Yu. L. Krutskii, T. S. Gudyma, A. I. Aparnev, A. V. Loginov, T. M. Krutskaya, A. V. Ukhina, N. Yu. Cherkasova, O. V. Netskina, E. A. Maximovskiy
{"title":"Synthesis of β-SiC Using Nanofibrous Carbon","authors":"Yu. L. Krutskii, T. S. Gudyma, A. I. Aparnev, A. V. Loginov, T. M. Krutskaya, A. V. Ukhina, N. Yu. Cherkasova, O. V. Netskina, E. A. Maximovskiy","doi":"10.1134/S2635167624602663","DOIUrl":"10.1134/S2635167624602663","url":null,"abstract":"<p>The synthesis and study of the characteristics of β-phase silicon carbide powder is carried out. The compound is obtained by combining endothermic and exothermic reactions (carbothermic reduction of silicon dioxide and synthesis from simple substances) in an induction furnace in an atmosphere of nitrogen and carbon monoxide (CO). Nanofibrous carbon (NFC) is used as the reducing agent and carbide-forming reagent. This carbon agent is obtained as a result of the decomposition of light hydrocarbons. NFC is characterized by a high specific surface area (~150 m<sup>2</sup>/g) in comparison, for example, with carbon black (~50 m<sup>2</sup>/g). NFC is a fairly pure material and the impurity content in it does not exceed 1 wt %. Optimization of the synthesis conditions made it possible to obtain a single-phase product: cubic silicon carbide β-SiC. The powder had an average particle size of ~4 μm and a specific surface area of 7.7–8.4 m<sup>2</sup>/g. The resulting silicon carbide barely oxidizes when heated to 1000°C. Completion of the synthesis reaction is achieved for samples whose charge contained NFC, silicon oxide, and silicon powder in a molar ratio of 4 : 1 : 1, respectively. The optimal synthesis temperature is 1700–1900°C.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 1 supplement","pages":"S138 - S145"},"PeriodicalIF":0.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. V. Belaya, E. A. Maksimovskiy, A. N. Kolodin, A. A. Shapovalova
{"title":"Morphology and Wettability of Hexagonal BCxNy Films Prepared by Plasma-Enhanced Chemical Vapor Deposition from Trimethylamine Borane","authors":"S. V. Belaya, E. A. Maksimovskiy, A. N. Kolodin, A. A. Shapovalova","doi":"10.1134/S2635167624600780","DOIUrl":"10.1134/S2635167624600780","url":null,"abstract":"<p>Hexagonal boron carbonitride films are obtained by plasma-enhanced chemical vapor deposition using a mixture of trimethylamine borane ((<i>Me</i>)<sub>3</sub>N·BH<sub>3</sub>) vapor and nitrogen in the temperature range 100‒700°C. The influence of the synthesis temperature, generator frequency, and plasma power on the chemical composition, structure, and morphology of the films is studied. The films obtained at temperatures of 200–700 and 300–700°C and generator frequencies of 27.12 and 13.56 MHz, respectively, are formed by nanowalls. Up to 600°C, the nanowalls have a maze-like morphology. The length of the nanowalls and the distance between them can be adjusted by changing the synthesis conditions. Above 600°C, nanowalls with a wavy morphology are formed. The contact angle of the water wetting of 200-nm-thick films varied within 0°‒62°.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 1 supplement","pages":"S84 - S92"},"PeriodicalIF":0.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. V. Shcherbanyuk, S. I. Moiseev, M. Yu. Frolova, S. N. Golyandin, N. A Germanov, N. V. Ulin, N. V. Kalmykova
{"title":"Increase in the Intensity of Free Radical Processes of Tumor Cells by Silver Bisilicate Nanoparticles","authors":"A. V. Shcherbanyuk, S. I. Moiseev, M. Yu. Frolova, S. N. Golyandin, N. A Germanov, N. V. Ulin, N. V. Kalmykova","doi":"10.1134/S2635167624602274","DOIUrl":"10.1134/S2635167624602274","url":null,"abstract":"<p>The chemiluminescence intensity (CI) when normal and tumor cells of humans are exposed to nanostructured silver bisilicate Ag<sub>6</sub>Si<sub>2</sub>O<sub>7</sub> (silver atomic clusters, SACs) are measured. The following cell types are used: skin fibroblasts F022, mesenchymal stromal cells (MSCs) M032, multiple myeloma cells RPMI8226, and acute myelogenous leukemia cells KG1. The chemiluminescence parameters (total light sum (<b><i>S</i></b>) and the maximal light intensity (<i>I</i><sub>max</sub>)) of normal cells increase by 1.4–1.5 times after adding SACs compared to the reference values regardless of the SAC concentration. The <i>S</i> and <i>I</i><sub>max</sub> values for tumor cells are between 2.1 and 2.8 times higher than the reference values depending on the SACs dose. In the reference data the tumor cells show a higher slope ratio of the trailing edge of radiation pulse of the CI decrease curve (1.02–1.10) than the normal cells (0.67–0.72). SACs with a concentration of 2.0–3.0 µg/mL significantly decrease tumor cell viability and do not affect normal cells. A higher sensitivity to SACs corresponds to a higher CI level in the cells.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 1 supplement","pages":"S195 - S201"},"PeriodicalIF":0.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Verlov, O. Shashkova, I. Krutetskaya, L. Terekhina, S. Shatik, A. Pinevich, V. Burdakov, I. Kulakov, T. Shtam, A. Konevega, A. Stanzhevskii, M. Samoilovich
