Frontiers in dental medicine最新文献

{"title":"The impact of estrogen on periodontal tissue integrity and inflammation-a mini review.","authors":"Sucharitha Palanisamy","doi":"10.3389/fdmed.2025.1455755","DOIUrl":"10.3389/fdmed.2025.1455755","url":null,"abstract":"<p><p>Estrogen is said to be a crucial player in different aspects of periodontal health and disease, influencing a spectrum of cellular and molecular processes within periodontal tissues. Its receptors, ERα and ERβ, are expressed in various periodontal cells, suggesting direct responsiveness to hormonal fluctuations. Mechanistically, estrogen regulates osteoblast and osteoclast activity, thereby affecting bone turnover and maintenance of alveolar bone density. Studies indicate that estrogen upregulates the periodontal ligament stem cells' osteogenic differentiation (PDLSCs), promoting collagen synthesis and matrix mineralization critical for periodontal tissue integrity. Moreover, estrogen's anti-inflammatory properties modulate cytokine expression and immune responses in the periodontium, potentially attenuating periodontal inflammation and tissue destruction. Conversely, estrogen deficiency, such as in postmenopausal women, correlates with increased susceptibility to periodontal diseases characterized by greater clinical attachment loss and alveolar bone resorption. Hormone replacement therapy (HRT) with estrogen has shown promise in clinical settings, demonstrating beneficial effects on periodontal health by reducing inflammation and maintaining alveolar bone density. However, the adequacy and assurance of long-term estrogen supplementation in periodontal management require further investigation due to its systemic effects on other tissues and organs. Understanding the intricate interactions between estrogen and periodontal tissues is crucial for developing targeted therapies that leverage hormonal pathways to enhance periodontal health and mitigate disease progression effectively.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1455755"},"PeriodicalIF":1.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Butylboronic acid promotes cell proliferation, alkaline phosphatase activity, and expression of <i>GJA1</i>, <i>ALP</i>, and <i>NaBC1</i> in human dental pulp cells <i>in vitro</i>.","authors":"Takashi Nakano, Hidenori Hamba, Takashi Muramatsu","doi":"10.3389/fdmed.2025.1518389","DOIUrl":"10.3389/fdmed.2025.1518389","url":null,"abstract":"<p><p>The objective of this study is to investigate the effects of n-butylboronic acid (n-BA) on the proliferative activity, alkaline phosphatase activity, expression of hard tissue formation related genes, <i>ALP</i> and <i>GJA1</i>, and boron transporter gene, <i>NaBC1</i>, in human dental pulp cells. Human dental pulp cells were spread in culture medium with n-BA. The proliferative activity was increased in n-BA group. alkaline phosphatase staining and alizarin red S staining identified no obvious differences between the n-BA(+) and n-BA(-) groups. Alkaline phosphatase activity was significantly increased in the n-BA(+) group compared to the n-BA(-) group. Expressions of <i>GJA1</i>, <i>ALP</i>, and <i>NaBC1</i> in the n-BA(+) group were higher than that of the n-BA(-) group. There were no significant differences between NaBC1-shRNA-transfected group and control group about proliferation and alkaline phosphatase activity. The results suggest that n-BA promotes cell proliferation, alkaline phosphatase activity, and expression of <i>GJA1</i>, <i>ALP</i>, and <i>NaBC1</i>, in human dental pulp cells.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1518389"},"PeriodicalIF":1.5,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Additive-manufactured ceramics for dental restorations: a systematic review on mechanical perspective.","authors":"Yuqing Lu, Anouk van Steenoven, Amanda Maria de Oliveira Dal Piva, João Paulo Mendes Tribst, Li Wang, Cornelis J Kleverlaan, Albert J Feilzer","doi":"10.3389/fdmed.2025.1512887","DOIUrl":"10.3389/fdmed.2025.1512887","url":null,"abstract":"<p><strong>Background: </strong>Additive manufacturing (AM) is rapidly expanding as a substitute for conventional heat-pressing and milling techniques for ceramic restorations. However, experimental and clinical evidence on the mechanical properties and performance of the final ceramic products is yet insufficient. This systematic review aimed to update the latest advances in additive manufacturing of restorative ceramics with a focus on their mechanical properties.</p><p><strong>Methods: </strong>This systematic review was structured using the 5-step methodology based on the research question: what are the mechanical properties of additive-manufactured restorative ceramics in comparison with subtractive manufacturing? The electronic literature search was performed independently by 2 authors in the following databases: PubMed/MEDLINE, Web of Science, and Scopus. Published articles from 2019 to 2023 were screened, analysed and the relevant papers were selected for inclusion in this review.</p><p><strong>Results: </strong>A total of 40 studies were included. The available ceramics include zirconia, alumina and alumina-zirconia composites, lithium disilicate, porcelain and fluorapatite glass ceramic. The mechanical properties were summarized according to material and technique: density (15 studies), flexural strength (31 studies), fracture toughness (7 studies), Young's modulus (7 studies), hardness (11 studies) and performance (7 studies). Overall, the properties exhibited an upward trend toward the values of conventional techniques. Typical processing defects, including porosity, agglomerates, cracks, surface roughness, and other defects, were also analyzed.