Analysis & sensing最新文献

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Detection of Perchlorate in Swabs Using Linear Sweep Voltammetry at a Liquid–Liquid Microinterface Array 液-液微界面阵列线性扫描伏安法检测棉签中的高氯酸盐
IF 2.9
Analysis & sensing Pub Date : 2026-04-10 DOI: 10.1002/anse.202500149
Celine P. A. Otiob, Hum B. Lamichhane, Xiaoqing Lv, Lauren N. Gilson, Philip W. Bateman, Damien W. M. Arrigan
{"title":"Detection of Perchlorate in Swabs Using Linear Sweep Voltammetry at a Liquid–Liquid Microinterface Array","authors":"Celine P. A. Otiob,&nbsp;Hum B. Lamichhane,&nbsp;Xiaoqing Lv,&nbsp;Lauren N. Gilson,&nbsp;Philip W. Bateman,&nbsp;Damien W. M. Arrigan","doi":"10.1002/anse.202500149","DOIUrl":"https://doi.org/10.1002/anse.202500149","url":null,"abstract":"<p>Perchlorate is a potential environmental contaminant and ease of its detection is needed to support environmental monitoring. Current detection methods mainly involve chromatographic and mass spectrometric methods, which have limitations in terms of portability and cost. This study explores the use of electrochemistry at the interface between two immiscible electrolyte solutions (ITIES) as an approach for perchlorate detection within sample swabs, e.g., from plant leaf surfaces in areas which may be contaminated with debris from frequent firework displays. Ion transfer voltammetry was employed to detect perchlorate based on its transfer across an array of micrometer-scale ITIES (µITIES). Experiments to evaluate sensitivity and selectivity of the approach enabled detection of less than 1 μM of perchlorate; the presence of common additional ions, such as nitrate, hydrogen phosphate, and sulfate, did not impact the detection of perchlorate. A series of experiments in which perchlorate was intentionally introduced into samples, both on cotton swabs and on leaf surfaces that were subsequently swabbed, showed that cotton swabs could be used to sample perchlorate from environmental surfaces. Field sampling of leaf surface before and after firework displays indicates that ion transfer voltammetry at a µITIES array offers a viable approach to the detection of perchlorate in swabs and on swabbed surfaces.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202500149","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147686013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probing the Missing Links: Mass Spectrometry of Small-Molecule Clusters on the Pathway to Fibrils and Crystals 探测缺失环节:通往原纤维和晶体的小分子簇的质谱分析
IF 2.9
Analysis & sensing Pub Date : 2026-03-22 DOI: 10.1002/anse.202500241
Thanh D. Do
{"title":"Probing the Missing Links: Mass Spectrometry of Small-Molecule Clusters on the Pathway to Fibrils and Crystals","authors":"Thanh D. Do","doi":"10.1002/anse.202500241","DOIUrl":"https://doi.org/10.1002/anse.202500241","url":null,"abstract":"<p>Small molecules such as amino acids (AAs) and metabolites are often treated as chemically simple species that either remain soluble or crystallize directly into ordered solids. Growing evidence challenges this view, revealing that many metabolites populate rich assembly landscapes containing oligomers and amyloid-like fibrils that bridge the gap between monomers and crystals. Far from being transient curiosities, these intermediate states can encode structural information that shapes toxicity, polymorph selection, catalysis, and disease progression. In this review, we explore how analytical mass spectrometry (MS), particularly ion mobility spectrometry–MS (IMS–MS) and MS-coupled ion spectroscopy, has opened a window onto these otherwise hidden assemblies. We show how IMS–MS resolves heterogeneous populations, captures early nucleation events, and exposes the decisive roles of charge balance, counterions, and additives in steering assembly pathways. Through representative examples spanning AAs and metabolites linked to amyloid formation and pathological crystallization, we argue that fibrillar intermediates can serve as deterministic waypoints rather than kinetic dead ends. We also confront the current limits of structural MS, from charge-induced bias to spectral congestion and modeling challenges, and highlight emerging solutions enabled by gentler ion handling, cryogenic spectroscopy, multidimensional IMS, and data-driven computation. Together, these advances transform MS from a passive observer into an active guide for discovering and predicting order in small-molecule assemblies.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147568194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probing the Missing Links: Mass Spectrometry of Small-Molecule Clusters on the Pathway to Fibrils and Crystals 探测缺失环节:通往原纤维和晶体的小分子簇的质谱分析