{"title":"Comparison of Pharmacokinetic Parameters and Biodistribution of Full-Size Antibodies and Nanoantibodies Specific to Human PD-L1","authors":"N. Verlov, O. Shashkova, I. Krutetskaya, L. Terekhina, S. Shatik, A. Pinevich, V. Burdakov, I. Kulakov, T. Shtam, A. Konevega, A. Stanzhevskii, M. Samoilovich","doi":"10.1134/S2635167624602742","DOIUrl":"10.1134/S2635167624602742","url":null,"abstract":"<p>The study of pharmacokinetic parameters and biodistribution of radiopharmaceuticals is the most important stage in the study of their effectiveness and safety for clinical usage. In the present work, a comparative study of <sup>125</sup>I-labeled full-size therapeutic antibodies to human PD-L1 and recombinant single-domain heavy-chain antibodies (VHH) specific to the same biomarker was conducted. A mouse model of the tumor process induced by transplantation of CT26-PD-L1 recombinant cells stably expressing human PD-L1 receptor on their surface was used. The half-life time for VHH was almost 10 times shorter than for full-size antibodies while both pharmaceuticals demonstrated the ability of specific accumulation in CT26-PD-L1 tumor. The route of excretion for both drugs was mainly through urine. An abnormally rapid decrease of VHH concentration in the blood of mice was noted at the first 5 min after the radioconjugate administration.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 1 supplement","pages":"S210 - S217"},"PeriodicalIF":0.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Yu. Nesterov, S. V. Zabotnov, D. V. Shuleiko, D. E. Presnov, O. I. Sokolovskaya, N. A. Smirnov, L. A. Golovan, P. K. Kashkarov
{"title":"Morphology and Stability of Composite Silicon–Silver Nanoparticles Produced by Laser Ablation in a Liquid","authors":"V. Yu. Nesterov, S. V. Zabotnov, D. V. Shuleiko, D. E. Presnov, O. I. Sokolovskaya, N. A. Smirnov, L. A. Golovan, P. K. Kashkarov","doi":"10.1134/S2635167624602729","DOIUrl":"10.1134/S2635167624602729","url":null,"abstract":"<p>The possibility of the liquid-phase laser synthesis of silver-decorated silicon nanoparticles with an average diameter of about 120 nm, a diameter dispersion of less than 40 nm, and a size of decorating Ag nanoclusters in the range from 5 to 15 nm is shown as a result of the picosecond laser ablation of silicon targets in a water-ethanol solution containing dissolved silver nitrate (AgNO<sub>3</sub>) crystals. At a fixed laser pulses exposure time, the morphology of the nanoparticles depends on the ratio of water and ethanol in the solution and the concentration of silver nitrate. It is demonstrated that the pH factor of the buffer medium has a direct influence on the stability and decorative coating properties of the produced nanoparticles.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 1 supplement","pages":"S50 - S58"},"PeriodicalIF":0.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combined Metalens for Detecting Optical Vortices and Polarization States","authors":"A. G. Nalimov, V. V. Kotlyar","doi":"10.1134/S2635167624602687","DOIUrl":"10.1134/S2635167624602687","url":null,"abstract":"<p>A metasurface, including a metalens, in a thin film of amorphous silicon for the visible range is considered. This metasurface enables the simultaneous determination of topological charges –1, 1, –2, and 2 and the direction of rotation of the polarization vector (clockwise or counterclockwise) in an axial superposition of four optical vortices with left- and right-handed circular polarization by measuring the intensity at several specified points at a certain distance from it. The metasurface is composed of two simpler metasurfaces, parts of which are assembled into a combined metasurface in a checkerboard pattern. To form a metalens, a binary zone plate is embedded into the metasurface. The working element of the metasurface (its meta-atom) is a binary subwavelength diffraction grating, the rotation angle of the polarization vector of which depends on the slopes of the lines.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 1 supplement","pages":"S59 - S67"},"PeriodicalIF":0.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Yu. Golovin, A. G. Divin, A. A. Samodurov, Yu. A. Zaharov, A. I. Tyurin, Yu. I. Golovin
