Microchimica Acta最新文献

{"title":"On exploring the potential of machine learning assisted nanoparticles enhanced laser induced breakdown spectroscopy as an initial screening tool for early breast cancer detection","authors":"Shahwal Sabir,&nbsp;Ayesha Israr,&nbsp;Muhammad Faheem,&nbsp;Ghulam Rasool Sani,&nbsp;Aqsa Khalid,&nbsp;Sajid Bashir,&nbsp;Tania Jabbar,&nbsp;Yasir Jamil","doi":"10.1007/s00604-025-07517-y","DOIUrl":"10.1007/s00604-025-07517-y","url":null,"abstract":"<div><p>Early detection of cancer in low income countries is still a major health problem. This study discovers a novel diagnostic technique based on Nanoparticle-Enhanced Laser-Induced Breakdown Spectroscopy (NE-LIBS), which combines machine learning, nanotechnology, and laser-based elemental analysis as a potential early screening tool reported for the first time to our knowledge. We have explored that the incorporation of silver and copper oxide nanoparticles significantly enhances the intensity of emission signals of laser induced blood plasma, particularly of metallic biomarkers sodium and calcium, which have previously been known to reflect cancer-related metabolic changes. The use of advanced machine learning models to analyze these improved spectral features enables the accurate classification of cancerous and non-cancerous samples with an accuracy of nearly 95%. In low-income countries where conventional methods are still unavailable, machine learning assisted NE-LIBS has the potential to develop into a future platform that would enable scalable, reasonably priced initial clinical cancer screening when combined with machine learning.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 10","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145037500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-signal colorimetric sensor based on Fe,Ce-CDs for ultra-sensitive detection of nitrite in tobacco","authors":"Dongling Meng,&nbsp;Zhiyan Chen,&nbsp;Zhibin Chen,&nbsp;Junrao Cen,&nbsp;Jitao Li,&nbsp;Yaling Yang","doi":"10.1007/s00604-025-07500-7","DOIUrl":"10.1007/s00604-025-07500-7","url":null,"abstract":"<div><p>Iron-cerium co-doped carbon dots (Fe,Ce-CDs) were synthesized by one-step hydrothermal method using tartaric acid and L-tryptophan as ligands. Fe,Ce-CDs shows excellent peroxidase-like (POD) activity and nitrite (NO₂⁻) can promote the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) to its blue oxidation product (oxTMB) due to the formation of ∙NO₂ free radical. NO₂⁻ further react with oxTMB to form a yellow color via diazotization resulting in the absorbance Change at 450 nm. By Fe,Ce-CDs + NO₂⁻ + TMB + H₂O₂ and oxTMB + NO₂⁻ systems, a dual-signal colorimetric nanosensor for NO₂⁻ detection is developed with lower detection limits (LODs) of 0.272 μg/L and 0.019 mg/L, respectively. The proposed methods were applied to the detection of NO₂⁻ in tobacco samples with good recovery from 91.20 to 110.61%, achieving similar results and indicating their high accuracy and feasibility.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 10","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid ZrO₂@CNTs nanocomposite electrodes for ultra-sensitive glucose detection via electrochemical biosensing","authors":"Guang Shi,&nbsp;Liang Cheng,&nbsp;Shangdong Chen","doi":"10.1007/s00604-025-07479-1","DOIUrl":"10.1007/s00604-025-07479-1","url":null,"abstract":"<div><p>A sensitive electrochemical glucose biosensor using ZrO₂@CNTs nanocomposite was developed for real-time metabolism monitoring for athletes. The nanocomposite was prepared by a simple ultrasound-assisted technique, and the glucose oxidase (GOx) was covalently immobilized to improve the biorecognition ability. CNTs treated with acid served as a highly conductive framework, and ZrO₂ nanoparticles can provide structural stability and catalytic performance, thus showing synergistic enhancement of electron transfer kinetics and enzyme loading capacity. A SEM, XRD, FTIR, and XPS comprehensive characterization indicated the successful integration of the nanostructures and attachment of the enzyme. The electrochemical measurements provide an exceptionally wide linear range (20 to 10,040 µM) and a very low detection Limit of 0.17 µM, indicating high sensitivity, selectivity, and excellent stability in the operation of the device. The high specificity was further validated in real samples of human serum and almond juice and agreed well with high-performance liquid chromatography (HPLC) data (recoveries &gt; 98.9%). The GOx/ZrO₂@CNTs-based biosensors provide an encouraging platform for such applications as wearable, real-time monitoring of glucose in athletes and other high-performance sports.