Microchimica Acta最新文献

{"title":"Inkjet-printed paper-based electrochemical cell with a molecularly imprinted polymer for omeprazole detection in water","authors":"Isabel Seguro,&nbsp;Verónica Poza-Nogueiras,&nbsp;Iván González-Veloso,&nbsp;M. Natália D. S. Cordeiro,&nbsp;Cristina Delerue-Matos,&nbsp;João G. Pacheco","doi":"10.1007/s00604-026-08446-0","DOIUrl":"10.1007/s00604-026-08446-0","url":null,"abstract":"<div><p>A simple and low-cost inkjet-printed paper-based electrochemical cell incorporating a molecularly imprinted polymer (MIP) was developed for the selective detection of omeprazole (OPZ). Waterproof paper was used as the substrate for the fabrication of the electrochemical cell by inkjet printing of silver and gold conductive inks, followed by modification of the working electrode with carbon ink. The resulting cell showed good electrochemical performance, with an enhanced voltammetric response towards OPZ compared with conventional screen-printed electrodes. Printing parameters and electrode composition were optimised, and the morphology was confirmed by scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS). The functional monomer was rationally selected through computational studies based on BSSE-corrected binding energies, avoiding a trial-and-error approach. The recognition element was then obtained by electropolymerisation of p-aminobenzene sulfonic acid in the presence of OPZ, forming an imprinted polymer directly on the electrode surface. Under optimised conditions, the sensor exhibited a linear response between 0.50 and 50 µM, with limits of detection and quantification of 0.14 µM and 0.47 µM, respectively, and good selectivity against structurally related compounds. The cell was successfully applied to spiked river and well water samples, without any pre-treatment, achieving recoveries ranging from 89% to 112%. Combining simple fabrication, low cost and portability, this inkjet-printed paper-based MIP sensor shows strong potential for the on-site monitoring of pharmaceutical contaminants.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 11","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149132655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colorimetric/chemiluminescent vertical flow immunoassay based on multifunctional cobalt–gold bimetallic nanoclusters for Brucella antibody detection and deep learning-assisted semiquantitative analysis","authors":"Hamai Bi,&nbsp;Xiaogang Zhao,&nbsp;Mingjie Wei,&nbsp;Xia Li,&nbsp;Jiahui Wu,&nbsp;Yuankun Wang,&nbsp;Xindi Zhang,&nbsp;Halifei Ma,&nbsp;Hengxuan Zhou,&nbsp;Zhihua Xu,&nbsp;Kedong Guo,&nbsp;Yali Jiang,&nbsp;Feng Shi","doi":"10.1007/s00604-026-08444-2","DOIUrl":"10.1007/s00604-026-08444-2","url":null,"abstract":"<div><p>A colorimetric/chemiluminescent vertical flow immunoassay (VFI) for Brucellosis was developed using glutathione-protected cobalt–gold nanoclusters conjugated with staphylococcal protein A (GSH@Co–AuNCs–SPA) as multifunctional catalytic immunoprobes. The nanocluster probe integrates antibody recognition with peroxidase-like catalytic activity, enabling three complementary signal readouts within a common immunorecognition architecture: direct colorimetric visualization, TMB–H₂O₂-amplified colorimetry, and luminol–H₂O₂ chemiluminescence.</p><p>The prepared GSH@Co–AuNCs exhibited H₂O₂-mediated catalytic activity and sustained chemiluminescent emission, with a detectable visual signal persisting for more than 150 min, thereby providing a broad acquisition window for low-background imaging. Serial-dilution experiments showed experimentally determined signal-discrimination thresholds of 0.5 IU mL⁻¹ for direct colorimetry and 0.2 IU mL⁻¹ for both TMB-amplified colorimetry and chemiluminescence. For the chemiluminescent mode, analysis of 20 independent blank measurements yielded a statistical limit of detection of 0.134 IU mL⁻¹. Under the same analytical dilution-series conditions, a commercial colloidal-gold lateral-flow assay produced a visually distinguishable signal down to 20 IU mL⁻¹.