{"title":"Nondestructive Testing of Polymer Composites with a Honeycomb Filler Based on the Root Mean Square Temperature Deviatiosn Recorded in the Process of Active Thermography","authors":"D. Yu. Golovin, A. G. Divin, A. A. Samodurov, Yu. A. Zaharov, A. I. Tyurin, Yu. I. Golovin","doi":"10.1134/S263516762460281X","DOIUrl":"10.1134/S263516762460281X","url":null,"abstract":"<p>Polymer composites and composites including nanoscale structural elements in particular are being increasingly applied in various fields of industry. One of the actively developing types of such materials is composites with a honeycomb filler. The specifics of applying these materials requires monitoring and defect detection. However, it is complicated by their anisotropy and significant heterogeneity. The work describes a method of nondestructive testing based on active scanning thermography with a linear heat source, which is suitable for the detection of subsurface defects in nanocomposites with a honeycomb filler. Experiments on model samples with artificially introduced defects are carried out. Mathematical methods and algorithms for defect identification on the basis of thermogram data are developed. Some sources of noise and errors are identified, and measures to reduce their impact are proposed.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 1 supplement","pages":"S175 - S182"},"PeriodicalIF":0.8,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Socio-Humanitarian Aspects of the Application of Nanobiotechnologies in the Health Care Industry","authors":"T. N. Gaeva, T. V. Smirnova, R. G. Vasilov","doi":"10.1134/S263516762460069X","DOIUrl":"10.1134/S263516762460069X","url":null,"abstract":"<p>This review is devoted to analyzing the different aspects of the application of nanobiotechnologies in the health care industry. An assessment of the socio-humanitarian risks that arise in contrast to the invaluable contribution of nanobiotechnologies in improving the health and quality of life of the population is carried out. A principle for the identification and systematization of emerging risks is proposed, taking into account prospects for the development of the transhumanistic strategy of human enhancement using nanotechnologies, which is increasingly popular abroad, together with other convergent technologies. The main factors explaining the lag in the formation of the regulatory framework for applying nanobiotechnologies compared to the pace of scientific and technological development of this area are identified.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 6","pages":"859 - 871"},"PeriodicalIF":0.8,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. P. Kuvirchenkova, T. N. Goleva, D. V. Sukhinov, Ya. E. Sergeeva, R. G. Vasilov
{"title":"Effect of C-Phycocyanin on Isolated Mitochondria","authors":"A. P. Kuvirchenkova, T. N. Goleva, D. V. Sukhinov, Ya. E. Sergeeva, R. G. Vasilov","doi":"10.1134/S2635167624602420","DOIUrl":"10.1134/S2635167624602420","url":null,"abstract":"<p>C-phycocyanin, a water soluble light-harvesting pigment-protein complex of the cyanobacteria photosynthetic apparatus, demonstrates antioxidant, antitumor, and anti-inflammatory effects, and is often used in medical studies. In this work, the effect of C-phycocyanin isolated from the cyanobacterium <i>Arthrospira platensis</i> on the bioenergetic parameters of rat-liver mitochondria is examined. It is shown that C-phycocyanin does not exhibit uncoupling, depolarization or inhibition of the respiratory chain action for isolated rat-liver mitochondria, does not reduce the rate of ATP synthesis, but does exhibit a strong antioxidant effect.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 6","pages":"1023 - 1029"},"PeriodicalIF":0.8,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. A. Gritsai, A. A. Kuzharov, V. A. Roldugin, V. V. Butova, A. V. Soldatov, M. A. Soldatov
{"title":"On the Electrochemical Synthesis of Superparamagnetic Iron Oxide Nanoparticles with Low Coercivity Using a Magnetic Field","authors":"M. A. Gritsai, A. A. Kuzharov, V. A. Roldugin, V. V. Butova, A. V. Soldatov, M. A. Soldatov","doi":"10.1134/S2635167624602250","DOIUrl":"10.1134/S2635167624602250","url":null,"abstract":"<p>An improved electrochemical method for the synthesis of superparamagnetic iron oxide nanoparticles (NPs) with low coercivity is presented, which provides a high yield and good potential for scalability. The electrochemical synthesis method is optimized by changing parameters such as the composition of the electrolyte solution, the configuration of the electrodes, sonication during the synthesis process, and the use of a magnetic field for the selective sampling of magnetic NPs from the reaction zone. The obtained NPs are studied by X-ray diffraction analysis, transmission electron microscopy, X-ray absorption spectroscopy, and vibrational magnetometry. The X-ray diffraction patterns show that the synthesized magnetic NPs are dominated by the cubic phase, and according to X-ray absorption spectroscopy data, iron is in the oxidation state Fe<sup>3+</sup>. Taken together, these results indicate the formation of the γ-Fe<sub>2</sub>O<sub>3</sub> phase. According to transmission electron microscopy and X-ray peak broadening data, the average particle size is 13 and 8.6 nm, respectively. Vibrational magnetometry measurements indicate a trend towards decreasing coercivity with decreasing particle size. The obtained magnetic NPs, due to their characteristics, can be applied in the field of biomedicine.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"19 6","pages":"1044 - 1050"},"PeriodicalIF":0.8,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143632373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}