Microchimica Acta最新文献_第9页

Facile synthesis of long-wavelength fluorescent carbon dots: toward multifunctional applications in nitrite sensing and bioimaging 长波长荧光碳点的简易合成：在亚硝酸盐传感和生物成像中的多功能应用。

IF 5.4 2区化学

Microchimica Acta Pub Date : 2026-09-07 DOI: 10.1007/s00604-026-08386-9

Xia Bian, Zhefeng Fan

引用次数: 0

Harnessing charge transfer to enhance peroxidase-like activity of Au@Pt nanozyme for assessing total antioxidant capacity 利用电荷转移增强Au@Pt纳米酶的过氧化物酶样活性以评估总抗氧化能力。

IF 5.4 2区化学

Microchimica Acta Pub Date : 2026-09-07 DOI: 10.1007/s00604-026-08391-y

Phouphien Keoingthong, Yanhong Li, Yu Zhang, Bounmany Thipthilarth, Vanseng Chounlamany, Bounnam Xomvimane, Chanhphone Vongkhampheng, Oulay Phoupasong, Shi-Gang Liu, Shengkai Li

{"title":"Harnessing charge transfer to enhance peroxidase-like activity of Au@Pt nanozyme for assessing total antioxidant capacity","authors":"Phouphien Keoingthong, Yanhong Li, Yu Zhang, Bounmany Thipthilarth, Vanseng Chounlamany, Bounnam Xomvimane, Chanhphone Vongkhampheng, Oulay Phoupasong, Shi-Gang Liu, Shengkai Li","doi":"10.1007/s00604-026-08391-y","DOIUrl":"10.1007/s00604-026-08391-y","url":null,"abstract":"<div><p>Reliable total antioxidant capacity (TAC) detection in foods is of considerable practical importance for evidence-based dietary guidance and disease prevention. We designed a core-shell Au@Pt nanozyme with enhanced peroxidase (POD)-like activity, driven by electron transfer from the Au core to the Pt shell. This interfacial charge modulation lowers the catalytic energy barrier, as confirmed by structural characteristic characterization and density functional theory (DFT) calculations. The Au@Pt nanozyme also exhibits excellent long-term stability and low batch-to-batch variation. Leveraging these advantages, we developed a sensitive colorimetric platform for ascorbic acid detection, in which Au@Pt serves as the signal transducer and 3,3′,5,5′-tetramethylbenzydine (TMB) as the chromogenic substrate. The assay relies on the ability of AA to quench reactive oxygen species and reduce oxidized TMB. This platform exhibits high selectivity, with negligible interference from common ions, small biomolecules, or other antioxidants. We further validated the method by determining total antioxidant capacity in commercial vitamin C tablets, beverages, and fresh fruit juices, with results expressed as mg AA equivalent per liter. The values obtained were consistent with those from the standard cupric reducing antioxidant capacity (CUPRAC) method. This work presents a rational nanozyme design <i>via</i> interfacial engineering and offers a practical tool for antioxidant assessment in complex food matrices.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 10","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A ultrasensitive immunoassay based on weakly charged AuNPs orientated antibody for triazophos detection in vegetables 基于弱电荷AuNPs定向抗体的超灵敏蔬菜三唑磷检测方法。

IF 5.4 2区化学

Microchimica Acta Pub Date : 2026-09-07 DOI: 10.1007/s00604-026-08384-x

Qinghuan Wu, Qijun Wang, A.M. Abd El-Aty, Xing Zhang, Guangyang Liu, Hui Li, Xinyan Liu, Lin Qin, Xiaodong Huang, Donghui Xu, Ge Chen

{"title":"A ultrasensitive immunoassay based on weakly charged AuNPs orientated antibody for triazophos detection in vegetables","authors":"Qinghuan Wu, Qijun Wang, A.M. Abd El-Aty, Xing Zhang, Guangyang Liu, Hui Li, Xinyan Liu, Lin Qin, Xiaodong Huang, Donghui Xu, Ge Chen","doi":"10.1007/s00604-026-08384-x","DOIUrl":"10.1007/s00604-026-08384-x","url":null,"abstract":"<div><p>Immunoassays based on gold nanoparticles (AuNPs) often suffer from limited sensitivity. Herein, we synthesized weakly charged AuNPs using ascorbic acid and establish a competitive immunoassay for the detection of triazophos. The weak electronegativity of these AuNPs reduces electrostatic repulsion during antibody adsorption, leading to increased antibody loading and favorable antibody orientation, thereby enhancing detection sensitivity. The triazophos antibody and horseradish peroxidase (HRP) were electrostatically adsorbed onto the AuNP surface to form an antibody-AuNP-enzyme probe complex. In the immunoassay, triazophos in the sample competes with the coated antigen for binding to the Ab@AuNPs@HRP probe, and quantification is achieved through an HRP-catalyzed colorimetric reaction. The proposed method demonstrated a linear range of 1.08–22.48 µg/L, an IC<sub>50</sub> value of 4.93 µg/L, and a detection limit as low as 0.06 µg/L. This approach eliminates the need for enzyme-labeled secondary antibodies, offering advantages such as lower cost, simpler operation, higher sensitivity, and good specificity.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 10","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Copper-modified peanut shell biochar-based electrochemical sensor for the detection of glufosinate ammonium in food and environmental samples 铜修饰花生壳生物炭基电化学传感器检测食品和环境样品中草铵膦铵。

