Microchimica Acta最新文献_第9页

Chiral nanoenzymes: synthesis and applications 手性纳米酶：合成与应用。

IF 5.3 2区化学

Microchimica Acta Pub Date : 2024-11-04 DOI: 10.1007/s00604-024-06803-5

Xiaohui Niu, Jianying Zhang, Mei Yuan, Yongqi Liu, Yuewei Wang, Hongxia Li, Kunjie Wang

{"title":"Chiral nanoenzymes: synthesis and applications","authors":"Xiaohui Niu, Jianying Zhang, Mei Yuan, Yongqi Liu, Yuewei Wang, Hongxia Li, Kunjie Wang","doi":"10.1007/s00604-024-06803-5","DOIUrl":"10.1007/s00604-024-06803-5","url":null,"abstract":"<div><p>Chiral nanoenzymes are a new type of material that possesses both chiral nanostructures and enzymatic catalytic activity. These materials exhibit selectivity in their catalytic activity towards organisms due to the introduction of chiral features in nanomaterials and have inherent chiral discrimination in organisms. As synthetic enzymes, chiral nanoenzymes offer significant advantages over natural enzymes. Due to their unique chiral structure and distinctive physicochemical properties, chiral nanoenzymes play an important role in various fields, including biology, medicine, and environmental protection. Their strong stereospecificity and biocompatibility make them useful in disease therapy, biosensing, and chiral catalysis, setting them apart from conventional and natural enzymes. In recent years, the design of synthetic methods and biological applications of chiral nanoenzymes has received significant attention and extensive research among scientists. This paper provides a systematic review of the research progress in the discovery, development, and application of chiral nanoenzymes in the last decade. Additionally, it presents various applications of chiral nanoenzymes, such as disease therapy, biosensing, and chiral catalysis. Finally, the challenges and future prospects of chiral nanoenzymes are discussed.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbon dot-based nanomaterials with enzyme-like activity for fluorescence imaging and potential combination with therapy of cancer 具有类似酶活性的碳点纳米材料，可用于荧光成像和潜在的癌症联合治疗。

IF 5.3 2区化学

Microchimica Acta Pub Date : 2024-11-04 DOI: 10.1007/s00604-024-06813-3

Juan Ning, Guojie Li, Yijun Zhao, Jiahui Shi, Yamin Nie, Yonghong Li, Yanmei Zhou

{"title":"Carbon dot-based nanomaterials with enzyme-like activity for fluorescence imaging and potential combination with therapy of cancer","authors":"Juan Ning, Guojie Li, Yijun Zhao, Jiahui Shi, Yamin Nie, Yonghong Li, Yanmei Zhou","doi":"10.1007/s00604-024-06813-3","DOIUrl":"10.1007/s00604-024-06813-3","url":null,"abstract":"<div><p>Carbon dot-based nanomaterials (o-CDs@Mn) were fabricated by assembling fluorescent o-CDs with enzyme-like activity and Mn nanoparticles with photothermal properties for realizing fluorescence imaging and combined therapy of cancer. Due to the inherent optical properties of o-CDs, o-CDs@Mn can be effectively used for bioimaging. In addition, o-CDs@Mn possess peroxidase-like (POD-like) and glutathione (GSH) degradation capabilities, which can effectively deplete excessive H<sub>2</sub>O<sub>2</sub> and GSH in the tumor microenvironment (TME), generating ·OH and reduced GSSH for regulating the TME and triggering ROS-mediated apoptosis in cancer cells. More importantly, it is synergistically supplemented with fluorescence imaging and photothermal therapy (PTT), which realizes the integration of monitoring and combined treatment, providing a promising potential pathway for accurate and efficient cancer treatment.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Graphene quantum dots modified electrodes as electrochemical sensing tool towards the detection of codeine in biological fluids and soft drinks 石墨烯量子点修饰电极作为电化学传感工具，用于检测生物液体和软饮料中的可待因。

