I. Masic, A. Kurjak, S. Janković, O. Sinanović, D. Donev, B. Djulbegovic, Kenan Arnautovic, M. Zildžić, E. Zerem, S. Kunosić, Sylwia B. Ufnalska
{"title":"On the Occasion of the 12th “Days of AMNuBiH 2021” and “SWEP 2021” Conferences, Sarajevo, Bosnia and Herzegovina","authors":"I. Masic, A. Kurjak, S. Janković, O. Sinanović, D. Donev, B. Djulbegovic, Kenan Arnautovic, M. Zildžić, E. Zerem, S. Kunosić, Sylwia B. Ufnalska","doi":"10.5455/aim.2021.29.295-310","DOIUrl":"https://doi.org/10.5455/aim.2021.29.295-310","url":null,"abstract":"It is very well known that science is world activity and that there is no good and bad work in the field of scientific research. Nowadays scientific productivity of the individuals, learned societies on regional or state level are measurable parameters. In most of the systems it does include the number of original scientifi papers, quality of journals measured by impact factor and scientific citation index (1-4). There are also additional measurable parameters but for the purpose of this meeting we will avoid discussion about them. New field of scientometrics using the help of impartial and ruthless machines (computers) do help very significantly in evaluation of scientific productivity anywhere in the world. Unfortunately, there are many misused conclusions and interpretation on the data offered by computers. It is clear that some vital important changes are urgently needed. Today’s conference should use rare opportunity having together experts in the field to discuss the problems visible now. This author intends to discuss facts and doubts in writing review articles and chapters in the book (5). Some important flexibility in citation, in particular self citation, should be analyzed. An illustrative examples from author’s own experience will be shown and discussed at the meeting.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"29 1","pages":"295 - 306"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49121209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Most Influential Scientists in the Development of Medical Informatics (30): Hans Peterson (1928-2021)","authors":"I. Masic","doi":"10.5455/aim.2020.28.130-134","DOIUrl":"https://doi.org/10.5455/aim.2020.28.130-134","url":null,"abstract":"Hans Peterson, MD, PhD, FEFMI, FACMI, FIMIA, FIAHSI (1928-2021), became a certified physician in Sweden in 1958 and was awarded a doctorate in Medicine in 1967 (1-4). He was an ophthalmology fellow at the Karolinska Institute, Stockholm University, and was appointed to faculty positions in Ophthalmology and Medical Informatics at the Karolinska in the late 1970’s.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"29 1","pages":"134 - 135"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43430499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Most Influential Scientists in the Development of Medical Informatics (26): Barry Barber (1933-2019)","authors":"I. Masic","doi":"10.5455/aim.2020.28.145-145","DOIUrl":"https://doi.org/10.5455/aim.2020.28.145-145","url":null,"abstract":"","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"28 1","pages":"144 - 145"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44600827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alma Biscevic, Maja Bohac, M. Pjano, Senad Grišević, Sudi Patel, Ajla Pidro
{"title":"Treatment of High Astigmatism with WaveLight Allegretto Eye-Q Excimer Laser Platform","authors":"Alma Biscevic, Maja Bohac, M. Pjano, Senad Grišević, Sudi Patel, Ajla Pidro","doi":"10.5455/aim.2019.27.177-180","DOIUrl":"https://doi.org/10.5455/aim.2019.27.177-180","url":null,"abstract":"Introduction: The WaveLight Allegretto Eye-Q is a flying-spot excimer laser, with a pulse repetition rate of 400Hz, with two galvanometric scanners for positioning laser pulses. The system has an infrared high speed camera operating at 400Hz to track the patient’s eye movements that either compensates for changes in eye position or interrupts the treatment if the eye moves outside a preset predetermined range. Aim: The purpose of this study was to investigate WaveLight Allegretto Eye-Q 400Hz laser delivery platform aimed to correct astigmatism by subjecting the pre and postoperative astigmatic values to vector analysis. Methods: Patients were divided into two groups, depending on the type of astigmatism. Astigmatism was between 2 and 7 diopters (D). A total of 188 eyes (110 patients), 127 eyes (71 patients) with myopic astigmatism and 61 eyes (39 patients) with mixed astigmatism underwent unremarkable LASIK correction on WaveLight Allegretto Eye-Q 400Hz. The preoperative and postoperative sphere, negative cylinder [C] and axis (ø) of manifest refractions were subjected to vector analysis by calculations of the standard J0 (cos [4π(ø-90)/360]xC/2) and J45 (sin[4π(ø-90)/ 360]xC/2). Results: Reporting the key results, we found that J0 significantly reduced after LASIK (p<0.001) but not J45. There was no significant association between individual pairs of pre and postoperative J0 &J45 values. Conclusion: WaveLight Allegretto 400Hz showed excellent results for treating patients with high astigmatism, regardless whether it is mixed or myopic astigmatism. The J45 did not reduce significantly possibly because of the low number of eyes with oblique astigmatism. There was no genuine difference postoperatively between groups treated on WaveLight Allegretto platform according to the vector analyses.