Microchimica Acta最新文献

{"title":"Fluorescence and colorimetric dual-signal sensing of resveratrol and ascorbic acid based on NaYF₄:Yb,Er@NaYF₄ upconversion nanoparticles","authors":"Le Ding,&nbsp;Huifang Bi,&nbsp;Hanqing Liu,&nbsp;Jing Xu,&nbsp;Tao Wang,&nbsp;Haifeng Zhou,&nbsp;Guangjun Zhou","doi":"10.1007/s00604-026-08077-5","DOIUrl":"10.1007/s00604-026-08077-5","url":null,"abstract":"<div><p>A novel dual-signal sensing platform is developed for the simultaneous quantitative determination of resveratrol (Res) and ascorbic acid (AA), integrating fluorescence-based quantification with colorimetric visual recognition, with a sensing mechanism based on the inner filter effect (IFE) of a composite system consisting of upconversion nanoparticles (UCNPs), 3,3’,5,5’-tetramethylbenzidine (TMB), and ferric ions (Fe³⁺). In this system, Fe³⁺ first oxidizes colorless TMB to blue oxidized TMB (oxTMB), and the formed oxTMB further quenches the fluorescence of the UCNPs through the IFE. When Res or AA is introduced into the system, oxTMB is reduced back to colorless TMB, which results in the fading of the blue solution and the recovery of UCNP fluorescence, thus achieving the dual-signal detection of the two analytes through fluorescence-based quantification and colorimetric qualitative determination. Furthermore, 4-hydroxy-TEMPO is introduced as an AA-specific scavenger, which can effectively eliminate the interference of AA and achieve selective discrimination between Res and AA. This developed sensing platform integrates the prominent merits of simple operation, high sensitivity, excellent specificity, and visual readout. It provides not only a novel analytical strategy for the efficient detection of Res and AA but also broad application prospects in the field of analytical chemistry.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 6","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147827670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bifunctionalized core–shell magnetic nanoparticles enabling catalytically amplified chemiluminescence for ultrasensitive detection of pyrophosphate ions","authors":"Congwen Ruan,&nbsp;Mengchun Tian,&nbsp;Lingfeng Gao,&nbsp;Zehao Li","doi":"10.1007/s00604-026-08096-2","DOIUrl":"10.1007/s00604-026-08096-2","url":null,"abstract":"<div><p>Luminol and Cu²⁺ bifunctionalized magnetic core-shell Fe₃O₄@Au nanoparticles (BFCS-Fe₃O₄@Au NPs) with high chemiluminescence (CL) efficiency were synthesized via an improved approach for pyrophosphate ions (PPi) sensing in complicated samples. First, a uniform Au shell was formed in situ on the Fe₃O₄ core through the controlled deposition enabled by luminol’s reducing property. This process also resulted in the immobilization of luminol molecules on the Au shell via Au-N coordination, where they functioned as the CL signal units. Subsequently, Cysteine (Cys) was modified onto the Fe₃O₄@Au surface via Au-S bonds, which introduced specific coordination sites for metal ions. Then, Cu²⁺ were captured by these sites and fixed onto the Fe₃O₄@Au surface, which efficiently catalyze the luminol-H₂O₂ reaction, resulting in a strong “signal-on” state. Finally, the presence of PPi could quantitatively quench this signal by competing with Cys for Cu²⁺ binding, thereby switching the system “off”. Due to this “signal-on-off” mechanism, an ultrasensitive sensor for PPi was developed, exhibiting a broad linear detection range from 0.1 nM to 10 µM and a low detection limit of 8.37 pM. This sensing strategy provides a reliable and promising pathway for PPi monitoring in biological analysis and environmental water analysis.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 6","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147827671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid Bi/AuNP-enabled laser-induced graphene sensor for flexible and simultaneous detection of Zn²⁺ and Cd²⁺ in seawater and soil samples","authors":"Neha,&nbsp;Mansoor Ahmad,&nbsp;Brij Mohan,&nbsp;Wang Baoli,&nbsp;Wei Sun","doi":"10.1007/s00604-026-08102-7","DOIUrl":"10.1007/s00604-026-08102-7","url":null,"abstract":"<div><p>A flexible sensor has been developed comprising a bismuth film and a gold nanoparticle-decorated laser-induced graphene electrode (Bi/AuNP/LIGE) for