{"title":"The effects of magnesium-containing coatings on the healing of soft tissues surrounding oral titanium abutments: a narrative review.","authors":"Hongya Zheng, Chenxi Shang, Ping Li, Wenjie Zhao, Yumei Niu, Shuang Pan, Shuang Zhang","doi":"10.3389/fdmed.2025.1638027","DOIUrl":null,"url":null,"abstract":"<p><p>The inherent limitations of smooth titanium abutments-particularly inadequate soft tissue sealing that predisposes implants to infection and inflammation-underscore the need for surface modifications. This review synthesizes evidence on magnesium-containing coatings as a bioactive solution to enhance peri-implant soft tissue healing. Through 1) modifying the surface properties of the implant abutment to promote better cell adhesion and proliferation; 2) releasing Mg<sup>2+</sup> to promote fibroblast migration, collagen synthesis, and angiogenesis; and 3) exerting antimicrobial effects and regulating inflammatory responses, these coatings establish a microenvironment conducive to robust tissue integration. This helps prevent peri-implant infections and inflammation, strengthens soft tissue attachment, and improves the long-term stability of dental implants, providing a new direction for the development of biomedical materials.</p>","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":"6 ","pages":"1638027"},"PeriodicalIF":1.8000,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12507913/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in dental medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3389/fdmed.2025.1638027","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
引用次数: 0
Abstract
The inherent limitations of smooth titanium abutments-particularly inadequate soft tissue sealing that predisposes implants to infection and inflammation-underscore the need for surface modifications. This review synthesizes evidence on magnesium-containing coatings as a bioactive solution to enhance peri-implant soft tissue healing. Through 1) modifying the surface properties of the implant abutment to promote better cell adhesion and proliferation; 2) releasing Mg2+ to promote fibroblast migration, collagen synthesis, and angiogenesis; and 3) exerting antimicrobial effects and regulating inflammatory responses, these coatings establish a microenvironment conducive to robust tissue integration. This helps prevent peri-implant infections and inflammation, strengthens soft tissue attachment, and improves the long-term stability of dental implants, providing a new direction for the development of biomedical materials.