Preparation of octyl-modified silica isoporous membrane for hydrophobic enrichment and electrochemical detection of methylmercury in aquatic products

IF 5.3 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchimica Acta Pub Date : 2025-04-24 DOI:10.1007/s00604-025-07169-y

Guiyun Zhang, Zhiwei Lai, Jianhua Xie, Weiqiang Yang

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引用次数: 0

Abstract

Methylmercury (CH₃Hg⁺), a lipophilic environmental pollutant, accumulates in fish, shellfish, and other organisms, posing significant risks to human health through the food chain. Developing a convenient and sensitive analytical method for CH₃Hg⁺ detection is crucial for reducing costs and enhancing the efficiency of food safety testing. In this study, we prepared an octyl-modified silica isoporous membrane on the indium tin oxide (ITO) electrode (Octyl-SIM/ITO) via the electrochemical-assisted self-assembly (EASA) method using octyltrimethoxysilane (O-TES) as the functional organosilane. The Octyl-SIM/ITO electrode exhibits vertically-ordered nanochannels and strong hydrophobic affinity, enabling selective penetration and enrichment of weakly polar analytes. Utilizing square wave anodic stripping voltammetry (SWASV), the Octyl-SIM/ITO electrode demonstrates superior electrochemical response signals for CH₃Hg⁺ detection, achieving a detection limit as low as 4 nM. This method allows for accurate and reproducible detection of CH₃Hg⁺ in fish and oyster samples with minimal sample preparation, offering promising potential for portable in situ detection.

Graphical Abstract

查看原文本刊更多论文

制备疏水富集和电化学检测水产品中甲基汞的辛基改性二氧化硅异孔膜

甲基汞（CH3Hg+）是一种亲脂性环境污染物，可在鱼类、贝类和其他生物中积累，通过食物链对人类健康构成重大风险。开发一种方便、灵敏的CH3Hg+检测方法对于降低食品安全检测成本和提高检测效率至关重要。在本研究中，我们以辛基三甲氧基硅烷（O-TES）为功能有机硅烷，通过电化学辅助自组装（EASA）方法在氧化铟锡（ITO）电极（Octyl-SIM/ITO）上制备了辛基修饰的二氧化硅异孔膜。Octyl-SIM/ITO电极具有垂直有序的纳米通道和较强的疏水性，可选择性穿透和富集弱极性分析物。利用方波阳极溶出伏安法（SWASV）， Octyl-SIM/ITO电极在CH3Hg+检测中表现出优异的电化学响应信号，检测限低至4 nM。该方法可以精确和重复地检测鱼和牡蛎样品中的CH3Hg+，只需最少的样品制备，为便携式原位检测提供了很好的潜力。图形抽象

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来源期刊

Microchimica Acta 化学-分析化学

CiteScore

9.80

自引率

5.30%

发文量

410

审稿时长

2.7 months

期刊介绍： As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.