</p><p><strong>Conclusions: </strong>With significant technological advancements, the mechanical properties of AM ceramics have come close to ceramics by conventional manufacturing, whereas their reliability, the influence of printing layer orientations, and long-term performance still need further investigation.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1512887"},"PeriodicalIF":1.5,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiographic localization of supernumerary teeth: a narrative review.","authors":"Sreekanth Kumar Mallineni, Robert Prashanth Anthonappa, Jayakumar Jayaraman, Nigel Martyn King","doi":"10.3389/fdmed.2025.1495025","DOIUrl":"10.3389/fdmed.2025.1495025","url":null,"abstract":"<p><strong>Objectives: </strong>To conduct a narrative review of the published literature on the localization techniques to identify the best technique for the localization of supernumerary teeth.</p><p><strong>Methods: </strong>An extensive search of literature published in English between January 1966 and May 2024 was conducted using the \"Medline via PubMed\" and \"Cochrane database\" databases. The keywords included in the search were \"localization\" \"radiographs\", and \"impacted teeth\", or \"un-erupted teeth\", or \"supernumerary teeth\" or \"supernumerary tooth\". The citation lists from the included articles were examined to identify additional reports and a hand search was also conducted. Kappa statistics were used for intra-examiner reliability.</p><p><strong>Results: </strong>The initial search yielded 4,864 citations, subsequently examined and supplemented by a hand search to find additional studies. Commonly used techniques for the localization of supernumerary teeth are the horizontal tube shift technique, vertical tube shift technique, vertex occlusal technique, and cone-beam computerized tomography.</p><p><strong>Conclusion: </strong>The most commonly used localization techniques for supernumerary teeth are horizontal tube shift, vertex occlusal, vertical tube shift, and cone-beam computerized tomography. Conventional radiographs only provide two-dimensional views of 3-dimensional structures. Three-dimensional imaging alone can provide accurate data on impacted supernumerary teeth but, the need for this film has to be justified because of the higher radiation exposure.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1495025"},"PeriodicalIF":1.5,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apical periodontitis in inflammatory bowel disease: a meta-analysis at patient and tooth level.","authors":"Giusy Rita Maria La Rosa, Alejandro Ismael Lorenzo-Pouso, Vito Carlo Alberto Caponio, Mariangela Valentina Puci","doi":"10.3389/fdmed.2025.1553914","DOIUrl":"10.3389/fdmed.2025.1553914","url":null,"abstract":"<p><p>Apical periodontitis (AP) is the local inflammation of periapical tissues originating from the dental pulp disease. Cumulative evidence suggests a link between oral and gastro-intestinal systems in both health and disease. In this context, the relationship between AP and inflammatory bowel diseases (IBDs) has not yet been elucidated. The aims of this systematic review and meta-analysis were to describe the prevalence of AP in patients with IBDs and evaluate the potential association between AP and IBDs. Electronic (Embase, PubMed, Scopus, Web of Science) and manual literature searches were conducted from inception to 31 October, 2023 (updated in August, 2024). Strict inclusion criteria were applied to identify observational and experimental clinical studies on AP in IBDs patients. The bias risk was assessed using the Joanna Briggs Institute critical appraisal tools and a biases' report selected from the Oxford Centre for Evidence Based Medicine Catalogue of Bias. A meta-analysis was performed to determine the pooled prevalence and risk of AP at individual and tooth level and the quality of evidence was assessed by the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. The search strategy identified 82 articles with 5 studies included (657 subjects, 7,142 teeth). The overall proportion of AP was 58% at patient level (95% CI = 37%-78%, <i>I</i> ² = 95.3%) and 7% at tooth level (95% CI = 2%-15%; <i>I</i> ² = 99.2%). AP was prevalent in IBDs subjects than in healthy controls, both at patient and tooth level. The pooled OR was 1.57 (95% CI = 1.04-2.35; <i>P</i> = 0.038; <i>I</i> ² = 20%) at patient level, and 1.91 (95% CI = 1.16-3.15; <i>P</i> = 0.011; <i>I</i> ² = 82%) at tooth level. A potential association between AP and IBDs is plausible, although the quality evidence was low to very low. Longitudinal and experimental studies should be conducted to better understand the relationship between these two conditions and explore any potential causative factors.</p><p><strong>Systematic review registration: </strong>https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=411038, PROSPERO (CRD42023411038).