Acta Informatica Medica最新文献

{"title":"Water Extract Have Superior Cytotoxic Effect Than Ethanolic Extract of Clinacanthus Nutans Leaves in Breast Cancer Stem Cells.","authors":"Siti Syarifah, Aldy S Rambe, Agung Putra, M Ichwan, Yunita Sari Pane, Adi Muradi Muhar, Alfi Khatib, Delfitri Munir, M Rusda, Mustafa M Amin","doi":"10.5455/aim.2024.32.4-10","DOIUrl":"https://doi.org/10.5455/aim.2024.32.4-10","url":null,"abstract":"<p><strong>Background: </strong>The rapid development of medical technology in managing breast cancer patients still cannot solve the problem of recurrence and resistance. One of the causes of recurrence and molecular resistance is the presence of breast cancer stem cells (BCSCs). Clinacanthus nutans (C.nutans) is a plant found in Medan, North Sumatra, Indonesia. This plant is believed to have anticancer activity in community.</p><p><strong>Objective: </strong>Our study aimed to assess phytochemical of C.nutans leaves, isolate breast cancer stem cells and determine the cytotoxic effects of the ethanolic extract and water extract of C.nutans leaves on breast cancer stem cells at 24, 48, and 72 h of observation.</p><p><strong>Methods: </strong>We underwent the cytotoxic test by using MTT assay and isolated breast cancer stem cells by using MACS and validated them by mammosphere test.</p><p><strong>Results: </strong>We found alkaloids, flavonoids, glycosides and tannins in simplicia and all extracts. BCSCs was valid with the diameter of the mammosphere BCSCs was > 60 μm. The IC50 values of 100%, 60%, 40%, 20% EE, and WE of C.nutans leaves were 227.30; 46.05; 31.12; 98.54, and 16.16 μg/ml respectively in the first 24 hours. In administering WE of C.nutans leaves, BCSCs viability was decreased at 24,48 and 72 hours of observation, namely 69.29±26%; 75.82 ± 21.02% and 38.94±9.34 % (p < 0.0001).</p><p><strong>Conclusion: </strong>The WE of C.nutans leaves had more substantial cytotoxic potential against BCSCs than the EE. The capability of WE C.nutans leaves to suppress BCSC's viability was time-dependent. The anticancer activity were believed originate from alkaloid and flavonoid group.</p>","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"32 1","pages":"4-10"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10997169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140848791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers to the Adoption of Evidence Based Practice in Nursing: a Focus Group Study.","authors":"Maria Pitsillidou, Maria Noula, Zoe Roupa, Antonis Farmakas","doi":"10.5455/aim.2023.31.306-311","DOIUrl":"10.5455/aim.2023.31.306-311","url":null,"abstract":"<p><strong>Background: </strong>Evidence Based Practice is considered a complex process with many factors hindering its implementation. The use of focus groups to detect barriers to its application can provide an in-depth investigation of the phenomenon.</p><p><strong>Objective: </strong>The investigation of nurses' views regarding the obstacles connected to the implementation of Evidence Based Practice.</p><p><strong>Methods: </strong>This is a qualitative study carried out using focus groups and constitutes the continuation of a quantitative study. Deliberate sampling was used to recruit a total of 31 nurses.</p><p><strong>Results: </strong>The main categories that emerged regarding the obstacles in the implementation of Evidence Based Practice in nursing, concerned the lack of logistical support, the difficulty of accessing data, the insufficient knowledge of nurses as well as their attitude, the nature of the work, the decision-making process and the impossibility of safeguarding decisions made.</p><p><strong>Conclusion: </strong>In this study, various factors were identified that affect the application of Evidence Based Practice, in the nursing environment of Cyprus. Identifying these factors can be the basis for discussions and finding ways to resolve the problems that exist by health care managers.</p>","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"31 4","pages":"306-311"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10875937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139911773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Value in Screening Severe Depression of the Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, Beck Depression Inventory Scale, and Zung's Self-Rating Anxiety Scale Among Patients with Recurrent Depression Disorder.","authors":"Vu Son Tung, Nguyen-Van Thong, Nguyen-Thi Phuong Mai, Le-Thi Thao Linh, Dang Cong Son, Tran-Thi Thu Ha, Nguyen-Thi Hoa, Nguyen Thanh Long, Nguyen-Van Tuan","doi":"10.5455/aim.2023.31.249-253","DOIUrl":"10.5455/aim.2023.31.249-253","url":null,"abstract":"<p><strong>Background: </strong>Depression is a widespread and incapacitating mental health disorder that impacts millions of people worldwide, playing a substantial role in the overall global health challenges. Depression has a big impact on a person's quality of life, cognitive and social functioning, risk of suicide, risk of heart disease and other illnesses, as well as death from all causes.