Frontiers in dental medicine最新文献_第6页

Artificial intelligence in dentistry—A review 人工智能在牙科中的应用综述

Frontiers in dental medicine Pub Date : 2023-02-20 DOI: 10.3389/fdmed.2023.1085251

H. Ding, Jiamin Wu, Wuyuan Zhao, J. Matinlinna, M. Burrow, J. Tsoi

{"title":"Artificial intelligence in dentistry—A review","authors":"H. Ding, Jiamin Wu, Wuyuan Zhao, J. Matinlinna, M. Burrow, J. Tsoi","doi":"10.3389/fdmed.2023.1085251","DOIUrl":"https://doi.org/10.3389/fdmed.2023.1085251","url":null,"abstract":"Artificial Intelligence (AI) is the ability of machines to perform tasks that normally require human intelligence. AI is not a new term, the concept of AI can be dated back to 1950. However, it has not become a practical tool until two decades ago. Owing to the rapid development of three cornerstones of current AI technology—big data (coming through digital devices), computational power, and AI algorithm—in the past two decades, AI applications have been started to provide convenience to people's lives. In dentistry, AI has been adopted in all dental disciplines, i.e., operative dentistry, periodontics, orthodontics, oral and maxillofacial surgery, and prosthodontics. The majority of the AI applications in dentistry go to the diagnosis based on radiographic or optical images, while other tasks are not as applicable as image-based tasks mainly due to the constraints of data availability, data uniformity, and computational power for handling 3D data. Evidence-based dentistry (EBD) is regarded as the gold standard for the decision-making of dental professionals, while AI machine learning (ML) models learn from human expertise. ML can be seen as another valuable tool to assist dental professionals in multiple stages of clinical cases. This review narrated the history and classification of AI, summarised AI applications in dentistry, discussed the relationship between EBD and ML, and aimed to help dental professionals to understand AI as a tool better to assist their routine work with improved efficiency.","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48473302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Insight into the development of versatile dentin bonding agents to increase the durability of the bonding interface 深入了解多功能牙本质粘结剂的开发，以提高粘结界面的耐久性

Frontiers in dental medicine Pub Date : 2023-02-16 DOI: 10.3389/fdmed.2023.1127368

I. Porto, Teresa de Lisieux Guedes Ferreira Lôbo, R. Rodrigues, R. Lins, Marcos Aurélio Bomfim da Silva

{"title":"Insight into the development of versatile dentin bonding agents to increase the durability of the bonding interface","authors":"I. Porto, Teresa de Lisieux Guedes Ferreira Lôbo, R. Rodrigues, R. Lins, Marcos Aurélio Bomfim da Silva","doi":"10.3389/fdmed.2023.1127368","DOIUrl":"https://doi.org/10.3389/fdmed.2023.1127368","url":null,"abstract":"Despite the huge improvements made in adhesive technology over the past 50 years, there are still some unresolved issues regarding the durability of the adhesive interface. A complete sealing of the interface between the resin and the dentin substrate remains difficult to achieve, and it is doubtful whether an optimal interdiffusion of the adhesive system within the demineralized collagen framework can be produced in a complete and homogeneous way. In fact, it is suggested that hydrolytic degradation, combined with the action of dentin matrix enzymes, destabilizes the tooth-adhesive bond and disrupts the unprotected collagen fibrils. While a sufficient resin–dentin adhesion is usually achieved immediately, bonding efficiency declines over time. Thus, here, a review will be carried out through a bibliographic survey of scientific articles published in the last few years to present strategies that have been proposed to improve and/or develop new adhesive systems that can help prevent degradation at the adhesive interface. It will specially focus on new clinical techniques or new materials with characteristics that contribute to increasing the durability of adhesive restorations and avoiding the recurrent replacement restorative cycle and the consequent increase in damage to the tooth.","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46842566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of the soluble epoxide hydrolase cascade on periodontal tissues 可溶性环氧化物水解酶级联反应对牙周组织的影响

