发布求助
文献互助 智能选刊 最新文献

Analysis & sensing最新文献

筛选
英文 中文
Rapid Characterization of Phospholipids from Biological Matrix Enabled by Indium Tin Oxide (ITO) Coated Slide Assisted Enrichment MALDI Mass Spectrometry 利用氧化铟锡 (ITO) 涂层玻片辅助富集 MALDI 质谱法快速表征生物基质中的磷脂
Analysis & sensing Pub Date : 2024-02-28 DOI: 10.1002/anse.202300097
Penghsuan Huang, Dr. Hua Zhang, Yuan Liu, Prof. Lingjun Li
{"title":"Rapid Characterization of Phospholipids from Biological Matrix Enabled by Indium Tin Oxide (ITO) Coated Slide Assisted Enrichment MALDI Mass Spectrometry","authors":"Penghsuan Huang,&nbsp;Dr. Hua Zhang,&nbsp;Yuan Liu,&nbsp;Prof. Lingjun Li","doi":"10.1002/anse.202300097","DOIUrl":"10.1002/anse.202300097","url":null,"abstract":"<p>Lipidomic analysis of human serum is essential to monitor the individual's health status. Herein, we develop a facile strategy for rapid characterization of phospholipids in human serum via indium tin oxide (ITO) coated glass slide solid phase extraction MALDI mass spectrometry (ITO-SPE-MALDI-MS). Phospholipid species are retained on ITO slide via solid phase extraction owing to the unique property of the ITO material; the measurement of phospholipid species from 1 μl human serum within 2 min is achievable. A comparison of ITO-SPE strategy with conventional extraction methods was further carried out using liquid chromatography-mass spectrometry (LC-MS) and ion-mobility mass spectrometry (IM-MS), resulting in a comparable enrichment performance for the phospholipid analysis. Furthermore, rapid lipidomic profiling of serum samples from human colorectal cancer patients and cell lines was demonstrated. Our results indicate that ITO-SPE-MALDI-MS provides a higher throughput strategy for the analysis of phospholipid species in complex biological mixtures, showcasing its potential for applications in the analysis of clinical biofluids.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140422110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotic Resistance Detection in Pseudomonas aeruginosa: Recent Strategies, Advances, and Challenges 铜绿假单胞菌的抗生素耐药性检测：最新策略、进展与挑战
IF 3.4
Analysis & sensing Pub Date : 2024-02-20 DOI: 10.1002/anse.202300058
Luma Clarindo Lopes, Dr. Ashkan Koushanpour, Kolby Wiebe, Prof. Dr. Sabine Kuss
{"title":"Antibiotic Resistance Detection in Pseudomonas aeruginosa: Recent Strategies, Advances, and Challenges","authors":"Luma Clarindo Lopes,&nbsp;Dr. Ashkan Koushanpour,&nbsp;Kolby Wiebe,&nbsp;Prof. Dr. Sabine Kuss","doi":"10.1002/anse.202300058","DOIUrl":"10.1002/anse.202300058","url":null,"abstract":"<p>Antibiotic resistance presents a worldwide public health emergency, impeding the effective management of infectious diseases. <i>Pseudomonas aeruginosa</i> plays a substantial role as a bacterial pathogen, particularly in infections among hospitalized individuals, and those with weakened immune systems. Timely and accurate detection of antimicrobial resistance in <i>P. aeruginosa</i> is crucial for initiating tailored antibiotic therapy promptly, thus improving patient outcomes. Nevertheless, this endeavor encounters challenges due to the intricate and varied nature of antibiotic-resistant strains. Extensive efforts have been invested in developing sensors and instrumentations for assessing antibiotic resistance or susceptibility (AST), aiming to enable personalized patient treatment with appropriate medications. This paper focuses on recent advancements in these methodologies, utilized for evaluating the degree of antibiotic resistance or susceptibility in pathogenic bacteria. Flow cytometry, dual molecular recognition and mass spectrometry are presented as newer phenotypic AST techniques. Genomic methods and the pyocyanin detection are listed as methodologies for the detection of resistance indicators.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 4","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300058","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140448095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Multimodal Bio-Sensing and Imaging Platform (MSIP) for Real-Time Intraoperative Margin Detection in Cancer Surgery 用于癌症手术术中实时边缘检测的多模态生物传感和成像平台 (MSIP)
