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Optical Sensor Arrays for the Detection of Neurotransmitters 用于检测神经递质的光学传感器阵列
IF 3.4
Analysis & sensing Pub Date : 2024-02-13 DOI: 10.1002/anse.202300099
Palash Jana, Prof. Subhajit Bandyopadhyay
{"title":"Optical Sensor Arrays for the Detection of Neurotransmitters","authors":"Palash Jana,&nbsp;Prof. Subhajit Bandyopadhyay","doi":"10.1002/anse.202300099","DOIUrl":"10.1002/anse.202300099","url":null,"abstract":"<p>Neurotransmitters are essential for electrochemical communication between neurons. Accurate detection and monitoring of neurotransmitters are crucial for comprehending the intricacies of the human nervous system. Despite their crucial role, neurotransmitters exist in the human body at low concentrations amidst other cellular components, posing challenges for their precise detection and quantification. While electrochemical detection stands as an important technique, its point-of-care diagnostic applications are constrained by complex machinery and sample preparation. To address this limitation, alternative detection strategies for neurotransmitters have been explored. This review discusses the development and principles of array-based sensors designed for facile and rapid detection of neurotransmitters. Moreover, it explores future prospects for the implementation and advancement of these techniques, envisioning a promising trajectory for improved understanding and manipulation of the human nervous system.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139780318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical Cross-Reactive Sensor Arrays** 光学交叉反应传感器阵列**
Analysis & sensing Pub Date : 2024-02-13 DOI: 10.1002/anse.202400004
Prof. Pavel Anzenbacher Jr., Prof. Elizabeth J. New
{"title":"Optical Cross-Reactive Sensor Arrays**","authors":"Prof. Pavel Anzenbacher Jr.,&nbsp;Prof. Elizabeth J. New","doi":"10.1002/anse.202400004","DOIUrl":"https://doi.org/10.1002/anse.202400004","url":null,"abstract":"<p>A prevailing scientific challenge is the accurate and sensitive detection of chemical species within complex systems. Sensor arrays are a valuable solution for many analyte classes. Guest Editors Pavel Anzenbacher, Jr. (Bowling Green State University, USA) and Elizabeth J. New (The University of Sydney, Australia) discuss the field and present the Special Collection on Optical Cross-Reactive Sensor Arrays.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visualizing Amyloid Assembly at the Nanoscale: Insights from Super-Resolution Imaging 纳米级淀粉样蛋白组装的可视化：超分辨率成像的启示
IF 3.4
Analysis & sensing Pub Date : 2024-02-10 DOI: 10.1002/anse.202400001
Kaustubh R. Bhuskute, Kai Kikuchi, Dr. Zijie Luo, Dr. Amandeep Kaur
{"title":"Visualizing Amyloid Assembly at the Nanoscale: Insights from Super-Resolution Imaging","authors":"Kaustubh R. Bhuskute,&nbsp;Kai Kikuchi,&nbsp;Dr. Zijie Luo,&nbsp;Dr. Amandeep Kaur","doi":"10.1002/anse.202400001","DOIUrl":"10.1002/anse.202400001","url":null,"abstract":"<p>In the rapidly evolving landscape of molecular imaging, super-resolution techniques emerge as indispensable tools, revolutionizing our capacity to decipher the intricacies of protein aggregation, and paving the way for molecular-level understanding of the progression of neurodegenerative disorders. In this review article we provide an overview of the diverse super-resolution imaging techniques applied to study amyloids at high resolution. We outline the strengths and limitations of each technique, offering insights into their applicability to different amyloid systems. We next delve into the diverse strategies employed for labeling amyloids in conjunction with super-resolution imaging. From small organic dyes to fluorescent proteins and advanced chemical probes, the discussion encompasses the strengths and considerations associated with each labeling method. The comparative analysis not only evaluates the impact of labeling on resolution and specificity but also highlights emerging trends and future directions in the field.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202400001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139787210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SERS Materials with Small-Molecule Sensitivity for Biological Diagnosis 用于生物诊断的具有小分子灵敏度的 SERS 材料