Frontiers in dental medicine Pub Date : 2023-02-01 DOI: 10.3389/fdmed.2023.1129371

H. Abdalla, T. V. Van Dyke

{"title":"The impact of the soluble epoxide hydrolase cascade on periodontal tissues","authors":"H. Abdalla, T. V. Van Dyke","doi":"10.3389/fdmed.2023.1129371","DOIUrl":"https://doi.org/10.3389/fdmed.2023.1129371","url":null,"abstract":"Periodontitis is a chronic inflammatory disease with complex pathogenesis. Uncontrolled inflammation is driven by the immune system in response to accumulation of oral biofilm that leads to alveolar bone loss, bleeding, increased periodontal probing depth with loss of attachment of the connective tissues to the tooth, and ultimately, tooth loss. Soluble epoxide hydrolase (sEH) is an enzyme that converts epoxy fatty acids (EpFAs) produced by cytochrome P450 (CYP450) to an inactive diol. It has been shown that EpFAs display important features to counteract an exaggerated inflammatory process. Based upon this observation, inhibitors of sEH have been developed and are being proposed as a strategy to regulate proinflammatory inflammatory lipid mediator production and the chronicity of inflammation. This mini review focuses on the impact of sEH inhibition on periodontal tissues focusing on the mechanisms involved. The interaction between Specialized Pro-Resolving Mediators and sEH inhibition emerges as a significant mechanism of action of sEH inhibitors that was not formerly appreciated and provides new insight into the role SPMs may play in prevention and treatment of periodontitis.","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49317327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Classical trigeminal neuralgia is associated with gephyrin and sodium voltage-gated channel alpha subunit 8 经典三叉神经痛与酞酸钠电压门控通道α亚基8有关

Frontiers in dental medicine Pub Date : 2023-01-30 DOI: 10.3389/fdmed.2022.988094

A. Vieira, R. Sekula, K. Deeley

{"title":"Classical trigeminal neuralgia is associated with gephyrin and sodium voltage-gated channel alpha subunit 8","authors":"A. Vieira, R. Sekula, K. Deeley","doi":"10.3389/fdmed.2022.988094","DOIUrl":"https://doi.org/10.3389/fdmed.2022.988094","url":null,"abstract":"Trigeminal neuralgia is highly debilitating, and its etiology is still undefined. The goal of this work was to define associations between well-characterized trigeminal neuralgia cases and common genetic variants in the population. two hundred and fifty-seven individuals diagnosed with classical trigeminal neuralgia were compared to 865 individuals without classical trigeminal neuralgia and with an assessment for lower or higher pain threshold based on the amount of anesthetic required for routine dental treatment. Genotypes of 24 variants marking genes in the VGSC (voltage-gated sodium channels) or GABA (gamma-aminobutyric acid) pathways were obtained using TaqMan chemistry end end-point analysis. Chi-square was used for all comparisons with an alpha of 0.002. An association between classical trigeminal neuralgia and individuals requiring less or more anesthetic for routine dental treatments showed associations with SCN8A rs1601012 and GPHN rs723432 (p = 0.0009 and p = 0.0002, respectively). In conclusion, classical trigeminal neuralgia is associated with SCN8A and GPHN and markers rs1601012 rs723432 may be useful to determine individual risks for the condition.","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86732272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Materials informatics for developing new restorative dental materials: A narrative review 材料信息学用于开发新的牙科修复材料:述评

Frontiers in dental medicine Pub Date : 2023-01-26 DOI: 10.3389/fdmed.2023.1123976

S. Yamaguchi, Hefei Li, S. Imazato

引用次数: 1

Mechanical test relevance—A personal perspective on some methods and requirements 机械测试相关性——从个人角度看待一些方法和要求

Frontiers in dental medicine Pub Date : 2023-01-23 DOI: 10.3389/fdmed.2022.1084006