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 10","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145021592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of an Ag+-functionalized structural color hydrogel sensor for colorimetric detection of glutathione","authors":"Qianqian Feng,&nbsp;Jiang Zhou,&nbsp;Lingfeng Wang,&nbsp;Xiaojiao Gong,&nbsp;Qiang Xi,&nbsp;Shengyuan Yang,&nbsp;Wenfang Du,&nbsp;Fubing Xiao","doi":"10.1007/s00604-025-07442-0","DOIUrl":"10.1007/s00604-025-07442-0","url":null,"abstract":"<div><p>An Ag⁺-functionalized structural color hydrogel (Ag⁺-SCH) sensor is constructed for colorimetric detection of glutathione (GSH). The hydrogel is prepared by using the coordination of Ag⁺ and 1-vinylimidazole (1-VI) as cross-linking network. GSH acts as a competitive ligand to break the coordination between Ag⁺ and 1-VI, leading to the expansion and structural color change of the hydrogel. Quantification was achieved by measuring particle spacing changes, yielding a dynamic range of 0.1–200 μM with a limit of detection (LOD) of 0.04 μM. Alternatively, smartphone-based hue analysis enables sensitive GSH detection with a LOD of 0.79 μM. The sensor has proven to show high selectivity, excellent reusability, and long-term stability. In human serum tests, the Ag⁺-SCH performed comparably to commercial kits, while offering significantly lower cost. This portable, low-cost platform meets practical needs for GSH monitoring in diverse settings.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 10","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145021593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel fluorescent aptasensor using magnetic silica nanospheres and Ag@MOF nanocomposites for extraction and detection of Salmonella Typhimurium in eggs","authors":"Narges Kiani-Salmi,&nbsp;Matthew D. Moore,&nbsp;Zahra Ghasempour,&nbsp;Ali Ehsani,&nbsp;Jafar Soleymani","doi":"10.1007/s00604-025-07492-4","DOIUrl":"10.1007/s00604-025-07492-4","url":null,"abstract":"<div><p><i>Salmonella</i> Typhimurium (<i>S.</i> Typhimurium) is one of the most common food-borne diseases, highlighted as the top food-borne bacterial pathogen in the world with a low infectious dose (1 CFU) and high mortality rate. It is commonly associated with numerous foods such as dairy products, protein sources (multiple types of meat, poultry, and eggs), and bakery products. Therefore, an accurate and rapid detection method for this bacterium is always needed. This study used a fluorescent platform based on extraction and detection of the <i>S.</i> Typhimurium in eggs. Specifically, <i>S.</i> Typhimurium was isolated using aptamer-functionalized magnetic nanoparticles and then detected using a fluorescent method by aptamer-functionalized metal–organic frameworks. Under optimal conditions, this study achieved a linear detection range of 7.5 to 7.5 × 10⁶ CFU/mL, a detection limit of 4.61 CFU/mL, and a total detection time of 90 min. The recovery range for egg samples was 97.0–101.0%, proposing high accuracy of the developed probe in real samples. Also, the specificity study results confirmed excellent selectivity of the probe in the presence of non-target bacteria, arising from the stable interactions between the <i>S.</i> Typhimurium and aptamer-functionalized probes. This platform serves as an effective in situ probe for fast and reliable control of eggs and may also be validated for other food samples.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 10","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the efficiency of cyclodextrin polymers as sustainable sampling material for catching palytoxin-like compounds in seawater","authors":"Antonella Miglione,&nbsp;Chiara Melchiorre,&nbsp;Samuela Capellacci,&nbsp;Luciana Tartaglione,&nbsp;Michela Varra,&nbsp;Alex Fragoso,&nbsp;Silvia Casabianca,&nbsp;Mabel Torréns,&nbsp;Jorge Diogène,&nbsp;Antonella Penna,&nbsp;Carmela Dell’Aversano,&nbsp;Mònica Campàs","doi":"10.1007/s00604-025-07507-0","DOIUrl":"10.1007/s00604-025-07507-0","url":null,"abstract":"<div><p>Palytoxin-like compounds, including ovatoxins, are potent emerging toxins responsible for human respiratory poisonings following inhalation of contaminated marine aerosols. Periodic massive proliferations of the ovatoxin-producing organism (<i>Ostreopsis</i> cf. <i>ovata</i>) worldwide, particularly in the Mediterranean, have caused severe toxic outbreaks, drawing the attention of health authorities. At present, an efficient and sustainable sampling system for monitoring ovatoxins in seawater