Analysis & sensing最新文献_第4页

Electrophoretic NMR in Aqueous Systems: Addressing Practical Aspects in Probehead Design and Data Processing 电泳核磁共振在水系统：解决探头设计和数据处理的实际问题

IF 3.3

Analysis & sensing Pub Date : 2026-07-24 DOI: 10.1002/anse.70101

Benjamin Kohn, Sascha Bartosch, Ulrich Scheler

{"title":"Electrophoretic NMR in Aqueous Systems: Addressing Practical Aspects in Probehead Design and Data Processing","authors":"Benjamin Kohn, Sascha Bartosch, Ulrich Scheler","doi":"10.1002/anse.70101","DOIUrl":"https://doi.org/10.1002/anse.70101","url":null,"abstract":"Electrophoretic NMR combines pulsed-field gradient NMR with in situ DC electrophoresis to measure the electrophoretic mobility of individual molecular species in solution, resolved by their chemical shift. While the technique has found broad application in concentrated ionic systems, its application to dilute aqueous systems for the study of polyelectrolytes, proteins, and complexes poses distinct practical challenges. We describe the design and evolution of dedicated E-NMR probeheads optimized for aqueous media. The experiment is implemented as a constant-gradient, constant-time pulsed-field gradient spin echo sequence in which electrophoretic motion appears as a pure phase modulation, cleanly separable from the amplitude attenuation caused by diffusion. For data processing, a modified States-type two-dimensional Fourier transform is applied to data acquired with alternating electric field polarity, yielding phase-sensitive mobility-ordered spectroscopy (MOSY) spectra without requiring prior knowledge of the number of mobile species—a critical advantage for polydisperse or multicomponent systems at low concentration. Practical considerations including Joule heating, voltage/current monitoring, and synchronization of the electric field to the NMR pulse sequence are discussed. The approach is demonstrated in the quantitative analysis of counterion condensation on polyelectrolytes, from which the effective molecular charge is obtained via a combination of diffusion coefficient and electrophoretic mobility measurements.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 4","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.70101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148615655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

129Xe Nuclear Magnetic Resonance Spectroscopy of Metal–Organic Frameworks 金属-有机骨架的129Xe核磁共振波谱

IF 3.3

Analysis & sensing Pub Date : 2026-07-16 DOI: 10.1002/anse.70098

Tobias Bode, Eike Brunner

{"title":"129Xe Nuclear Magnetic Resonance Spectroscopy of Metal–Organic Frameworks","authors":"Tobias Bode, Eike Brunner","doi":"10.1002/anse.70098","DOIUrl":"https://doi.org/10.1002/anse.70098","url":null,"abstract":"129Xe nuclear magnetic resonance (NMR) spectroscopy is a powerful tool for the investigation of various porous materials, for example, zeolites, metal–organic frameworks (MOFs), and covalent organic frameworks. Structure determination of MOFs usually relies on diffraction methods. NMR spectroscopy is complementary to the long-range information provided by diffraction techniques since it relies on the exploitation of short-range interactions without the need for long-range order. This allows, for example, the study of interactions of MOFs with guest atoms as well as structural transitions initiated by adsorbed molecules. For such purposes, 129Xe is a well-suited, inert NMR probe atom that sensitively reflects host–guest interactions. This is due to its high sensitivity to alterations in its close environment, e.g., interactions caused by xenon adsorption inside the cavities of a porous material. The present review introduces the basic properties and possibilities of 129Xe NMR in porous materials and is focused on recent achievements in the field of metal–organic frameworks. Different experimental techniques, including their respective possibilities and limitations, as well as their application to specific research questions like framework flexibility and adsorption selectivity, are presented.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 4","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.70098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148467366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemical Biosensors for the Detection of Carbendazim in Water Sources 水源中多菌灵的电化学生物传感器检测