IF 5.3 2区化学

Microchimica Acta Pub Date : 2024-11-04 DOI: 10.1007/s00604-024-06787-2

Lucía Ferrer-Biechy, M. Laura Soriano, Rafael Lucena, Soledad Cárdenas

{"title":"Graphene quantum dots modified electrodes as electrochemical sensing tool towards the detection of codeine in biological fluids and soft drinks","authors":"Lucía Ferrer-Biechy, M. Laura Soriano, Rafael Lucena, Soledad Cárdenas","doi":"10.1007/s00604-024-06787-2","DOIUrl":"10.1007/s00604-024-06787-2","url":null,"abstract":"<div><p>An electroanalytical method based on disposable screen-printed carbon electrodes modified with non-toxic carbonaceous nanodots is proposed as a reliable and effective device for codeine determination in biological fluids and soft drinks. Graphene quantum dots (GQDs), carbon quantum dots (CQDs) and carbon nanodots (CNDs) were evaluated as electrode modifiers for the determination of the drug. The electroactive areas of the modified electrodes were assessed by cyclic voltammetry using potassium ferricyanide. Results demonstrated that GQDs provided the best analytical response for codeine, displaying an intense and well-defined anodic wave approximately 0.9 V vs reference electrode. The method exhibits an acceptable linear dynamic range, low limits of detection and quantification (0.21 and 0.73 µM, respectively), and satisfactory precision (below 3.9% expressed as relative standard deviation (RSD)) in saliva. Only the analysis of biofluids requires a simple extraction protocol. The feasibility and applicability of this novel approach were assessed by determining codeine in different matrices, with recoveries ranging from 69 to 112%. This cost-effective, simple, easily miniaturised and portable method was applied not only to biofluids but also for the direct detection of codeine in soft drinks combined with a codeine-enriched syrup, a medication that is being used to adulterate beverages, particularly at specific events (drinking and nightclub parties). There is no need for any sample treatment, demonstrating its versatility in analysing beverages for potential adulteration as well.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An inverted tetrahedron-mediated DNA walker for sulfadimethoxine detection 用于磺胺二甲氧嗪检测的倒四面体介导 DNA 步行器。

IF 5.3 2区化学

Microchimica Acta Pub Date : 2024-11-04 DOI: 10.1007/s00604-024-06810-6

Tai Ye, Zheng Luo, Yueyue Che, Min Yuan, Hui Cao, Liling Hao, Qian Zhang, Yongxin Xie, Kaisen Zhang, Fei Xu

{"title":"An inverted tetrahedron-mediated DNA walker for sulfadimethoxine detection","authors":"Tai Ye, Zheng Luo, Yueyue Che, Min Yuan, Hui Cao, Liling Hao, Qian Zhang, Yongxin Xie, Kaisen Zhang, Fei Xu","doi":"10.1007/s00604-024-06810-6","DOIUrl":"10.1007/s00604-024-06810-6","url":null,"abstract":"<div><p> An inverted DNA tetrahedron–mediated modular DNA walker was developed for the determination of sulfadimethoxine. The inverted DNA tetrahedron scaffold raises several advantages of recognition module including appropriate lateral space, multiple recognition domains, and cost-effectiveness. The proposed inverted DNA tetrahedron-based recognition module exhibited better binding affinity and kinetics toward target antibiotic than that of other DNA tetrahedron counterparts. Upon specific binding with target, the released bipedal DNA walking strand hops to the signal amplification module and moves stochastically with assistant of nicking enzyme. By coupling these two modules, a good linear relationship between the fluorescence intensity of supernatant and the concentration of sulfadimethoxine was achieved in the range 0.1–100 nM, and the limit of detection was 64.7 pM. Furthermore, this modular DNA walker had also successfully applied to spiked honey and milk samples with satisfactory recoveries from 91.5 to 108.8%, demonstrating its practical sensing capability.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 12","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142574832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-mode electrochemical and electrochemiluminescence detection of dopamine based on perylene diimide self-assembly material 基于过二亚胺自组装材料的多巴胺双模电化学和电化学发光检测技术

IF 5.3 2区化学

Microchimica Acta Pub Date : 2024-10-31 DOI: 10.1007/s00604-024-06768-5

Wei Zhang, Hong Zhang, Chuan Li, Lei Shang, Rongna Ma, Liping Jia, Xiaojian Li, Bo Li, Huaisheng Wang

