Front Cover: Molecular Aggregates of Wheat Starch–Protein Systems: Structural Disruption and Engineered Digestibility via Non-Covalent Synergy

Abstract

This study deciphers how wheat proteins (gliadin/glutelin) form non-covalent aggregates with starch, disrupting its molecular order via hydrophobic and electrostatic forces. Integrating experiments and simulations, we reveal how these aggregates inhibit enzymatic digestion and enhance resistant starch content—enabling tailored glycemic control. The cover visualizes protein-starch synergy for engineering low-digestibility food matrices (e70115).