Aggregate (Hoboken, N.J.)最新文献

{"title":"Efficient Chiral Ultraviolet and Deep-Blue Materials for High-Performance Circularly Polarized OLEDs","authors":"Letian Xu,&nbsp;Yan Li,&nbsp;Hao Liu,&nbsp;Nuoling Qiu,&nbsp;Hui Chen,&nbsp;Yinhao Luo,&nbsp;Heping Shi,&nbsp;Ben Zhong Tang,&nbsp;Zujin Zhao","doi":"10.1002/agt2.70240","DOIUrl":"https://doi.org/10.1002/agt2.70240","url":null,"abstract":"<p>High-performance circularly polarized organic light-emitting diodes (CP-OLEDs) with ultraviolet and deep-blue circularly polarized electroluminescence (CP-EL) are important for 3D displays, but designing short-wavelength circularly polarized luminescence (CPL) materials remains a significant challenge. Herein, a series of ultraviolet and deep-blue CPL materials was developed, successfully integrating high photoluminescence quantum yields with efficient high-level reverse intersystem crossing (hRISC) properties. Efficient ultraviolet and deep-blue CP-OLEDs are created by utilizing these chiral materials as emitters, providing maximum external quantum efficiencies (<i>η</i>_ext,maxs) of 6.7% at 398 nm (full-width at half-maximum [FWHM] = 44 nm) and 10.8% at 454 nm (FWHM = 68 nm) with obvious CP-EL. Furthermore, by adopting these chiral materials as sensitizers or functional layers, well-developed achiral multi-resonance thermally activated delayed fluorescence green and yellow emitters are enabled to generate obvious CP-EL with large dissymmetry factors and excellent EL performance (<i>η</i>_exts = 34.5% and 35.3%, FWHM = 42 and 40 nm). These results demonstrate that the developed new ultraviolet and deep-blue chiral materials can be used not only as emitters for ultraviolet and deep-blue CP-OLEDs, but also as sensitizers and functional layers to furnish a simple and universal way of achieving efficient narrow-spectrum CP-OLEDs with achiral emitters.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"7 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70240","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145983878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic Control of Two-Component Aggregation and Color-Tunable Emission via Charge-Transfer Coassembly","authors":"Huiting Mao,&nbsp;Xinqi Ge,&nbsp;Jiahui Guo,&nbsp;Zhibo Gong,&nbsp;Na Ding,&nbsp;Shijuan Liu,&nbsp;Guo-Gang Shan,&nbsp;Ruinian Hua","doi":"10.1002/agt2.70241","DOIUrl":"https://doi.org/10.1002/agt2.70241","url":null,"abstract":"<p>Aggregation-induced emission luminogens (AIEgens) have become a vital class of functional materials for optoelectronic and biomedical applications. Extending AIE behavior from single-component to two-component systems opens a new avenue for modulating emission through intermolecular interactions, yet it also introduces substantial complexity in understanding and controlling the aggregation process. In particular, elucidating how multicomponent molecular packing governs macroscopic photophysical behavior remains a central challenge. Herein, we constructed four distinct charge-transfer (CT) cocrystals through the coassembly of electron-rich dibenzo-heterocyclic donors and electron-deficient 1,2,4,5-tetracyanobenzene (TCNB) acceptors. The cocrystallization process allows precise manipulation of the dynamic aggregation pathway by tuning the DMSO/H₂O ratio. Intriguingly, the morphology evolves from amorphous aggregates to rod-like and finally to needle-like microcrystals, showing a nonmonotonic size variation with increasing water content, accompanied by a gradual enhancement of fluorescence intensity. The four CT complexes exhibit wide emission tunability from green to orange-red, and notably, the AIE-active DBT/TCNB pair enables a practical demonstration in water-jet rewritable encryption paper. Overall, this work establishes a simple yet effective paradigm for designing high-performance solid-state emitters, while unveiling fundamental principles that govern the controllable molecular assembly in multicomponent luminescent systems.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"7 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70241","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145983877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Dual-Locking G-Quadruplex DNA Targeting Strategy Based on a Tumor-Accumulating Porphyrin-Ruthenium(II) Conjugate for Type I Photodynamic Therapy","authors":"Qiong Wu,&nbsp;Wan-Wan Hong,&nbsp;Jia-Hui Shi,&nbsp;Ren-Shan Deng,&nbsp;Wan-Qi Chen,&nbsp;Chan-Ling Yuan,&nbsp;Wen-Jie Mei","doi":"10.1002/agt2.70239","DOIUrl":"https://doi.org/10.1002/agt2.70239","url":null,"abstract":"<p>The hypoxic tumor microenvironment severely limits the effectiveness of photodynamic therapy (PDT) in hepatocellular carcinoma (HCC). To overcome this limitation, we designed and synthesized a dual-functional photosensitizer, PorRu, by conjugating a porphyrin unit with a