</p><p>To improve the consistency of image interpretation, shared-weight dual-branch ResNet-18 regression models were established for both TMB and chemiluminescent images. Grouped five-fold cross-validation yielded mean R² values of 0.8746 ± 0.0784 and 0.8907 ± 0.0588, with four-level grading accuracies of 96.25 ± 2.10% and 93.00 ± 6.28% for the TMB and chemiluminescent models, respectively. In a preliminary evaluation of 30 clinical serum samples, TMB-amplified colorimetry showed 95.0% sensitivity, 90.0% specificity, and 93.3% overall agreement with the serum agglutination test (SAT), whereas chemiluminescence showed 95.0%, 100%, and 96.7%, respectively.</p><p>The proposed platform integrates catalytic signal amplification, complementary optical readouts, and regression-based semiquantitative interpretation within a single VFI system. This strategy provides a practical framework for improving weak-signal discrimination and standardized interpretation in rapid anti-<i>Brucella</i> antibody screening, while further validation in larger independent clinical cohorts remains necessary.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 11","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149132653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A ratiometric fluorescence sensor based on HFeO-modified NH2-MIL-101(Fe) and Ru-embedded for supersensitive and visual detection of As(V) in water","authors":"Fengqin Yin,&nbsp;Xudong He,&nbsp;Xueting Liu,&nbsp;Dong Guo,&nbsp;Jiahui Wang,&nbsp;Xinxin Cui,&nbsp;Zongping Fang,&nbsp;Tai Ye,&nbsp;Hui Cao,&nbsp;Liling Hao,&nbsp;Fei Xu","doi":"10.1007/s00604-026-08441-5","DOIUrl":"10.1007/s00604-026-08441-5","url":null,"abstract":"<div><p>An enhanced ratiometric fluorescence sensor Ru@HFeO@NH₂-MIL-101 (Fe) for the determination of arsenate was constructed by using HFeO-modified NH₂-MIL-101 (Fe) as the response signal and Ru(bpy)₃²⁺ as the reference signal, which can be used for sensitive and visual detection of As(V). Because the HFeO nanoparticles were cleverly in-situ generated within the NH₂-MIL-101(Fe) framework, the adsorption capacity of As(V) was enhanced 32% and further increased fluorescence ratio. The sensor exhibited a good linear relationship within As(V) concentration range 0.05-1 and 3–30 µM, with a detection limit (LOD) of 0.039 µM. The sensor also exhibited good selectivity and practical application performance, and can be utilized by a smartphone for visual detection of As(V). This provides an effective method for the sensitive detection of As(V) in complex environmental conditions.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 11","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149132908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Entropy-driven amplification combined with CRISPR-Cas12a to develop a dual-mode biosensor for breast cancer miR-155 detection","authors":"Yihua Wang,&nbsp;Min Lan,&nbsp;Min Zhong,&nbsp;Hui Jiang,&nbsp;Qi Wang,&nbsp;Jinbo Liu,&nbsp;Baolin Li","doi":"10.1007/s00604-026-08451-3","DOIUrl":"10.1007/s00604-026-08451-3","url":null,"abstract":"<div><p>An entropy-driven amplification (EDA) coupled CRISPR-Cas12a dual-mode biosensor was established for sensitive detection of breast cancer biomarker miR-155. Fluorescent quantitative detection proceeds via synchronous single-tube isothermal incubation without liquid transfer, while colorimetric visual screening requires post-reaction addition of chromogenic substrates. The system eliminates reverse transcription for direct miRNA recognition and realizes cascade dual signal amplification, which greatly accelerates the apparent signal generation rate constant compared with standalone EDA. Under optimized conditions, the fluorescent mode achieves a limit of detection of 660 fM with linear quantification from 60 to 800 pM, and the colorimetric branch provides visual readout with a logarithmic linear range of 4–400 nM. The sensor shows favorable anti-interference performance in diluted healthy human serum spike-recovery tests and can realize intracellular in situ miR-155 fluorescence imaging to distinguish breast cancer cells from normal mammary epithelial cells. We systematically optimized all reaction parameters, supplemented comprehensive specificity verification including mismatched sequences, and supplemented detailed kinetic and analytical characterization to support the reliability of this dual-mode nucleic acid sensing platform.