Analysis & sensing最新文献_第6页

Front Cover: The Lucigenin Assay: Measuring Anion Transport in Lipid Vesicles (Anal. Sens. 2/2024) 封面：褐藻素测定法：测量脂质囊泡中的阴离子转运（Anal. Sens. 2/2024）

Analysis & sensing Pub Date : 2024-01-04 DOI: 10.1002/anse.202300092

Matúš Chvojka, Anurag Singh, Alessio Cataldo, Dr. Aaron Torres-Huerta, Dr. Marcin Konopka, Prof. Vladimír Šindelář, Dr. Hennie Valkenier

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Opportunity and Challenge of Emerging COFs in Chemiresistive Sensing for Gas and Humidity 新兴 COF 在化学电阻式气体和湿度传感领域的机遇与挑战

Analysis & sensing Pub Date : 2024-01-02 DOI: 10.1002/anse.202300078

Aohan Mei, Zifan Yang, Min Zhou, Wei Jin, Yueli Liu, Wen Chen

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Rational Integration of Nanozyme Probe and Smartphone Device for On-Site Analysis 合理整合纳米酶探针和智能手机设备，实现现场分析

Analysis & sensing Pub Date : 2023-12-27 DOI: 10.1002/anse.202300084

Tong Wu, Prof. Quan Zhou, Prof. Guosheng Chen, Prof. Siming Huang, Prof. Gangfeng Ouyang

{"title":"Rational Integration of Nanozyme Probe and Smartphone Device for On-Site Analysis","authors":"Tong Wu, Prof. Quan Zhou, Prof. Guosheng Chen, Prof. Siming Huang, Prof. Gangfeng Ouyang","doi":"10.1002/anse.202300084","DOIUrl":"10.1002/anse.202300084","url":null,"abstract":"On-site detection featuring miniaturized, integrated analytical device and rapid data feedback has encouraged a great deal of attention, especially in the current context of pandemic diseases occurring with high frequency worldwide. This convenient detection device constitutes a stable recognition element and a portable signal treatment and readout module. In this regard, the enzyme-mimic nanomaterials (nanozymes) with the merits of structural stability, cost efficiency, scale-up synthesis and high recyclability well meet the requirements for recognition unit set-up. While the all-pervading smartphone, which enables the data collection through photography or wireless transmission, holds numerous opportunities in the design of hand-held analytical device. In this review, we summarize the advances of nanozyme-smartphone integrated platforms, with special emphasis of the signal transduction principles involving colorimetric, chemiluminescence, and electrochemical signals. The diversified on-site applications in terms of biological, environment and food analysis are showcased. Finally, the current challenges as well as the future perspectives on nanozyme design, sensing diversity and smartphone analysis are discussed.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140502719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Rapid Identification of Phenolics in Mixtures by Two-Dimensional Tandem Mass Spectrometry with Microdroplet Accelerated Derivatization Reactions 利用微液滴加速衍生化反应的二维串联质谱法快速鉴定混合物中的酚类物质

Analysis & sensing Pub Date : 2023-12-15 DOI: 10.1002/anse.202300081

Yanyang Hu, Dr. Eric T. Dziekonski, Donna M. Wang, Dr. L. Edwin Gonzalez, Prof. R. Graham Cooks

