Microchimica Acta最新文献

{"title":"Fluorescent core–shell SiO2@COF composite for ultra-sensitive detection of cysteine and homocysteine","authors":"Wei Chen,&nbsp;Yaqin Chen,&nbsp;Han Fang,&nbsp;Li Wang,&nbsp;Zhihong Peng,&nbsp;Lili Chen","doi":"10.1007/s00604-024-06827-x","DOIUrl":"10.1007/s00604-024-06827-x","url":null,"abstract":"<div><p>To improve the fluorescence properties of covalent organic framework (COF) materials, core–shell SiO₂@COF composite was prepared, in which SiO₂ was used as inner substrate, and BMTH (2,5-bis (2-methoxyethoxy) p-phenylhydrazide) and HB (2-hydroxy-1,3,5-phenyltrialdehyde) acted as precursors to construct COF_BMTH-HB layer on the surface of SiO₂. Compared with COF_BMTH-HB, SiO₂@COF_BMTH-HB composite showed better dispersion property and improved fluorescence performance under the same experimental conditions. Using SiO₂@COF_BMTH-HB as a fluorescence probe, the fluorescence intensity was gradually decreased with the addition of Cu²⁺, while it was restored by introducing Cys or Hcy, realizing “ON–OFF-ON” fluorescence sensing detection. Other amino acids with five times the concentration of Cys showed little effect on the determination of Cys or Hcy. The SiO₂@COF_BMTH-HB-Cu²⁺ probe exhibited ultrahigh sensitivity and good selectivity for the detection of Cys and Hcy, with a detection range of 0.23 to 250.0 µM for Cys and 0.31 to 170.0 µM for Hcy. The detection limits (LOD = 3 σ/s) were 75 and 104 nM for Cys and Hcy, respectively. The system also showed a good recovery and low relative standard deviations in actual sample tests for Cys or Hcy, demonstrating its potential for practical applications.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142691870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemiresistive sensor array for quantitative prediction of CO and NO2 gas concentrations in their mixture using machine learning algorithms","authors":"Venkata Ramesh Naganaboina,&nbsp;Soumya Jana,&nbsp;Shiv Govind Singh","doi":"10.1007/s00604-024-06835-x","DOIUrl":"10.1007/s00604-024-06835-x","url":null,"abstract":"<div><p>Single sensors have been developed for specific gas detection in real-time environments, but their selectivity is limited by interference from other gases when considering mixtures of gases. Consequently, accurate detection of target gases in mixed gas environments is essential. Therefore, this study develops a sensor array approach to quantitatively estimate the concentration of carbon monoxide (CO) and nitrogen dioxide (NO₂) gases in their binary mixture (CO and NO₂). The sensor array consists of two different sensors, developed with zinc oxide and graphene-cobalt sulfide. The sensor array was tested in the presence of 29 different proportions of the binary mixture at room temperature. Subsequently, machine learning (ML) algorithms are applied on sensor signals to estimate the concentration of gases. The ML models unfortunately exhibited inaccurate prediction when all sensor signals were considered, therefore, to improve the prediction accuracy, the sensor signals were divided into three levels based on the mixed gas concentration regime. Interestingly, the classification and regression algorithms provided good classification accuracy (85.13 ± 3.2%) and reasonable predictions of target gas concentrations at three levels. The proposed computational framework can be extended to include additional gases in mixed gases and used in various applications, including automotive, industrial, and environmental monitoring.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conjugated hypercrosslinked polymers for in situ imprinting, selective sorption, and fluorescent turn-on sensing of oxalic acid","authors":"Ru-Yu Yan,&nbsp;Te-Ling Lu,&nbsp;Jian-Lian Chen","doi":"10.1007/s00604-024-06837-9","DOIUrl":"10.1007/s00604-024-06837-9","url":null,"abstract":"<div><p>Hypercrosslinked polymer (HCP) is a subclass of porous organic polymer possessing abundant microporosity, tailor-made functionality, and excellent stability. It features low-cost and easily direct knitting synthesis, facilitating the construction of π-conjugated frameworks with fluorescent properties by properly selecting building blocks (BBs) and linkers. Simultaneous imprinting of target molecules into the conjugated HCPs will create selective sorbents and sensors. We prepared several BBs to be polymerized with a terephthaloyl chloride (TCL) linker through Friedel–Crafts acylation in the presence of some imprinting molecules to clarify the best collocation for the advancement