</p><p><strong>Objective: </strong>It may be challenging to choose the best tools to screen for severe depression in patients with recurrent depression disorder (PRD) considering the diversity of psychological scales in Vietnam. The aim of this study was to evaluate diagnostic value for detect severe depression of four psychological scales including Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), Beck Depression Inventory Scale (BECK), and Zung's Self-Rating Anxiety Scale (SAS) by genders and age groups among PRD in Vietnam.</p><p><strong>Methods: </strong>This study was conducted at National Institute of Mental Health, Bach Mai Hospital, Vietnam, from 2020 to 2021. There were 109 PRD evaluated with HAM-D, HAM-A, BECK, and SAS by qualified psychiatrists. By analysing Area Under the Curve (AUC) of Receiver Operating Characteristic (ROC) curve, we determined sensitivity, specificity and cut points of four above scales.</p><p><strong>Results: </strong>Among four scales, the BECK scale had the best diagnostic effect with the most optimal sensitivity and specificity (61.64% and 75%, respectively). We proposed the new cut-off of HAM-D, HAM-A, BECK, and SAS for detecting severe depression among PRD were 20, 34, 30, and 45, respectively. By genders, the cut points for the HAM-D, HAM-A, BECK, and SAS in males were 20, 27, 34, and 44, respectively, while those figure in females were 14, 34, 30, and 46, respectively. By age groups, adults had cut values for four above scales of 20, 34, 27, and 45, respectively, whereas those for the elderly were 16, 17, 35, and 44, respectively.</p><p><strong>Conclusion: </strong>We highly recommended that BECK is the most optimal method to screen severe depression in PRD in Vietnam. It is essential to utilize varied cut values of HAM-D, HAM-A, BECK, and SAS for different genders and age groups.</p>","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"31 4","pages":"249-253"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10875955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139911777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Aortic Valve Implantation Two Decades of Evolution - TAVI From Current Perspective.","authors":"Naser Nabil","doi":"10.5455/aim.2023.31.312-321","DOIUrl":"10.5455/aim.2023.31.312-321","url":null,"abstract":"<p><strong>Background: </strong>In the treatment of valvular heart diseases, transcatheter therapies have changed the rules of the game, especially in the case of aortic stenosis and mitral regurgitation. Since the first in man transcatheter aortic valve intervention (TAVI) performed by Dr. Alain Cribier in 2002 in a non-operable aortic stenosis (AS) patient, TAVI has changed the lives of so many patients for whom medical treatment was, up to then, the only option.</p><p><strong>Objective: </strong>This article outlines patient selection and pre-procedure evaluation, current perspectives, recent advances, current and future devices, current guidelines informing the use of TAVI, expanding indications for TAVI, ongoing challenges and the future of TAVI.</p><p><strong>Methods: </strong>The use of these percutaneous techniques has also increased significantly in the past few years with its first application in 2002, transcatheter aortic valve implantation (TAVI) has revolutionized the management of aortic stenosis and has become the standard of care for patients with AS at prohibitively high surgical risks, as well as a preferred treatment for elderly patients with intermediate and high-risk AS.</p><p><strong>Results: </strong>Since the first pioneering procedure was performed 22 years ago, transcatheter aortic valve implantation (TAVI) has evolved into a routine procedure increasingly performed under conscious sedation via transfemoral access. On a global market worth $2 billion per year, over 300 000 patients have received a transcatheter aortic valve, demonstrating its clinical and market impact. TAVI may be used in lower risk, younger, asymptomatic populations with ongoing studies using an expanding portfolio of devices. Also, for patients deemed unsuitable for cardiac surgery, mitral transcatheter therapies represent the treatment of choice. Percutaneous repair techniques have had the most clinical experience to date.</p><p><strong>Conclusion: </strong>During this 20-year period, the increased knowledge on pre-procedural planning, the important technological improvements in transcatheter valves, the increased experience and the numerous studies that have been carried out have permitted an expansion of the indications for TAVI, from inoperable patients to high- and intermediate-risk patients. This article outlines patient selection and pre-procedure evaluation, current perspectives, recent advances, current and future devices, current guidelines informing the use of TAVI, expanding indications for TAVI, ongoing challenges and the future of TAVI.