Microchimica Acta最新文献

{"title":"Comparative aptamer screening for patulin and the development of sensitive colorimetric assay for fruit juice analysis","authors":"Haijun Pan,&nbsp;Ruijing Liu,&nbsp;Dongjie Liu,&nbsp;Lukai Ma,&nbsp;Qin Wang,&nbsp;Gengsheng Xiao,&nbsp;Feng Wang","doi":"10.1007/s00604-025-07591-2","DOIUrl":"10.1007/s00604-025-07591-2","url":null,"abstract":"<div><p> A gold nanoparticle-based colorimetric assay was developed for patulin, a mycotoxin, detection in fruit juice. Eight patulin-specific aptamers were rigorously screened using molecular docking and specific binding analyses to select the optimal candidate. The optimized assay exhibited a wide linear detection range of 5.0–200.0 ng/mL in the buffer reaction system and high specificity for patulin. Its reliability for real-world samples was validated by achieving good recoveries (83.6%-90.7%) in spiked apple and hawthorn juice, consistent with HPLC results. This study highlights an effective methodology for screening high-performance aptamers for food contaminants and a novel strategy for high-throughput food safety assessment targeting patulin.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"All-trans-retinal as a modulator of metabolic and mitochondrial signatures in non-tumorigenic and malignant breast cells: a Raman-based approach","authors":"Karolina Jarczewska,&nbsp;Monika Kopeć,&nbsp;Jakub Maciej Surmacki","doi":"10.1007/s00604-025-07571-6","DOIUrl":"10.1007/s00604-025-07571-6","url":null,"abstract":"<p>Retinoids are well recognized for their therapeutic potential in pharmacy and medicine. Although extensively studied for their anticancer properties, the specific effects of all-<i>trans</i>-retinal (ALTR) on the metabolism of breast cancer cells—particularly in relation to dose, incubation time, and tumour aggressiveness—remain insufficiently understood. In this study, the metabolic impact of ALTR on non-tumorigenic (MCF10A) and malignant breast cell lines (MCF7, MDA-MB-231) using Raman imaging and biological viability assays (XTT) were examined. Cells were incubated with 1 and 10 µM concentrations of ALTR for 24 and 48 h. Raman spectroscopy and imaging enabled both qualitative and quantitative detection of cellular organelles, allowing us to track ALTR-associated metabolic changes at the subcellular level. Our findings demonstrate that ALTR significantly reduced cell viability, particularly in cancerous lines, while promoting cellular development in non-tumorigenic MCF10A cells. Notably, a Raman band at 1597 cm⁻¹ appeared in MCF10A cells following ALTR treatment, potentially indicating metabolic conversion of ALTR into esterified forms. Furthermore, ALTR supplementation modulated the redox state of mitochondrial cytochrome <i>c</i>, as reflected by intensity changes in the 1583 cm⁻¹ band corresponding to its reduced form. These effects were most prominent in non-tumorigenic cells, suggesting enhanced sensitivity to ALTR-induced redox alterations. Collectively, our results highlight the value of Raman spectroscopy and imaging as powerful tools for cancer cell phenotyping and metabolic assessment. The observed inhibition of cancer cell proliferation, combined with alterations in mitochondrial redox balance, positions ALTR as a promising candidate for breast cancer therapy.</p>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00604-025-07571-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective electrochemical sensor for bisphenol A detection in wastewater using molecularly imprinted polymers on sustainable magnetic graphene oxide","authors":"Pablo Montoro-Leal,&nbsp;Maria del Mar Lopez Guerrero,&nbsp;Lourdes Mena-Herrera,&nbsp;Elisa Vereda Alonso,&nbsp;Antonio J. Ruiz-Sánchez,&nbsp;Rebeca Jiménez-Pérez","doi":"10.1007/s00604-025-07577-0","DOIUrl":"10.1007/s00604-025-07577-0","url":null,"abstract":"<div><p>A modified screen-printed carbon electrode (SPCE) has been developed for the determination of bisphenol A (BPA), a compound widely used in plastics and resins production, which can disrupt endocrine and reproductive human systems. Magnetic graphene oxide (MGO) was synthesized following a sustainable protocol based on mechanochemistry. Then, MGO was combined with a molecularly imprinted pyrrole-based polymer (MIPPy) for the preparation of a novel magnetic nanocomposite (BPA@MIPPy), characterized by several imaging, spectroscopic, and electrochemical techniques. The magnetic properties of BPA@MIPPy allowed the manipulation of the material, including separation, analyte preconcentration, and electrode modification. Differential pulse voltammetry (DVP) was the selected electrochemical technique for BPA detection, presenting high sensitivity (LOD = 29 nM, LOQ = 97 nM) and precision under optimum conditions. To study selectivity, the response of the sensor toward four potential interferents was evaluated (phenol, methanol, sodium nitrate, and ascorbic acid), and no interference was observed. Finally, a real wastewater sample was successfully analyzed, demonstrating that the method is adequate for water-control applications.