remains unavailable. Herein, different cyclodextrin (CD) polymers were investigated as a green and effective alternative to conventional and low-performing resins to detect ovatoxins in seawater. Spiking experiments using different concentrations of palytoxin or ovatoxins (namely 200 and 3.3 ng PLTX/mL or 200 ng OVTX-a/mL) were conducted and LC-HRMS was used to evaluate the suitability of CD polymers in capturing palytoxin-like compounds. Several conditions were tested for extracting polymer materials, including different extraction times (1.5 to 4 h), various solvent mixtures (acidic or alkaline), and organic modifiers (methanol or acetonitrile) at different ratios. Among the tested polymers, γ-CD-hexamethylene diisocyanate (HDI) resulted to be the most promising one, providing ovatoxin recoveries in the range 82–108% at a spiking level of 200 ng OVTX-a per mL. The best extracting condition was alkaline pH methanol:water 8:2 mixture, which showed the best palytoxin recovery in both high and low concentration spiking experiments. Finally, a time-dependent increase in the amount of ovatoxins captured by γ-CD-HDI disks deployed in <i>O</i>. cf. <i>ovata</i> cultures was observed. These findings provide valuable insights on the efficiency of passive sampling using CD polymers for capturing ovatoxins during <i>O</i>. cf. <i>ovata</i> bloom events.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 10","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00604-025-07507-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145028269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MXene/PANI/SnO2 electrochemical sensor for the determination of 4-aminophenol","authors":"Jing Chen,&nbsp;Wenli Xue,&nbsp;Yaqin Shi,&nbsp;Wenjing Liu,&nbsp;Rongfang Ma","doi":"10.1007/s00604-025-07467-5","DOIUrl":"10.1007/s00604-025-07467-5","url":null,"abstract":"<div><p> An electrochemical sensor based on MXene/PANI/SnO₂ nanomaterials was developed for the detection of 4-aminophenol (4-AP). In situ oxidative growth of PANI on the MXene surface effectively hindered the stacking of the lamellae and increased the specific surface area of the composites. Further complexation of tin dioxide with swelling properties of the structure provided adsorption and catalytic sites for 4-AP. The prepared electrochemical sensor displayed good Linearity in the concentration range 0.50 ~ 115.38 µM and low detection limit (LOD = 0.19 µM). The sensor also had good reproducibility and stability. The MXene/PANI/SnO₂/GCE sensor was applied to the determination of tablets and Yellow River water, and expressed high recoveries and low relative standard deviations.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 10","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyester-coated stainless-steel sheets using silica gel microparticles as surface pre-modifiers: a novel approach to determine selective serotonin reuptake inhibitors in saliva samples by direct infusion tandem mass spectrometry","authors":"Ana M. Pedraza-Soto,&nbsp;Rafael Lucena,&nbsp;Soledad Cárdenas","doi":"10.1007/s00604-025-07521-2","DOIUrl":"10.1007/s00604-025-07521-2","url":null,"abstract":"<div><p>Stainless-steel substrates have grown in importance in the development of planar sorptive phases. However, the reduced wettability of polished sheets makes difficult their functionalization. This limitation can be solved by using amorphous silica gel microparticles as superficial guides. These particles increase both the wettability and the surface area of the final sorptive phases, which has a key influence on the extraction kinetics. In this article, double-sided thermal-resistant adhesive tape was used as the binder to pre-immobilize the silica particles over the stainless-steel surface, thus avoiding aggressive etching procedures. A linear polyester (synthesized by conventional free melt polycondensation from 1,4-butanediol and phenylsuccinic acid) was deposited onto the particulate area by the drop-casting technique. The resulting polyester-silica gel sheets (PSG-sheets) have been evaluated for the extraction of four selective serotonin reuptake inhibitors (SSRI) (fluoxetine, paroxetine, sertraline, and venlafaxine) in saliva samples, followed by direct infusion mass spectrometry analysis. The method allows the determination of the target compounds at the low µg·L⁻¹ range, and it was successfully applied to analyze a saliva sample from a patient under paroxetine treatment. The method also fulfills the typical validation criteria in terms of precision (intrer-day precision better than 16.5% at the limit of quantification) and accuracy (relative recoveries in the interval 87–123% at the limit of quantification), both parameters having been evaluated at four concentration levels.