</p>","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"31 4","pages":"312-321"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10875938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139911785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Data Security Resilience in AI-Driven Digital Transformation: Exploring Industry Challenges and Solutions Through ALCOA+ Principles.","authors":"Mikael Ham Sembiring, Fahrul Nizar Novagusda","doi":"10.5455/aim.2024.32.65-70","DOIUrl":"https://doi.org/10.5455/aim.2024.32.65-70","url":null,"abstract":"<p><strong>Background: </strong>The Medicines and Healthcare Products Regulatory Agency (MHRA) defines data integrity as the maintenance of accuracy, consistency, and completeness of data over time. Recently, \"artificial intelligence\" has become prevalent across industries, education, culture,and technology, denoting systems that mimic human intelligence and critical thinking using computers and related technologies.</p><p><strong>Objective: </strong>This article examines the construction of a robust artificial intelligence (AI) system and the incorporation of ALCOA+ principles for data validation, with a specific focus on enhancing data certainty and security.</p><p><strong>Methods: </strong>This study was carried out through a comprehensive review of various Scopus-indexed literature over the past decade. <b>Results and Discussion:</b> AI has been widely applied in Manufacturing System Optimization, involving organizing production systems, including machines, robots, conveyors, and related operations like maintenance and material handling. Moreover, it's used for Process Monitoring, Diagnostics, and Prognostics in medicine, as well as supervision and regulation in industries. Yet, it's not immune to shortcomings, which could result in system biases and jeopardize data security.</p><p><strong>Conclusion: </strong>This article explores the creation of a robust AI system, implementing ALCOA+ for data validation in AI-Driven Digital Transformation to improve data certainty and security in industries. It involves systematically recording AI system activities, ensuring database validity, sustaining data recording practices, regularly updating records, ensuring authenticity and completeness, and facilitating data accessibility for review and audits. As AI integration in education advances, there's a crucial need for oversight to maintain data integrity in these systems.</p>","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"32 1","pages":"65-70"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10997167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140846701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Nerve Sparing in Robotic-Assisted Radical Prostatectomy: A Comparative Investigation of Traditional and Modified Endopelvic Fascia Preservation Techniques.","authors":"Mai Viet Nhat Tan, Nguyen Phuc Cam Hoang, Nguyen Te Kha, Do Vu Phuong, Nguyen Thanh Tuan, Trang Vo Anh Vinh, Nguyen Vuong Bao Anh, Nguyen Truong Vien","doi":"10.5455/aim.2024.32.76-81","DOIUrl":"https://doi.org/10.5455/aim.2024.32.76-81","url":null,"abstract":"<p><strong>Background: </strong>Prostate cancer (PCa) is the second most common cancer and the sixth leading cause of cancer-related mortality in men. In 2000, Abbou performed the first robot-assisted radical prostatectomy, and radical prostatectomy has developed rapidly. Robot-assisted radical prostatectomy (RARP) is a valuable therapeutic option for the management of localized Pca.</p><p><strong>Objective: </strong>To present the functional outcome of robot-assisted laparoscopic radical prostatectomy using traditional and modified endopelvic fascia preservation methods in a single center in Vietnam.</p><p><strong>Methods: </strong>We prospectively analyzed a series of 65 patients diagnosed with prostate cancer from 2020 to 2023. All of those were operated by DaVinci Si system robot-assisted laparoscopic prostatectomy. Twenties patients were applied with a modified nerve-sparing technique, intrafascial dissection, and lateral prostatic fascia preservation, leaving the lateral tissue, including the neurovascular bundle, untouched and covered. We used the traditional approach, intrafascial nerve-sparing with open endopelvic fascia and lateral prostatic fascia in 45 cases. Patients were followed up to 12 months to assess the continence and erectile function by using IIEF-5 and EPIC questionnaires.</p><p><strong>Results: </strong>The study sample included 65 cases; the mean patient age was 64.21 ± 6.68, erection rate after surgery at six months in bilateral NS was 36.58% (15/41) in the traditional group, and 68.42% (13/19) in the modified group (p=0.028). The patient did not recover erectile ability in the group of elderly patients (>65 years old) and unilateral nerve-sparing group. The continence rate six months after surgery was 86.66 % in the conventional group and 85% in the modified group, with no significant difference between the two groups. In the potency group, the IIEF-5 score was 13 ± 4.9, and the EPIC-26 score was 62.20 ± 10.04. Erectile ability in the modified group was better than the traditional group at six months after surgery.</p><p><strong>Conclusion: </strong>Our results showed better potency recovery in the modified group. These results should be tested in future research with randomized studies.