{"title":"Dual-mode electrochemical and electrochemiluminescence detection of dopamine based on perylene diimide self-assembly material","authors":"Wei Zhang, Hong Zhang, Chuan Li, Lei Shang, Rongna Ma, Liping Jia, Xiaojian Li, Bo Li, Huaisheng Wang","doi":"10.1007/s00604-024-06768-5","DOIUrl":"10.1007/s00604-024-06768-5","url":null,"abstract":"<div><p>The self-assembly material N,N-bis-(3-dimethyl aminopropyl)-3,4,9,10-perylene tetracarboxylic acid diimide (PDI) is reported to show electrochemical (EC)/electrochemiluminescence (ECL) property for designing new dual-mode dopamine (DA) sensors. K<sub>2</sub>S<sub>2</sub>O<sub>8</sub> significantly improved the EC reduction current at -0.346 V and ECL intensity at -0.25 V of the PDI self-assembly material. DA largely decreased the EC reduction current and ECL intensity of this homogeneous EC/ECL material due to the competitive consumption of K<sub>2</sub>S<sub>2</sub>O<sub>8</sub> in the oxidization process of DA and the low electron conductivity of polyDA formed through the oxidization of DA by K<sub>2</sub>S<sub>2</sub>O<sub>8</sub>. In addition, the ECL quenching mechanism involved an energy-transfer process resulting from the collision between the produced o-benzoquinone species (oxidization of DA) and the excited state of PDI, which decreased the ECL intensity. This homogeneous EC/ECL material showed linear EC current response for DA from 5.0 nM to 50.0 µM with a detection of limit of 2.7 nM and linear ECL response for DA from 1.0 nM to 100.0 µM with a detection of limit of 0.41 nM. The proposed dual-mode EC/ECL sensors also showed good feasibility in urine sample analysis.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142555233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A novel molecularly imprinted electrochemical sensor based on quasi-three-dimensional nanomaterials Nb2CTx/AgNWs for specific detection of sulfadiazine 基于准三维纳米材料 Nb2CTx/AgNWs 的新型分子印迹电化学传感器用于磺胺嘧啶的特异性检测

IF 5.3 2区化学

Microchimica Acta Pub Date : 2024-10-31 DOI: 10.1007/s00604-024-06805-3

Yifei Wang, Jingwen He, Jie Wu, Wen Hao, Lin Cai, Haiyang Wang, Guozhen Fang, Shuo Wang

{"title":"A novel molecularly imprinted electrochemical sensor based on quasi-three-dimensional nanomaterials Nb2CTx/AgNWs for specific detection of sulfadiazine","authors":"Yifei Wang, Jingwen He, Jie Wu, Wen Hao, Lin Cai, Haiyang Wang, Guozhen Fang, Shuo Wang","doi":"10.1007/s00604-024-06805-3","DOIUrl":"10.1007/s00604-024-06805-3","url":null,"abstract":"<div><p>A novel molecularly imprinted electrochemical sensor (MIECS) was constructed for the specific detection of sulfadiazine (SDZ) in food. Niobium carbide (Nb<sub>2</sub>CTx) as a typical two-dimensional lamellar nanomaterial has good electrical conductivity and unique structure, which was assembled with one-dimensional silver nanowires (AgNWs) to form quasi-three-dimensional composite nanomaterials (Nb<sub>2</sub>CTx/AgNWs). As spacer material, AgNWs prevented the aggregation of Nb<sub>2</sub>CTx and the collapse of Nb<sub>2</sub>CTx layers. At the same time, a fast electron transport channel was constructed through the synergistic effect between nanomaterials the two. The Nb<sub>2</sub>CTx/AgNWs realized the enhancement of electrical signals. Molecularly imprinted polymers (MIPs) endowed the sensor with selectivity, achieving the specific detection of sulfadiazine. Under the optimal experimental conditions, the method has a wide linear range (1 × 10<sup>−8</sup>–1 × 10<sup>−4</sup> mol L<sup>−1</sup>) and a low limit of detection (1.30 × 10<sup>−9</sup> mol L<sup>−1</sup>). The sensor was used to detect sulfadiazine in pork, chicken, and feed samples, and the recovery was 82.61–94.87%. The results were in good agreement with the HPLC results, which proved the accuracy and practicability of the method.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142555232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A cotton swab platform for fluorescent detection of aluminum ion in food samples based on aggregation-induced emission of carbon dots 基于碳点聚集诱导发射的食品样品铝离子荧光检测棉签平台

