Nanotechnologies in Russia最新文献_第6页

Synthesis and Characterization of Ruthenium Nanoparticles 钌纳米颗粒的合成与表征

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Nanotechnologies in Russia Pub Date : 2026-03-02 DOI: 10.1134/S2635167625601196

D. V. Korolev, M. V. Shumilo, M. V. Afonin

引用次数: 0

β-Amyloid: Structure, Properties, and Link with Alzheimer’s Disease β-淀粉样蛋白：结构、性质及其与阿尔茨海默病的关系

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Nanotechnologies in Russia Pub Date : 2026-03-02 DOI: 10.1134/S2635167625601159

E. V. Kuznetsova, A. P. Chistyakov, A. I. Kulebyakina, P. De, S. N. Chvalun

{"title":"β-Amyloid: Structure, Properties, and Link with Alzheimer’s Disease","authors":"E. V. Kuznetsova, A. P. Chistyakov, A. I. Kulebyakina, P. De, S. N. Chvalun","doi":"10.1134/S2635167625601159","DOIUrl":"10.1134/S2635167625601159","url":null,"abstract":"Under certain conditions, peptides and proteins are capable of conversion from their soluble native form to insoluble, highly ordered fibrillar aggregates. Alzheimer’s disease is a progressive neurodegenerative disease, whose development is accompanied by a steady decline in the patient’s condition, loss of the ability to live independently, and ultimately death. Currently, there are tens of millions of people in the world with Alzheimer’s disease, but there are still no effective methods for combating this disease. One of the key pathomorphological attributes of Alzheimer’s disease is the formation of senile plaques: accumulations of β‑amyloid fibrils, the main components of which are β-amyloid peptides (Aβ), having a molecular weight and length of about 4 kDa and 40 amino acid residues, respectively. The review is devoted to the structural features of Aβ peptides, the mechanism of their aggregation leading to the formation of various Aβ oligomeric forms, protofibrils, protofilaments, and ultimately fibrils, as well as their biological role and link with Alzheimer’s disease. Modern scientific approaches aimed at inhibiting Aβ peptide aggregation by the action of various inhibitors on Aβ monomers, Aβ oligomers, as well as the surface of formed Aβ protofilaments and fibrils, are considered.","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 6","pages":"647 - 681"},"PeriodicalIF":0.8,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1134/S2635167625601159.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147336086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial Properties of Cotton E-Textiles Modified with Graphene Oxide and Silver Nanoparticles 氧化石墨烯和纳米银改性棉质电子纺织品的抗菌性能

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Nanotechnologies in Russia Pub Date : 2026-03-02 DOI: 10.1134/S2635167625601251

S. A. Smagulova, F. D. Vasileva, L. A. Tarasova, Ya. A. Akhremenko, Z. I. Evseev

{"title":"Antimicrobial Properties of Cotton E-Textiles Modified with Graphene Oxide and Silver Nanoparticles","authors":"S. A. Smagulova, F. D. Vasileva, L. A. Tarasova, Ya. A. Akhremenko, Z. I. Evseev","doi":"10.1134/S2635167625601251","DOIUrl":"10.1134/S2635167625601251","url":null,"abstract":"This study investigates the bactericidal and fungicidal properties of graphene oxide flakes with an average lateral size of 1 μm and an oxygen content of ~45%, mildly oxidized graphene flakes with an average lateral size of 0.1 μm and an oxygen content of ~20%, and a silver nanoparticle–graphene oxide composite in aqueous suspensions and cotton textiles. It is shown that after 24 hours of microbial exposure to the graphene oxide flake suspension, Escherichia coli was reduced by 80%, Staphylococcus aureus by 40%, and Candida albicans by 100%, whereas the mildly oxidized graphene suspension eliminated E. coli and S. aureus by 100% but reduced C. albicans by only 40%. The use of silver nanoparticle–graphene oxide composites demonstrates more effective antimicrobial action, achieving 100% elimination of E. coli, S. aureus, and C. albicans within 24 hours of exposure. The antimicrobial efficacy of textiles treated with graphene oxide and mildly oxidized graphene against E. coli is similar and relatively high compared to their effectiveness against S. aureus and C. albicans. Textiles with silver nanoparticle–graphene oxide composites exhibited antimicrobial efficacy approximately twice as high as that of graphene oxide.","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 6","pages":"927 - 935"},"PeriodicalIF":0.8,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147335992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dependence of the Aggregation Time of Linear and Star-Shaped Block Copolymers of Poly-2-alkyl-5,6-dihydrooxazines in Aqueous Solutions 聚2-烷基-5,6-二氢恶嗪线状和星形嵌段共聚物在水溶液中聚合时间的依赖性