{"title":"Rapid Identification of Phenolics in Mixtures by Two-Dimensional Tandem Mass Spectrometry with Microdroplet Accelerated Derivatization Reactions","authors":"Yanyang Hu, Dr. Eric T. Dziekonski, Donna M. Wang, Dr. L. Edwin Gonzalez, Prof. R. Graham Cooks","doi":"10.1002/anse.202300081","DOIUrl":"10.1002/anse.202300081","url":null,"abstract":"Complex mixtures are typically analyzed by chromatographic separation followed by mass spectrometry. Two-dimensional tandem mass spectrometry (2D MS/MS) may eliminate the need for separation and therefore significantly reduce analysis time while expanding the information space by recording the intensities of all fragment ions generated from all trapped precursor ions. Additional chemical specificity can be provided by using chemical derivatization. In this study phenolic compounds are identified after triazole click derivatization by the observation of two diagnostic features in the 2D MS/MS data domain, a mass shift of 175 Da on the precursor ion axis and a neutral loss (NL) of 119 Da. Additional NL transitions were highly correlated with particular substituents including carbonyl, ester, amino, and alkyl/phenyl groups. Substituent position information was also easily diagnosed. The derivatization reactions are accelerated in the charged electrosprayed microdroplets. Using this method, members of this single class of compounds can be identified within 1–2 minutes while structural information on the individual compounds is acquired simultaneously.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138997608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Non-invasive and Sensitive Fluorescence Detection of Phenylpyruvic Acid via a Guanidinomethyl-modified Calixarene 通过胍基甲基修饰的钙烯烃对苯丙酮酸进行非侵入式灵敏荧光检测

Analysis & sensing Pub Date : 2023-12-15 DOI: 10.1002/anse.202300082

Huan-Yu Wang, Zong-Ying Hu, Han-Wen Tian, Dr. Xin-Yue Hu, Dr. Yu-Chen Pan, Dr. Dong-Sheng Guo

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BODIPY-based Fluorescent Indicators for Lipid Droplets 基于 BODIPY 的脂滴荧光指示剂

Analysis & sensing Pub Date : 2023-12-14 DOI: 10.1002/anse.202300075

Dr. Jianping Zhu, Nian Kee Tan, Kai Kikuchi, Dr. Amandeep Kaur, Prof. Elizabeth J. New

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Braiding Three-Dimensional Paper-Based Microfluidic Devices 编织三维纸基微流体设备

Analysis & sensing Pub Date : 2023-11-29 DOI: 10.1002/anse.202300065

Cuiyun Jia, Bin Li, Dr. Jie Pan, Dr. Fengjiao Zhu, Xue Bai, Dr. Xianming Liu, Prof. Bingcheng Lin, Prof. Yahong Chen, Prof. Yao Lu

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Au-Modified Carbon Electrodes Produced by Laser Scribing for Electrochemical Analysis of Probiotic Activity 利用激光划线技术制作的金改性碳电极用于益生菌活性的电化学分析

Analysis & sensing Pub Date : 2023-11-28 DOI: 10.1002/anse.202300056

Juliana L. M. Gongoni, George Chumanov, Thiago R. L. C. Paixão, Dr. Carlos D. Garcia

{"title":"Au-Modified Carbon Electrodes Produced by Laser Scribing for Electrochemical Analysis of Probiotic Activity","authors":"Juliana L. M. Gongoni, George Chumanov, Thiago R. L. C. Paixão, Dr. Carlos D. Garcia","doi":"10.1002/anse.202300056","DOIUrl":"10.1002/anse.202300056","url":null,"abstract":"A simple and fast (<15 min), two-step laser scribing of cardboard substrates is described as a method for fabricating carbon electrodes modified with metallic nanoparticles. The first scribing step patterned a cardboard substrate (promoting the formation of porous carbon electrodes). The second step was included to produce metallic nanoparticles via a chemical reduction process of cations from an aqueous solution. For these experiments, the effects of copper, silver, nickel, cobalt, zinc, and gold were evaluated considering their effect on the electrical properties and the composition of the carbon materials produced. These experiments revealed that, despite significant changes in resistance (from 138±7 Ω for plain electrodes to just 53±3 Ω for Au-modified electrodes), only marginal changes were observed in the morphology or composition of the material produced (IG/ID ranged from 1.2±0.3 for the plain cardboard to 1.8±0.3 for the cobalt-modified electrodes). To demonstrate the applicability of the proposed strategy, Au-modified electrodes were assembled into electrochemical sensors and applied to measure the metabolic activity of live microorganisms in various commercial samples, requiring only 100 μL of sample and 10 min of incubation time.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202300056","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139223502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Optofluidic System for Monitoring Fluorescently Activated Protein Biomarkers 监测荧光活化蛋白生物标记物的光流体系统