Analysis & sensing Pub Date : 2024-02-16 DOI: 10.1002/anse.202300066
Ghazal Hatami-Fard, Khushi Vyas, Daniel Leff, Ranan Dasgupta, Salzitsa Anastasova
{"title":"A Multimodal Bio-Sensing and Imaging Platform (MSIP) for Real-Time Intraoperative Margin Detection in Cancer Surgery","authors":"Ghazal Hatami-Fard,&nbsp;Khushi Vyas,&nbsp;Daniel Leff,&nbsp;Ranan Dasgupta,&nbsp;Salzitsa Anastasova","doi":"10.1002/anse.202300066","DOIUrl":"10.1002/anse.202300066","url":null,"abstract":"<p>In cancer surgery, the precise characterisation of tissue margins is of paramount importance to ensure effective resection. However, conventional methods have inherent limitations in terms of both speed and accuracy, often necessitating labour-intensive postsurgical tissue analyses. To overcome these challenges and enhance the precision of cancer surgery, we introduced an innovative Multimodal Sensing and Imaging Platform (MSIP) equipped with advanced pH sensing capabilities. The MSIP represents the synergistic fusion of a miniaturised, flexible wire-based electrochemical pH sensor with a sensitivity of 62.4 mV per pH for real-time functional imaging. Simultaneously, it incorporates a high-speed confocal endomicroscope utilizing a 2.6 mm fibre bundle to achieve subcellular resolution in morphological imaging. The pH sensor enables continuous monitoring of dynamic changes in the tumour microenvironment, offering valuable insights. Confocal endomicroscopy provides high-resolution, real-time imaging of tumour morphology with an impressive 2.2 μm resolution. This integration not only enhances the precision of cancer surgery but also fosters a comprehensive understanding of the biological and molecular characteristics of tumours. By consolidating multiple diagnostic parameters into a unified platform, MSIP has emerged as a transformative technology poised to revolutionise our approach to cancer surgery.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300066","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140454409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Lucigenin Assay: Measuring Anion Transport in Lipid Vesicles 褐藻素测定法：测量脂质囊泡中的阴离子转运
Analysis & sensing Pub Date : 2024-02-13 DOI: 10.1002/anse.202300093
Matúš Chvojka, Anurag Singh, Alessio Cataldo, Dr. Aaron Torres-Huerta, Dr. Marcin Konopka, Prof. Vladimír Šindelář, Dr. Hennie Valkenier
{"title":"The Lucigenin Assay: Measuring Anion Transport in Lipid Vesicles","authors":"Matúš Chvojka,&nbsp;Anurag Singh,&nbsp;Alessio Cataldo,&nbsp;Dr. Aaron Torres-Huerta,&nbsp;Dr. Marcin Konopka,&nbsp;Prof. Vladimír Šindelář,&nbsp;Dr. Hennie Valkenier","doi":"10.1002/anse.202300093","DOIUrl":"https://doi.org/10.1002/anse.202300093","url":null,"abstract":"<p>Invited for this month′s cover are the collaborating groups of the Université libre de Bruxelles and Masaryk University. The cover picture shows liposomes with a fluorescent probe encapsulated to study the transmembrane transport of chloride by synthetic anion transporters via quenching of the fluorescence. More information can be found in the Concept article by Hennie Valkenier and co-workers.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140135389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical Sensor Arrays for the Detection of Neurotransmitters 用于检测神经递质的光学传感器阵列
IF 3.4
Analysis & sensing Pub Date : 2024-02-13 DOI: 10.1002/anse.202300099
Palash Jana, Prof. Subhajit Bandyopadhyay