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Nanotechnologies in Russia Pub Date : 2026-03-02 DOI: 10.1134/S2635167625601822

A. P. Filippov, S. V. Rodchenko, T. Yu. Kirila, A. V. Tenkovtsev

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On the Role of DNA in CaCO3 Biomineralization: Influence on the Kinetics, Mesoscale Structure, and Morphology of Biogenic Minerals DNA在CaCO3生物矿化中的作用：对生物矿物的动力学、中尺度结构和形态的影响

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Nanotechnologies in Russia Pub Date : 2026-03-02 DOI: 10.1134/S2635167625601950

L. A. Ivanova, A. E. Baranchikov, Yu. E. Gorshkova, N. A. Verlov, A. A. Kulminskaya, D. V. Lebedev

{"title":"On the Role of DNA in CaCO3 Biomineralization: Influence on the Kinetics, Mesoscale Structure, and Morphology of Biogenic Minerals","authors":"L. A. Ivanova, A. E. Baranchikov, Yu. E. Gorshkova, N. A. Verlov, A. A. Kulminskaya, D. V. Lebedev","doi":"10.1134/S2635167625601950","DOIUrl":"10.1134/S2635167625601950","url":null,"abstract":"The role of extracellular DNA in calcium carbonate biomineralization processes is studied using the bacterial culture Bacillus cereus 4B. Different types of DNA, including lysed cell, plasmid, and eukaryotic genomic DNA, are found to significantly affect the kinetics and morphology of calcium carbonate mineral formation. In bacterial systems with varying calcium concentrations, adding cell lysate is shown to accelerate calcium carbonate precipitation and affect the mesoscale structure of aggregates. In an abiogenic system, the addition of plasmid DNA slightly increases the gyration radius of fractal clusters in the crystalline precipitate (from 10.5 to 11.4 nm) and decreases their fractal dimension compared to a system without DNA (from 2.35 to 2.1), while genomic DNA increases it to 2.8. Structural differences in the precipitated minerals suggest that DNA is not only a trigger for biomineralization but also a template for the synthesis of CaCO3 biominerals. This study demonstrates that the molecular characteristics of DNA play a key role in the nucleation, growth, and morphology of mineral structures, opening new perspectives for understanding biomineralization mechanisms.","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 6","pages":"893 - 902"},"PeriodicalIF":0.8,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147335990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adipose Tissue Extracellular Vesicles Influence Interleukin-10 Secretion by Regulatory T Cells In Vitro 脂肪组织细胞外囊泡对体外调节性T细胞分泌白介素-10的影响

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Nanotechnologies in Russia Pub Date : 2026-03-02 DOI: 10.1134/S2635167625600713

M. N. Grunina, K. V. Dracheva, A. D. Izumchenko, I. N. Gaponenko, L. A. Garaeva, M. A. Surtsukova, K. A. Anisimova, E. T. Berulava, S. G. Balandov, D. I. Vasilevsky, S. N. Pchelina, V. V. Miroshnikova