ruthenium(II) polypyridyl complex through a flexible alkyl chain. PorRu is engineered to achieve specific accumulation in HCC cells and “dual-lock” binding with G-quadruplex DNA (G4 DNA). It demonstrated approximately 3–6 folds higher photocytotoxicity against HCC cells compared to its individual components, owing to enhanced tumor targeting and improved Type I photochemical reactivity. Unlike conventional oxygen-dependent PDT, PorRu efficiently generates reactive oxygen species (ROS) under near-infrared irradiation, directly oxidizing guanine bases in G4 DNA and causing extensive oxidative damage under both normoxic and hypoxic conditions. The ROS burst induces severe oxidative stress, mitochondrial dysfunction, and the release of mitochondrial DNA (mtDNA), ultimately activating the inflammasome and triggering pyroptosis. In vivo studies validated the potent tumor-suppressive capability of PorRu, highlighting its potential to circumvent hypoxia-induced therapy resistance. This work not only presents PorRu as a promising agent for precise HCC targeting but also offers a novel strategy to enhance PDT efficacy against hypoxic tumors.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"7 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70239","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145970071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Hypoxia-Responsive Near-Infrared Phosphorescence Nanoprobe for High-Sensitive Detection of Tumor Cells and Imaging of Colorectal Cancer In Situ","authors":"Jian Chen,&nbsp;Huamin Lan,&nbsp;Sensen Zhou,&nbsp;Weizhi Chen,&nbsp;Xu Zhen,&nbsp;Xiqun Jiang","doi":"10.1002/agt2.70243","DOIUrl":"https://doi.org/10.1002/agt2.70243","url":null,"abstract":"<p>Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world, exhibiting persistently high mortality rates due to delayed diagnosis and imprecise lesion localization. Leveraging the prevalent hypoxic microenvironment characteristic of CRC lesions, this study innovatively developed a PEGylated iridium-based near-infrared (NIR) hypoxia nanoprobe, Ir-PEG. This nanoprobe can be activated in situ under hypoxic conditions, providing high-contrast imaging of colonic lesions, even though the intestine is inherently a low oxygen environment. In vitro evaluation demonstrated that Ir-PEG had excellent oxygen sensitivity, water solubility, and deep tissue penetration capability. These properties enabled Ir-PEG to achieve precise imaging of CRC in the native colonic microenvironment. Remarkably, in both in vitro and in vivo models, Ir-PEG achieved highly sensitive detection of cancer cell populations, and could detect as few as 10⁴ CT26 cells in vivo. In addition, the nanoprobe could successfully identify different tumor types based on differential oxygen consumption rates across various cancer cells, suggesting its potential to identify intratumoral heterogeneity. As a molecular imaging tool, Ir-PEG enabled early non-invasive detection of CRC with high sensitivity and specificity, and holding significant promise for clinical translation.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"7 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70243","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145983831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-Assembly Pathways of Carbazole-derived Macrocycles Into Nanotubular Architectures","authors":"Yingbo Lu,&nbsp;Luyao Jin,&nbsp;Jianan Jin,&nbsp;Jiaqi Xuan,&nbsp;Jiani Wang,&nbsp;Zibin Zhang,&nbsp;Qiuchengyi Ye,&nbsp;Hua Yang,&nbsp;Zhigang Ni,&nbsp;Feng Wang,&nbsp;Shijun Li","doi":"10.1002/agt2.70231","DOIUrl":"https://doi.org/10.1002/agt2.70231","url":null,"abstract":"<p>Cooperative self-assembly based on multiple non-covalent interactions is ubiquitous in nature, yet the rational design of artificial cooperative systems remains challenging. Here we synthesize two carbazole derivatives, <b>CbzE</b> (with an ester group) and <b>CbzA</b> (with amide groups), to investigate how hydrogen bonding (HB) and halogen bonding (XB) jointly guide self-assembly into nanotubular supramolecular polymers. Using 1,4-diiodotetrafluorobenzene (DITFB) as XB donor or diplatinum(II) as linker, two types of [4 + 4] macrocycles are constructed and characterized by high-resolution mass spectrometry, ultraviolet-visible, infrared, and atomic force microscopy. <b>CbzA</b>, benefiting from strong HB, cooperatively assembles with <b>DITFB</b> into nanofibers and nanotubes, whereas <b>CbzE</b>, lacking amide groups, forms only disordered aggregates. Pt(II) coordination disrupts HB networks and redirects <b>CbzA</b> toward lateral aggregation, underscoring the sensitivity of assembly pathways to the balance of interactions. Remarkably, nanotubular <b>CbzA</b> + <b>DITFB</b> structures disassemble rapidly under trifluoroacetic acid vapor but are restored by triethylamine, demonstrating a reversible gel–sol–gel transition. This orthogonal acid/base responsiveness highlights the tunable and dynamic features of cooperative HB/XB systems. Overall, these results reveal the critical role of HB and XB cooperativity in directing ordered architectures and provide new design principles for intelligent supramolecular polymers with stimuli-responsive functions.