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 11","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149098994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solid-state electrochemiluminescence sensor based on functional covalent organic frameworks for detecting Co2+ ions","authors":"Guangyan Liu,&nbsp;Haonan Gao,&nbsp;Jiali Li,&nbsp;Wei Xie,&nbsp;Shili Hou","doi":"10.1007/s00604-026-08439-z","DOIUrl":"10.1007/s00604-026-08439-z","url":null,"abstract":"<div><p>The application of covalent organic frameworks (COFs) in electrochemiluminescence (ECL)-based detection of environmental pollutants remains relatively underexplored, particularly with respect to achieving high recognition efficiency. In this work, a series of imine-linked functional COFs were constructed using tetrakis(4-aminophenyl)ethene as the C4 building block, with precisely regulated molar ratios of 2,2'-bipyridine-5,5'-dicarbaldehyde (BPYDAH, recognition unit) and 2,2'-bithiophene-5,5'-dicarbaldehyde (BTA, luminescence unit) as co-monomers. All as-prepared COFs exhibited stable solid-state ECL emission in the presence of tri-n-propylamine as a co-reactant, and their ECL intensity showed a positive correlation with the proportion of BTA units in the framework. Among the series, COF1-3 with optimized monomer ratio simultaneously maintained satisfactory ECL emission and specific Co²⁺ recognition capability, thus was selected as an ECL probe to fabricate a solid-state COF1-3/GCE ECL sensor. The constructed sensor achieved linear detection of Co²⁺ in the range of 4.0 × 10⁻⁷ to 2.0 × 10⁻⁵ mol L⁻¹ with a detection limit of 3.8 × 10⁻⁷ mol L⁻¹, and was successfully applied to Co²⁺ detection in real environmental water samples with satisfactory recoveries.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 11","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149132548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An aptamer-controlled Mn-Au nanozyme for H2O2-free and smartphone-assisted colorimetric detection of mercury ions","authors":"Chen Ma,&nbsp;Yida Zhang,&nbsp;Shuai Mu,&nbsp;Yuan Zhang,&nbsp;Shuoyun Wei,&nbsp;Quanfang Li,&nbsp;Shufang Ren","doi":"10.1007/s00604-026-08425-5","DOIUrl":"10.1007/s00604-026-08425-5","url":null,"abstract":"<div><p>A novel Hg²⁺ sensing strategy has been developed based on a Mn-Au hybrid nanozyme with prominent oxidase-like activity and an aptamer-controlled catalytic switching mechanism. First, a Mn-Au hybrid nanozyme (MnAuNPs) with a distinctive “fried-egg-like” core–shell morphology was synthesized, which exhibited remarkable oxidase-like activity and rapidly oxidized 3,3’,5,5’-tetramethylbenzidine (TMB) into the characteristic blue product (OxTMB) without H₂O₂. The Hg²⁺-specific aptamer can adsorb onto the surface of MnAuNPs through electrostatic and Mn-phosphate coordination interactions, which blocks the catalytic sites and markedly suppresses the oxidase-like activity. In the presence of Hg²⁺, the specific T-Hg²⁺-T coordination triggers the detachment of the aptamer from the MnAuNPs surface, thereby restoring oxidase-like activity and inducing distinct color and absorbance change. Accordingly, an effective colorimetric platform for Hg²⁺ detection was developed, exhibiting a linear response over the range of 1.0–50 μM with a limit of detection (LOD) of 0.32 μM. In parallel, a paper-based smartphone-assisted sensing platform was developed, enabling on-site Hg²⁺ detection in the range of 5.0–50 μM with LOD of 5.0 μM. Through the colorimetric and smartphone-assisted method, accurate quantification of Hg²⁺ in the Yellow River water and wastewater samples were achieved with the results in good agreement with those obtained by ICP-OES. Overall, this work establishes a simple and portable H₂O₂-free colorimetric sensing strategy based on Hg²⁺-induced catalytic switching for environmental Hg²⁺ monitoring.