemic, social, and behavioral factors can play a significant role, determining the body's susceptibility to chronic inflammation. In this study, we focus on the role of cytokines in the athogenesis of periodontitis. Based on modern research, we demonstratethe general biological significance of cytokines and their role in initiating periodontal inflammation and systemic diseases associated with periodontitis. The molecular and biochemical cytokine-dependent mechanisms of initiation and progression of oxidative stress in periodontitis are covered in detail. The role of individual cytokines in the pathogenesis of periodontitis is shown: interleukin-1 (IL-1), IL-6, tumor necrosis factor (TNF-α), interferon-gamma, IL-10, IL-23, IL-17, and Th17 cells. The review presents a modern approach to complex drug therapy of periodontitis. The arsenal of antiseptics, antibiotics, and synthetic antimicrobial agents available to dentists is presented. A new approach is demonstrated in the use of probiotics-live microorganisms (probiotics, symbiotics, and bacteriophages) that maintain the balance of the oral microbiome. Beyond standard antimicrobial and anti-inflammatory therapies, host modulators, antioxidants, and bioregulatory agents play a vital role in treating P. They effectively suppress proinflammatory cytokines, mitigate oxidative stress, and improve metabolic activity in affected tissues. We present data on the development of individual regenerative structures using bioactive polymers and 3D printing for the future treatment of chronic periodontitis, as well as the potential use of biomaterials with nanostructured components, collagen matrices with nanoparticles, hydrogels with functional peptides, synthetic polymers with a modest antibacterial effect, and transplantation of mesenchymal stem cells, as well as bioactive scaffolds with stem cells. The most important section of the review is devoted to the clinical and pharmacological properties of cytokine modulators-TNF-α blockers, IL-6 blockers, and IL-1 blockers. Using current research results, including our own, we demonstrate the potential of using an IL-1 receptor antagonist and its new dosage form, such as a dental gel.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1849807"},"PeriodicalIF":2.7,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13535533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of surface integrity, longevity of posterior tooth-colored crowns fabricated by conventional, CAD/CAM, and 3D printing techniques.","authors":"Tanner Hunt, Jacob Nichols, Preston Harmon, Neamat Hassan Abubakr","doi":"10.3389/fdmed.2026.1900498","DOIUrl":"10.3389/fdmed.2026.1900498","url":null,"abstract":"<p><strong>Introduction: </strong>This <i>in vitro</i> study evaluated internal and marginal surface roughness and simulated thermocycling survival of posterior tooth-colored crowns fabricated using conventional laboratory, CAD/CAM milling, and digital light processing 3D printing workflows.</p><p><strong>Methods: </strong>The roughness analysis included 46 crowns allocated to six groups: lab-made crowns (<i>n</i> = 6), IPS e.max CAD (<i>n</i> = 8), IPS Empress CAD (<i>n</i> = 8), Lava Ultimate (<i>n</i> = 8), IPS e.max ZirCAD (<i>n</i> = 8), and 3 D SprintRay Ceramic (<i>n</i> = 8). Internal and marginal arithmetic mean roughness (Ra, µm) were measured with a 3D non-contact profilometer. Because residual normality and variance homogeneity assumptions were not satisfied, group differences were analyzed using Kruskal-Wallis tests followed by Holm-adjusted pairwise Mann-Whitney <i>U</i> tests.</p><p><strong>Results: </strong>Internal Ra differed significantly among groups (<i>H</i> = 25.76, df = 5, <i>p</i> < 0.001). 3D printed SprintRay Ceramic showed the highest internal Ra (29.27 ± 5.45 µm) and was significantly rougher internally than every other group after Holm correction. Marginal Ra also differed significantly among groups (<i>H</i> = 41.86, df = 5, <i>p</i> < 0.001). IPS e.max CAD showed the highest marginal Ra (26.81 ± 1.73 µm), followed by lab-made crowns (19.31 ± 6.40 µm), whereas IPS e.max ZirCAD showed the lowest marginal Ra (4.82 ± 1.03 µm).</p><p><strong>Conclusion: </strong>Within the limitation of the present study material type and fabrication workflow significantly influenced internal and marginal surface roughness of posterior tooth-colored crowns. The crowns survival rates were more closely associated with material type than fabrication method.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1900498"},"PeriodicalIF":2.7,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13529506/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148875783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: Data driven analytics in orofacial pain.","authors":"Linda Sangalli, Akhilanand Chaurasia, Maria Bankvall","doi":"10.3389/fdmed.2026.1959814","DOIUrl":"10.3389/fdmed.2026.1959814","url":null,"abstract":"","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1959814"},"PeriodicalIF":2.7,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13530725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"3D Evaluation of material-dependent volumetric and interfacial changes in CAD/CAM partial crowns: a semi-automated micro-CT approach.","authors":"Ellen Schulz-Kornas, Olivia Giesa, Tobias Meißner, Nadia Oberück, Philipp D Lösel, Stephan Handschuh, Dirk Ziebolz, Rainer Haak","doi":"10.3389/fdmed.2026.1843676","DOIUrl":"10.3389/fdmed.2026.1843676","url":null,"abstract":"<p><strong>Objectives: </strong>Changes in the 3D volumes, interfaces, and interfacial gap formation were examined of adhesively luted lithium disilicate (LS2) and resin-based composite (RBC) partial crowns during artificial aging and imaged by micro-computed tomography (micro-CT).</p><p><strong>Methods: </strong>Sixteen human mandibular molars were restored using either 8 CAD/CAM partial crowns made of LS2 (IPS e.max® CAD) or RBC (Tetric® CAD). After adhesive luting (Variolink® Esthetic DC, adhesive luting composite), artificial aging [water storage for 90 days (t1) and thermo-mechanical loading (t2)], the partial crowns were analyzed by micro-CT (Avizo, Biomedisa). Paired <i>t</i>-test, ANOVA and Tukey HSD test (<i>α</i> = 0.05) were used to analyze area and volume parameters; e.g., luting space volume (VLS), luting space thickness (TLS), and partial crown contact area to the cavity and tooth tissues (CPT).</p><p><strong>Results: </strong>Across artificial aging, most area parameters and all four volume parameters remained stable in both materials. Yet, there were changing values in areas of direct contact between the partial crown material and the tooth tissues: CPE, CPT were generally smaller at t1 for LS2 (2.2 ± 1.2%) compared to RBC (4.5 ± 1.3%), especially at the inflection and saddle points of the round preparation form. Across both time points, LS2 showed consistently higher mean luting space thickness than RBC. It remained without gap progression.</p><p><strong>Conclusions: </strong>The semi-automated 3D micro-CT analysis enables a comprehensive evaluation of adhesive interfaces and may help to develop new ideas to enhance long-term restoration outcomes. RBC partial crowns had more surfaces in direct contact with the cavity floor than LS2 partial crowns.</p><p><strong>Clinical significance: </strong>The approach with Biomedisa has potential translational value and may enable individualized quality control and long-term monitoring of adhesive restorations in clinical practice. Both materials achieve comparable survival rates, wear resistance, and interface stability under simulated conditions and when minimum material thickness is respected.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"7 ","pages":"1843676"},"PeriodicalIF":2.7,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13529759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148875773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}