of imprinted polymer. With the highest increase in fluorescence intensity (<i>F</i>), the conjugated HCP comprised of dibenzofuran (DBF) and TCL was selected as contact with oxalic acid (OA). The OA-imprinted DBF-TCL (MICHP) was characterized by FTIR-approved structures, amorphous SEM images, TGA degradation at 390 °C, blue-shift emission, prolonged lifetime, and aggregation-caused quenching. The increase in <i>F</i> was proportional to OA concentration (0.17–20.0 μM, RSD = 1.6%, LOD = 0.03 μM) in THF/H₂O (pH 7.0) containing MICHP (0.2 mg/3 mL) and 6.0 min equilibrium. The <i>F</i> increase arose from inhibiting the quenching of photo-induced electron transfer because of protonation and association of OA with imprinted cavities. Langmuir–Freundlich isotherm precisely modeled the imprinted cavity affinity for OA with binding sites of 114.5 μmol/g and heterogeneity of 0.939. The cavities distinctly recognized OA and malonic acid interferant, presenting imprinting factor (4.76 vs. 1.35), specific sorption ratio (79.0% vs. 25.7%), and relative selectivity coefficient (3.935 vs. 0.779), which sustained the precise measurements of OA in tomato, taro, and urine. This study approved a cheap and easy strategy to implant fluorescent and imprinting functions in HCPs using as sorbent and sensor through Friedel–Crafts acylation of electrophilic crosslinker and nucleophilic BB, especially those with heterocyclics.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div><div><p>Scheme for the preparation of molecularly imprinted <i>π</i>-conjugated hypercrosslinked polymers (MICHP) and the change in fluorescence intensity of MICHP with the addition of oxalic acid</p></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142679877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functionalizing of magnetic nanoparticles as nano-architecture towards bioimaging and colorimetric recognition of MCF-7 cells: dual opto-sensing and fluorescence monitoring for early-stage diagnosis of breast cancer","authors":"Hadi Gheybalizadeh,&nbsp;Abolghasem Jouyban,&nbsp;Mohammad Hasanzadeh,&nbsp;Jafar Ezzati Nazhad Dolatabadi,&nbsp;Payam Shahbazi-Derakhshi,&nbsp;Zahra Golsanamlu,&nbsp;Jafar Soleymani,&nbsp;Saeedeh Khadivi-Derakhshan","doi":"10.1007/s00604-024-06826-y","DOIUrl":"10.1007/s00604-024-06826-y","url":null,"abstract":"<div><p>Considering the high incidence of breast cancer, a sensitive and specific approach is crucial for its early diagnosis and follow-up treatment. Folate receptors (FR), which are highly expressed on the epithelial tissue such as breast cancer cells (e.g., MCF-7), have been used in cancer diagnosis and bioimaging. This study presents an innovative colorimetric and fluorescence bioimaging platform towards MCF-7 using folic acid (FA)-conjugated iron-oxide magnetite silica-based nanocomposite (Fe₃O₄@SiO₂-3-aminopropyl)triethoxysilane (APTES-NH₂)@cysteine (Cyt)-Cyt@FA). For identification of MCF-7, the polyvinylpyrrolidone (PVP)-capped-platinum (Pt) nanoparticle was utilized as a nanozyme to catalyze the reaction between 3,3′,5,5′-tetramethylbenzidine (TMB) and H₂O₂ for visual detection of MCF-7 cells. Colorimetric changes are detectable by the naked eye and spectrophotometry at the wavelength of 450 nm, with a linear range of 50–5000 cells/mL and a detection limit of 30 cells/mL. The Fe₃O₄@SiO₂-APTES-NH₂@Cyt-Cyt@FA complex was modified with rhodamine B as a fluorescence bioimaging probe to monitor FR-overexpressed MCF-7 cells. The nanocomposite is biocompatible with a toxicity threshold of about 800 µg/mL. These methodologies facilitate bioimaging and colorimetric assays without sophisticated instrumentation, offering high specificity, sensitivity, repeatability, and stability, making them suitable as versatile methods for detecting and bioimaging cancer cells.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ZnO nanorods grown on Cu wire mesh provide a high sensitivity non-enzymatic absorbance glucose sensor","authors":"Quang Khai Dao,&nbsp;Thuy Quynh Mai,&nbsp;Thanh Van Pham,&nbsp;An Bang Ngac,&nbsp;Chi Hieu Hoang,&nbsp;Ewald Janssens,&nbsp;Hanh Hong Mai","doi":"10.1007/s00604-024-06845-9","DOIUrl":"10.1007/s00604-024-06845-9","url":null,"abstract":"<div><p> A highly sensitive non-enzymatic absorption-based glucose sensor is introduced that combines ZnO nanorods with the ferrous oxidation-xylenol orange (FOX) assay. ZnO nanorods were successfully synthesized on the surface of a copper wire mesh, exhibiting high crystallinity, purity, and a large surface area. The glucose sensor displays a high sensitivity of 0.394 mM⁻¹ in a wide linear detection range (0 − 6 mM), along with a low limit of detection of 0.25 mM. The proposed assay has an excellent selectivity towards glucose compared with other sugars such as sucrose, maltose, and fructose. The potential use of the non-enzymatic absorbance sensor for diabetes monitoring is demonstrated by measuring the glucose concentration in human blood serum, obtaining values that are consistent with clinical analysis.