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"177 - 180"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44782848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Noise Effect on Blood Pressure and Heart Rate - Regression Analysis in Service of Prediction","authors":"Fikret Veljović, Senad Burak, E. Begić, I. Masic","doi":"10.5455/aim.2019.27.162-166","DOIUrl":"https://doi.org/10.5455/aim.2019.27.162-166","url":null,"abstract":"Introduction: Investigations have shown that noise is one of the etiologic factors that leads to a risk of cardiovascular incidence. Aim: To present effect of noise on arterial tension and heart rate of workers who work on machine press during period of three-years. Methods: The study had a prospective character and included 30 subjects (n = 30) who were monitored over a three-year period (36 months). The respondents worked at the factory “Cimos” on machine press (Zenica, Bosnia and Herzegovina). Ten machine presses were monitored, and three workers worked on each press. Approximately every worker was affected by a wide range of noise between 65 and 110 dB in the workplace (via isohypse). MATLAB (version 9.4, MathWorks, Natick, Massachusetts, United States of America (USA)) software was used to estimate the possible damage caused by noise in factories that produce noise in their work. Results: During the three-year period, arterial tension in the subjects increased, and at the end of the observed period, they were considered as patients with a diagnosis of arterial hypertension grade I. The tension depends on the strength of the produced noise, and the values also depend on position of the respondent on the machine press. Conclusion: Noise prevention has become a problem of modern medicine. The result of our work allows estimation of arterial hypertension in specified time in case of exposure to a certain strength of noise. Prevention of noise, daytime noise prevention as well as better equipment for work and preventive equipment are imposed as imperative in such or similar conditions, with the need of development of national strategies for this issue in countries where they are not present.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"162 - 166"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43126839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Congenital Hydronephrosis with Static and Dynamic Magnetic Resonance Urography in Comparation to Dynamic Renal Scintigraphy","authors":"Amra Džananović, A. Begić, D. Pokrajac","doi":"10.5455/aim.2019.27.181-185","DOIUrl":"https://doi.org/10.5455/aim.2019.27.181-185","url":null,"abstract":"Introduction: Congenital hydronephrosis (CH) is a condition with dilated renal pelvis with or without dilation of renal calyces. Aim: To examine the role of magnetic resonance urography in the detection of congenital hydronephrosis in comparison to dynamic renal scintigraphy (DRS). Patients and methods: Resarch included 58 (n=58) patients with diagnosis of congenital unilateral or bilateral dilatation of kidney duct system. Each patient had a one-time or multiple hospitalization at the Nephrology Department of the Pediatric Clinic, with performed: ultrasound which confirmed CH, voiding cystourethrography / voiding urosonography was confirmed based on which the vesicoureteral reflux (VUR) was established / excluded, dynamic renal scintigraphy and magnetic urography (analysis was made by CHOP-fMRU software) on the basis of which the uterine anatomy and the relative renal function were evaluated. Results: Male patients were represented in 40 cases (69%). The average age was 4.4 ± 4.3 years with the youngest patient at the age of 2 months, and the oldest was 17 years old. According to diagnostic entities, the most common diagnosis was ureteropelvic junction (UPJ) obstruction in over half of cases (30 or 51.7%), followed by subjects with ureterovesical junction (UVJ) obstruction (11 or 19%), VUR was recorded in 9 (15.5%) cases, and pyelon fissus in 7 (12.1%), and one case (1.7%) was recorded with bilateral