</p>","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"32 1","pages":"76-81"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10997170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140848866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric Study of Lumbar Spinal Canal Dimensions in Bosnia and Herzegovina Population.","authors":"Midhat Cizmic,&nbsp;Emir Hadziosmanovic,&nbsp;Rusmir Baljic,&nbsp;Adi Ahmetspahic,&nbsp;Zulejha Merhemic","doi":"10.5455/aim.2023.31.200-205","DOIUrl":"https://doi.org/10.5455/aim.2023.31.200-205","url":null,"abstract":"<p><strong>Background: </strong>The lumbar spinal canal consists of 5 interconnected lumbar vertebrae through which the final part of the spinal cord passes and the lumbar and sacral spinal nerves that form the cauda equina. The lumbar canal stenosis can directly affect neurological symptoms and pain in the lumbar region and lower extremities. Due to the frequency of such symptoms, lumbar stenosis has been the subject of research around the world.</p><p><strong>Objective: </strong>The objective of this study was to measure, analyze and compare the mediosagital and interpeduncular diameters of the lumbar spinal canal in the population of Bosnia and Herzegovina to other populations around the world.</p><p><strong>Methods: </strong>We conducted a retrospective descriptive study on patients (n=200) who underwent Multi-slice computer tomography (MSCT) performed on a 40-slice CT scanner (Siemens Somatom Definition AS) for lumbar pain between January 1, 2013 and December 31, 2014. Age, gender, midsagittal (MSG) and interpeduncular (IP) diameters of the lumbar spine were recorded for each patient.</p><p><strong>Results: </strong>Results of our study show that the largest MSG diameter is at L1 level for both sexes, with an average length of 19,06mm, and the smallest at L3 level, with an average length of 16,66mm. Our study shows that the MSG diameter is significantly larger in females than males on all levels from L1 to L5. In both sexes, MSG diameter shows the form of an hourglass with narrowing at L3 level. IPD is largest at L5 level for both sexes, with an average length of 31,94mm, and the smallest average length at L1 level, at 24,78mm. IPD diameter is significantly larger in males than females on all levels from L1 to L5. IPD shows a tendency of growth from L1 to L5 in both sexes.</p><p><strong>Conclusion: </strong>There were significant differences in the dimensions of the lumbar spine canal between female and male patients. We found significant difference in MSG and IP diameters measurements between Bosnian and Herzegovinian population compared to other populations. The dimensions of the lumbar canal provide a baseline of normative data for the evaluation of patients presenting with lower back pain and lumbar canal stenosis in study population.</p>","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"31 3","pages":"200-205"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/95/d4/AIM-31-200.PMC10540747.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41127311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psoriasis Area and Severity Index (PASI) Objectivisation by Flow Cytometry Analysis of Major Lymphocytes Subsets.","authors":"Lamija Zecevic-Pasic,&nbsp;Nejra Dzananovic,&nbsp;Refet Gojak,&nbsp;Suzana Tihic-Kapidzic,&nbsp;Berina Hasanefendic,&nbsp;Ermin Begovic,&nbsp;Amir Fazlagic","doi":"10.5455/aim.2023.31.206-210","DOIUrl":"https://doi.org/10.5455/aim.2023.31.206-210","url":null,"abstract":"<p><strong>Background: </strong>Psoriasis as an immune-mediated inflammatory skin disease. The basis of the pathogenesis of psoriasis is the dysregulation of immune cell function in genetically predisposed individuals. The characteristic dysfunction of the immune system in patients with psoriasis is manifested as a variation in the cellular phenotypic profile in accordance with the disease status.</p><p><strong>Objective: </strong>The aim of this study was to evaluate the immunophenotypic profile of lymphocytes obtained by flow cytometry as an auxiliary diagnostic tool in the objectivization of the PASI score.</p><p><strong>Methods: </strong>The study group included 40 patients with psoriasis, hospitalized and treated at Dermatology Clinic of Clinical center University of Sarajevo and 30 healthy individuals as controls. After venepunction, the blood samples for determining the immune profile were prepared following standard laboratory procedures using conjugated monoclonal antibodies and BD FACSCanto II flow cytometer. T-lymphocytes (CD3, CD4, CD8), B lymphocytes (CD19), Natural killer cells (NK), and activatet T-cells (CD3HLA) were determined for all patients. Based on the PASI score, the severity and area of the disease was assessed for all psoriasis patients by dermatology specialist.</p><p><strong>Results: </strong>Our data shows no significant difference in any of the lymphocyte subpopulations between psoriasis patients and healthy controls, except CD3HLA. CD3HLA has higher values in patients with psoriasis, p=0.015. Of all the parameters, only NK cells were significantly correlated to the PASI score (rho -0.279; p=0.048). ROC curve analysis revealed a statistically significant difference for the proportion of CD3 lymphocytes (AUC 0.799; p=0.004), CD8 lymphocytes (AUC 0.733; p= 0.023), NK cells (AUC 0.722; p=0.008) and CD3HLA activated T lymphocytes (AUC 0.347; p=0.034).