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluorescence turn-on sensing and imaging of kinetin using tetralactam macrocycle-based supramolecular probe","authors":"Yi-Xuan He,&nbsp;Dan-Ni Tang,&nbsp;Chong-Ying Liao,&nbsp;Feng-Jiao Yang,&nbsp;Liu-Pan Yang,&nbsp;Li-Li Wang","doi":"10.1007/s00604-025-07583-2","DOIUrl":"10.1007/s00604-025-07583-2","url":null,"abstract":"<div><p>Kinetin (KT) is a crucial and widely used cytokinin; therefore, its dynamic detection and visualization are of significant importance. In this work, a water-soluble tetralactam macrocycle (TM)–based supramolecular probe was constructed for the in vitro detection and in vivo imaging of KT. Leveraging the excellent recognition of biomimetic TM toward KT, the sensitive and selective “turn-on” fluorescence detection of KT was realized in the range 2–200 μM with a limit of detection of 0.27 μM. The in vitro detection capacity of this supramolecular probe was validated in complex matrices, including potato extract and pesticides. Moreover, a portable visual sensing platform was further developed by integrating the supramolecular probe with hydrogel. Importantly, this supramolecular probe enables monitoring of the concentration distribution of KT through in situ fluorescence imaging, which may provide valuable insights into the physiopathological processes and action mechanisms of KT in plants. Furthermore, a sensor array was developed for discriminating between KT and other structure-similar cytokinins. This method holds great significance for cytokinin-related research.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective and sensitive anodic stripping voltammetric determination of Hg2⁺, Cu2⁺, and Pb2⁺ in food and water samples using a sulfur-doped graphitic carbon nitride–carbon dots nanocomposite modified screen-printed carbon electrode","authors":"Abdul Niaz,&nbsp;Hassan Elzain Hassan Ahmed,&nbsp;Muhammad Balal Arain,&nbsp;Mustafa Soylak","doi":"10.1007/s00604-025-07520-3","DOIUrl":"10.1007/s00604-025-07520-3","url":null,"abstract":"<div><p>A novel sulfur-doped graphitic carbon nitride with sulfur-doped carbon quantum dots (S-g-C₃N₄@S-CDs) nanocomposite was synthesized using 5-amino-1,3,4-thiadiazole-2-thiol as a precursor. The nanocomposite was synthesized using thermal condensation and hydrothermal techniques, which exhibited excellent physicochemical properties, as confirmed by X-ray diffraction (XRD), Fourier transform infrared (FTIR) and Field emission scanning-electron microscopy (FE-SEM) analyses. The prepared S-g-C₃N₄@S-CDs nantocomposite was employed to modify the surface of a screen-printed carbon electrode (SPCE) and was used as a novel electrochemical sensor for the sensitive detection of heavy metals in water and food samples. The electrochemical performance of S-g-C₃N₄@S-CDs was evaluated by cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Differential pulse anodic stripping voltammetry (DPASV) was employed for the simultaneous determination of Hg²⁺, Cu²⁺, and Pb²⁺ ions in 0.1 M HCl (pH, 1) as supporting electrolyte solution. The developed sensor exhibited excellent sensitivity due to the enhanced conductivity and electrocatalytic activity imparted by sulfur doping in the composite material. The linear ranges were 1.5 – 300.0 µgL⁻¹ for Hg²⁺, 16.0 – 600.0 µgL⁻¹ for Cu²⁺ and 26.0 – 1100.0 µgL⁻¹ for Pb²⁺ with the limits of detection (LOD) of 0.56 µgL⁻¹ (2.8 nM), 6.0 µgL⁻¹ (94.0 nm), and 10.0 µgL⁻¹ (48.3 nM) and sensitivity values of 5.5, 1.3 and 0.8 µA µgL⁻¹ cm⁻², respectively. The applications of the S-g- C₃N₄@S-CDs-based sensor for heavy metal ions were validated in food and water samples, which gave good recoveries in the range from 95.3% to 106.4%, with RSD values below 4.2%, demonstrating the good accuracy and precision of the developed sensor.