IF 3.4
Analysis & sensing Pub Date : 2024-01-30 DOI: 10.1002/anse.202300067
Yifan Xu, Qiuchen Dong, Shan Cong, Zhigang Zhao
{"title":"SERS Materials with Small-Molecule Sensitivity for Biological Diagnosis","authors":"Yifan Xu,&nbsp;Qiuchen Dong,&nbsp;Shan Cong,&nbsp;Zhigang Zhao","doi":"10.1002/anse.202300067","DOIUrl":"10.1002/anse.202300067","url":null,"abstract":"<p>Small molecule metabolites depict a biological system‘s status and help monitor disease conditions. Surface-enhanced Raman scattering (SERS) holds considerable promise as an instant and non-destructive detection tool for biological diagnosis. With single-molecular sensitivity, molecular fingerprint and water compatible, SERS provides valuable information about chemical structures and analyte compositions, especially desirable in biological diagnosis. Design and fabrication of effective, stable SERS substrates can be one of the major research priorities to provide small-molecule tracing with high sensitivity, selectivity, and reproducibility. Significant efforts have been directed towards creating high-performance and multifunctional SERS substrates spanning from coinage metals to semiconductor materials. However, most SERS substrates are suffering from unsatisfied sensitivity for tracing small molecules such as volatile organic compounds (VOCs) and other biomarkers. This review summarized recent advances in SERS-active substrates and their sensing for small biomarker molecules, especially VOCs in diagnosis.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300067","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140482972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Front Cover: Construction of an Oxidative Cleavage-Activated DNAzyme Biosensor for Rapid Detection and Cellular Imaging of the Myeloperoxidase Activity (Anal. Sens. 3/2024) 封面：构建氧化裂解激活 DNA 酶生物传感器，用于快速检测和细胞成像髓过氧化物酶活性（Anal.）
Analysis & sensing Pub Date : 2024-01-08 DOI: 10.1002/anse.202300094
Dr. Ming-Hao Liu, Ning-Ning Zhao, Wan-Tong Yu, Jin-Zhi Zhang, Prof. Zi-Yue Wang, Prof. Chun-Yang Zhang
{"title":"Front Cover: Construction of an Oxidative Cleavage-Activated DNAzyme Biosensor for Rapid Detection and Cellular Imaging of the Myeloperoxidase Activity (Anal. Sens. 3/2024)","authors":"Dr. Ming-Hao Liu,&nbsp;Ning-Ning Zhao,&nbsp;Wan-Tong Yu,&nbsp;Jin-Zhi Zhang,&nbsp;Prof. Zi-Yue Wang,&nbsp;Prof. Chun-Yang Zhang","doi":"10.1002/anse.202300094","DOIUrl":"https://doi.org/10.1002/anse.202300094","url":null,"abstract":"<p><b>The front cover picture shows</b> the formation of oxidative cleavage-activated DNAzyme that enables imaging of myeloperoxidase in living cells. More information can be found in the Research Article by Zi-Yue Wang, Chun-Yang Zhang, and co-workers.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Construction of an Oxidative Cleavage-Activated DNAzyme Biosensor for Rapid Detection and Cellular Imaging of the Myeloperoxidase Activity 构建氧化裂解激活 DNA 酶生物传感器，用于快速检测和细胞成像髓过氧化物酶活性
Analysis & sensing Pub Date : 2024-01-08 DOI: 10.1002/anse.202300095
Dr. Ming-Hao Liu, Ning-Ning Zhao, Wan-Tong Yu, Jin-Zhi Zhang, Prof. Zi-Yue Wang, Prof. Chun-Yang Zhang