B. Darvell

引用次数: 1

Microbiome, alveolar bone, and metabolites: Connecting the dots 微生物组，牙槽骨和代谢物:连接点

Frontiers in dental medicine Pub Date : 2023-01-10 DOI: 10.3389/fdmed.2022.1074339

David Fraser, S. Ganesan

{"title":"Microbiome, alveolar bone, and metabolites: Connecting the dots","authors":"David Fraser, S. Ganesan","doi":"10.3389/fdmed.2022.1074339","DOIUrl":"https://doi.org/10.3389/fdmed.2022.1074339","url":null,"abstract":"The oral microbiome (OM) is a diverse and dynamic collection of species, separated from alveolar bone by the oral mucosa. Pathogenic shifts in the OM (dysbiosis) during periodontitis are associated with an inflammatory response in the oral mucosa that drives alveolar bone resorption. Alveolar bone is also affected by metabolic disorders such as osteoporosis. Accumulating evidence has linked another microbial community, the gut microbiome (GM), to systemic bone metabolism and osteoporosis. Underlying this connection is the biologic activity of metabolites, byproducts of host and bacterial activity. Limited evidence also suggests that metabolites in the oral cavity signal between the OM and immune system, influencing both alveolar bone homeostasis and pathologic bone destruction in periodontitis. While the oral cavity and gut are connected through the gastrointestinal tract, dissimilar roles for known metabolites between these two niches exemplify the difficulty in translating knowledge on gut-derived metabolites and bone metabolism to alveolar bone. Integrated metabolomic, transcriptomic, and metagenomic approaches hold promise for resolving these challenges and identifying novel metabolites which impact alveolar bone health. Further interrogation through mechanistic testing in pre-clinical models and carefully controlled clinical studies have potential to lead toward translation of these discoveries into meaningful therapies.","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41333767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral-systemic immune axis: Crosstalk controlling health and disease 口腔-全身免疫轴:控制健康和疾病的串扰

Frontiers in dental medicine Pub Date : 2023-01-09 DOI: 10.3389/fdmed.2022.1106456

N. Lumelsky

引用次数: 0

Applications of regenerative techniques in adult orthodontics 再生技术在成人正畸中的应用

Frontiers in dental medicine Pub Date : 2023-01-09 DOI: 10.3389/fdmed.2022.1100548

Catherine Liu, P. Sharpe, A. Volponi

{"title":"Applications of regenerative techniques in adult orthodontics","authors":"Catherine Liu, P. Sharpe, A. Volponi","doi":"10.3389/fdmed.2022.1100548","DOIUrl":"https://doi.org/10.3389/fdmed.2022.1100548","url":null,"abstract":"Management of the growing adult orthodontic patient population must contend with challenges particular to orthodontic treatment in adults. These include a limited rate of tooth movement, increased incidence of periodontal complications, higher risk of iatrogenic root resorption and pulp devitalisation, resorbed edentulous ridges, and lack of growth potential. The field of regenerative dentistry has evolved numerous methods of manipulating cellular and molecular processes to rebuild functional oral and dental tissues, and research continues to advance our understanding of stem cells, signalling factors that stimulate repair and extracellular scaffold interactions for the purposes of tissue engineering. We discuss recent findings in the literature to synthesise our understanding of current and prospective approaches based on biological repair that have the potential to improve orthodontic treatment outcomes in adult patients. Methods such as mesenchymal stem cell transplantation, biomimetic scaffold manipulation, and growth factor control may be employed to overcome the challenges described above, thereby reducing adverse sequelae and improving orthodontic treatment outcomes in adult patients. The overarching goal of such research is to eventually translate these regenerative techniques into clinical practice, and establish a new gold standard of safe, effective, autologous therapies.","PeriodicalId":73077,"journal":{"name":"Frontiers in dental medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41824108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Integrated manufacturing of direct 3D-printed clear aligners 集成制造直接3d打印清晰对准器

Frontiers in dental medicine Pub Date : 2023-01-06 DOI: 10.3389/fdmed.2022.1089627

Abirami Rajasekaran, P. Chaudhari

引用次数: 2