Analysis & sensing Pub Date : 2023-11-27 DOI: 10.1002/anse.202300064

Md Fahim Al Fattah, Hesam Abouali, Seied Ali Hosseini, Jian Yin, Asif Abdullah Khan, Hamid Aghamohammadi, Prof. Mahla Poudineh, Prof. Dayan Ban

{"title":"An Optofluidic System for Monitoring Fluorescently Activated Protein Biomarkers","authors":"Md Fahim Al Fattah, Hesam Abouali, Seied Ali Hosseini, Jian Yin, Asif Abdullah Khan, Hamid Aghamohammadi, Prof. Mahla Poudineh, Prof. Dayan Ban","doi":"10.1002/anse.202300064","DOIUrl":"10.1002/anse.202300064","url":null,"abstract":"The ability to monitor protein biomarkers at clinically relevant concentrations is a powerful approach that provides insights into health status. The synergistic combination of microfluidics and photonics (optofluidic) has emerged as a new means to achieve this capability for detection and manipulation of biological samples. Here in this work, we demonstrate an optofluidic device which integrates the detection and the particle-focusing components to facilitate on-chip measurement of protein levels. With this design, we use a laser-induced fluorescence technique for the direct measurement of protein levels on magnetic bead complexes tagged with fluorescein isothiocyanate (FITC) fluorophore. The developed system was employed for the detection of human immunoglobulin G (IgG) as a model protein within a range of 0–20 μg/mL, showing an ability to resolve the fluorescence signal from different IgG concentrations down to 5.4 nM (0.81 μg/mL). The selectivity in detecting specific IgG target was tested by comparing the fluorescence signal levels from other interfering proteins such as bovine serum albumin (BSA) and human IgM. Although our system was designed for detecting IgG protein, this optofluidic device can be a powerful platform for the rapid detection of a diverse range of biomarkers, including viral pathogens retaining adequate signal sensitivity and selectivity.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139231267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural Elucidation and Relative Quantification of Fatty Acid Double Bond Positional Isomers in Biological Tissues Enabled by Gas-Phase Charge Inversion Ion/Ion Reactions 气相电荷反转离子/离子反应实现生物组织中脂肪酸双键位置异构体的结构阐释和相对定量

Analysis & sensing Pub Date : 2023-11-13 DOI: 10.1002/anse.202300063

Dr. Julia R. Bonney, Dr. Boone. M Prentice

{"title":"Structural Elucidation and Relative Quantification of Fatty Acid Double Bond Positional Isomers in Biological Tissues Enabled by Gas-Phase Charge Inversion Ion/Ion Reactions","authors":"Dr. Julia R. Bonney, Dr. Boone. M Prentice","doi":"10.1002/anse.202300063","DOIUrl":"10.1002/anse.202300063","url":null,"abstract":"Fatty acids (FAs) contain a vast amount of structural diversity, and differences in fatty acid structure have been associated with various disease states. Accurate identification and characterization of fatty acids is critical to fully understand the biochemical roles these compounds play in disease progression. Conventional tandem mass spectrometry (MS/MS) workflows do not provide sufficient structural information, necessitating alternative dissociation methods. Gas-phase charge inversion ion/ion reactions can be used to alter the ion type subjected to activation to provide improved or complementary structural information. Herein, we have used an ion/ion reaction between fatty acid (FA) anions and magnesium tris-phenanthroline [Mg(Phen)3] dications to promote charge remote fragmentation of carbon-carbon bonds along the fatty acid chain, allowing for localization of carbon-carbon double bond (C=C) positions to successfully differentiate monounsaturated fatty acid isomers. Relative quantification was also performed to obtain the relative abundance of fatty acid isomers in different biological tissues. For example, the relative abundance of FA 18 : 1 (9) was determined to vary across regions of rat brain, rat kidney, and mouse pancreas, and FA 16 : 1 (9) was found to have a higher relative abundance in the dermis layer compared to the sebaceous glands in human skin tissue.","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136283469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0