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142679558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An aptamer and hydroxyapatite-silver-zinc oxide–based novel electrochemical sensor for ultrasensitive H. pylori detection","authors":"Saima Rafique,&nbsp;Rizwan Akram,&nbsp;Rubina Nasir,&nbsp;Nafeesa Naz,&nbsp;Adnan Shafique,&nbsp;Shazia Bashir,&nbsp;Zeenat Haq","doi":"10.1007/s00604-024-06834-y","DOIUrl":"10.1007/s00604-024-06834-y","url":null,"abstract":"<div><p>Electrochemical biosensors offer a cost-effective way to identify <i>Helicobacter pylori</i> (<i>H. pylori</i>) (Hsp 60), responsible for stomach infections. The conductivity and surface area of the electrode were enhanced using Hap-Ag-ZnO composites on glassy carbon electrode (GCE) along with polythiophene (PP), as a conductive polymer to improve proficiency. The Hap-Ag-ZnO-PP composites have multiple functional group sites that facilitate aptamer immobilization on the GCE. This increases the sensitivity, stability, and dynamic range of the developed aptasensor. Electrochemical impedance spectroscopy, cyclic voltammetry, and square wave voltammetry were employed to examine the performance of the aptasensor. A linear behavior was observed for the modified electrode against the concentration of Hsp 60, showing a detection limit of 0.429 nM and a wide dynamic range of 0.05–300 nM. Moreover, the Hap-Ag-ZnO-PP-based aptasensor exhibits exceptional reproducibility, repeatability, fast response time (20 min), good selectivity, and excellent stability (electrochemical and storage). Therefore, the prepared sensitive aptasensor provides a promising platform for clinical diagnostics and <i>H. pylori</i> detection in real-world applications.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly-sensitive detection of CP-type synthetic cannabinoids from e-cigarettes by a novel Zn/Bi bimetallic organic framework-derived ZnO-Bi2O3 heterojunctions sensing platform","authors":"Haiou Chen,&nbsp;Ying He,&nbsp;Shimeng Duan,&nbsp;Anyun Xu,&nbsp;Meng Li,&nbsp;Yanming Ren,&nbsp;Ruilin Zhang,&nbsp;Xiangjun Yang,&nbsp;Shixiong Wang,&nbsp;Huiping Bai","doi":"10.1007/s00604-024-06832-0","DOIUrl":"10.1007/s00604-024-06832-0","url":null,"abstract":"<div><p>Synthetic cannabinoids (SCs), often masqueraded in “e-cigarettes,” are novel popular psychoactive substances with diverse structures and complex material compositions, making their detection more challenging for prompt intervention. Herein, a novel electrochemical sensing platform based on Zn/Bi bimetallic organic framework-derived ZnO-Bi₂O₃ heterojunctions was constructed for the detection of cyclohexanylphenol synthetic cannabinoids (CP-type SCs: CP47,497 and CP55,940). The sensing characteristics of ZnO-Bi₂O₃ were studied under various conditions, including solvent composition, molar ratio of metal, and calcination temperature. The optimized ZnO-Bi₂O₃ heterojunction exhibited a larger surface area, more active sites, and stronger stability, conducive to enhanced electrochemical catalytic performance. Under optimal conditions, a ZnO-Bi₂O₃ modified screen-printed electrode (ZnO-Bi₂O₃/SPE) showed good linear responses toward CP47,497 and CP55,940 within the concentration ranges 7 × 10⁻⁹ ~ 5 × 10⁻⁶ M and 1 × 10⁻⁹ ~ 5 × 10⁻⁶ M, with detection limits of 2.3 × 10⁻⁹ M and 3.3 × 10⁻¹⁰ M, respectively. The sensor also depicted excellent reliability and can be used for on-site electrochemical detection of target objects in e-cigarettes with high recovery. Finally, the electrochemical oxidation mechanisms of CP47,497 and CP55,940 were studied for the first time, and electrochemical fingerprints of CP-type SCs were speculated.