IF 3.3

Analysis & sensing Pub Date : 2026-07-16 DOI: 10.1002/anse.202500239

Hossein Khosropour, Mansoureh Keramat, Wanida Laiwattanapaisal

{"title":"Electrochemical Biosensors for the Detection of Carbendazim in Water Sources","authors":"Hossein Khosropour, Mansoureh Keramat, Wanida Laiwattanapaisal","doi":"10.1002/anse.202500239","DOIUrl":"https://doi.org/10.1002/anse.202500239","url":null,"abstract":"The industrialization of agriculture has led to a significant exploitation of pesticides and fungicides worldwide. Carbendazim (CBZ), one of the common fungicides used in farming, forestry, and aquaculture, has been criticized for causing environmental contamination, i.e., leaving behind persistent residues in the environment. The development of ultrasensitive technologies for CBZ detection is necessary to ensure food/drinking water safety and to comply with environmental requirements. Due to the high sensitivity, rapid response, simple instrumentation, and ease of operation, the development of electrochemical (bio)sensors for various molecular targets has become increasingly popular in the past two decades. Together with the use of low-cost and portable carbon electrodes (e.g., glassy carbon, screen-printed carbon) makes electrochemical biosensors ideal for on-site and real-time water quality monitoring. Direct electrochemical sensing of CBZ based on its oxidation redox current has been widely studied, with improved performance achieved by modifying electrodes. In the meantime, the discovery of highly specific CBZ aptamers (nucleic acid receptors) from in vitro selections enabled the development of electrochemical “aptasensors” with much improved sensitivity and selectivity. We have critically reviewed the recent developments in electrochemical CBZ sensing since 2021, aiming to connect material characteristics and detection techniques with sensing performance. We discussed direct electrochemical sensing mechanisms, followed by a classification of nanomaterial-modified electrodes based on their dominant functional roles (e.g., conductivity enhancement, electrocatalysis, and adsorption). Finally, advanced molecular recognition-based strategies, including MIP and aptamer-based systems, were presented to highlight selectivity-driven sensor design.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 4","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148467327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiscale Theoretical Calculations Drive Mechanism Analysis and Application Expansion of Nanopore Detection 多尺度理论计算驱动纳米孔检测机理分析及应用拓展

IF 3.3

Analysis & sensing Pub Date : 2026-07-09 DOI: 10.1002/anse.202600002

Dongdong Wang, Xinjia Zhao, Minmin Li, Jiarong Zhang, Yingying Lian, Guangyan Qing

{"title":"Multiscale Theoretical Calculations Drive Mechanism Analysis and Application Expansion of Nanopore Detection","authors":"Dongdong Wang, Xinjia Zhao, Minmin Li, Jiarong Zhang, Yingying Lian, Guangyan Qing","doi":"10.1002/anse.202600002","DOIUrl":"https://doi.org/10.1002/anse.202600002","url":null,"abstract":"Nanopore detection technology has broad application prospects in DNA, protein, and glycan sequencing, as well as in the highly sensitive detection and identification of bio-molecules. However, precise analysis of the structure-function relationship and targeted optimization of device performance remain key bottlenecks restricting further development. Computational simulations can not only explain and verify experimental phenomena but also potentially guide experimental design, shorten the research cycle, and reduce research costs. Therefore, this review comprehensively summarizes the application of multiscale computational calculations in nanopore systems. By incorporating quantum mechanics calculations, molecular docking, molecular dynamics simulations, and finite element analysis, we aim to provide theoretical support for addressing the aforementioned bottlenecks. Among these methods, atomic-scale calculations enable the precise characterization of molecular conformations and intermolecular interactions, thereby clarifying the nanopores’ microscale recognition mechanisms. Mesoscale simulations can trace the analyte translocation dynamics across nanopores, revealing inherent regulatory principles. Macroscale models effectively simulate the hydrodynamic behaviors of nanopore devices. In summary, the synergistic application of multiscale computational simulations establishes theoretical foundation for improving nanopore sensor performance. Furthermore, we discuss the challenges and future trends associated with the synergistic integration of computational simulations, aiming to provide valuable insights for researchers active in computational chemistry and nanopore-based fields.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 4","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148466946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Photo-Responsive Iron-Based Magnetic Resonance Imaging Contrast Agent With Redox Activity 具有氧化还原活性的光响应性铁基磁共振成像造影剂

IF 3.3

Analysis & sensing Pub Date : 2026-07-05 DOI: 10.1002/anse.70102

Zulu Yang, Yanhui Guo, Zhiyuan Yin, Yingying Ning

{"title":"A Photo-Responsive Iron-Based Magnetic Resonance Imaging Contrast Agent With Redox Activity","authors":"Zulu Yang, Yanhui Guo, Zhiyuan Yin, Yingying Ning","doi":"10.1002/anse.70102","DOIUrl":"https://doi.org/10.1002/anse.70102","url":null,"abstract":"Detecting light signals in vivo is highly challenging, and safety concerns associated with gadolinium-based photo-responsive contrast agents have driven the need for safer alternatives. Here we developed a photo-responsive iron-based magnetic resonance imaging (MRI) contrast agent that integrates redox-switchable and photoactivatable mechanisms. The probe features an FeIII center coordinated to a xanthene-based photocage. The probe shows high stability and longitudinal relaxivity (r1 = 2.6 mM−1·s−1). Photoirradiation triggers photodecarboxylation of the xanthene moiety, liberating the carboxyl coordination site and increasing the hydration number of the FeIII center. The product was unstable and gradually decomposed to release Fe3+, further enhancing the r1 to 3.3 mM−1·s−1. Importantly, the complex can convert to its FeII form upon reduction by L-cysteine, exhibiting a substantially diminished r1 of 0.10 mM−1·s−1. Upon simultaneous exposure to light and oxygen, the r1 of the FeII complex increased from 0.1 to 3.3 mM−1·s−1. This dual-responsive strategy achieves a substantial relaxivity change from a low baseline to a high final value. It enables effective contrast enhancement with minimal background and offers a new paradigm for the development of smart MRI probes.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 4","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148462796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diamagnetically Levitated Sensing Platforms Made With Surface-Insulated and Magnetically Aligned Graphite Particles 用表面绝缘和磁排列石墨颗粒制成的抗磁悬浮传感平台