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 10","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00604-025-07521-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced sensitivity detection via orientational labelling of SPA-functionalized magnetic nanoparticles in lateral-flow immunoassays","authors":"Penghua Zhao,&nbsp;Yaping Li,&nbsp;Qing Feng,&nbsp;Xueping Huo,&nbsp;Jingying Sun,&nbsp;Zifan Lu,&nbsp;Zhangjun Song","doi":"10.1007/s00604-025-07392-7","DOIUrl":"10.1007/s00604-025-07392-7","url":null,"abstract":"<div><p><i>Mycoplasma pneumonia</i>, a primary aetiological agent of atypical pneumonia, necessitates the implementation of rapid point-of-care diagnostics. Lateral flow immunoassays (LFIAs) hold promise for point-of-care testing (POCT), yet their sensitivity levels are frequently constrained by probe affinity and matrix interference. We introduce an orientational labelling strategy that employs magnetic nanoparticles (MNPs) functionalized with staphylococcal protein A (SPA) to simultaneously enhance antibody orientation and facilitate magnetic enrichment. The SPA–MNPs were synthesized via aggregation‒precipitation crosslinking, utilizing the Fc-binding specificity of SPA to enable oriented antibody conjugation and reduce steric hindrance. The oriented probe demonstrated robust stability, exceptional specificity, and enhanced binding affinity, which were considered crucial for the detection of low-abundance targets. In concentration gradient tests, the orientational labelling method resulted in the lowest visible colorimetric signals at 10⁵ CFU·mL⁻¹, whereas conventional random probes (BSA–MNPs) resulted in detectable coloration at concentrations as low as 10⁶ CFU·mL⁻¹. The color sensitivity and LOD of the orientational labelling approach were further increased to 10⁴ CFU/mL and 0.668 × 10⁴ CFU/mL, respectively, through magnetic enrichment treatment. The capture binding kinetics analysis indicated that the enrichment efficiency depended on the binding effect of the antibody and the antigen concentration, showing a clear correlation with the dissociation constant (K_D). A clinical evaluation of 87 patient samples showed 88.5% agreement with the results of the quantitative fluorescence qPCR, which validated the diagnostic accuracy of the method. This study presents an orientational labelling platform for LFIA that combines Fc-directed antibody alignment with magnetic nanoparticle enrichment to overcome sensitivity barriers in the detection of low-abundance pathogens. This strategy comprises a universal design principle for achieving high-performance point-of-care testing (POCT) for various infectious diseases.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 10","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00604-025-07392-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145011522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of a novel Ag-ZnO@ZIF-8 soda biscuit-like heterostructure for high-performance ethylene glycol sensing","authors":"Leyao Bi,&nbsp;Boyan Fu,&nbsp;Jiahui Lin,&nbsp;Junsheng Wen,&nbsp;Jiaxing Fu,&nbsp;Wenyue Tian,&nbsp;Ningning Su,&nbsp;Binglin Zou,&nbsp;Chunjie Wang,&nbsp;Yue Wang","doi":"10.1007/s00604-025-07518-x","DOIUrl":"10.1007/s00604-025-07518-x","url":null,"abstract":"<div><p>Soda biscuit-like Ag-ZnO@ZIF-8 heterostructures were successfully synthesized using a secondary hydrothermal method for the first time, demonstrating exceptional ethylene glycol sensing performance. The sample (2-Methylimidazol (MeIm) concentration of 0.04 g) exhibits a remarkable response value of 1325.50 to 100 ppm ethylene glycol at 240 °C, along with a rapid response time of merely 7 s. Additionally, it displays outstanding gas selectivity (k = 28.63–696.90), great reproducibility and long-term stability. Further experiments indicate that the enhancement of the composite material’s gas sensing performance can be primarily attributed to the interfacial electron transfer effect, the abundance of oxygen vacancies, and the synergistic interactions within the heterostructures. Overall, this study lays a solid theoretical foundation for the practical detection applications of ethylene glycol and provides new insights into the research on gas sensors based on ZnO-organic frameworks.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 10","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145021594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}