双金属纳米粒子作为免疫传感器中的电化学标签,用于检测临床相关的生物标记物

IF 3.4 Q2 CHEMISTRY, ANALYTICAL
David Valero-Calvo, Francisco Javier García-Alonso, Alfredo de la Escosura-Muñiz
{"title":"双金属纳米粒子作为免疫传感器中的电化学标签,用于检测临床相关的生物标记物","authors":"David Valero-Calvo,&nbsp;Francisco Javier García-Alonso,&nbsp;Alfredo de la Escosura-Muñiz","doi":"10.1002/anse.202400017","DOIUrl":null,"url":null,"abstract":"<p>Electrochemical immunosensors have emerged in the last years as outstanding analytical systems for the detection of analytes of clinical interest. As alternative to the traditional enzymatic labels, the use of nanoparticles and especially bimetallic ones has gained increased attention thanks to their advantages related to the higher simplicity, stability and sensitivity offered. Main routes for the detection of such nanoparticle labels are based on i) dissolution of the nanoparticle into the corresponding metal ions followed by voltammetric detection; ii) taking advantage of the electrocatalytic effect of the metals towards secondary reactions; and iii) taking advantage of their electrochemiluminescence properties.</p>","PeriodicalId":72192,"journal":{"name":"Analysis & sensing","volume":"4 5","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202400017","citationCount":"0","resultStr":"{\"title\":\"Bimetallic Nanoparticles as Electrochemical Labels in Immunosensors for the Detection of Biomarkers of Clinical Interest\",\"authors\":\"David Valero-Calvo,&nbsp;Francisco Javier García-Alonso,&nbsp;Alfredo de la Escosura-Muñiz\",\"doi\":\"10.1002/anse.202400017\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Electrochemical immunosensors have emerged in the last years as outstanding analytical systems for the detection of analytes of clinical interest. As alternative to the traditional enzymatic labels, the use of nanoparticles and especially bimetallic ones has gained increased attention thanks to their advantages related to the higher simplicity, stability and sensitivity offered. Main routes for the detection of such nanoparticle labels are based on i) dissolution of the nanoparticle into the corresponding metal ions followed by voltammetric detection; ii) taking advantage of the electrocatalytic effect of the metals towards secondary reactions; and iii) taking advantage of their electrochemiluminescence properties.</p>\",\"PeriodicalId\":72192,\"journal\":{\"name\":\"Analysis & sensing\",\"volume\":\"4 5\",\"pages\":\"\"},\"PeriodicalIF\":3.4000,\"publicationDate\":\"2024-05-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anse.202400017\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Analysis & sensing\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/anse.202400017\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analysis & sensing","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/anse.202400017","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0

摘要

近年来,电化学免疫传感器已成为检测临床相关分析物的杰出分析系统。作为传统酶标记的替代品,纳米粒子,尤其是双金属纳米粒子的使用越来越受到关注,这是因为它们具有更简便、更稳定和更灵敏的优点。检测此类纳米粒子标签的主要方法有:i) 将纳米粒子溶解到相应的金属离子中,然后进行伏安检测;ii) 利用金属对二次反应的电催化效应;iii) 利用其电化学发光特性。在此背景下,本综述介绍了在免疫传感器中使用双金属纳米粒子作为电化学标签检测临床分析物的最新趋势。本综述介绍了在免疫传感器中使用双金属纳米粒子作为电化学标签检测临床感兴趣的分析物的最新趋势,并提供了分析性能和文献中发现的主要方法的重要概述,最后介绍了该领域的未来展望和前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Bimetallic Nanoparticles as Electrochemical Labels in Immunosensors for the Detection of Biomarkers of Clinical Interest

Bimetallic Nanoparticles as Electrochemical Labels in Immunosensors for the Detection of Biomarkers of Clinical Interest

Electrochemical immunosensors have emerged in the last years as outstanding analytical systems for the detection of analytes of clinical interest. As alternative to the traditional enzymatic labels, the use of nanoparticles and especially bimetallic ones has gained increased attention thanks to their advantages related to the higher simplicity, stability and sensitivity offered. Main routes for the detection of such nanoparticle labels are based on i) dissolution of the nanoparticle into the corresponding metal ions followed by voltammetric detection; ii) taking advantage of the electrocatalytic effect of the metals towards secondary reactions; and iii) taking advantage of their electrochemiluminescence properties.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
2.60
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信