IF 3.3

Analysis & sensing Pub Date : 2026-07-02 DOI: 10.1002/anse.70099

Tomoya Kamide, Ayuto Tatsubo, Jason Twamley, Kazuyuki Takeda

引用次数: 0

Rapid Dual-Mode Detection of Congo Red Using Silver Nanoparticles-Decorated Red Carbon Dot Films for Food Safety Applications 纳米银修饰红碳点薄膜快速双模检测刚果红在食品安全中的应用

IF 3.3

Analysis & sensing Pub Date : 2026-07-02 DOI: 10.1002/anse.70100

A. Joel Amalan, Anitha Pius

{"title":"Rapid Dual-Mode Detection of Congo Red Using Silver Nanoparticles-Decorated Red Carbon Dot Films for Food Safety Applications","authors":"A. Joel Amalan, Anitha Pius","doi":"10.1002/anse.70100","DOIUrl":"https://doi.org/10.1002/anse.70100","url":null,"abstract":"The illegal adulteration of foods with Congo Red (CR) poses significant health risks, necessitating rapid and reliable detection strategies. Herein, we report a dual-mode optical sensing film based on ethylenediamine-mediated silver nanoparticles-decorated red carbon dots embedded in carboxymethyl cellulose (EDA–AgNPs@RCDs/CMC) for selective CR detection. The nanocomposite displayed bright yellow emission at 556 nm (λex = 420 nm), which was efficiently quenched and redshifted via the inner filter effect, π–π stacking, and surface interaction with CR. The probe achieved limits of detection of 0.416 µM (fluorimetry) and 0.439 µM (colorimetry), with rapid response within 2 min under ambient conditions and high stability toward ionic strength and storage. Smartphone-assisted hue–saturation–value (HSV)/hexadecimal (HEX) analysis enabled quantitative on-site evaluation. Excellent selectivity and recoveries of 94.8%–109% (RSD ≤ 5.2%) were obtained in juices, sauces, powders, and candies, demonstrating strong practical utility. The film offers a stable, low-cost platform for field-level monitoring of azo dye adulteration.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 4","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a 3D-Printed Electrochemical Platform With Dual Working Electrodes for Mesalamine Detection 三维打印双工作电极检测美沙拉胺电化学平台的研制

IF 3.3

Analysis & sensing Pub Date : 2026-06-14 DOI: 10.1002/anse.70096

Mariana A. de Jesus, Larissa A. Silva, Beatriz F. Germinare, João Pedro C. Silva, Arielly Cardoso, Diego P. Rocha, Rafael M. Dornellas, Jéssica R. Camargo, Bruno C. Janegitz

{"title":"Development of a 3D-Printed Electrochemical Platform With Dual Working Electrodes for Mesalamine Detection","authors":"Mariana A. de Jesus, Larissa A. Silva, Beatriz F. Germinare, João Pedro C. Silva, Arielly Cardoso, Diego P. Rocha, Rafael M. Dornellas, Jéssica R. Camargo, Bruno C. Janegitz","doi":"10.1002/anse.70096","DOIUrl":"https://doi.org/10.1002/anse.70096","url":null,"abstract":"Additive manufacturing offers a versatile and cost-effective route for developing electrochemical sensors with customizable designs. In this work, we report an entirely 3D-printed multiplexed electrochemical device, fabricated via fused deposition modeling using carbon black/polylactic acid filament for the electrodes manufacturing, designed for the determination of mesalamine (MES). The proposed electrochemical platform integrates two working electrodes (E1 and E2), enabling multiplexed detection. After mechanical polishing and chemical/electrochemical activation in 0.5 mol L−1 NaOH, the electrodes displayed improved surface homogeneity and exposure of conductive domains, as confirmed by scanning electron microscopy, energy dispersive X-ray spectroscopy, contact angle, and attenuated total reflectance fourier-transform infrared spectroscopy analyses. The electrochemical behavior was evaluated by cyclic voltammetry, and MES quantification was performed using differential pulse voltammetry. The device exhibited linear response in the 1.0–100 µmol L−1 range, with limits of detection of 0.42 µmol L−1 (E1) and 0.37 µmol L−1 (E2). Recovery studies yielded satisfactory values, ranging from 89 to 113% in synthetic urine and 72 to 116% in human serum, confirming its suitability for complex biological matrices. The combination of low detection limits, reproducibility, and high recovery demonstrates the potential of this low-cost multiplexed 3D-printed platform for pharmaceutical monitoring and clinical applications.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 4","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.70096","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148282045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metabolic Fingerprints of High-Risk Individuals for Pancreatic Cancer: A Multibiospecimen Investigation 胰腺癌高危人群的代谢指纹图谱：一项多生物标本调查

