Aggregate (Hoboken, N.J.)最新文献

{"title":"Inside Front Cover: Fluorescence imaging-guided lipid droplets-localized photodynamic therapy","authors":"Shan Wang,&nbsp;Qiang Wang,&nbsp;Yang Lv,&nbsp;Zhe Liu,&nbsp;Kippeum Lee,&nbsp;Dongeun Kim,&nbsp;Miae Won,&nbsp;Jianliang Shen,&nbsp;Jong Seung Kim","doi":"10.1002/agt2.737","DOIUrl":"https://doi.org/10.1002/agt2.737","url":null,"abstract":"<p>This review focuses on the lipid droplets (LDs)-localized chemical chromophores for photodynamic therapy. It highlights the design principles, performance, and biomedical applications of these photosensitizers (PSs). Especially, the cell death pathways induced by these tools are introduced. These targetable PSs guard our health by destroying the LDs of cancer cells, just as soldiers protect our cities from alien invasion by destroying the energy cores of alien airships (e665).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 1","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.737","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143117747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Front Cover: Near-room-temperature π-conjugated nematic liquid crystals in molecules with a flexible seven-membered ring structure","authors":"Riki Iwai,&nbsp;Hiroyuki Yoshida,&nbsp;Yuki Arakawa,&nbsp;Shunsuke Sasaki,&nbsp;Yuuto Iida,&nbsp;Kazunobu Igawa,&nbsp;Tsuneaki Sakurai,&nbsp;Satoshi Suzuki,&nbsp;Masatoshi Tokita,&nbsp;Junji Watanabe,&nbsp;Gen-ichi Konishi","doi":"10.1002/agt2.736","DOIUrl":"https://doi.org/10.1002/agt2.736","url":null,"abstract":"<p>This study provides a novel molecular design methodology that dramatically decreases the isotropization temperature of π-conjugated nematic liquid crystals (NLC). In addition, a large-area electric-field-responsive fluorescent switch device with a sub-millisecond response time is demonstrated using a luminescent NLC and a liquid crystal display cell. The era of alignment of liquid crystalline organic semiconductors as desired has begun (e660).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 1","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.736","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143117746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inside Back Cover: Revealing enhanced dilution effect of conjugated polymers in partially miscible blends","authors":"Hongbo Chen,&nbsp;Ming Hu,&nbsp;Yuehua Zhao,&nbsp;Kaixuan Lyu,&nbsp;Yushuai Xu,&nbsp;Yuansheng Sun,&nbsp;Zhiyuan Xie,&nbsp;Jinying Huang,&nbsp;Dapeng Wang","doi":"10.1002/agt2.738","DOIUrl":"https://doi.org/10.1002/agt2.738","url":null,"abstract":"<p>A counterintuitive optimized dilution effect is unveiled for conjugated polymers in blends. In partially miscible blends, these polymers are more dilute in the majority phase; however, in fully miscible blends, the high miscibility fosters extended chain conformations that undermine dilution. These revelations will inform the design of future generations of polymer light-emitting diodes (e649).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 1","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.738","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143117885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Back Cover: Droplets Cas13a-RPA measurement delineates potential role for plasma circWDR37 in colorectal cancer","authors":"Jingsong Xu,&nbsp;Li Cao,&nbsp;Shuang Yang,&nbsp;Ying Jian,&nbsp;Yu Liu,&nbsp;Zhen Shen,&nbsp;Qian Liu,&nbsp;Xiang Chen,&nbsp;Min Li,&nbsp;Shun Li,&nbsp;Xiaolei Zuo,&nbsp;Min Li,&nbsp;Hua Wang","doi":"10.1002/agt2.739","DOIUrl":"https://doi.org/10.1002/agt2.739","url":null,"abstract":"<p>This study identified circWDR37 as a promising biomarker for the early diagnosis and prognostic prediction of colorectal cancer (CRC). A detection platform, termed μDCR, was developed utilizing polyethylene glycol 8000 and dextran-10 to enhance fluorescence and improve detection sensitivity. It is anticipated that μDCR will serve as an optimal method for noninvasive CRC screening (e663).