the concurrent detection of Zn²⁺ and Cd²⁺ using differential pulse anodic stripping voltammetry (DPASV). The sensor was thoroughly characterized, and the key experimental parameters, including buffer composition, deposition potential, accumulation time, and pH, were systematically optimized. The optimal performance was achieved in borate buffer (pH 7.5) with a deposition potential of -1.1 V and an accumulation time of 150 s. Under these conditions, the detection limits are 0.072 µM for Zn²⁺ and 0.031 µM for Cd²⁺, with quantification limits of 0.24 µM and 0.103 µM, respectively. The sensor demonstrates good reproducibility and accuracy when tested on seawater and soil samples. These findings show that the Bi/AuNP/LIGE platform offers enhanced sensitivity and selectivity, paving the way for advanced sensors in portable, on-site monitoring systems.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 6","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147827672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magneto-electrochemical biosensing for pathogen detection using nuclease-responsive nanohybrids","authors":"Gunes Kibar,&nbsp;Murat Kavruk,&nbsp;Frank J. Hernandez,&nbsp;Baris A. Borsa,&nbsp;Ali Dogan Dursun,&nbsp;Veli Cengiz Ozalp","doi":"10.1007/s00604-026-08087-3","DOIUrl":"10.1007/s00604-026-08087-3","url":null,"abstract":"<div><p>The development of sustainable and highly sensitive diagnostic platforms is critical for rapid pathogen identification and effective disease management. Here, a green, magneto-electrochemical biosensing strategy is reported for the selective detection of <i>Streptococcus pneumoniae</i> based on pathogen-specific nuclease activity. Uniform organic–inorganic hybrid polyhedral oligomeric silsesquioxane (POSS) nanoparticles were synthesized via an ultrafast UV-initiated emulsion polymerization within 5 min using an eco-friendly approach. The nanoparticles were sequentially functionalized by in situ deposition of superparamagnetic iron oxide nanoparticles and biomimetic polydopamine coating, enabling robust and high-density immobilization of nuclease-responsive oligonucleotide probes. The resulting PDA@SPION/POSS nanohybrids exhibit controlled size, preserved structural integrity, and strong superparamagnetic behavior, allowing efficient magnetic manipulation and electrochemical signal transduction. Upon exposure to <i>S. pneumoniae</i>, nuclease-mediated probe cleavage produces a pronounced electrochemical response, enabling label-free detection over a wide dynamic range (10²–10⁸ CFU mL⁻¹) with a detection limit of 10² CFU mL⁻¹. High selectivity against non-target bacteria highlights the specificity of the enzymatic recognition mechanism. This work establishes a sustainable and amplification-free biosensing platform with strong potential for rapid clinical diagnostics.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 5","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00604-026-08087-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147809333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual colorimetric detection platform of Salmonella typhimurium based on PtRu@ZrFe-MOFs nanozymes integrated with 3D-printed microchannel device","authors":"Hongtao Zhou,&nbsp;Zebin Zhang,&nbsp;Huan Zhang,&nbsp;He Sun,&nbsp;Jinglei Liu,&nbsp;Xin Fang,&nbsp;Nan Li,&nbsp;Zhuo Hao,&nbsp;Na Lv,&nbsp;Jiayu Wan","doi":"10.1007/s00604-026-08090-8","DOIUrl":"10.1007/s00604-026-08090-8","url":null,"abstract":"<div><p>Quantitative detection of <i>Salmonella typhimurium</i> is of vital importance for promoting food safety monitoring and control. This study successfully developed a 3D-printed microchannel device that integrates cleaning and detection functions, enabling sensitive and semi-automatization colorimetric detection of <i>Salmonella typhimurium</i>. Firstly, the magnetic beads modified monoclonal antibody (MBs-Anti), <i>Salmonella typhimurium</i> and PtRu@ZrFe-MOFs@Apt nanozymes were successively added to the centrifuge tube to facilitate the formation of the MBs-Anti-<i>Salmonella typhimurium</i>-PtRu@ZrFe-MOFs@Apt sandwich complex. Then, the above incubated mixture was injected into the reaction tank of the microchannel device and washed with PBS containing hydrogen