{"title":"Construction of an Oxidative Cleavage-Activated DNAzyme Biosensor for Rapid Detection and Cellular Imaging of the Myeloperoxidase Activity","authors":"Dr. Ming-Hao Liu,&nbsp;Ning-Ning Zhao,&nbsp;Wan-Tong Yu,&nbsp;Jin-Zhi Zhang,&nbsp;Prof. Zi-Yue Wang,&nbsp;Prof. Chun-Yang Zhang","doi":"10.1002/anse.202300095","DOIUrl":"https://doi.org/10.1002/anse.202300095","url":null,"abstract":"<p>Invited for this month's cover is the collaborating group of Prof. Chun-Yang Zhang at Southeast University, China and colleagues at Shandong Normal University. The cover picture shows the formation of oxidative cleavage-activated DNAzyme that enables imaging of myeloperoxidase in living cells. More information can be found in the Research Article by Zi-Yue Wang, Chun-Yang Zhang, and co-workers.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Front Cover: The Lucigenin Assay: Measuring Anion Transport in Lipid Vesicles (Anal. Sens. 2/2024) 封面：褐藻素测定法：测量脂质囊泡中的阴离子转运（Anal. Sens. 2/2024）
Analysis & sensing Pub Date : 2024-01-04 DOI: 10.1002/anse.202300092
Matúš Chvojka, Anurag Singh, Alessio Cataldo, Dr. Aaron Torres-Huerta, Dr. Marcin Konopka, Prof. Vladimír Šindelář, Dr. Hennie Valkenier
{"title":"Front Cover: The Lucigenin Assay: Measuring Anion Transport in Lipid Vesicles (Anal. Sens. 2/2024)","authors":"Matúš Chvojka,&nbsp;Anurag Singh,&nbsp;Alessio Cataldo,&nbsp;Dr. Aaron Torres-Huerta,&nbsp;Dr. Marcin Konopka,&nbsp;Prof. Vladimír Šindelář,&nbsp;Dr. Hennie Valkenier","doi":"10.1002/anse.202300092","DOIUrl":"https://doi.org/10.1002/anse.202300092","url":null,"abstract":"<p><b>The Front Cover picture shows</b> liposomes with a fluorescent probe encapsulated to study the transmembrane transport of anions across the liposomal membranes by synthetic anion transporters. The positively charged probe lucigenin or the zwitterionic probe bis(3-sulfopropyl)-9,9’-biacridine (SPBA) can be used for this purpose. This work details how the quenching of these probes can be monitored by fluorescence spectroscopy to study the transport of chloride and other anions. Cover design by Dr. Aaron Torres-Huerta. More information can be found in the Concept article by Hennie Valkenier and co-workers.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300092","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140135352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Opportunity and Challenge of Emerging COFs in Chemiresistive Sensing for Gas and Humidity 新兴 COF 在化学电阻式气体和湿度传感领域的机遇与挑战
Analysis & sensing Pub Date : 2024-01-02 DOI: 10.1002/anse.202300078
Aohan Mei, Zifan Yang, Min Zhou, Wei Jin, Yueli Liu, Wen Chen
{"title":"Opportunity and Challenge of Emerging COFs in Chemiresistive Sensing for Gas and Humidity","authors":"Aohan Mei,&nbsp;Zifan Yang,&nbsp;Min Zhou,&nbsp;Wei Jin,&nbsp;Yueli Liu,&nbsp;Wen Chen","doi":"10.1002/anse.202300078","DOIUrl":"10.1002/anse.202300078","url":null,"abstract":"<p>Novel 2D materials for chemiresistive sensors are attractive due to their large surface area and structure diversity. Covalent organic frameworks (COFs) have received much attention due to their unique properties, including the abundant choice of organic building units, permanent pore structure and crystallinity, which show huge potential of implement in gas and humidity detection in complex environment. Recently, the development of the synthesis and modification methods for COFs powder and film contributes to the sensitivity and compatibility in chemiresistive sensors and integrated devices. In the present review, the current synthesis methods of COFs powder and film as well as their application in the chemiresistive sensors are summarized. The current challenge and future modification strategy are discussed for the further development of COFs as active materials in gas and humidity sensors.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139452284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rational Integration of Nanozyme Probe and Smartphone Device for On-Site Analysis 合理整合纳米酶探针和智能手机设备，实现现场分析