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 12","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70231","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145779347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multichromophoric Macrocycle Nanoparticles for Mitigating Cyanine Limit and Efficient Aqueous Photocatalysis via Sequential Energy Transfer","authors":"Vidushi Gupta,&nbsp;Sanchita Sengupta","doi":"10.1002/agt2.70232","DOIUrl":"https://doi.org/10.1002/agt2.70232","url":null,"abstract":"<p>Cyanine dyes, despite their strong near-infrared (NIR) absorption, often undergo symmetry-breaking Peierls’ transitions in water known as the “cyanine limit,” resulting in suboptimal optical properties. In this work, we present a strategy to overcome this limitation by entrapping cyanine dye (<b>Cy746</b>) within the micellar nanoparticle (<b>Np@M1-Cy746</b>) of a bichromophoric [1+1] macrocycle <b>M1</b> comprising of perylene diimide (PDI) and aza-BODIPY (Aza) that exhibits Förster resonance energy transfer (FRET), formed from an amphiphilic polymer 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)]. This approach not only stabilizes the cyanine dye but also enables two-step FRET from PDI to Aza of the macrocycle to <b>Cy746</b>, resulting in panchromatic absorption, enhanced NIR emission, and achieved near-white light emission. The micellar FRET assembly <b>Np@M1-Cy746</b> also serves as a ratiometric temperature sensor with a sensitivity of 0.0379%°C⁻¹ and was utilized as a supramolecular photocatalyst in aqueous-phase photocatalytic Knoevenagel condensation of benzaldehyde and malononitrile. The two-step FRET process in <b>Np@M1-Cy746</b> enabled its superior photocatalytic performance compared to the micelle of only <b>M1</b> (<b>Np@M1</b>), which shows one-step FRET. This study offers a distinct approach for constructing multichromophoric macrocycle nanoparticles in aqueous media, leveraging upon its sequential energy transfer to achieve efficient and scalable photocatalytic transformation.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 12","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70232","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145772544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The First 5 Years of Aggregate: Charting the Course for the Future of Aggregate Science","authors":"Ben Zhong Tang","doi":"10.1002/agt2.70234","DOIUrl":"https://doi.org/10.1002/agt2.70234","url":null,"abstract":"<p><i>Aggregate</i> celebrates its fifth anniversary this year. The journal has established itself as a leading platform for breakthroughs in aggregology—a field dedicated to the science of aggregate systems beyond isolated molecules. In this Editorial, we reflect on the journey so far and map out the exciting path forward.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 12","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70234","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145772545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alkoxy Chain Engineering Enables Dual-Mode Temperature-Activated Phosphorescence in Neutral Manganese(II) Complexes","authors":"Yanyan Qin,&nbsp;Zinan Wu,&nbsp;Mingbin Lian,&nbsp;Pengfei She,&nbsp;Wai-Yeung Wong","doi":"10.1002/agt2.70236","DOIUrl":"https://doi.org/10.1002/agt2.70236","url":null,"abstract":"<p>Temperature-responsive luminescent materials hold great potential for applications in various advanced photoelectronic fields. However, realizing dual-mode, temperature-activated luminescence within a single molecular system remains a significant challenge. Here, two neutral Mn(II) complexes with dual-mode temperature-activated luminescent properties have been successfully synthesized by an alkoxy chain engineering strategy. At room temperature, these complexes are strongly emission-quenched. Reducing or increasing temperature triggers pronounced luminescence enhancement, due to the prohibition of thermal population to the upper lying quenching state or the removal of trace water molecules. Notably, this study provides the first definitive evidence of the dual-mode temperature-activated photoluminescent behavior in quartet excited states. Furthermore, simple digit-display patterns and anti-counterfeiting applications are demonstrated in this work.