peroxide to separate the sandwich complex from the impurities in the sample solution. Subsequently, the TMB substrate solution was added to facilitate the catalytic oxidation of the sandwich complex, thereby forming the blue oxidized TMB product. The RGB image of the blue product was captured using a portable smartphone device, and the colorimetric signal of the image was analyzed to determine the concentration of <i>Salmonella typhimurium</i>. The microchannel device can detect <i>Salmonella typhimurium</i> within a concentration range 10¹ to 10⁶ CFU/mL within 75 min, with a detection limit of 3.3 CFU/mL. It is worth noting that the 3D-printed microchannel device constructed has good universality. By replacing the corresponding antibodies, aptamers and other biological recognition elements, it can be extended to the detection of other pathogenic bacteria.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 5","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147809313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction a novel photoelectrochemical aptasensor based on multivariate copper-based metal-organic framework for the efficient detection of tetracycline","authors":"Lina Wang,&nbsp;Yan Shen,&nbsp;Zhaopeng Li,&nbsp;Fenghe Duan,&nbsp;Chuanpan Guo,&nbsp;Shuai Zhang,&nbsp;Bin Hu,&nbsp;Zhihong Zhang","doi":"10.1007/s00604-026-08088-2","DOIUrl":"10.1007/s00604-026-08088-2","url":null,"abstract":"<div><p>Chronic tetracycline (TET) exposure in water/food triggers drug resistance, immune damage and allergies, requiring rapid, sensitive TET detection to safeguard food and human safety. Herein, a novel photoelectric active multivariate copper-based metal-organic framework (Cu-MOF) constructed from tetra(4-carboxyphenyl)porphine (TCPP) and 5,10,15,20-tetra(4-pyridyl)porphyrin (TPyP) (denoted as Cu-TCPP/TPyP) was employed as the bioplatform for the fabrication of a photoelectrochemical (PEC) aptasensor for the efficient detection of TET. The Cu-TCPP/TPyP was synthesized via the coprecipitation method using TCPP and TPyP as dual ligands and copper ions as the metal precursor. Due to the dual-coordination metal nodes, the attained Cu-TCPP/TPyP possessed rich defects, large pore size, and high specific surface area relative to Cu-MOFs prepared using the sole ligand. The Cu-TCPP/TPyP also showed enhanced photoelectric conversion efficiency due to the suppressed combination of electron-hole pair, enhanced visible light utilization, and high carrier density. The manufactured Cu-TCPP/TPyP-based PEC aptasensor thus exhibited the ultralow limit of detection of 0.76 fg mL^–1 toward TET within the concentration from 1 fg mL^–1 to 10 ng mL^–1, markedly lower than most reported TET biosensors. In view of the high selectivity, good reproducibility, and high long-term stability, the constructed aptasensor possesses wide practicability for the sensitive determination of TET in diverse samples, which was also confirmed by the standard conventional determination method. The presented PEC aptasensor puts forward the advancement of the MOF-based biosensor in the field of the analysis of food safety.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 5","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147796336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A phthalocyanine‑derived covalent organic framework nanoplatform with boosted sonodynamic efficacy for apigenin co‑delivery and combined antitumor therapy","authors":"Haocong Sun,&nbsp;Yaoyao Liu,&nbsp;Yunqian Han,&nbsp;Ziqian Xu,&nbsp;Haochen Li,&nbsp;Qian Zhang,&nbsp;Ke Zheng,&nbsp;Caifeng Ding","doi":"10.1007/s00604-026-08074-8","DOIUrl":"10.1007/s00604-026-08074-8","url":null,"abstract":"<div><p>Sonodynamic therapy (SDT), characterized by its non-invasiveness and high tissue penetration depth, has emerged as a promising novel antitumor treatment modality. Nevertheless, the development of efficient sonosensitizers for SDT still poses a challenge. In this study, a covalent organic framework based on zinc phthalocyanines (ZnPc-COF) was synthesized. It was discovered that ZnPc-COF exhibited significantly enhanced sonodynamic activity compared to free ZnPc. This study focuses on the adverse impacts of highly expressed HIF-1α at tumor sites on tumor