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A facile optical sensing strategy for glyphosate detection based on structure-switching signaling aptamers","authors":"Ziping Liu,&nbsp;Xin Wang,&nbsp;Edith Bai,&nbsp;Yuhan Zhao,&nbsp;Shasha Liu,&nbsp;Zhiwei Xu,&nbsp;Qing Chang,&nbsp;Xinru Huang,&nbsp;Ye Tian","doi":"10.1007/s00604-024-06839-7","DOIUrl":"10.1007/s00604-024-06839-7","url":null,"abstract":"<div><p>A facile and highly specific optical sensing strategy is established for glyphosate (GLYP) detection using structure-switching signaling aptamers (F-SSSAs) with fluorescence signal reporting functionality. The strategy involves two domains: the FITC-labeled signal transduction domain for fluorescence signal reporting, while the functional domain (specific structure-switching aptamers) controls the target recognition. Graphene oxide (GO) works as a robust F-SSSAs quencher in the absence of GLYP. However, the F-SSSAs structure is switched in the presence of GLYP, prominently affecting the interaction with GO. The fluorescence of the structure-switching signaling aptamer-based sensing system is subsequently restored. The present strategy exhibits two dynamic linear relationships for GLYP detection in the ranges 0.2 to 80 ng·mL⁻¹ and 100 to 800 ng·mL⁻¹, with a low detection limit (LOD) of 0.07 ng·mL⁻¹. Significantly, the proposed sensing system has been successfully utilized to detect GLYP in water, soil, and rice, demonstrating its potential applications in GLYP monitoring.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly sensitive SERS-based lateral flow immunoassay of fipronil using bimetallic Au@Ag@Ag nanorods","authors":"Kseniya V. Serebrennikova,&nbsp;Nadezhda S. Komova,&nbsp;Lyubov V. Barshevskaya,&nbsp;Anatoly V. Zherdev,&nbsp;Boris B. Dzantiev","doi":"10.1007/s00604-024-06811-5","DOIUrl":"10.1007/s00604-024-06811-5","url":null,"abstract":"<div><p>A bimetallic core–shell-shell nanorods structure with gap-embedded Raman reporter 5,5′-dithio-bis-(2-nitrobenzoic acid) (DTNB) was developed and applied as a SERS-active nanotag in surface-enhanced Raman scattering lateral flow immunoassay (SERS-LFIA) of the insecticide fipronil. Due to the strong SERS signal of the Au^DTNB@Ag^DTNB@AgNRods, fipronil is detected with extremely low detection limit of 4.6 pg/mL. To the best of our knowledge, the proposed technique is the first SERS-LFIA of fipronil, proven to be effective in the selective determination of the target analyte and capable of detecting fipronil in a matrix of food samples (cucumber and apple juice) with recoveries of 97.0–117.0%. Moreover, the applied functionalization of the SERS nanotag with anti-species antibodies has provided a versatile immunoprobe that could improve performance of different LFIAs.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and utilization of mixed-metal (Zn/Cd) metal–organic frameworks for ultra-trace determination of diazinon and ethion via ion mobility spectrometry","authors":"Laleh Khorshidi,&nbsp;Behzad Aibaghi","doi":"10.1007/s00604-024-06830-2","DOIUrl":"10.1007/s00604-024-06830-2","url":null,"abstract":"<div><p>A novel mixed-metal (Zn/Cd) metal–organic framework-based dispersive solid-phase microextraction (MM-MOFs-DSPME) method was developed for the efficient extraction of organophosphorus pesticides, diazinon and ethion, from various environmental matrices. The detection of the extracted analytes was performed using ion mobility spectrometry. The synthesized mixed-metal (Zn/Cd) MOF was characterized using a comprehensive array of analytical techniques: Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDX), Brunauer–Emmett–Teller (BET) surface area analysis, X-ray photoelectron spectroscopy (XPS), and zeta potential measurement. This comprehensive characterization provided an in-depth understanding of the material’s structural and functional properties. Key parameters influencing the efficiency of the dispersive solid-phase microextraction (DSPME) method were optimized, including pH, type of desorption solvent, buffer type and volume, sorbent amount, and adsorption and desorption time. Under these optimal conditions, the linear dynamic ranges obtained were 0.5 to 300 ng mL⁻¹ for diazinon and 1.0 to 300 ng mL⁻¹ for ethion, with limits of detection of 0.15 ng mL⁻¹ and 0.29 ng mL⁻¹, respectively. Preconcentration factors of 74% and 78%, with extraction recoveries of 98.4–104.2% and 96.6–103.4%, were achieved for diazinon and ethion, respectively. The relative standard deviations, calculated based on ten replicate measurements, yielded values of 3.8% for diazinon and 3.9% for ethion at a concentration of 10 ng mL⁻¹, and 2.2% for diazinon, and 1.6% for ethion at a concentration of 150 ng mL⁻¹, respectively. The developed method was successfully applied to the quantification of the target pesticides in soil, water, and apple samples.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}