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 12","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70236","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145772309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Molecular Descriptor Guided Asymmetric Strategy for High Carrier-Mobility Light-Emitting Organic Semiconductors","authors":"Jie Liu,&nbsp;Qi Sun,&nbsp;Yanjun Shi,&nbsp;Tong Jiang,&nbsp;Xiaosong Shi,&nbsp;Jiali Liu,&nbsp;Jing Zhang,&nbsp;Yaxin Zhai,&nbsp;Yu Wang,&nbsp;Qian Peng,&nbsp;Wenping Hu,&nbsp;Yunqi Liu,&nbsp;Zhigang Shuai,&nbsp;Lang Jiang","doi":"10.1002/agt2.70224","DOIUrl":"https://doi.org/10.1002/agt2.70224","url":null,"abstract":"&lt;p&gt;Combining high mobility and high-efficiency luminescence in one material is challenging because of their contradictory design principles. Here, under the three-state exciton model, a molecular descriptor &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mi&gt;O&lt;/mi&gt;\u0000 &lt;mo&gt;=&lt;/mo&gt;\u0000 &lt;mo&gt;(&lt;/mo&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mo&gt;|&lt;/mo&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mi&gt;h&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;mo&gt;+&lt;/mo&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mi&gt;e&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mo&gt;|&lt;/mo&gt;\u0000 &lt;mo&gt;−&lt;/mo&gt;\u0000 &lt;mo&gt;|&lt;/mo&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mi&gt;h&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;mo&gt;−&lt;/mo&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mi&gt;e&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mo&gt;|&lt;/mo&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;mo&gt;)&lt;/mo&gt;\u0000 &lt;mo&gt;/&lt;/mo&gt;\u0000 &lt;mn&gt;2&lt;/mn&gt;\u0000 &lt;mi&gt;J&lt;/mi&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;annotation&gt;$O = ( {| {{t_h} + {t_e}| - |{t_h} - {t_e}} |} )/2J$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt; is proposed to quantitatively design materials with balanced luminescence and mobility in aggregated states, where a large &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mi&gt;O&lt;/mi&gt;\u0000 &lt;annotation&gt;$O$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt; would promise high crystalline photoluminescence quantum yield (PLQY) with small &lt;i&gt;J&lt;/i&gt; (excitonic coupling) and significant &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mi&gt;h&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;annotation&gt;${t_h}$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt; and &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mi&gt;e&lt;/mi&gt;\u0000 &lt;/msub&gt;\u0000 &lt;annotation&gt;${t_e}$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt; (hole and electron transfer integrals) would indicate high mobility. Through theoretical calculation and experimental validation, it is found that the asymmetric anthracene derivatives are quite effective in simultaneously achieving high ","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 12","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70224","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145772308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stereoisomerism-controlled Packing in Ladder-type Indacenodithieno[3,2-b]thiophene Crystals","authors":"Meenal Kataria,&nbsp;Masaki Nobuoka,&nbsp;Yusuke Tsutsui,&nbsp;Takayuki Tanaka,&nbsp;Rajendra Prasad Paitandi,&nbsp;Yuta Takemasa,&nbsp;Wookjin Choi,&nbsp;Shu Seki","doi":"10.1002/agt2.70230","DOIUrl":"https://doi.org/10.1002/agt2.70230","url":null,"abstract":"<p>Stereochemistry is a potent way to direct the molecular packing in condensed phases. Here, we synthesized the enantiopure, racemic, and achiral isomers of <i>p</i>-type small molecule, that is, indacenodithieno[3,2-<i>b</i>]thiophene, to understand the impact of stereochemistry on molecular packing and solid-state properties. In the solution state, the optical properties remain nearly identical among the isomers; however, a significant difference was observed in the condensed phase. X-ray diffraction pattern revealed enantiopure isomers were more tightly packed and exhibited strong π-stacking relative to their racemic and achiral counterparts. Two-dimensional arrangement of the stacked enantiopure isomers gives more dense-packed crystalline phases than an achiral analog, which is unusual anti-Wallach type condensed phases. The enantiopure one exhibited two times higher photoconductivity than its achiral or racemic analogues, as well as showing high electron spin polarizability (∼75%) with electrical current throughput (100 nA). The result highlights the role of stereochemistry as a key strategy to direct the condensed phase packing and properties in conjugated crystals.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 12","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70230","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145772579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}