Frontiers in dental medicine最新文献

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Assessment of root resorption on lateral incisors after primary canine extraction treating mesioangular displaced permanent canines: a randomised controlled trial.
IF 1.5
Frontiers in dental medicine Pub Date : 2025-01-21 eCollection Date: 2024-01-01 DOI: 10.3389/fdmed.2024.1456985
Narmin Helal, Reem Naaman, Najlaa Alamoudi, Azza El-Housseiny, Fatima Jadu
{"title":"Assessment of root resorption on lateral incisors after primary canine extraction treating mesioangular displaced permanent canines: a randomised controlled trial.","authors":"Narmin Helal, Reem Naaman, Najlaa Alamoudi, Azza El-Housseiny, Fatima Jadu","doi":"10.3389/fdmed.2024.1456985","DOIUrl":"10.3389/fdmed.2024.1456985","url":null,"abstract":"<p><strong>Aim: </strong>Root resorption (RR) of the adjacent maxillary lateral incisors is considered the most common complication of displaced maxillary canines. The aim of this study was to assess the effect of interceptive extraction of the primary canines on the condition of the roots of permanent neighbouring teeth to mesioangular displaced canines (MDC). In addition, this study aimed to investigate the relationship between the position of the unerupted canine and the risk of RR in adjacent lateral incisors.</p><p><strong>Design: </strong>Randomised controlled clinical trial.</p><p><strong>Methods: </strong>Eighty-five patients 9-12-year-old with MDC were allocated equally to either an extraction group (EG) or a control group (CG). Of the sample, 33 were males (38.8%), and 52 were females (61.2%). Among this sample, 81 canines (51.9%) were buccally displaced, 34 canines (21.8%) were palatally displaced, and 41 canines (26.3%) were mid-alveolar. All subjects underwent cone-beam computed tomography examination to determine the presence, stage, and level of lateral incisor root resorption (RR). Measurements were performed at T0 and repeated at a 12-month follow-up (T2).</p><p><strong>Results & statistics: </strong>Root resorption (RR) was present in 28.2% of lateral incisors at the baseline assessment (T0) and exhibited a significant increase at the 12-month follow-up (T12). This marked increase in resorption severity was evident between T0 and T12 (<i>P</i> = 0007), regardless of group allocation. There was a significant increase in the degree of resorption between T2 and T0, with a mean difference equals to 0.31 (0.73), <i>P</i> < 0.0001. While there was no statistically significant difference in resorption levels between the extraction and control groups at T0 (<i>P</i> = 0.11), RR occurred more frequently with midalveolar (34.1%) and palatal (32.3%) displacements than with buccal displacements (23.5%). Severe resorption was observed more frequently in cases involving palatally displaced canines within both groups, but it did not reach statistical significance.</p><p><strong>Conclusions: </strong>Lateral incisor root resorption (RR) progressed significantly within a 12-month period irrespective of treatment modality. RR occurred more frequently with midalveolar and palatal displacement with a trend towards increased RR severity in cases with palatally displaced canines. Early clinical evaluation and consistent monitoring is essential for early detection and potential intervention in patients with mesioangular canine displacement.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1456985"},"PeriodicalIF":1.5,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibacterial activity of biodentine against Enterococcus faecalis: a systematic review.