</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1553914"},"PeriodicalIF":1.5,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of root resorption on lateral incisors after primary canine extraction treating mesioangular displaced permanent canines: a randomised controlled trial.","authors":"Narmin Helal, Reem Naaman, Najlaa Alamoudi, Azza El-Housseiny, Fatima Jadu","doi":"10.3389/fdmed.2024.1456985","DOIUrl":"10.3389/fdmed.2024.1456985","url":null,"abstract":"<p><strong>Aim: </strong>Root resorption (RR) of the adjacent maxillary lateral incisors is considered the most common complication of displaced maxillary canines. The aim of this study was to assess the effect of interceptive extraction of the primary canines on the condition of the roots of permanent neighbouring teeth to mesioangular displaced canines (MDC). In addition, this study aimed to investigate the relationship between the position of the unerupted canine and the risk of RR in adjacent lateral incisors.</p><p><strong>Design: </strong>Randomised controlled clinical trial.</p><p><strong>Methods: </strong>Eighty-five patients 9-12-year-old with MDC were allocated equally to either an extraction group (EG) or a control group (CG). Of the sample, 33 were males (38.8%), and 52 were females (61.2%). Among this sample, 81 canines (51.9%) were buccally displaced, 34 canines (21.8%) were palatally displaced, and 41 canines (26.3%) were mid-alveolar. All subjects underwent cone-beam computed tomography examination to determine the presence, stage, and level of lateral incisor root resorption (RR). Measurements were performed at T0 and repeated at a 12-month follow-up (T2).</p><p><strong>Results & statistics: </strong>Root resorption (RR) was present in 28.2% of lateral incisors at the baseline assessment (T0) and exhibited a significant increase at the 12-month follow-up (T12). This marked increase in resorption severity was evident between T0 and T12 (<i>P</i> = 0007), regardless of group allocation. There was a significant increase in the degree of resorption between T2 and T0, with a mean difference equals to 0.31 (0.73), <i>P</i> < 0.0001. While there was no statistically significant difference in resorption levels between the extraction and control groups at T0 (<i>P</i> = 0.11), RR occurred more frequently with midalveolar (34.1%) and palatal (32.3%) displacements than with buccal displacements (23.5%). Severe resorption was observed more frequently in cases involving palatally displaced canines within both groups, but it did not reach statistical significance.</p><p><strong>Conclusions: </strong>Lateral incisor root resorption (RR) progressed significantly within a 12-month period irrespective of treatment modality. RR occurred more frequently with midalveolar and palatal displacement with a trend towards increased RR severity in cases with palatally displaced canines. Early clinical evaluation and consistent monitoring is essential for early detection and potential intervention in patients with mesioangular canine displacement.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1456985"},"PeriodicalIF":1.5,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial activity of biodentine against <i>Enterococcus faecalis</i>: a systematic review.","authors":"Hasan Subhi, Nashwah Subhi, Salah Alhaidary, Mahmood S Azeez, Abedelmalek Kalefh Tabnjh","doi":"10.3389/fdmed.2024.1498353","DOIUrl":"10.3389/fdmed.2024.1498353","url":null,"abstract":"<p><strong>Introduction: </strong>Biodentine is a well-known endodontic material that is applied in various endodontic therapies. <i>Enterococcus faecalis</i> (<i>E. faecalis</i>) is associated with endodontic failure and persistent periapical infection. The purpose of this systematic review was to summarize the available evidence regarding the antibacterial activity of Biodentine against <i>E. faecalis</i> and to compare it to other commercial endodontic materials.</p><p><strong>Methods: </strong>An electronic search of literature was conducted in PubMed, Scopus, Web of Science, and Google Scholar in addition to a manual search in specialized journals up to May 2024. The eligibility criteria, data extraction, and evaluation of risk of bias were assessed by two independent authors. The risk of bias was evaluated in accordance with Modified CONSORT checklist items for pre-clinical in vitro studies on dental materials.</p><p><strong>Results: </strong>Out of 343 studies, thirty-seven fulfilled the inclusion criteria and were included in this review. Thirty studies reported a good antibacterial efficacy of Biodentine against <i>E. faecalis</i>. Biodentine was superior to or, at least, as efficacious as MTA, MTA Angelus, GIC, RMGIC, DiaRoot BioAggregate, NeoPutty, iRoot FS, MTA Repair HP, MTA Biorep, Well-Root PT, Activa, NeoMTA 2, Calcimol LC, TotalFill, and IRM. The findings were supported by studies with medium to high risk of bias (low quality).</p><p><strong>Conclusions: </strong>Considering the limitations of this systematic review, there is accumulating evidence on the antibacterial activity of Biodentine against <i>E. faecalis</i> in context of endodontics. However, randomized clinical trials with well-designed and robust methodologies are required in order to provide information about its clinical behaviour.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1498353"},"PeriodicalIF":1.5,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Family factors associated with dental caries among 5-year-old preschool children.","authors":"Giovanna Torqueto Castilho, Marília Narducci Pessoa, Caroline Correa de Oliveira, Letícia Santos Alves de Melo, Elaine Pereira Silva Tagliaferro, Vanessa Pardi","doi":"10.3389/fdmed.2024.1473194","DOIUrl":"10.3389/fdmed.2024.1473194","url":null,"abstract":"<p><strong>Background: </strong>Although dental caries is largely preventable, it remains highly prevalent among children.