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An environmental governance-oriented nanoplatform for persistent ultrasensitive SERS detection and photocatalytic elimination of organic dyes in water","authors":"Minzhe Li,&nbsp;Yuzhu Zhou,&nbsp;Guimei Wei,&nbsp;Wenyi Wang,&nbsp;Zhixing Liang,&nbsp;Changchun Wen,&nbsp;Xiang-Cheng Lin","doi":"10.1007/s00604-025-07606-y","DOIUrl":"10.1007/s00604-025-07606-y","url":null,"abstract":"<div><p>In practical applications, constructing bifunctional substrates with highly sensitive surface-enhanced Raman scattering (SERS) detection capabilities and environmentally friendly degradation technologies has significant importance in environmental remediation. Herein, Ag/CuO/CF (ACC) bifunctional composites were successfully fabricated via a two-step process. First, CuO nanowire arrays were grown in situ on a copper foam (CF) substrate using a facile thermal oxidation method. Subsequently, Ag nanoparticles were deposited uniformly onto the CuO nanowire surface via chemical reduction. As a SERS substrate, the ACC platform exhibited exceptional detection capabilities for methylene blue (MB) and malachite green (MG), achieving ultra-high sensitivity with remarkably high enhancement factors and extremely low detection limits for both target molecules. Moreover, the ACC substrates exhibited excellent uniformity, repeatability, and stability, as well as remarkable performance recovery in real sample testing. As a photocatalytic substrate, ACCs exhibited outstanding photocatalytic efficiency for degrading MB and MG, maintaining degradation of 91.97% after five cycles. Such a bifunctional design offers a novel approach for developing a new generation of intelligent environmental remediation technologies. It is particularly suitable for scenarios requiring on-site rapid analysis and immediate treatment, such as the monitoring and elimination of high-risk trace-level pollutants. Therefore, exploring integrated “detection-treatment” strategies holds significant importance for practical environmental applications.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging trends in 2D nanostructured electrode materials as enzyme-mimicking glucose sensors for biomedical diagnostics: a comprehensive review","authors":"Mani Arivazhagan,&nbsp;Paramasivam Shanmugam,&nbsp;Samikannu Prabu,&nbsp;Nagaraj Murugan,&nbsp;Yoong Ahm Kim,&nbsp;Rajaji Pavadai,&nbsp;Krishnamoorthy Shanmugaraj,&nbsp;Jaroon Jakmunee","doi":"10.1007/s00604-025-07573-4","DOIUrl":"10.1007/s00604-025-07573-4","url":null,"abstract":"<div><p>The development of nonenzymatic glucose sensors for biomedical diagnostics has gained new momentum due to recent developments in two-dimensional (2D) nanostructured materials. Two dimensional (2D) materials, these include transition metal dichalcogenides (TMDs), MXenes, metal–organic frameworks (MOFs), and graphene-based composites, are perfect candidates for enzyme-mimicking glucose detection because of their distinctive physicochemical characteristics, which include high surface area, a large signal to noise ratio (S/N), excellent electrical conductivity, higher thermal stability, and an abundance of active sites. This review emphasizes the new approaches to creating 2D nanostructured electrodes that mimic the catalytic activity of natural enzymes, with an emphasis on structural alterations, synthesis techniques, and electrochemical platform integration. Critical evaluation is done on the performance metrics, which include linear response ranges, sensitivity, detection limits, and selectivity in complex biological matrices of blood serum and urine samples. Additionally, the difficulties and potential for clinical translation of these biosensing platforms are also examined in detail. The revolutionary potential of 2D nanomaterials in developing next-generation, dependable, and reasonably priced glucose sensors for real-time biomedical diagnostics is highlighted by this comprehensive review.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145256353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green and structurally tailored synthesis of g-CNQDs for highly selective dopamine detection","authors":"Lu Wang,&nbsp;Ruizhe Wang,&nbsp;Bin Yang,&nbsp;Fei Zhang,&nbsp;Juan Zhao,&nbsp;Shaoming Wang,&nbsp;Ming Dong,&nbsp;Yue Cheng,&nbsp;Yan Li","doi":"10.1007/s00604-025-07588-x","DOIUrl":"10.1007/s00604-025-07588-x","url":null,"abstract":"<div><p>A facile and green one-step hydrothermal synthesis of graphitic carbon nitride quantum dots (g-CNQDs) using polyethylenimine (PEI) as a structure-directing agent is reported. The inherent structural features of PEI, including its branched architecture and abundant amine groups, drive a remarkable self-cyclization process that spontaneously generates triazine-based g-CNQDs exhibiting bright blue fluorescence. Unlike traditional