IF 1.5
Frontiers in dental medicine Pub Date : 2025-01-21 eCollection Date: 2024-01-01 DOI: 10.3389/fdmed.2024.1498353
Hasan Subhi, Nashwah Subhi, Salah Alhaidary, Mahmood S Azeez, Abedelmalek Kalefh Tabnjh
{"title":"Antibacterial activity of biodentine against <i>Enterococcus faecalis</i>: a systematic review.","authors":"Hasan Subhi, Nashwah Subhi, Salah Alhaidary, Mahmood S Azeez, Abedelmalek Kalefh Tabnjh","doi":"10.3389/fdmed.2024.1498353","DOIUrl":"10.3389/fdmed.2024.1498353","url":null,"abstract":"<p><strong>Introduction: </strong>Biodentine is a well-known endodontic material that is applied in various endodontic therapies. <i>Enterococcus faecalis</i> (<i>E. faecalis</i>) is associated with endodontic failure and persistent periapical infection. The purpose of this systematic review was to summarize the available evidence regarding the antibacterial activity of Biodentine against <i>E. faecalis</i> and to compare it to other commercial endodontic materials.</p><p><strong>Methods: </strong>An electronic search of literature was conducted in PubMed, Scopus, Web of Science, and Google Scholar in addition to a manual search in specialized journals up to May 2024. The eligibility criteria, data extraction, and evaluation of risk of bias were assessed by two independent authors. The risk of bias was evaluated in accordance with Modified CONSORT checklist items for pre-clinical in vitro studies on dental materials.</p><p><strong>Results: </strong>Out of 343 studies, thirty-seven fulfilled the inclusion criteria and were included in this review. Thirty studies reported a good antibacterial efficacy of Biodentine against <i>E. faecalis</i>. Biodentine was superior to or, at least, as efficacious as MTA, MTA Angelus, GIC, RMGIC, DiaRoot BioAggregate, NeoPutty, iRoot FS, MTA Repair HP, MTA Biorep, Well-Root PT, Activa, NeoMTA 2, Calcimol LC, TotalFill, and IRM. The findings were supported by studies with medium to high risk of bias (low quality).</p><p><strong>Conclusions: </strong>Considering the limitations of this systematic review, there is accumulating evidence on the antibacterial activity of Biodentine against <i>E. faecalis</i> in context of endodontics. However, randomized clinical trials with well-designed and robust methodologies are required in order to provide information about its clinical behaviour.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1498353"},"PeriodicalIF":1.5,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family factors associated with dental caries among 5-year-old preschool children.
IF 1.5
Frontiers in dental medicine Pub Date : 2025-01-20 eCollection Date: 2024-01-01 DOI: 10.3389/fdmed.2024.1473194
Giovanna Torqueto Castilho, Marília Narducci Pessoa, Caroline Correa de Oliveira, Letícia Santos Alves de Melo, Elaine Pereira Silva Tagliaferro, Vanessa Pardi
{"title":"Family factors associated with dental caries among 5-year-old preschool children.","authors":"Giovanna Torqueto Castilho, Marília Narducci Pessoa, Caroline Correa de Oliveira, Letícia Santos Alves de Melo, Elaine Pereira Silva Tagliaferro, Vanessa Pardi","doi":"10.3389/fdmed.2024.1473194","DOIUrl":"10.3389/fdmed.2024.1473194","url":null,"abstract":"<p><strong>Background: </strong>Although dental caries is largely preventable, it remains highly prevalent among children.</p><p><strong>Aim: </strong>Evaluate family factors associated with the prevalence of dental caries in 5-year-old children.</p><p><strong>Design: </strong>This cross-sectional study recruited 5-year-old children from public preschools in Araraquara, São Paulo, Brazil. Data on sociodemographic factors, family routines, and oral health practices were gathered via a self-administered questionnaire completed independently by caregivers. Children received a dental clinical examination at school and caries experience was recorded using the dmft and SiC (Significant Caries index) indexes following the World Health Organization (WHO) criteria.</p><p><strong>Results: </strong>Data analysis was performed using Chi-square and multiple logistic regression using a significance level of 5%. Of the 578 children in the study, 67.3% were caries-free. The mean dmft index was 1.14 (SD = 2.24), while the SiC index stood at 3.46 (2.69). Factors such as income, caregiver assistance with toothbrushing, caregiver perception of child and parent oral health, and prioritization of dental visits within the family were associated with caries presence.</p><p><strong>Conclusions: </strong>Overall, dental caries prevalence was low in this population, with family factors demonstrating significant associations with dental caries. The attitudes of caregivers regarding oral health appear to wield considerable influence over the dental health of their children.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1473194"},"PeriodicalIF":1.5,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interdental papilla recession and reconstruction of the lost triangle: a review of the current literature.