{"title":"Optical Sensor Arrays for the Detection of Neurotransmitters","authors":"Palash Jana,&nbsp;Prof. Subhajit Bandyopadhyay","doi":"10.1002/anse.202300099","DOIUrl":"10.1002/anse.202300099","url":null,"abstract":"<p>Neurotransmitters are essential for electrochemical communication between neurons. Accurate detection and monitoring of neurotransmitters are crucial for comprehending the intricacies of the human nervous system. Despite their crucial role, neurotransmitters exist in the human body at low concentrations amidst other cellular components, posing challenges for their precise detection and quantification. While electrochemical detection stands as an important technique, its point-of-care diagnostic applications are constrained by complex machinery and sample preparation. To address this limitation, alternative detection strategies for neurotransmitters have been explored. This review discusses the development and principles of array-based sensors designed for facile and rapid detection of neurotransmitters. Moreover, it explores future prospects for the implementation and advancement of these techniques, envisioning a promising trajectory for improved understanding and manipulation of the human nervous system.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 4","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139780318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optical Cross-Reactive Sensor Arrays** 光学交叉反应传感器阵列**
Analysis & sensing Pub Date : 2024-02-13 DOI: 10.1002/anse.202400004
Prof. Pavel Anzenbacher Jr., Prof. Elizabeth J. New
{"title":"Optical Cross-Reactive Sensor Arrays**","authors":"Prof. Pavel Anzenbacher Jr.,&nbsp;Prof. Elizabeth J. New","doi":"10.1002/anse.202400004","DOIUrl":"https://doi.org/10.1002/anse.202400004","url":null,"abstract":"<p>A prevailing scientific challenge is the accurate and sensitive detection of chemical species within complex systems. Sensor arrays are a valuable solution for many analyte classes. Guest Editors Pavel Anzenbacher, Jr. (Bowling Green State University, USA) and Elizabeth J. New (The University of Sydney, Australia) discuss the field and present the Special Collection on Optical Cross-Reactive Sensor Arrays.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visualizing Amyloid Assembly at the Nanoscale: Insights from Super-Resolution Imaging 纳米级淀粉样蛋白组装的可视化：超分辨率成像的启示
IF 3.4
Analysis & sensing Pub Date : 2024-02-10 DOI: 10.1002/anse.202400001
Kaustubh R. Bhuskute, Kai Kikuchi, Dr. Zijie Luo, Dr. Amandeep Kaur
{"title":"Visualizing Amyloid Assembly at the Nanoscale: Insights from Super-Resolution Imaging","authors":"Kaustubh R. Bhuskute,&nbsp;Kai Kikuchi,&nbsp;Dr. Zijie Luo,&nbsp;Dr. Amandeep Kaur","doi":"10.1002/anse.202400001","DOIUrl":"10.1002/anse.202400001","url":null,"abstract":"<p>In the rapidly evolving landscape of molecular imaging, super-resolution techniques emerge as indispensable tools, revolutionizing our capacity to decipher the intricacies of protein aggregation, and paving the way for molecular-level understanding of the progression of neurodegenerative disorders. In this review article we provide an overview of the diverse super-resolution imaging techniques applied to study amyloids at high resolution. We outline the strengths and limitations of each technique, offering insights into their applicability to different amyloid systems. We next delve into the diverse strategies employed for labeling amyloids in conjunction with super-resolution imaging. From small organic dyes to fluorescent proteins and advanced chemical probes, the discussion encompasses the strengths and considerations associated with each labeling method. The comparative analysis not only evaluates the impact of labeling on resolution and specificity but also highlights emerging trends and future directions in the field.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 4","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202400001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139787210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SERS Materials with Small-Molecule Sensitivity for Biological Diagnosis 用于生物诊断的具有小分子灵敏度的 SERS 材料
IF 3.4
Analysis & sensing Pub Date : 2024-01-30 DOI: 10.1002/anse.202300067
Yifan Xu, Qiuchen Dong, Shan Cong, Zhigang Zhao