IF 2.9
Analysis & sensing Pub Date : 2026-03-22 DOI: 10.1002/anse.202500241
Thanh D. Do
{"title":"Probing the Missing Links: Mass Spectrometry of Small-Molecule Clusters on the Pathway to Fibrils and Crystals","authors":"Thanh D. Do","doi":"10.1002/anse.202500241","DOIUrl":"https://doi.org/10.1002/anse.202500241","url":null,"abstract":"<p>Small molecules such as amino acids (AAs) and metabolites are often treated as chemically simple species that either remain soluble or crystallize directly into ordered solids. Growing evidence challenges this view, revealing that many metabolites populate rich assembly landscapes containing oligomers and amyloid-like fibrils that bridge the gap between monomers and crystals. Far from being transient curiosities, these intermediate states can encode structural information that shapes toxicity, polymorph selection, catalysis, and disease progression. In this review, we explore how analytical mass spectrometry (MS), particularly ion mobility spectrometry–MS (IMS–MS) and MS-coupled ion spectroscopy, has opened a window onto these otherwise hidden assemblies. We show how IMS–MS resolves heterogeneous populations, captures early nucleation events, and exposes the decisive roles of charge balance, counterions, and additives in steering assembly pathways. Through representative examples spanning AAs and metabolites linked to amyloid formation and pathological crystallization, we argue that fibrillar intermediates can serve as deterministic waypoints rather than kinetic dead ends. We also confront the current limits of structural MS, from charge-induced bias to spectral congestion and modeling challenges, and highlight emerging solutions enabled by gentler ion handling, cryogenic spectroscopy, multidimensional IMS, and data-driven computation. Together, these advances transform MS from a passive observer into an active guide for discovering and predicting order in small-molecule assemblies.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147567920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Self-Powered Potentiometric Sensing of Amoxicillin in Cow Milk and Waste Water Over Zinc Oxide Encapsulated Cellulose-Grafted Polyaniline 氧化锌包封纤维素接枝聚苯胺对牛奶和废水中阿莫西林的自供电电位传感
IF 2.9
Analysis & sensing Pub Date : 2026-03-16 DOI: 10.1002/anse.202500232
Chandra Shekhar Kushwaha, Vinay Kumar Singh, Nand Gopal Giri, Saroj Kr. Shukla
{"title":"Self-Powered Potentiometric Sensing of Amoxicillin in Cow Milk and Waste Water Over Zinc Oxide Encapsulated Cellulose-Grafted Polyaniline","authors":"Chandra Shekhar Kushwaha,&nbsp;Vinay Kumar Singh,&nbsp;Nand Gopal Giri,&nbsp;Saroj Kr. Shukla","doi":"10.1002/anse.202500232","DOIUrl":"https://doi.org/10.1002/anse.202500232","url":null,"abstract":"<p>A self-powered potentiometric sensing of residual amoxicillin (AMX) in milk, meat extract and waste water of hospital has been demonstrated over zinc oxide, cellulose and polyaniline (ZnO-en-Cell-g-PANI) nanocomposite. The chemical structure, morphology, and properties of nanocomposite was investigated by suitable analytical techniques and ASTM methods. The observed analytical results confirms the porous and heterogeneous structure of composite with axial oriented crystallinity, ∼3.28 × 10<sup>–4</sup> S cm<sup>–1</sup> electrical conductivity, and chemical responsive nature. Further, the 100 μm film of ZnO-en-Cell-g-PANI nanocomposite coated on ITO glass plate to use as an electrode for potentiometric sensing of residual AMX in waste water, meat extract and milk samples under optimum conditions and using own fabricated sensing set up. The experimental result revealed reproducibility, linear sensing range from 0.5 to 100.0 µM AMX concentrations, 2.24 mV µM<sup>−1</sup> cm<sup>−2</sup> sensitivity, 3.45 × 10<sup>−2 </sup>µM detection limit, 180 s response time, 20 s recovery time, 45 days stability at 7.0 pH and room temperature. The mechanism for non-enzymatic sensing of AMX has been proposed after correlating the induced potential and electrochemical surface interaction occurring between AMX molecules and ZnO-en-Cell-g-PANI.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147637144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Self-Powered Potentiometric Sensing of Amoxicillin in Cow Milk and Waste Water Over Zinc Oxide Encapsulated Cellulose-Grafted Polyaniline 氧化锌包封纤维素接枝聚苯胺对牛奶和废水中阿莫西林的自供电电位传感