IF 1.5
Frontiers in dental medicine Pub Date : 2025-01-17 eCollection Date: 2024-01-01 DOI: 10.3389/fdmed.2024.1537452
Sanabel O Barakat
{"title":"Interdental papilla recession and reconstruction of the lost triangle: a review of the current literature.","authors":"Sanabel O Barakat","doi":"10.3389/fdmed.2024.1537452","DOIUrl":"10.3389/fdmed.2024.1537452","url":null,"abstract":"<p><p>Interdental papilla (IDP) deficiency and the presence of gingival black triangles (GBT) are major concerns for both patients and dentists, as the IDP plays an important role in esthetics due to its strong association with the patient's smile. Interdental papilla deficiency is frequent among different populations, with a tendency to increase with age and in patients with periodontal disease. In addition, GBT causes phonetic problems, food impaction, plaque accumulation, and increased risk for root caries. The small dimensions of the IDP and the limited vascular supply to the interproximal space render treatment modalities of receded papillae unpredictable. Still, and based on the etiological factors, several non-surgical treatment options, including correction of traumatic oral hygiene practices, restorative interventions, papilla priming, papilla enhancement with either autologous fibroblast injection or hyaluronic acid, and orthodontic therapy, have been proposed to fill the GBT. In addition, different surgical techniques-with or without grafting biomaterials-have also been introduced to reconstruct the lost papilla. Nonetheless, there is no gold standard set yet. Further, systematic reviews evaluating the efficacy of surgical reconstruction of deficient IDP are still lacking due to the scarcity of large-scale clinical trials and the absence of long-term clinical outcomes. The aim of this review was to identify various causes of IDP recession as well as to explore the available treatment modalities to reconstruct the lost papilla.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1537452"},"PeriodicalIF":1.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An updated look at the use of silver diamine fluoride in U.S. dental schools' predoctoral curriculum-a survey.
IF 1.5
Frontiers in dental medicine Pub Date : 2025-01-14 eCollection Date: 2024-01-01 DOI: 10.3389/fdmed.2024.1466962
Benas Jakubauskas, Sarah Pagni, Andrea G Ferreira Zandona
{"title":"An updated look at the use of silver diamine fluoride in U.S. dental schools' predoctoral curriculum-a survey.","authors":"Benas Jakubauskas, Sarah Pagni, Andrea G Ferreira Zandona","doi":"10.3389/fdmed.2024.1466962","DOIUrl":"10.3389/fdmed.2024.1466962","url":null,"abstract":"<p><p>This survey aimed to update Silver Diamine Fluoride (SDF) use/teaching in U.S. predoctoral dental education programs in comparison to a 2016 survey, considering the COVID-19 pandemic. An online survey via email was sent to all accredited U.S. predoctoral dental education programs (<i>n</i> = 68) in January 2022. A total of 39 schools (57% response rate) responded to the survey, and all 39 of them reported that SDF was now part of their curriculum, significantly different (<i>p</i> < 0.001) from 2016 (68% of schools). Significant changes (<i>p</i> < 0.001) were reported in the survey responses from 2016 to 2022, particularly in how SDF was being taught (97% teaching didactically and clinically vs. 48% in 2016), but were not necessarily a response to the COVID pandemic. Schools report teaching more indications for the use of SDF and using more specific protocols with more schools teaching arresting caries in permanent teeth (97% vs. 78% in 2016). Since 2016, the use and teaching of SDF have been increasingly adopted across U.S. dental schools, though there remains room for improvement in terms of consistent implementation, specific clinical protocols, and comprehensive training.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1466962"},"PeriodicalIF":1.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of a pediatric patient with dental anomalies and its effect on psychosocial status: a case report.