megaureter. Comparison of the value of the renal function obtained with DRS and CHOP-fMRU methods shows that there were no statistically significant differences between two methods. In the case of right kidney, the mean DRS value was 53.4 ± 18.4% (range 13-100%), while CHOP-fMRU was 51.8 ± 22.4 (range 0-96.7%). In the case of left kidney, the average value according to the DRS method was 46.9 ± 18.9% (range 0-87%) and according to CHOP-fMRU 47.6 ± 21.5% (range 8.3-100%). The correlation coefficients of both right and left kidneys show a highly statistically significant correlation between these two methods. Conclusion: Magnetic resonance urography in the pediatric population in CH based on results should be an integral part of the management of these patients, especially in congenital obstructive uropathy, in complex and associated congenital anomalies, as it provides morphological and functional data on the state of the kidneys and urinary tract.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"181 - 185"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44443724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Medical Information Extraction Model for User-generated Content","authors":"Fahad Kamal Alsheref","doi":"10.5455/aim.2019.27.192-198","DOIUrl":"https://doi.org/10.5455/aim.2019.27.192-198","url":null,"abstract":"Introduction: The number of social network users is on the rise, and the size of the user-generated contents is increasing as well. Analyzing the generated contents can lead to the attainment of a vast amount of information, such as users’ feelings on specific products or events, or personal information about life events. Aim: The aim of this paper is to describe an model for detecting medical information present in generated contents, such as posts or comments. Results: The proposed model is based on the Unified Medical Language System (UMLS) and is tested on a dataset collected from Twitter and Facebook. The extracted information can be used to aid in the early detection of diseases or to supply commercial benefits to medical companies. Experimental results demonstrate that the proposed model achieves 94.6% accuracy and 87% precision. Conclusion: In this study, we attempted to extract clinical information present in UGC. Using the proposed model should involve a reliable dataset that contains most clinical expressions; the UMLS was a suitable dataset for our model.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"192 - 198"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42614580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dewi Ratih Tirto Sari, J. Cairns, A. Safitri, F. Fatchiyah
{"title":"Virtual Prediction of the Delphinidin-3-O-glucoside and Peonidin-3-O-glucoside as Anti-inflammatory of TNF-α Signaling","authors":"Dewi Ratih Tirto Sari, J. Cairns, A. Safitri, F. Fatchiyah","doi":"10.5455/aim.2019.27.152-157","DOIUrl":"https://doi.org/10.5455/aim.2019.27.152-157","url":null,"abstract":"Introduction: Anthocyanin is the bioactive compound in black rice, which promotes some health benefits for human body. Present study revealed that black rice anthocyanins improve the biomarker of the metabolic syndrome, such as tumor necrosis factor alpha (TNF-α). However, the mechanism of anthocyanin in preventing metabolic syndrome has not been elucidated. Aim: This study was performed to identify the interaction of six types of black rice anthocyanin towards TNF-α protein and TNF-α receptor through in silico studies, to assess the molecular properties and bioactivity of black rice anthocyanin. Methods: We retrieved the black rice anthocyanin compounds from the PubChem database and the proteins (TNF-α protein and TNF-α receptor) from Protein Data Bank (PDB) database. Protein and ligands were docked using Hex 8.0 software and visualized by Discovery Studio 4.1 program. Results: This study found the possibility that black rice anthocyanins interacted with TNF-α have no influence into TNF-α and TNF-α receptor interaction. The binding of delphinidin-3-O-glucoside & peonidin-3-O-glucoside to TNF-α receptor inhibited the TNF-α and TNF-α receptor signaling. The black rice anthocyanins had low activity as a drug. Interestingly, black rice anthocyanins had a potency as an antioxidant due to the hydrogen donor or acceptor in their structure, as protein kinase inhibitor, nuclear receptor ligand, and enzyme kinase inhibitor. Conclusion: This study suggests that delphinidin-3-O-glucoside and peonidin-3-O-glucoside might have function as anti-inflammatory factor related with TNF-α signaling.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"152 - 157"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42768421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}