IF 2.9
Analysis & sensing Pub Date : 2026-03-16 DOI: 10.1002/anse.202500232
Chandra Shekhar Kushwaha, Vinay Kumar Singh, Nand Gopal Giri, Saroj Kr. Shukla
{"title":"Self-Powered Potentiometric Sensing of Amoxicillin in Cow Milk and Waste Water Over Zinc Oxide Encapsulated Cellulose-Grafted Polyaniline","authors":"Chandra Shekhar Kushwaha,&nbsp;Vinay Kumar Singh,&nbsp;Nand Gopal Giri,&nbsp;Saroj Kr. Shukla","doi":"10.1002/anse.202500232","DOIUrl":"https://doi.org/10.1002/anse.202500232","url":null,"abstract":"<p>A self-powered potentiometric sensing of residual amoxicillin (AMX) in milk, meat extract and waste water of hospital has been demonstrated over zinc oxide, cellulose and polyaniline (ZnO-en-Cell-g-PANI) nanocomposite. The chemical structure, morphology, and properties of nanocomposite was investigated by suitable analytical techniques and ASTM methods. The observed analytical results confirms the porous and heterogeneous structure of composite with axial oriented crystallinity, ∼3.28 × 10<sup>–4</sup> S cm<sup>–1</sup> electrical conductivity, and chemical responsive nature. Further, the 100 μm film of ZnO-en-Cell-g-PANI nanocomposite coated on ITO glass plate to use as an electrode for potentiometric sensing of residual AMX in waste water, meat extract and milk samples under optimum conditions and using own fabricated sensing set up. The experimental result revealed reproducibility, linear sensing range from 0.5 to 100.0 µM AMX concentrations, 2.24 mV µM<sup>−1</sup> cm<sup>−2</sup> sensitivity, 3.45 × 10<sup>−2 </sup>µM detection limit, 180 s response time, 20 s recovery time, 45 days stability at 7.0 pH and room temperature. The mechanism for non-enzymatic sensing of AMX has been proposed after correlating the induced potential and electrochemical surface interaction occurring between AMX molecules and ZnO-en-Cell-g-PANI.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147637145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Albumin-Assisted Supramolecular Probe for Ratiometric Detection of PFAS in Aqueous Medium 白蛋白辅助超分子探针用于水介质中PFAS的比例检测
IF 2.9
Analysis & sensing Pub Date : 2026-03-16 DOI: 10.1002/anse.202500207
Supriya Joshi, Ritika Joshi, Abhay Vijay Kotkondawar, Manojkumar Jadhao
{"title":"Albumin-Assisted Supramolecular Probe for Ratiometric Detection of PFAS in Aqueous Medium","authors":"Supriya Joshi,&nbsp;Ritika Joshi,&nbsp;Abhay Vijay Kotkondawar,&nbsp;Manojkumar Jadhao","doi":"10.1002/anse.202500207","DOIUrl":"https://doi.org/10.1002/anse.202500207","url":null,"abstract":"<p>Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants, and their growing concern requires the development of efficient detection methodologies. The present article introduces a novel supramolecular host–guest sensing system using human serum albumin (HSA) as the host and a specifically designed chromophoric azo dye, (E)-(2-hydroxy-5-((3,4,5-trimethoxyphenyl)diazenyl)phenyl)(pyrrolidine-1-yl)methanone (TPAZ), as the guest. The probe was used for ratiometric and colorimetric detection of PFOS, PFOA, and PFNA. Absorbance and fluorescence techniques were used to study the photophysical properties, binding stoichiometry, and site-specific interactions. The density functional theory calculations also supporting strong intramolecular charge transfer behavior and visible-light absorption. The TPAZ–HSA complex showed distinct spectral shifts and a visible color change from yellow to colorless upon interaction with PFAS, enabling rapid and selective detection, however, the sensor is selective toward PFAS as a class but not toward individual PFAS. This probe enables simple paper-based test strips for on-site PFAS detection in water using smartphhgone images. Molecular docking revealed the sensing mechanism and competitive binding of TPAZ and PFAS at albumin sites. This article demonstrates a simple, cost-effective, and selective sensing approach for on-site detection of PFAS in aqueous systems.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147637035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Albumin-Assisted Supramolecular Probe for Ratiometric Detection of PFAS in Aqueous Medium 白蛋白辅助超分子探针用于水介质中PFAS的比例检测