{"title":"Adipose Tissue Extracellular Vesicles Influence Interleukin-10 Secretion by Regulatory T Cells In Vitro","authors":"M. N. Grunina, K. V. Dracheva, A. D. Izumchenko, I. N. Gaponenko, L. A. Garaeva, M. A. Surtsukova, K. A. Anisimova, E. T. Berulava, S. G. Balandov, D. I. Vasilevsky, S. N. Pchelina, V. V. Miroshnikova","doi":"10.1134/S2635167625600713","DOIUrl":"10.1134/S2635167625600713","url":null,"abstract":"Obesity is characterized by chronic inflammation of adipose tissue, which is associated with the development of concomitant diseases. Recent studies indicate that regulatory T cells (Tregs) may play an important role in the pathogenesis of insulin resistance and type 2 diabetes mellitus (T2DM). The aim of the study was to evaluate the effect of extracellular vesicles (EVs) secreted by visceral and subcutaneous adipose tissue (VAT and SAT) of obese patients with/without T2DM on the Treg population, including their secretion of interleukin-10. EVs were obtained after cultivation of VAT and SAT of obese patients with/without T2DM and non-obese individuals. Primary culture of CD4+CD25+ Tregs was obtained by differentiating naive peripheral blood CD4+ T cells of healthy donors. Real-time PCR was used to assess the mRNA level of the genes of interest, and ELISA was used to determine the concentration of interleukin-10 in the culture medium. Simultaneous increase in the IL10 gene mRNA level and decrease in interleukin-10 secretion by Tregs were demonstrated after cultivation in the presence of VAT EVs; in the presence of SAT EVs from obese patients, the level of interleukin-10 secretion was slightly increased. The expression level of IL10 gene in SAT of non-obese individuals was lower compared to VAT, however, in obese patients with T2DM it was increased and comparable to that in VAT. AT EVs can potentially influence the population of Tregs, changing their suppressive activity and secretion of interleukin-10.","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 6","pages":"871 - 880"},"PeriodicalIF":0.8,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147336235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the Production of Innovative Wound Dressings from Bioinert Polymers by Electrospinning 生物惰性聚合物静电纺丝生产新型创面敷料的研究

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Nanotechnologies in Russia Pub Date : 2026-03-02 DOI: 10.1134/S2635167625601755

T. Kh. Tenchurin, A. D. Shepelev, V. G. Mamagulashvili, E. V. Solovyova, K. V. Sidoruk, A. A. Nesmelov, V. G. Bogush, S. N. Chvalun

{"title":"On the Production of Innovative Wound Dressings from Bioinert Polymers by Electrospinning","authors":"T. Kh. Tenchurin, A. D. Shepelev, V. G. Mamagulashvili, E. V. Solovyova, K. V. Sidoruk, A. A. Nesmelov, V. G. Bogush, S. N. Chvalun","doi":"10.1134/S2635167625601755","DOIUrl":"10.1134/S2635167625601755","url":null,"abstract":"One of the promising methods for producing medical devices is electrospinning, which allows for the production of fibrous material with a high specific surface area, porosity, and unique physical and mechanical properties. Microfibrous and nanofibrous materials mimic the structure of a decellularized extracellular matrix, which allows them to be used as cell scaffolds for tissue engineering, surgical membranes, test systems for screening the effects of drugs, and wound dressings. A fibrous material from a copolymer of lactide and caprolactone, cellulose diacetate, and polyvinylpyrrolidone, modified with recombinant spidroin with hybrid proteins containing biologically active peptides, is produced. The assessment of biocompatibility shows that treatment of the fibrous materials with recombinant spidroins and hybrid proteins increased both their adhesive properties for fibroblasts and keratinocytes and the degree of vascularization during subcutaneous implantation. The inclusion of gentamicin into the composition of the fibrous materials made it possible to impart antibacterial properties to them. The obtained results demonstrate the possibility of using the manufactured materials as wound-healing dressings.","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 6","pages":"794 - 801"},"PeriodicalIF":0.8,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147335995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Properties of Nanocrystalline Tin and Zinc Oxide Films during Oxygen Chemisorption 氧化学吸附过程中纳米锡和氧化锌薄膜的性能

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Nanotechnologies in Russia Pub Date : 2026-03-02 DOI: 10.1134/S2635167625601731

A. E. Varfolomeev

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L-Proline-Stabilized Copper Nanoclusters: Synthesis, Optical Properties, and Testing in Bioanalysis by Fluorimetry and Capillary Electrophoresis l -脯氨酸稳定铜纳米团簇：合成、光学性质及荧光和毛细管电泳生物分析测试

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Nanotechnologies in Russia Pub Date : 2026-03-02 DOI: 10.1134/S2635167625601640

A. I. Demenshin, E. A. Kolobova, T. S. Sych, D. V. Danilov, E. V. Solovyeva

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On the Strain Bacillus amyloliquefaciens for Protecting Plants from Phytopathogenic Fungi 解淀粉芽孢杆菌保护植物免受植物病原真菌侵害的研究