IF 1.5
Frontiers in dental medicine Pub Date : 2025-01-10 eCollection Date: 2024-01-01 DOI: 10.3389/fdmed.2024.1502195
Wesam Damanhouri, Kholoud Moussa, Joudi Bathallath, Zohour Alsomali, Abeer Bakor, Moaz Attar
{"title":"Management of a pediatric patient with dental anomalies and its effect on psychosocial status: a case report.","authors":"Wesam Damanhouri, Kholoud Moussa, Joudi Bathallath, Zohour Alsomali, Abeer Bakor, Moaz Attar","doi":"10.3389/fdmed.2024.1502195","DOIUrl":"10.3389/fdmed.2024.1502195","url":null,"abstract":"<p><p>Managing multiple dental anomalies in the anterior region of the dental arch presents unique and complex challenges. This case report describes using a multidisciplinary approach to manage a child with not only a fused tooth with a supernumerary but also the presence of other supernumerary teeth in the same place. In this case, deviation from the standard management of a fused permanent anterior tooth, an anchor for aesthetics, by extracting it because of crown root complexity and allowing a supernumerary to erupt into its place made the difference in the successful outcome. However, this condition required multidisciplinary management that necessitated the involvement of the psychiatric department. Continuous assessment of the patient's psychosocial function using the Social Avoidance and Distress Scale (SADS) allowed appropriate guidance to manage the patient's behavior. This case report added a different perspective on managing a fused tooth with a supernumerary to the literature. It showed how dental aesthetics can have an adverse effect on children's psychology.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1502195"},"PeriodicalIF":1.5,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797825/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum: Students' perceptions of endodontic typodont teeth with simulated canals printed from novel materials.
IF 1.5
Frontiers in dental medicine Pub Date : 2025-01-07 eCollection Date: 2024-01-01 DOI: 10.3389/fdmed.2024.1547849
Alexander Jon Cresswell-Boyes, Graham Roy Davis, Aylin Baysan
{"title":"Corrigendum: Students' perceptions of endodontic typodont teeth with simulated canals printed from novel materials.","authors":"Alexander Jon Cresswell-Boyes, Graham Roy Davis, Aylin Baysan","doi":"10.3389/fdmed.2024.1547849","DOIUrl":"https://doi.org/10.3389/fdmed.2024.1547849","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.3389/fdmed.2024.1373922.].</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1547849"},"PeriodicalIF":1.5,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Description of the root anatomy of the primary molars using high resolution computed microtomography (Micro-CT). An analysis of three-dimensional root canal system.
IF 1.5
Frontiers in dental medicine Pub Date : 2025-01-06 eCollection Date: 2024-01-01 DOI: 10.3389/fdmed.2024.1522414
Benedetta Vidi, Ana María Gil-Valcarcel, Cristina Obispo-Diaz, Isabel Sanchez-Jorge, Jesús Mena-Álvarez, Juan Manuel Aragoneses-Lamas, Cristina Rico-Romano
{"title":"Description of the root anatomy of the primary molars using high resolution computed microtomography (Micro-CT). An analysis of three-dimensional root canal system.","authors":"Benedetta Vidi, Ana María Gil-Valcarcel, Cristina Obispo-Diaz, Isabel Sanchez-Jorge, Jesús Mena-Álvarez, Juan Manuel Aragoneses-Lamas, Cristina Rico-Romano","doi":"10.3389/fdmed.2024.1522414","DOIUrl":"10.3389/fdmed.2024.1522414","url":null,"abstract":"<p><strong>Background/purpose: </strong>This study aimed to describe the root canal morphology of primary molars using Micro-CT and analyse the three-dimensional images of the internal root canal system.</p><p><strong>Material and methods: </strong>One hundred and twenty extracted primary molars with one or more completed roots were scanned with Micro-CT. Three fixed heights of the roots were determined at axial level and the analysed criteria were: dentine thickness, diameter of roots canals, presence of lateral canals, isthmus and number of foramina. Vertucci's classification was also studied.</p><p><strong>Results: </strong>Vertucci Type I was more prevalent in palatal and mesio-buccal root of superior molar and distal root of inferior molars. Type IV was more frequent in the mesial root. Dentine thickness was studied at three levels and for all the surfaces of the root canal. In the mesiobuccal root, in the middle and apical third, the mean in the upper molars is significantly higher than in the lower molars. The mesio-lingual canal has the major mean in mesio-distal and bucco-lingual diameter at coronal third. Isthmus were found mostly in the mesial root in all three levels. The high number of foramina and lateral canals were located at apical third of the mesial and mesio-buccal roots.</p><p><strong>Conclusion: </strong>This study showed the complexity and variability of the root canal morphology of primary molars. The Micro-CT images gave important information about the internal anatomy of the primary molars.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1522414"},"PeriodicalIF":1.5,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transforming dental diagnostics with artificial intelligence: advanced integration of ChatGPT and large language models for patient care.