IF 2.9
Analysis & sensing Pub Date : 2026-03-16 DOI: 10.1002/anse.202500207
Supriya Joshi, Ritika Joshi, Abhay Vijay Kotkondawar, Manojkumar Jadhao
{"title":"Albumin-Assisted Supramolecular Probe for Ratiometric Detection of PFAS in Aqueous Medium","authors":"Supriya Joshi,&nbsp;Ritika Joshi,&nbsp;Abhay Vijay Kotkondawar,&nbsp;Manojkumar Jadhao","doi":"10.1002/anse.202500207","DOIUrl":"https://doi.org/10.1002/anse.202500207","url":null,"abstract":"<p>Per- and polyfluoroalkyl substances (PFAS) are persistent environmental pollutants, and their growing concern requires the development of efficient detection methodologies. The present article introduces a novel supramolecular host–guest sensing system using human serum albumin (HSA) as the host and a specifically designed chromophoric azo dye, (E)-(2-hydroxy-5-((3,4,5-trimethoxyphenyl)diazenyl)phenyl)(pyrrolidine-1-yl)methanone (TPAZ), as the guest. The probe was used for ratiometric and colorimetric detection of PFOS, PFOA, and PFNA. Absorbance and fluorescence techniques were used to study the photophysical properties, binding stoichiometry, and site-specific interactions. The density functional theory calculations also supporting strong intramolecular charge transfer behavior and visible-light absorption. The TPAZ–HSA complex showed distinct spectral shifts and a visible color change from yellow to colorless upon interaction with PFAS, enabling rapid and selective detection, however, the sensor is selective toward PFAS as a class but not toward individual PFAS. This probe enables simple paper-based test strips for on-site PFAS detection in water using smartphhgone images. Molecular docking revealed the sensing mechanism and competitive binding of TPAZ and PFAS at albumin sites. This article demonstrates a simple, cost-effective, and selective sensing approach for on-site detection of PFAS in aqueous systems.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147637143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mixed-Oxide Nanostructure-Based Electrochemical Sensors for Environmental Pollutants 基于混合氧化物纳米结构的环境污染物电化学传感器
IF 2.9
Analysis & sensing Pub Date : 2026-03-16 DOI: 10.1002/anse.202500221
Cavour M. Neto, Camila C. Silva, Carlos W. Mendonça, Daniel Y. Tiba, João H. A. Ferreira, Laura C. Lieb, Octávio P. L. de Souza, Willian V. L. Belino, J. G. Manjunatha, Thiago C. Canevari
{"title":"Mixed-Oxide Nanostructure-Based Electrochemical Sensors for Environmental Pollutants","authors":"Cavour M. Neto,&nbsp;Camila C. Silva,&nbsp;Carlos W. Mendonça,&nbsp;Daniel Y. Tiba,&nbsp;João H. A. Ferreira,&nbsp;Laura C. Lieb,&nbsp;Octávio P. L. de Souza,&nbsp;Willian V. L. Belino,&nbsp;J. G. Manjunatha,&nbsp;Thiago C. Canevari","doi":"10.1002/anse.202500221","DOIUrl":"https://doi.org/10.1002/anse.202500221","url":null,"abstract":"<p>Emerging environmental pollutants pose increasing risks to ecosystems and human health, creating a demand for analytical tools capable of sensitive and selective detection in complex environmental matrices. In this context, electrochemical sensors based on mixed-oxide nanostructured materials have attracted growing interest due to their excellent electrocatalytic activity, tunable surface properties, acid-basic Lewis and Bronsted properties, and suitability for on-site monitoring. This review examines recent advances in mixed-oxide-based electrochemical sensors for the detection of environmental pollutants, including pharmaceuticals, dyes, Anti-inflammatory and antipyretic drugs, pesticides, endocrine-disrupting compounds, and heavy metals. The review also explores how material composition, synergistic interactions between metal centers, and nanostructure design affect the electroanalytical performance of modified electrodes. Current challenges related to reproducibility, stability, and selectivity are also discussed, along with perspectives for the rational design and practical application of these sensors in environmental monitoring.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202500221","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147637142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mixed-Oxide Nanostructure-Based Electrochemical Sensors for Environmental Pollutants 基于混合氧化物纳米结构的环境污染物电化学传感器