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 1","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.739","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143117356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inside Front Cover: Complexity made easy: Aggregation-induced emission small molecules for cancer diagnosis and phototherapies","authors":"Luojia Chen,&nbsp;Si-Ling Chen,&nbsp;Yuncong Yuan,&nbsp;Xiang Leng,&nbsp;Xiaoyu Xu,&nbsp;Jingyuan Chen,&nbsp;Jiayi Shi,&nbsp;Kun Qian,&nbsp;Yuanlong Xie,&nbsp;Qihang Ding,&nbsp;Zhen Cheng,&nbsp;Meijia Gu","doi":"10.1002/agt2.717","DOIUrl":"https://doi.org/10.1002/agt2.717","url":null,"abstract":"<p>The rising popularity of photosensitizers has greatly transformed traditional cancer diagnosis and phototherapeutic strategies. This review highlights the latest advances in small molecule photosensitizers with aggregation-induced emission (AIE) for cancer theranostics, following the principle of “Complexity made easy.” This study emphasizes on simplicity, expeditiousness, and safety, as it aims to advance cancer research (e657).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"5 6","pages":""},"PeriodicalIF":13.9,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.717","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142861097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Front Cover: Reconfigurable liquids enabled by dynamic covalent chemistry","authors":"Kaijuan Li,&nbsp;Yuzheng Luo,&nbsp;Yunhui Wen,&nbsp;Wenrui Shan,&nbsp;Shaowei Shi","doi":"10.1002/agt2.716","DOIUrl":"https://doi.org/10.1002/agt2.716","url":null,"abstract":"<p>The formation, assembly and jamming of nanoparticle surfactants (NPS) by the co-assembly between polydopamine nanoparticles and poly(styrene-<i>co</i>-methacrylamidophenylboronic acid) at the oil-water interface is presented. Taking advantage of the photothermal property of PDA NPs, the thermal responsiveness of NPSs can be triggered upon near-infrared irradiation, allowing the welding of droplets and offering a straightforward to construct modular droplet devices (e621).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"5 6","pages":""},"PeriodicalIF":13.9,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.716","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142861098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Back Cover: Microtubule polymerization induced by iridium-fullerene photosensitizers for cancer immunotherapy via dual-reactive oxygen species regulation strategy","authors":"Xiao-Xiao Chen,&nbsp;Kun Peng,&nbsp;Xi Chen,&nbsp;Zheng-Yin Pan,&nbsp;Qing-Hua Shen,&nbsp;Yu-Yi Ling,&nbsp;Jian-Zhang Zhao,&nbsp;Cai-Ping Tan","doi":"10.1002/agt2.719","DOIUrl":"https://doi.org/10.1002/agt2.719","url":null,"abstract":"<p>The constructive chemical combination of iridium(III) complexes and C₆₀ moiety endows <b>Ir-C₆₀1</b> with dual reactive oxygen species (ROS) regulation abilities and promising antitumor photo-immunotherapeutic activities. In the dark, <b>Ir-C₆₀1</b> serves as ROS scavengers to reverse dysfunctional T cells. Upon photo irradiation, <b>Ir-C₆₀1</b> can produce various ROS and oxidize tubulin to exert efficient photo-immunotherapeutic effects through multiple antitumor pathways (e623).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"5 6","pages":""},"PeriodicalIF":13.9,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.719","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142861100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inside Back Cover: The careful selection of zwitterionic nanoparticle coating results in rapid and efficient cell labeling for imaging-based cell tracking","authors":"Nicholas D. Calvert,&nbsp;Luciana Yu,&nbsp;Olivia C. Sehl,&nbsp;Julia J. Gevaert,&nbsp;Natasha N. Knier,&nbsp;Angelie Rivera-Rodriguez,&nbsp;Clara S. Goulet,&nbsp;Nitara Fernando,&nbsp;Samantha Flood,&nbsp;Carlos M. Rinaldi-Ramos,&nbsp;Paula J. Foster,&nbsp;Adam J. Shuhendler","doi":"10.1002/agt2.718","DOIUrl":"https://doi.org/10.1002/agt2.718","url":null,"abstract":"<p>In the current work, superparamagnetic iron oxide nanoparticles coated with zwitterionic ligands improved cell loading and retention for Magnetic Particle Imaging. The best-performing surface coating enabled high cell uptake with short incubation times and stable in vivo imaging over 7 days. These advancements improve the sensitivity and duration of cell tracking by enhancing nanoparticle loading into a variety of cell types (e609).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"5 6","pages":""},"PeriodicalIF":13.9,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.718","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142861099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring toward a Broader Space: The Upcoming New Voyage of Aggregate","authors":"Ben Zhong Tang","doi":"10.1002/agt2.714","DOIUrl":"https://doi.org/10.1002/agt2.714","url":null,"abstract":"&lt;p&gt;Developing a top-notch journal is a great yet challenging voyage. To sail steadily and speedily toward the ultimate destination, the ship of &lt;i&gt;Aggregate&lt;/i&gt; needs a compass and an engine. The compass is the original aspiration of publishing high-quality research accomplishments on aggregate science, and the engine is the enthusiastic support from the scientific community, including the authors, reviewers, readers, and editorial board members.