IF 5.3 2区化学

Microchimica Acta Pub Date : 2024-10-30 DOI: 10.1007/s00604-024-06799-y

Tong Shao, Dou Yang, Xiaoshuang Wang, Ruirui Wang, Qiaoli Yue

{"title":"A cotton swab platform for fluorescent detection of aluminum ion in food samples based on aggregation-induced emission of carbon dots","authors":"Tong Shao, Dou Yang, Xiaoshuang Wang, Ruirui Wang, Qiaoli Yue","doi":"10.1007/s00604-024-06799-y","DOIUrl":"10.1007/s00604-024-06799-y","url":null,"abstract":"<div><p>A novel portable cotton swab based on nitrogen-doped carbon dots (NCDs) for Al<sup>3+</sup> detection was constructed for the first time. NCDs with bright green fluorescence were prepared by hydrothermal method with phenylhydrazine hydrochloride and 3-hydroxy-2-naphthoic acid hydrazide as precursors. The surface of NCDs was exposed to abundant functional groups (such as amino, carboxyl, hydroxyl, etc.), which was helpful for the formation of complexes between NCDs and Al<sup>3+</sup>. In the presence of Al<sup>3+</sup>, the aggregation of NCDs obviously induced their fluorescence enhancement due to the aggregation-induced emission (AIE) of NCDs. Furthermore, the quantum yield (QY) of NCDs was enhanced by 12 times with Al<sup>3+</sup>, and the fluorescence lifetime was increased by 7.54 ns. The fluorescence intensity was linearly correlated with the concentration of Al<sup>3+</sup> (2.5–300 μM), and the limit of detection was 0.76 μM. Moreover, for the portable way, cotton swabs were successfully employed to construct the sensors for the detection of Al<sup>3+</sup> in food samples. This proposal has potential for the application in food analysis.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low-cost portable sensor for rapid and sensitive detection of Pb2+ ions using capacitance sensing integrated with microfluidic enrichment 利用集成微流控富集技术的电容传感技术，快速灵敏地检测 Pb2+ 离子的低成本便携式传感器。

IF 5.3 2区化学

Microchimica Acta Pub Date : 2024-10-30 DOI: 10.1007/s00604-024-06798-z

Niloufar Amin, Jiangang Chen, Qing Cao, Haochen Qi, Jian Zhang, Qiang He, Jie Jayne Wu

{"title":"Low-cost portable sensor for rapid and sensitive detection of Pb2+ ions using capacitance sensing integrated with microfluidic enrichment","authors":"Niloufar Amin, Jiangang Chen, Qing Cao, Haochen Qi, Jian Zhang, Qiang He, Jie Jayne Wu","doi":"10.1007/s00604-024-06798-z","DOIUrl":"10.1007/s00604-024-06798-z","url":null,"abstract":"<div><p>Lead ion (Pb<sup>2+</sup>) pollution is a critical global issue due to its ability to accumulate in the human body, resulting in severe health problems. Despite extensive research efforts devoted to the detection of Pb<sup>2+</sup> contamination, practical, rapid, and field-deployable sensors for Pb<sup>2+</sup> is yet to be developed to effectively safeguard the environment and public health. Herein, a label-free affinity-based sensing device is developed based on printed circuit board (PCB) for low-cost, easy-to-use, and real-time on-site detection of Pb<sup>2+</sup> ions. The sensors are prepared by forming a self-assembled monolayer of glutathione (GSH) on the surface of gold-plated PCB electrodes, which serves as a molecular probe to recognize Pb<sup>2+</sup>. Rapid and sensitive detection is achieved by using capacitance sensing integrated with microfluidic enrichment. The sensor’s interfacial capacitance is used to indicate specific binding, while the capacitance reading process simultaneously induces alternating current electrothermal (ACET) acceleration of analyte’s travel towards the probes. Thus, the enrichment and detection are integrated into a single step, making pre-concentration unnecessary and shortening the assay time to 30 s. This Pb<sup>2+</sup> sensor has demonstrated one of the lowest limits of detection reported so far (1.85 fM) with a linear range of 0.01–10 pM. To evaluate the sensor’s specificity, non-target metal ions are tested, all showing negligible responses. Testing of tap water sample also yields reasonable results, validating the sensor’s robustness. The above-mentioned features, together with a commercial portable readout, make this sensor well-suited for point-of-use Pb<sup>2+</sup> detection at low cost.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142542811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Uniform PtCoRuRhFe high-entropy alloy nanoflowers: Multi-site synergistic signal amplification for colorimetric assay of captopril 均匀的 PtCoRuRhFe 高熵合金纳米花：卡托普利比色测定的多位点协同信号放大。

IF 5.3 2区化学

Microchimica Acta Pub Date : 2024-10-30 DOI: 10.1007/s00604-024-06746-x

Rui Zhang, Jia-Qi Li, Ai-Jun Wang, Pei Song, Wen Liu, Jiu-Ju Feng, Tuck Yun Cheang