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 11","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149098916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic sensitization between Rh-MOF and Ru(bpy)32+ driving superior electrochemiluminescence performance for selective L-proline detection","authors":"Tasneem Omda Edrees Isaa,&nbsp;Tadele Eticha,&nbsp;Solomon Sime Tessema,&nbsp;Saima Hanif,&nbsp;Jiyang Liu,&nbsp;Cunqi Wu,&nbsp;Guobao Xu","doi":"10.1007/s00604-026-08431-7","DOIUrl":"10.1007/s00604-026-08431-7","url":null,"abstract":"<div><p>A highly sensitive and cost-effective electrochemiluminescent (ECL) method has been developed for the selective detection of L-proline, addressing the growing demand for rapid small-molecule screening in health diagnostics. The method integrates a porous material, a rhodium-based metal–organic framework (Rh-MOF), synthesized via a rapid one-pot procedure involving coordination between Rh(III) ions and 2,4,6-tris(4-carboxyphenyl)-1,3,5-triazine (TCPrz), onto an isostatic graphite electrode (ISGE). Functioning as an efficient porous sensitizing host, Rh-MOF significantly amplified the anodic ECL signal of Ru(bpy)₃²⁺, resulting in a 93-fold enhancement. The method demonstrated excellent analytical performance, with a wide linear range (100 pM–1 mM), low detection limit (67 pM), and high selectivity toward L-proline. Analysis of real serum samples assured high recovery and good precision, highlighting the practical applicability of the proposed method in clinical diagnostics. This study offers novel perspectives on the development of MOFs as efficient enhancer, combined with the outstanding performance of low-cost ISGE, demonstrating promising applications in the detection of small biomolecules.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 11","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149098971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanoplastics in water and wastewater: remediation technologies, challenges, and future perspectives","authors":"Asiyeh Moteallemi,&nbsp;Mohammad Hadi Dehghani","doi":"10.1007/s00604-026-08440-6","DOIUrl":"10.1007/s00604-026-08440-6","url":null,"abstract":"<div><p>Nanoplastics (NPs) are emerging contaminants of increasing concern in aquatic environments because their small size, colloidal behavior, and surface reactivity complicate their detection and remediation. This review critically evaluates physical, physicochemical, biological, and hybrid technologies for NP remediation in water and wastewater, focusing on treatment mechanisms and endpoints, analytical evidence, matrix-dependent performance, practical applicability, and sustainability. An evidence-based treatment-endpoint framework is applied to distinguish capture/separation, aggregation followed by separation, fragmentation, degradation, and mineralization rather than comparing technologies solely on the basis of reported removal efficiencies. Current evidence indicates that membrane filtration, coagulation/flocculation, and adsorption can achieve substantial aqueous-phase removal under suitable conditions but predominantly transfer NPs to membranes, sludge, concentrates, or spent adsorbents rather than destroying the polymer. Advanced oxidation processes can promote polymer degradation and, under appropriate conditions, mineralization; however, their performance depends on reaction conditions, water-matrix characteristics, resource requirements, and the analytical evidence supporting the treatment endpoint. Biological approaches may offer lower-input alternatives but remain constrained by slow kinetics, polymer specificity, and limited evidence of extensive degradation. Hybrid systems can integrate particle capture and degradation, although their complexity may limit large-scale implementation. Major barriers include inconsistent treatment endpoints, incomplete NP mass balances, reliance on pristine particles and simplified matrices, analytical limitations, secondary-residual generation, and limited pilot-scale validation. Future research should prioritize real water matrices, environmentally relevant and aged NPs, complementary analytical methods, mass-balance verification, and systematic evaluation of energy demand, chemical consumption, residual management, cost, scalability, and life-cycle impacts to distinguish apparent removal from effective and sustainable remediation.