synthetic strategies that involve complex procedures and hazardous reagents, our streamlined protocol produces g-CNQDs with a moderate quantum yield, outstanding aqueous dispersibility, and favorable biocompatibility. The resulting g-CNQDs exhibit exceptional sensing capabilities based on electrostatic interactions between their positively charged surfaces and negatively charged dopamine (DA) molecules. Upon binding, a stable non-fluorescent g-CNQDs-DA complex forms, generating a highly sensitive “turn-off” fluorescence response that correlates linearly with DA concentration. The developed probe achieves a low detection limit of 43 nM (S/N = 3) across a wide linear range of 0.1–300 μM. Validation in human urine and serum samples confirms the probe’s high selectivity for DA over potentially interfering biomolecules and metal ions, with recoveries ranging from 97 to 106%. This approach effectively addresses the challenges of green synthesis and selective detection, offering a promising platform for sustainable and specific fluorescent probes in diverse bioanalytical applications.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of PFAS and nanoplastics in serum by using Ag nanowires film SERS substrate with good reusability and sensitivity","authors":"Yansheng Liu,&nbsp;Yukun Sun,&nbsp;Guofu Wang,&nbsp;Xiaobo Jia,&nbsp;Jin Zhou,&nbsp;Hongqi Li,&nbsp;Hongli Li,&nbsp;Haixin Chan,&nbsp;Kang Li,&nbsp;Zhicheng Jin,&nbsp;Zhaoxu Li","doi":"10.1007/s00604-025-07585-0","DOIUrl":"10.1007/s00604-025-07585-0","url":null,"abstract":"<div><p> A novel surface-enhanced Raman spectroscopy (SERS)-based approach is introduced for the highly sensitive detection of perfluoroalkyl and polyfluoroalkyl substances (PFAS), polytetrafluoroethylene (PTFE), and polystyrene (PS) nanoplastics in serum samples using silver nanowire mesh (AgNWM) as SERS substrates. The surface-enhanced Raman scattering performance of AgNWM substrates was optimized using rhodamine 6G as a probe molecule, achieving a limit of detection (LOD) of 10⁻⁹ M. Serum samples were subjected to pre-treatment steps, including protein removal, sample enrichment, and concentration, enabling quantitative detection of multiple PFAS species at as low as 10⁻⁸ M. PTFE and PS nanoplastics were also successfully identified at a concentration of 100 ng·mL⁻¹. Furthermore, the AgNWM substrates exhibited significant stability and could be reused up to 10 times for plastic detection without substantial loss of sensitivity. This highly sensitive SERS platform provides an innovative and effective methodology for the detection of PFAS, PTFE, and PS nanoplastics in complex biological matrices, with considerable potential for clinical and environmental analyses.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145249212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A magnetic SERS aptasensor integrated with Fe3O4@SiO2-Au nanocomposites for high-throughput, sensitive, and selective detection of sulfonamides","authors":"Jinxin Liu,&nbsp;Zhili Gao,&nbsp;Han Fu,&nbsp;Cheng Tian,&nbsp;Pengfei Shi,&nbsp;Shusheng Zhang","doi":"10.1007/s00604-025-07568-1","DOIUrl":"10.1007/s00604-025-07568-1","url":null,"abstract":"<div><p> An innovative magnetic SERS aptasensor is presented that integrates Fe₃O₄@SiO₂-Au nanocomposites with aptamers, leveraging advancements in nanotechnology to overcome existing challenges. The aptasensor utilizes the magnetic Fe₃O₄ core for efficient separation from complex samples and the Au-decorated SiO₂ shell for signal enhancement via localized surface plasmon resonance. Moreover, aptamers with specificity for sulaquinoxaline (SQ), sulfamethoxypyridazine (SMP), and sulfamethoxydiazine (SMD) were used to enable selective recognition. Under optimized conditions, the detection limits of the aptasensor achieved were LOD_SQ = 33.26 pM, LOD_SMD = 63.11 pM, and LOD_SMP = 46.42 pM, with corresponding linear detection ranges of 0.1 nM to 50 μM, 0.1 nM to 50 μM, and 1 nM to 50 μM, respectively. It showed excellent selectivity against 11 interfering antibiotics and achieved recoveries  of 91.4%–119.0% in real water samples (tap water, lake water, drinking water, seawater, effluent, river aquaculture water bodies, water bodies in lake poultry breeding areas, and milk). Moreover, the aptasensor demonstrates reliable performance in detecting sulfonamides in actual water samples, indicating its potential for applications in food safety and environmental monitoring.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145243569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}