{"title":"Uniform PtCoRuRhFe high-entropy alloy nanoflowers: Multi-site synergistic signal amplification for colorimetric assay of captopril","authors":"Rui Zhang, Jia-Qi Li, Ai-Jun Wang, Pei Song, Wen Liu, Jiu-Ju Feng, Tuck Yun Cheang","doi":"10.1007/s00604-024-06746-x","DOIUrl":"10.1007/s00604-024-06746-x","url":null,"abstract":"<div><p>Uniform PtCoRuRhFe high-entropy alloy nanoflowers (HEANFs) were fabricated by a simple wet-chemical co-reduction method in oleylamine for quantitative colorimetric determination of captopril (CAP) based on multi-site synergistic signal amplification. Specifically, the peroxidase mimetic activity of the PtCoRuRhFe HEANFs was examined through catalysis of 3,3′,5,5′-tetramethylbenzidine (TMB) oxidation, whose catalytic mechanism was investigated by electron paramagnetic resonance (EPR) spectroscopy. The role of the ·O<sub>2</sub><sup>−</sup> was figured out during the catalytic procedure. Further, the oxidation of TMB (oxTMB) can be effectively reduced by CAP, accompanied by quickly transforming the solution color from blue to colorless. More importantly, the absorbance at 652 nm is linearly related to the CAP concentration in a range 5.0–50.0 mM with a low detection limit of 2.82 mM. The method has been applied to the determination of CAP in human urine samples. It offers a simple and high-efficiency method for facile and visual detection of CAP in hospitals.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142542812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploration of cucurbituril-mediated SERS plasmonic nanoarrays with sub-nanometer gaps 探索葫芦素介导的具有亚纳米间隙的 SERS 等离子纳米阵列。

IF 5.3 2区化学

Microchimica Acta Pub Date : 2024-10-30 DOI: 10.1007/s00604-024-06800-8

Yuanjie Teng, Xin Li, Yingxin Chen, Yi Zhong, Pei Xu, Shengyan Shan, Sundaram Gunasekaran

{"title":"Exploration of cucurbituril-mediated SERS plasmonic nanoarrays with sub-nanometer gaps","authors":"Yuanjie Teng, Xin Li, Yingxin Chen, Yi Zhong, Pei Xu, Shengyan Shan, Sundaram Gunasekaran","doi":"10.1007/s00604-024-06800-8","DOIUrl":"10.1007/s00604-024-06800-8","url":null,"abstract":"<div><p>The uneven distribution of hotspots and the challenges associated with precise analyte localization within these hotspots present significant hurdles in the field of surface-enhanced Raman scattering (SERS). Here, at the water–oil interface, gold nanoparticles (AuNPs) interconnected by cucurbiturils[8] (CB[8]) with sub-nanometer gaps (AuNPs:CB[8]) were organized into plasmonic arrays. This arrangement was engineered to generate highly efficient hotspots. The CB[8] molecules, serving a dual role, not only facilitated the assembly of AuNPs with sub-nanometer (~ 1 nm) gaps to create intense plasmonic hotspots but also acted as molecular traps, enabling the precise localization of molecules within these hotspots. By comparing the enhancement effect of probe molecule on Au nanofilm, AuNPs:CB[8] colloids, and AuNPs:CB[8] nanofilm, it was found that the SERS intensity of the E1 characteristic peak in AuNPs:CB[8] nanofilm is five times higher than that on Au nanofilm, and more than 10<sup>4</sup> times higher than that of AuNPs:CB[8] colloids. The gaps are also accessible to different electronegativite molecules, such as estrone, <i>p</i>-aminoazobenzene, or methylene blue, which are captured at the plasmonic hotspots by the interaction of CB[8]. The method was employed for the practical detection of artificial antioxidant butylated hydroxyanisole (BHA), which has a weak Raman scattering cross-section, by coupling it with a reaction to enhance its SERS effect. The detection limit of BHA in soybean oil sample is 5.89 × 10<sup>−8</sup> mol/L, with the recovery range 85.1–115%. In conclusion, this hot-spot design and molecular capture approach will offer a highly effective method for detecting weak Raman scattering cross-section molecules and holds great promise for practical applications in the future.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"191 11","pages":""},"PeriodicalIF":5.3,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142542810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0