</p><p><strong>Conclusion: </strong>Profile of major lymphocyte subsets in patients with psoriasis is similar to that of healthy controls. The values of CD3, CD8, NK, CD3HLA were defined as biomarkers capable of distinguishing psoriasis according to the severity of the disease. Immunophenotyping of peripheral blood lymphocytes can play an important role as an auxiliary diagnostic method in differentiating the clinical stages of psoriasis and objectifying the PASI score.</p>","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"31 3","pages":"206-210"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/85/2f/AIM-31-206.PMC10540746.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41110356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single Immediate Implant Placement with Provisional Crown in the Esthetic Zone with 6 Years Follow-Up.","authors":"Elie Maalouf,&nbsp;Eliano Nakhoul,&nbsp;Fady Abillamaa,&nbsp;Georges Aoun","doi":"10.5455/aim.2023.31.226-230","DOIUrl":"https://doi.org/10.5455/aim.2023.31.226-230","url":null,"abstract":"<p><strong>Background: </strong>Immediate implant placement (IIP) has become an attractive treatment for many patients. It reduces time and the number of appointments and protects soft and hard tissue, which, in many circumstances, leads to a better esthetic outcome. IIP with provisionalization (IIPP) may contribute to a more promising result due to the guidance of soft tissue and the preservation of the hard tissue. Indications for IIPP are quite strict, and cone beam computed tomography (CBCT) is a must for case selection.</p><p><strong>Objective: </strong>This case report will demonstrate how IIP with immediate provisionalization can result in a high esthetic outcome and no discomfort for the patient.</p><p><strong>Case presentation: </strong>A 50-year-old female presented for implant placement following the extraction of a superior central incisor due to a vertical fracture. IIPP has been used.</p><p><strong>Conclusion: </strong>IIPP can accomplish a stable esthetic result in the case of ideal three-dimensional implant positioning, a well-polished provisional restoration with an S-shaped buccal emergence profile, and by respecting the mesial and distal embrasure spaces for papilla maturity.</p>","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"31 3","pages":"226-230"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/06/AIM-31-226.PMC10540750.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41100656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in Collecting and Reporting Health Statistics in Kosovo.","authors":"Naser Rugova, Erza Voca Mulaj, Doncho Donev","doi":"10.5455/aim.2024.32.61-64","DOIUrl":"https://doi.org/10.5455/aim.2024.32.61-64","url":null,"abstract":"<p><strong>Background: </strong>Statistical data play a crucial role in research, planning and decision making in the health system, especially in the formulation and implementation of health policies. Health policy, adequate health legislation and sustainable financing of the health system remain serious challenges for countries in transition and especially for the Republic of Kosovo.</p><p><strong>Objective: </strong>To analyze the challenges of collection, accuracy and accurate reporting and the impact of the accuracy of these health statistics on the creation of appropriate public health policies in Kosovo.</p><p><strong>Methods: </strong>This research is mainly based on a combination of qualitative, quantitative, deductive, analytical and comparative methods conducted by health workers at all three levels of the health organization and IT experts who were actively involved in some of the important components of our research.</p><p><strong>Results: </strong>It is interesting to note that respondents gave typical scores for the security and confidentiality of medical data and statistics during the cycle of their collection and processing, with one score being 3 and the other 5, and 50% of respondents gave a score of 5 for the successful fulfilment of the mission and tasks established by the Law on the rational use of medical data and statistics to support public health policy.</p><p><strong>Conclusion: </strong>The research and findings provide sufficient evidence that Kosovar health data and statistics system suffers from serious deficiencies ranging from the legal framework, organizational structure, functional organization, segregation of duties and responsibilities, to a pronounced lack of human resources, professional profiles in the health statistics service and the necessary technology to perform the basic tasks in a timely and high quality manner.</p>","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"32 1","pages":"61-64"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10997164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140846884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}