treatment. Therefore, by leveraging the porous structure of ZnPc-COF, we adsorbed HIF-1α inhibitor apigenin (API) and modified the surface of ZnPc-COF with polyethylene glycol (PEG) and the targeting peptide TAT (trans-activator of transcription) to obtain the final product ZnPc-COF/API@DSPE-TAT. The research indicates that ZnPc-COF/API@DSPE-TAT possesses excellent sonodynamic activity and demonstrates a combined cytotoxic effect of SDT and API. In in vivo experiments, it was confirmed that ZnPc-COF/API@DSPE-TAT has remarkable tumor-targeting ability, significantly reduces HIF-1α level in tumors, and can effectively inhibit tumor growth. The construction mechanism and combined antitumor strategy of ZnPc-COF/API@DSPE-TAT offer theoretical and practical guidance for the development of new sonosensitizers.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 5","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147796337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerium-doped carbon dots for multifunctional biomedical applications: enhanced heavy metal sensing, antioxidant-driven wound healing, and RAFT polymer–mediated improved gene complexation capability","authors":"Sumedha Das,&nbsp;Souptik Dutta,&nbsp;Kishor Sarkar","doi":"10.1007/s00604-026-08094-4","DOIUrl":"10.1007/s00604-026-08094-4","url":null,"abstract":"<div><p>Highly fluorescent cerium-doped carbon dots (Ce-CDs) were synthesized via a facile hydrothermal process using citric acid, urea, and cerous nitrate hexahydrate. Cerium incorporation markedly enhanced the fluorescence intensity and introduced a unique time-dependent colour evolution from dark green to red. The Ce-CDs exhibited selective heavy metal ion sensing behaviour, where Hg²⁺ caused an increase in absorbance intensity along with a blue shift of the absorption maximum, whereas Cd²⁺ and Pb²⁺ induced pronounced absorbance quenching. Beyond sensing, Ce-CDs demonstrated superior antioxidant activity in 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays compared to CDs, reflecting the contribution of the Ce³⁺/Ce⁴⁺ redox couple. This enhanced radical scavenging capability translated into improved biological performance. In vitro scratch assays using L929 fibroblast cells revealed complete wound closure within 24 h at Ce-CD concentrations of 50 and 100 µg/mL, while undoped CDs failed to achieve full healing under identical conditions. In addition, Ce-CDs showed significantly stronger antibacterial activity against <i>Escherichia coli</i>. To enable gene complexation capability, an amino acid–rich RAFT (Reversible Addition-Fragmentation Chain-Transfer) polymer, poly(hydroxyethyl methacrylate–phenylalanine–NH₂) (PHPA-NH₂), was conjugated onto Ce-CDs via carbodiimide coupling. Successful conjugation was confirmed by FTIR spectroscopy and a surface charge reversal from − 16.1 mV to + 40.5 mV. The resulting PHPA-NH₂@Ce-CDs efficiently condensed DNA at weight ratios ≥ 10:1, as confirmed by gel electrophoresis. Overall, cerium doping and polymer functionalization synergistically transform carbon dots into a multifunctional nanoplatform with strong potential for heavy metal sensing, wound healing, antibacterial therapy, and potential non-viral gene delivery platform applications. </p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 5","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147796378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a rapid calcium testing strip with metal-enhanced fluorescence for early detection of hypocalcemia in dairy cattle","authors":"Lian Miller,&nbsp;Huiyan Li","doi":"10.1007/s00604-026-08089-1","DOIUrl":"10.1007/s00604-026-08089-1","url":null,"abstract":"<div><p>Hypocalcemia (milk fever) is a severe metabolic disease in dairy cattle, affecting up to 50% of multiparous cows postpartum and leading to significant economic losses and increased risk of secondary disorders. Rapid, low cost, and on-site detection of low blood calcium levels (&lt; 1.1 mM) is needed for timely intervention, yet current diagnostic methods are costly, complex, or require centralized laboratory analysis, delaying treatment. This study addresses the need for a simple, rapid, and cost-effective diagnostic tool by developing a gold nanoparticle-functionalized test strip for