A rare multi-emission metal–organic complex fluorescent probe for direct oxytetracycline recognition

IF 5.3 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchimica Acta Pub Date : 2025-04-17 DOI:10.1007/s00604-025-07160-7

Zhaojing Yuan, Long Yu, Wenyuan Jiang, Xin Li, Zhiqing Wen, Xiangyang Hao, Mingtai Sun, Suhua Wang

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Abstract

A simple and effective metal–organic coordination polymer, EuIn@MOCPs, which enables the rapid and selective detection of oxytetracycline (OTC) among tetracycline antibiotics was successfully synthesized. Unlike the previously reported rare-earth-doped metal–organic complexes, this probe not only exhibits the common 617-nm characteristic peak in response to OTC but also uniquely generates uncommon peak shifts at 591 nm and 652 nm, allowing it to specifically recognize OTC among tetracycline antibiotics. We found that the response of the probe and OTC had a linear relationship with a detection limit as low as 42.3 nM within the 0–90-μM concentration range using multi-peak ratio fluorescence testing. Finally, the rich color change from blue to red in fluorescence makes this probe an excellent candidate for the development of high-performance visual fluorescent test strips. This achievement provides an effective approach for fluorescent probes to recognize structurally similar contaminants.

Graphical Abstract

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一种罕见的多发射金属-有机配合物荧光探针，用于直接识别土霉素

成功合成了一种简单有效的金属-有机配位聚合物EuIn@MOCPs，可快速、选择性地检测四环素类抗生素中的土霉素（OTC）。与之前报道的稀土掺杂金属有机配合物不同，该探针不仅在OTC响应中表现出常见的617 nm特征峰，而且在591 nm和652nm处独特地产生罕见的峰移，使其能够特异性识别四环素类抗生素中的OTC。通过多峰比荧光检测发现，在0 ~ 90 μ m浓度范围内，探针与OTC的响应呈线性关系，检出限低至42.3 nM。最后，在荧光中丰富的从蓝色到红色的颜色变化使该探针成为开发高性能视觉荧光试纸条的优秀候选者。这一成果为荧光探针识别结构相似的污染物提供了有效的方法。图形抽象

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来源期刊

Microchimica Acta 化学-分析化学

CiteScore

9.80

自引率

5.30%

发文量

410

审稿时长

2.7 months

期刊介绍： As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.