</p><p><strong>Aim: </strong>Evaluate family factors associated with the prevalence of dental caries in 5-year-old children.</p><p><strong>Design: </strong>This cross-sectional study recruited 5-year-old children from public preschools in Araraquara, São Paulo, Brazil. Data on sociodemographic factors, family routines, and oral health practices were gathered via a self-administered questionnaire completed independently by caregivers. Children received a dental clinical examination at school and caries experience was recorded using the dmft and SiC (Significant Caries index) indexes following the World Health Organization (WHO) criteria.</p><p><strong>Results: </strong>Data analysis was performed using Chi-square and multiple logistic regression using a significance level of 5%. Of the 578 children in the study, 67.3% were caries-free. The mean dmft index was 1.14 (SD = 2.24), while the SiC index stood at 3.46 (2.69). Factors such as income, caregiver assistance with toothbrushing, caregiver perception of child and parent oral health, and prioritization of dental visits within the family were associated with caries presence.</p><p><strong>Conclusions: </strong>Overall, dental caries prevalence was low in this population, with family factors demonstrating significant associations with dental caries. The attitudes of caregivers regarding oral health appear to wield considerable influence over the dental health of their children.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1473194"},"PeriodicalIF":1.5,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interdental papilla recession and reconstruction of the lost triangle: a review of the current literature.","authors":"Sanabel O Barakat","doi":"10.3389/fdmed.2024.1537452","DOIUrl":"10.3389/fdmed.2024.1537452","url":null,"abstract":"<p><p>Interdental papilla (IDP) deficiency and the presence of gingival black triangles (GBT) are major concerns for both patients and dentists, as the IDP plays an important role in esthetics due to its strong association with the patient's smile. Interdental papilla deficiency is frequent among different populations, with a tendency to increase with age and in patients with periodontal disease. In addition, GBT causes phonetic problems, food impaction, plaque accumulation, and increased risk for root caries. The small dimensions of the IDP and the limited vascular supply to the interproximal space render treatment modalities of receded papillae unpredictable. Still, and based on the etiological factors, several non-surgical treatment options, including correction of traumatic oral hygiene practices, restorative interventions, papilla priming, papilla enhancement with either autologous fibroblast injection or hyaluronic acid, and orthodontic therapy, have been proposed to fill the GBT. In addition, different surgical techniques-with or without grafting biomaterials-have also been introduced to reconstruct the lost papilla. Nonetheless, there is no gold standard set yet. Further, systematic reviews evaluating the efficacy of surgical reconstruction of deficient IDP are still lacking due to the scarcity of large-scale clinical trials and the absence of long-term clinical outcomes. The aim of this review was to identify various causes of IDP recession as well as to explore the available treatment modalities to reconstruct the lost papilla.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1537452"},"PeriodicalIF":1.5,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An updated look at the use of silver diamine fluoride in U.S. dental schools' predoctoral curriculum-a survey.","authors":"Benas Jakubauskas, Sarah Pagni, Andrea G Ferreira Zandona","doi":"10.3389/fdmed.2024.1466962","DOIUrl":"10.3389/fdmed.2024.1466962","url":null,"abstract":"<p><p>This survey aimed to update Silver Diamine Fluoride (SDF) use/teaching in U.S. predoctoral dental education programs in comparison to a 2016 survey, considering the COVID-19 pandemic. An online survey via email was sent to all accredited U.S. predoctoral dental education programs (<i>n</i> = 68) in January 2022. A total of 39 schools (57% response rate) responded to the survey, and all 39 of them reported that SDF was now part of their curriculum, significantly different (<i>p</i> < 0.001) from 2016 (68% of schools). Significant changes (<i>p</i> < 0.001) were reported in the survey responses from 2016 to 2022, particularly in how SDF was being taught (97% teaching didactically and clinically vs. 48% in 2016), but were not necessarily a response to the COVID pandemic. Schools report teaching more indications for the use of SDF and using more specific protocols with more schools teaching arresting caries in permanent teeth (97% vs. 78% in 2016). Since 2016, the use and teaching of SDF have been increasingly adopted across U.S. dental schools, though there remains room for improvement in terms of consistent implementation, specific clinical protocols, and comprehensive training.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"5 ","pages":"1466962"},"PeriodicalIF":1.5,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11797966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}