the quantification of ionized calcium (Ca²⁺) in bovine plasma and milk. The assay uses the Ca²⁺-sensitive fluorescent dye Fluo-5 N, with gold nanoparticles (AuNPs) integrated into nitrocellulose membrane to amplify the fluorescent signal based on the metal-enhanced fluorescence (MEF) effect. This test is designed for rapid, dip-and-read operation. Optimal assay performance was achieved through a simple, scalable fabrication process costing an estimated $0.14 CAD per strip and yielding a rapid 30-second readout after sample application. MEF optimization demonstrated a threefold increase in fluorescence intensity compared to controls without AuNPs. The test strip established strong linear correlations across clinically relevant dilutions in bovine plasma (R² = 0.981) and skim milk (R² = 0.941), with 95.0% to 108.6% recovery across different milk dilutions and an average recovery of 96.7% in skim milk, confirming its robustness against matrix effects in the target biological fluids. The functional detection range, spanning from a limit of detection of 431µM to 1.1 mM, and with a limit of quantification of 616 μM, effectively covering the critical diagnostic window for subclinical hypocalcemia (&lt; 1.1 mM). Additionally, the test strips demonstrated long-term stability, maintaining performance for at least 120 days when stored at 4 °C. Lastly, the simple dipping-based sample application was validated as statistically equivalent to pipetting, showing potential for adaptation to farm use. This simple, portable technology could significantly improve herd health management with the potential to enable rapid, on-site screening for subclinical hypocalcemia, facilitating early treatment, and reducing the economic burden due to milk fever.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 5","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oxygen vacancy-enriched Cr2O3 wrinkled biomimetic architecture via shell of metaplexis japonica for rapid recovery and sensitive detection of butylmercaptan vapor","authors":"Yu-Jia Zhu,&nbsp;Hui-Nan Lei,&nbsp;Ming-Yan Cao,&nbsp;Yan Liu,&nbsp;Zhao-Peng Deng,&nbsp;Xian-Fa Zhang,&nbsp;Ying-Ming Xu,&nbsp;Li-Hua Huo,&nbsp;Shan Gao","doi":"10.1007/s00604-026-08079-3","DOIUrl":"10.1007/s00604-026-08079-3","url":null,"abstract":"<div>\u0000 \u0000 <p>Biomimetic architecture materials with abundant pores and oxygen vacancies hold great promise for boosting gas-sensing performance, yet not utilized for highly efficient detection of toxic butyl mercaptan (BM) vapor. For this purpose, the shell of metaplexis japonica template was employed as a structure-directing template for the controllable synthesis of three biomimetic Cr₂O₃ materials <i>via</i> a facile process involving impregnation with aqueous chromium nitrate solution followed by air calcination. Among them, Cr₂O₃-500 material obtained by calcination at 500 °C features wrinkled architecture replicated from uniformly small-size nanoparticles, coupled with abundant pores and surface oxygen vacancies. The cooperation among these microstructural characteristics not only accelerates the diffusion of gas molecules to the sensing layer, but also increases the number of adsorption sites for surface reaction and the concentration of surface adsorbed oxygen species, thereby effectively enhancing the highly selective and sensitive response to trace BM vapor at low operating temperature. At the optimal temperature of 133 °C, the Cr₂O₃-500 sensor delivers a high response of 247.8 toward 100 ppm BM, along with the response/recovery times of 86 s/51 s. Furthermore, it also presents favorable selectivity, reversible response-recovery behavior, as well as satisfactory moisture tolerance and stability. Additionally, the sensing mechanism underlying the trace BM detection was investigated in detail by combining multiple characterization techniques.</p>\u0000 <span>AbstractSection</span>\u0000 Graphical Abstract\u0000 <div><figure><div><div><picture><source><img></source></picture><span>The alternative text for this image may have been generated using AI.</span></div></div></figure></div>\u0000 \u0000 </div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 5","pages":""},"PeriodicalIF":5.3,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}