Analysis & sensing Pub Date : 2023-12-27 DOI: 10.1002/anse.202300084
Tong Wu, Prof. Quan Zhou, Prof. Guosheng Chen, Prof. Siming Huang, Prof. Gangfeng Ouyang
{"title":"Rational Integration of Nanozyme Probe and Smartphone Device for On-Site Analysis","authors":"Tong Wu,&nbsp;Prof. Quan Zhou,&nbsp;Prof. Guosheng Chen,&nbsp;Prof. Siming Huang,&nbsp;Prof. Gangfeng Ouyang","doi":"10.1002/anse.202300084","DOIUrl":"10.1002/anse.202300084","url":null,"abstract":"<p>On-site detection featuring miniaturized, integrated analytical device and rapid data feedback has encouraged a great deal of attention, especially in the current context of pandemic diseases occurring with high frequency worldwide. This convenient detection device constitutes a stable recognition element and a portable signal treatment and readout module. In this regard, the enzyme-mimic nanomaterials (nanozymes) with the merits of structural stability, cost efficiency, scale-up synthesis and high recyclability well meet the requirements for recognition unit set-up. While the all-pervading smartphone, which enables the data collection through photography or wireless transmission, holds numerous opportunities in the design of hand-held analytical device. In this review, we summarize the advances of nanozyme-smartphone integrated platforms, with special emphasis of the signal transduction principles involving colorimetric, chemiluminescence, and electrochemical signals. The diversified on-site applications in terms of biological, environment and food analysis are showcased. Finally, the current challenges as well as the future perspectives on nanozyme design, sensing diversity and smartphone analysis are discussed.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140502719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rapid Identification of Phenolics in Mixtures by Two-Dimensional Tandem Mass Spectrometry with Microdroplet Accelerated Derivatization Reactions 利用微液滴加速衍生化反应的二维串联质谱法快速鉴定混合物中的酚类物质
Analysis & sensing Pub Date : 2023-12-15 DOI: 10.1002/anse.202300081
Yanyang Hu, Dr. Eric T. Dziekonski, Donna M. Wang, Dr. L. Edwin Gonzalez, Prof. R. Graham Cooks
{"title":"Rapid Identification of Phenolics in Mixtures by Two-Dimensional Tandem Mass Spectrometry with Microdroplet Accelerated Derivatization Reactions","authors":"Yanyang Hu,&nbsp;Dr. Eric T. Dziekonski,&nbsp;Donna M. Wang,&nbsp;Dr. L. Edwin Gonzalez,&nbsp;Prof. R. Graham Cooks","doi":"10.1002/anse.202300081","DOIUrl":"10.1002/anse.202300081","url":null,"abstract":"<p>Complex mixtures are typically analyzed by chromatographic separation followed by mass spectrometry. Two-dimensional tandem mass spectrometry (2D MS/MS) may eliminate the need for separation and therefore significantly reduce analysis time while expanding the information space by recording the intensities of all fragment ions generated from all trapped precursor ions. Additional chemical specificity can be provided by using chemical derivatization. In this study phenolic compounds are identified after triazole click derivatization by the observation of two diagnostic features in the 2D MS/MS data domain, a mass shift of 175 Da on the precursor ion axis and a neutral loss (NL) of 119 Da. Additional NL transitions were highly correlated with particular substituents including carbonyl, ester, amino, and alkyl/phenyl groups. Substituent position information was also easily diagnosed. The derivatization reactions are accelerated in the charged electrosprayed microdroplets. Using this method, members of this single class of compounds can be identified within 1–2 minutes while structural information on the individual compounds is acquired simultaneously.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138997608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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