IF 1.5
Frontiers in dental medicine Pub Date : 2025-01-06 eCollection Date: 2024-01-01 DOI: 10.3389/fdmed.2024.1456208
Masoumeh Farhadi Nia, Mohsen Ahmadi, Elyas Irankhah
{"title":"Transforming dental diagnostics with artificial intelligence: advanced integration of ChatGPT and large language models for patient care.","authors":"Masoumeh Farhadi Nia, Mohsen Ahmadi, Elyas Irankhah","doi":"10.3389/fdmed.2024.1456208","DOIUrl":"10.3389/fdmed.2024.1456208","url":null,"abstract":"<p><p>Artificial intelligence has dramatically reshaped our interaction with digital technologies, ushering in an era where advancements in AI algorithms and Large Language Models (LLMs) have natural language processing (NLP) systems like ChatGPT. This study delves into the impact of cutting-edge LLMs, notably OpenAI's ChatGPT, on medical diagnostics, with a keen focus on the dental sector. Leveraging publicly accessible datasets, these models augment the diagnostic capabilities of medical professionals, streamline communication between patients and healthcare providers, and enhance the efficiency of clinical procedures. The advent of ChatGPT-4 is poised to make substantial inroads into dental practices, especially in the realm of oral surgery. This paper sheds light on the current landscape and explores potential future research directions in the burgeoning field of LLMs, offering valuable insights for both practitioners and developers. Furthermore, it critically assesses the broad implications and challenges within various sectors, including academia and healthcare, thus mapping out an overview of AI's role in transforming dental diagnostics for enhanced patient care.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1456208"},"PeriodicalIF":1.5,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanosystems for modulation of immune responses in periodontal therapy: a mini-review.
IF 1.5
Frontiers in dental medicine Pub Date : 2025-01-06 eCollection Date: 2024-01-01 DOI: 10.3389/fdmed.2024.1509775
Anirudh B Acharya, Usha Hegde, Swetha Acharya
{"title":"Nanosystems for modulation of immune responses in periodontal therapy: a mini-review.","authors":"Anirudh B Acharya, Usha Hegde, Swetha Acharya","doi":"10.3389/fdmed.2024.1509775","DOIUrl":"10.3389/fdmed.2024.1509775","url":null,"abstract":"<p><p>Periodontitis is one of the most common oral diseases. It is generally treated by non-surgical and/or surgical therapy with adjunctive approaches for prevention and control. The current understanding of the pathogenesis of periodontitis has unraveled the importance of the inflammatory and immune reactions to combat periodontitis whose etiology is an overlap of microbial, genetic, and environmental factors in a susceptible host. Based on this premise, many therapeutic modalities have been investigated or attempted to resolve this inflammatory disease. Amongst these, nanomedicine has been shown to have therapeutic applications in periodontitis, especially focused on immunomodulation because periodontitis is characterized by over-reactive immune response. This mini-review explores the potential of nanosystems in treating periodontitis by providing an overview of the research efforts in this field of therapeutics. The unique physicochemical and targeting properties of nanosystems seem to be potentially effective platforms for treating periodontitis.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1509775"},"PeriodicalIF":1.5,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797770/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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