IF 2.9
Analysis & sensing Pub Date : 2026-03-16 DOI: 10.1002/anse.202500221
Cavour M. Neto, Camila C. Silva, Carlos W. Mendonça, Daniel Y. Tiba, João H. A. Ferreira, Laura C. Lieb, Octávio P. L. de Souza, Willian V. L. Belino, J. G. Manjunatha, Thiago C. Canevari
{"title":"Mixed-Oxide Nanostructure-Based Electrochemical Sensors for Environmental Pollutants","authors":"Cavour M. Neto,&nbsp;Camila C. Silva,&nbsp;Carlos W. Mendonça,&nbsp;Daniel Y. Tiba,&nbsp;João H. A. Ferreira,&nbsp;Laura C. Lieb,&nbsp;Octávio P. L. de Souza,&nbsp;Willian V. L. Belino,&nbsp;J. G. Manjunatha,&nbsp;Thiago C. Canevari","doi":"10.1002/anse.202500221","DOIUrl":"https://doi.org/10.1002/anse.202500221","url":null,"abstract":"<p>Emerging environmental pollutants pose increasing risks to ecosystems and human health, creating a demand for analytical tools capable of sensitive and selective detection in complex environmental matrices. In this context, electrochemical sensors based on mixed-oxide nanostructured materials have attracted growing interest due to their excellent electrocatalytic activity, tunable surface properties, acid-basic Lewis and Bronsted properties, and suitability for on-site monitoring. This review examines recent advances in mixed-oxide-based electrochemical sensors for the detection of environmental pollutants, including pharmaceuticals, dyes, Anti-inflammatory and antipyretic drugs, pesticides, endocrine-disrupting compounds, and heavy metals. The review also explores how material composition, synergistic interactions between metal centers, and nanostructure design affect the electroanalytical performance of modified electrodes. Current challenges related to reproducibility, stability, and selectivity are also discussed, along with perspectives for the rational design and practical application of these sensors in environmental monitoring.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202500221","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147637146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization of Nanoparticles by Taylor Dispersion Analysis Hyphenated to Charge Detection Mass Spectrometry 纳米粒子的泰勒色散-电荷检测质谱分析表征
IF 2.9
Analysis & sensing Pub Date : 2026-03-09 DOI: 10.1002/anse.202500245
Tessa Reinert, Séléna Ferreres, Lilou Duplantier, Dipankar Bain, Guillaume Montagne, Sylvain Maclot, Martinus H. V. Werts, Rodolphe Antoine
{"title":"Characterization of Nanoparticles by Taylor Dispersion Analysis Hyphenated to Charge Detection Mass Spectrometry","authors":"Tessa Reinert,&nbsp;Séléna Ferreres,&nbsp;Lilou Duplantier,&nbsp;Dipankar Bain,&nbsp;Guillaume Montagne,&nbsp;Sylvain Maclot,&nbsp;Martinus H. V. Werts,&nbsp;Rodolphe Antoine","doi":"10.1002/anse.202500245","DOIUrl":"https://doi.org/10.1002/anse.202500245","url":null,"abstract":"<p>The article establishes a new framework for the multimodal characterization of nanoparticles in the ultrahigh mass range. In this new framework, Taylor dispersion analysis (TDA) is integrated with in-line optical absorbance spectroscopy and directly coupled to an electrospray ionization (ESI) interface. This configuration enables controlled transfer of analytes to charge detection mass spectrometry (CDMS), providing information about ion charge, mass, and optical properties. This innovative hyphenated setup is described using 60 nm gold nanoparticles, corresponding to a particle mass of ≈1.3 GDa, as a proof of concept. Taylorgrams obtained with analyte temporal diffusion monitoring by UV/vis spectroscopy and by CDMS are discussed in fame with numerical model and point out the associated challenges for size determination.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"6 2","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202500245","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147636971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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