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 11","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149098909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traffic-light-type visual sensing of bilirubin: a dual-emission Au-Ag NCs/MOF-808/Tb nanocomposite based on an asynchronous quenching strategy","authors":"Jian Gou,&nbsp;Xinlu He,&nbsp;Luxin Xing,&nbsp;Ning Bi,&nbsp;Jun Xu,&nbsp;Lina Zhang,&nbsp;Yongxin Li,&nbsp;Yuanyuan Huang,&nbsp;Lei Jia","doi":"10.1007/s00604-026-08428-2","DOIUrl":"10.1007/s00604-026-08428-2","url":null,"abstract":"<div><p>A dual-emission nanocomposite (Au-Ag NCs/MOF-808/Tb) was designed based on an asynchronous dual-quenching strategy. Gold-silver nanoclusters (Au-Ag NCs) with red fluorescence were modified on the surface of lanthanide-functionalized MOF-808, constructing a sensing system with traffic-light-like color transitions. Unlike the conventional ratiometric probes that rely on a stable internal reference, this system features two BR-responsive channels with different quenching rate (BR, bilirubin). Specifically, the green emission of Tb³⁺ at 545 nm showed a faster and more sensitive response toward BR, whereas the red emission of Au-Ag NCs at 650 nm changed more gently. On this basis, the 545 nm channel was selected as the primary analytical signal to establish the quantitative calibration curve, which afforded a limit of detection for BR as low as 44.24 nM.</p><p>The fluorescence intensity ratio I₅₄₅/I₆₅₀ was adopted to characterize the asynchronous response behavior of the dual-emission channels. Furthermore, by coupling the probe with a paper-based sensing platform and smartphone-assisted color analysis, visual and portable BR detection becomes possible with semi-quantitative concentration-range classification via a logic-gate scheme. By assembling multicomponent fluorescent materials with an asynchronous dual-response mechanism, this study demonstrates a new paradigm for the visual detection of biomarkers, and promotes the further development of portable analytical platforms.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 11","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149098064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-armed star-shaped PEG1000-encapsulated Mn2+:CsPbCl3 perovskite quantum dots for sensitive detection of crystal violet","authors":"Rongsheng Song,&nbsp;Die Su,&nbsp;Ya Deng,&nbsp;Dongxue Sun,&nbsp;Xia Xu,&nbsp;Bing Hu","doi":"10.1007/s00604-026-08442-4","DOIUrl":"10.1007/s00604-026-08442-4","url":null,"abstract":"<div><p>Mn²⁺-doped CsPbCl₃ quantum dots (Mn²⁺:CsPbCl₃ QDs) exhibit high photoluminescence quantum yields (PLQYs) and extended carrier diffusion lengths, but their use in aqueous environmental monitoring is hindered by poor water stability and fluorescence quenching. To address this challenge, a surface engineering strategy was employed in which the surfaces of Mn²⁺:CsPbCl₃ QDs were coated with star-shaped polyethylene glycol-1000 (PEG₁₀₀₀) ligands, it has significantly improved stability in aqueous solutions while maintaining optical performance. Taking into account the steric hindrance and surface passivation effects of multi-arm star-shaped PEG₁₀₀₀, the three-arm and four-arm star-shaped PEG₁₀₀₀ encapsulated Mn²⁺:CsPbCl₃ QDs exhibit good stability under weakly acidic conditions. Crystal Violet (CV) is an effective fluorescence quencher. Using the advantages of enhanced water stability of QDs and the fluorescence inner filter effect (IFE) between CV and QDs, a fluorescence detection platform was constructed. This platform enables quantitative detection of CV in aqueous solutions, achieving a detection limit of 1.136 µmol/L and a linear dynamic range of 0-23.78 µmol/L. This method presents a promising strategy for monitoring environmental pollutants and demonstrates distinct advantages in challenging aqueous matrices through the utilization of perovskite nanomaterials.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 11","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149098163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}