IF 2.9

Analysis & sensing Pub Date : 2026-06-09 DOI: 10.1002/anse.70097

Vladyslav Dovhalyuk, Quang-Dong Bui, Vincent Ripoll, Wiktor Rutkowski, Miroslav Vujasinovic, J.-Matthias Löhr, Daniel Globisch

{"title":"Metabolic Fingerprints of High-Risk Individuals for Pancreatic Cancer: A Multibiospecimen Investigation","authors":"Vladyslav Dovhalyuk, Quang-Dong Bui, Vincent Ripoll, Wiktor Rutkowski, Miroslav Vujasinovic, J.-Matthias Löhr, Daniel Globisch","doi":"10.1002/anse.70097","DOIUrl":"https://doi.org/10.1002/anse.70097","url":null,"abstract":"Metabolomics analyses of human samples have a high potential to identify new metabolic markers that are important for disease development and can be utilized for disease diagnostics. To identify these disease-specific metabolic variations that represent medically important signatures, these metabolites have to be distinguished from common metabolic changes at a baseline level. Herein, we report a comprehensive metabolomics analysis of human fecal, plasma, and urine samples of high-risk patients for the development of pancreatic cancer to explore early metabolic alterations associated with the presence of pancreatic cysts. This study provides detailed metabolic insights across multiple biospecimens using a combination of multimatrix sampling and cofactor-adjusted statistical analysis. Importantly, we have identified several potential candidate markers, including methylglutaric acid (area under the curve (AUC) = 0.88), hydroxyindoleacetic acid (AUC = 0.82), and hypoxanthine (AUC = 0.82) associated with the presence of pancreatic cysts in an exploratory receiver operating characteristics analysis. Furthermore, bile acids, alkaloids, and fatty acids were identified to be altered in the individuals with cyst formation. We also identified a series of metabolites relevant for age- and sex-dependent differences. While validation in larger, longitudinal cohorts remains necessary, our findings lay a strong foundation for future investigations into metabolic markers of pancreatic pathology.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.70097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148237702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highly Selective Fluorescence Sensing of Ba2+ With a Benzo-21-Crown-7-Based BODIPY Through Modulation of an Intramolecular Charge Transfer in Aqueous Solution 通过调节水溶液中分子内电荷转移，苯并-21-冠-7基BODIPY对Ba2+的高选择性荧光传感

IF 2.9

Analysis & sensing Pub Date : 2026-06-01 DOI: 10.1002/anse.70093

Thomas Schwarze, Mazen Al Akrami, Tobias Sprenger, Nora Kulak

{"title":"Highly Selective Fluorescence Sensing of Ba2+ With a Benzo-21-Crown-7-Based BODIPY Through Modulation of an Intramolecular Charge Transfer in Aqueous Solution","authors":"Thomas Schwarze, Mazen Al Akrami, Tobias Sprenger, Nora Kulak","doi":"10.1002/anse.70093","DOIUrl":"https://doi.org/10.1002/anse.70093","url":null,"abstract":"A BODIPY dye functionalized at the 3 position with a benzo-21-crown-7 was investigated as a Ba2+-responsive fluorescent probe in aqueous solution. The dye possesses an extended D–π–A framework with strong intramolecular charge–transfer character, resulting in a low intrinsic fluorescence quantum yield (Φf = 0.021). Its emission is stable across a broad pH range and shows negligible photobleaching over typical measurement periods. Upon addition of Ba2+, the probe exhibits a pronounced fluorescence enhancement (FE = 10.3 ± 0.5) together with a slight hypsochromic shift. The Ba2+ affinity is reflected by an apparent dissociation constant of (4.7 ± 0.2) mM, and the limit of detection was determined to be (293 ± 12) µM. Extensive ion-interference studies reveal exceptional selectivity toward Ba2+, with only minimal response to Pb2+ among a wide variety of tested cations. These results establish the dye as a highly Ba2+-selective fluorescent probe suitable for sensing applications in aqueous environments.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.70093","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148173814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0