&lt;/p&gt;&lt;p&gt;In the past four years, &lt;i&gt;Aggregate&lt;/i&gt; enjoyed a successful takeoff followed by high-speed sailing. Now it has arrived at the transition point of the next-stage shipping line, where we should summarize the previous performance and envision the upcoming new voyage toward a broader space.&lt;/p&gt;&lt;p&gt;In 2024, &lt;i&gt;Aggregate&lt;/i&gt; received the 2nd Journal Impact Factor (JIF) of 13.9, maintaining a Q1 ranking in three categories: “Chemistry, Multidisciplinary”, “Chemistry, Physical”, and “Materials Science, Multidisciplinary” based on the Journal Citation Reports (JCR) 2024 published by Clarivate Analytics. For the first time, &lt;i&gt;Aggregate&lt;/i&gt; received a CiteScore&lt;sup&gt;TM&lt;/sup&gt; of 17.4, ranking top 5% and 6% in the categories of “Chemistry: Chemistry (Miscellaneous)” and “Materials Science, Materials Chemistry,” respectively.&lt;/p&gt;&lt;p&gt;Besides the impressive journal metrics mentioned above, 2024 is a year of rapid expansion for &lt;i&gt;Aggregate&lt;/i&gt; in terms of a significant increase in the numbers of manuscript submissions and paper publications, a broader scope of the journal, a stronger editorial board team, and a wider range of authors and reviewers (Figure 1). So proud to say that the “compass” is upgraded, and the “engine” is further empowered!&lt;/p&gt;&lt;p&gt;To date, &lt;i&gt;Aggregate&lt;/i&gt; has received manuscript submissions from international authors in 38 countries/regions. In 2024, &lt;i&gt;Aggregate&lt;/i&gt; has published 185 papers until November 13, 2024 (Figure 1A). Considering the continuous increase in the number of published papers, we have decided to shift &lt;i&gt;Aggregate&lt;/i&gt; from the current bimonthly journal to a monthly journal from 2025. To maintain high quality with increased quantity, we will set a higher standard for prescreening, while keeping our tradition of fast and fair peer review. In the past 12 months, the acceptance rate has gradually dropped and the average times from the submission to the first and final decisions have been shortened to 12 and 25 days, respectively.&lt;/p&gt;&lt;p&gt;&lt;i&gt;Aggregate&lt;/i&gt; aims to grow into a comprehensive and multidisciplinary journal in the area of aggregate science, covering significant advancements and innovative breakthroughs in a wide range of research fields, including chemistry, materials science, physics, engineering, nanotechnology, biology, life science, and so on. &lt;i&gt;Aggregate&lt;/i&gt; encourages paradigm shift in research philosophy and promotes the study of complex systems and processes at higher structural hierarchy across disciplinary boundaries. We emphasize that all the studies beyond","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"5 6","pages":""},"PeriodicalIF":13.9,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.714","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142861865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Front Cover: Steric hindrance induced low exciton binding energy enables low-driving-force organic solar cells","authors":"Tianyu Hu,&nbsp;Xufan Zheng,&nbsp;Ting Wang,&nbsp;Aziz Saparbaev,&nbsp;Bowen Gao,&nbsp;Jingnan Wu,&nbsp;Jingyi Xiong,&nbsp;Ming Wan,&nbsp;Tingting Cong,&nbsp;Yuda Li,&nbsp;Ergang Wang,&nbsp;Xunchang Wang,&nbsp;Renqiang Yang","doi":"10.1002/agt2.681","DOIUrl":"https://doi.org/10.1002/agt2.681","url":null,"abstract":"<p>This article focuses on the regulation of steric hindrance effect on the exciton binding energy of Y-series non-fullerene acceptors. The introduction of bulk cyclohexyl group in the side chains modulates inter- and intramolecular interactions of acceptors, thereby influencing the exciton binding energy and ultimately enhancing the energy conversion efficiency of organic solar cells (e632).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"5 5","pages":""},"PeriodicalIF":13.9,"publicationDate":"2024-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.681","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}