{"title":"SERS Materials with Small-Molecule Sensitivity for Biological Diagnosis","authors":"Yifan Xu,&nbsp;Qiuchen Dong,&nbsp;Shan Cong,&nbsp;Zhigang Zhao","doi":"10.1002/anse.202300067","DOIUrl":"10.1002/anse.202300067","url":null,"abstract":"<p>Small molecule metabolites depict a biological system‘s status and help monitor disease conditions. Surface-enhanced Raman scattering (SERS) holds considerable promise as an instant and non-destructive detection tool for biological diagnosis. With single-molecular sensitivity, molecular fingerprint and water compatible, SERS provides valuable information about chemical structures and analyte compositions, especially desirable in biological diagnosis. Design and fabrication of effective, stable SERS substrates can be one of the major research priorities to provide small-molecule tracing with high sensitivity, selectivity, and reproducibility. Significant efforts have been directed towards creating high-performance and multifunctional SERS substrates spanning from coinage metals to semiconductor materials. However, most SERS substrates are suffering from unsatisfied sensitivity for tracing small molecules such as volatile organic compounds (VOCs) and other biomarkers. This review summarized recent advances in SERS-active substrates and their sensing for small biomarker molecules, especially VOCs in diagnosis.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 4","pages":""},"PeriodicalIF":3.4,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300067","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140482972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Front Cover: Construction of an Oxidative Cleavage-Activated DNAzyme Biosensor for Rapid Detection and Cellular Imaging of the Myeloperoxidase Activity (Anal. Sens. 3/2024) 封面：构建氧化裂解激活 DNA 酶生物传感器，用于快速检测和细胞成像髓过氧化物酶活性（Anal.）
Analysis & sensing Pub Date : 2024-01-08 DOI: 10.1002/anse.202300094
Dr. Ming-Hao Liu, Ning-Ning Zhao, Wan-Tong Yu, Jin-Zhi Zhang, Prof. Zi-Yue Wang, Prof. Chun-Yang Zhang
{"title":"Front Cover: Construction of an Oxidative Cleavage-Activated DNAzyme Biosensor for Rapid Detection and Cellular Imaging of the Myeloperoxidase Activity (Anal. Sens. 3/2024)","authors":"Dr. Ming-Hao Liu,&nbsp;Ning-Ning Zhao,&nbsp;Wan-Tong Yu,&nbsp;Jin-Zhi Zhang,&nbsp;Prof. Zi-Yue Wang,&nbsp;Prof. Chun-Yang Zhang","doi":"10.1002/anse.202300094","DOIUrl":"https://doi.org/10.1002/anse.202300094","url":null,"abstract":"<p><b>The front cover picture shows</b> the formation of oxidative cleavage-activated DNAzyme that enables imaging of myeloperoxidase in living cells. More information can be found in the Research Article by Zi-Yue Wang, Chun-Yang Zhang, and co-workers.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Construction of an Oxidative Cleavage-Activated DNAzyme Biosensor for Rapid Detection and Cellular Imaging of the Myeloperoxidase Activity 构建氧化裂解激活 DNA 酶生物传感器，用于快速检测和细胞成像髓过氧化物酶活性
Analysis & sensing Pub Date : 2024-01-08 DOI: 10.1002/anse.202300095
Dr. Ming-Hao Liu, Ning-Ning Zhao, Wan-Tong Yu, Jin-Zhi Zhang, Prof. Zi-Yue Wang, Prof. Chun-Yang Zhang
{"title":"Construction of an Oxidative Cleavage-Activated DNAzyme Biosensor for Rapid Detection and Cellular Imaging of the Myeloperoxidase Activity","authors":"Dr. Ming-Hao Liu,&nbsp;Ning-Ning Zhao,&nbsp;Wan-Tong Yu,&nbsp;Jin-Zhi Zhang,&nbsp;Prof. Zi-Yue Wang,&nbsp;Prof. Chun-Yang Zhang","doi":"10.1002/anse.202300095","DOIUrl":"https://doi.org/10.1002/anse.202300095","url":null,"abstract":"<p>Invited for this month's cover is the collaborating group of Prof. Chun-Yang Zhang at Southeast University, China and colleagues at Shandong Normal University. The cover picture shows the formation of oxidative cleavage-activated DNAzyme that enables imaging of myeloperoxidase in living cells. More information can be found in the Research Article by Zi-Yue Wang, Chun-Yang Zhang, and co-workers.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信