IF 5.4 2区化学

Microchimica Acta Pub Date : 2026-09-07 DOI: 10.1007/s00604-026-08382-z

Xun Gong, Yingying Li, Jie Hu, Xingchen Yao, Ya Wang, Xiupei Yang

{"title":"Copper-modified peanut shell biochar-based electrochemical sensor for the detection of glufosinate ammonium in food and environmental samples","authors":"Xun Gong, Yingying Li, Jie Hu, Xingchen Yao, Ya Wang, Xiupei Yang","doi":"10.1007/s00604-026-08382-z","DOIUrl":"10.1007/s00604-026-08382-z","url":null,"abstract":"<div><p>A novel electrochemical sensing platform was developed using copper-modified and alkali-activated peanut shell biochar (CuPS-OH) for the selective and sensitive detection of glufosinate ammonium (GLA) in food and environmental samples. The sensor operates on the basis of solid-state electrochemical signal amplification from in situ-formed CuCl, which is generated via the reaction between surface Cu species and Cl⁻. GLA specifically binds to copper active sites and competitively suppresses the CuCl signal, enabling quantitative detection. Material characterization confirmed that alkaline treatment significantly improved the conductivity and electroactive surface area of the biochar composite. Under optimized conditions, the sensor exhibited a wide linear range of 0.2–200 µM and a low detection limit of 58 nM. It demonstrated outstanding anti-interference capability, stability, and accuracy in real-sample analyses (grape, river water, and soil), with recoveries ranging from 96.0% to 103.6%. This work offers a feasible and efficient strategy for developing high-performance biochar-based electrochemical sensors applicable to food safety and environmental monitoring.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 10","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Machine learning-assisted colorimetric serum phosphate detection based on sweet potato-derived carbon dots 基于红薯衍生碳点的机器学习辅助比色血清磷酸盐检测。

IF 5.4 2区化学

Microchimica Acta Pub Date : 2026-09-05 DOI: 10.1007/s00604-026-08388-7

Liu Chao, Ren Wang, Yan Lin, Zhonghai Zhang, Qinghe Cao, Ziqi Tao, Conghui Han, Guiye Shan, Jun Tian

{"title":"Machine learning-assisted colorimetric serum phosphate detection based on sweet potato-derived carbon dots","authors":"Liu Chao, Ren Wang, Yan Lin, Zhonghai Zhang, Qinghe Cao, Ziqi Tao, Conghui Han, Guiye Shan, Jun Tian","doi":"10.1007/s00604-026-08388-7","DOIUrl":"10.1007/s00604-026-08388-7","url":null,"abstract":"<div><p>A dual-robust, portable colorimetric sensing platform was developed by integrating purple sweet potato-derived carbon dots (PF-CDs) with machine learning-assisted signal processing. Serving as a highly stable, green nano-reductant, the PF-CDs effectively circumvent the autoxidation issues of conventional reagents, efficiently triggering the molybdenum blue reaction to produce a reliable macroscopic colorimetric response. To decouple these signals from environmental and matrix noise, a smartphone-based imaging system coupled with an machine learning algorithm was deployed for precise color recognition and automated quantitative determination. This integrated platform enables rapid phosphate detection within 60 min, exhibiting a broad linear range of 0.1-5.0 mM, a low limit of detection (LOD) of 0.03 mM, and an exceptional prediction accuracy of 99%. Ultimately, by synergizing chemical stability with analytical precision, this strategy offers a highly practical, low-cost, and robust paradigm for POC clinical phosphorus monitoring.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 10","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research progress on nanoplatforms for in vivo miRNA detection over the past decade 近十年来体内miRNA检测纳米平台的研究进展。

IF 5.4 2区化学

Microchimica Acta Pub Date : 2026-09-05 DOI: 10.1007/s00604-026-08383-y

Yifang Jin, Jie Zhou

引用次数: 0

Ru-N coordination hydrogen-bonded organic frameworks with enhanced peroxidase-like activity for colorimetric determination of gastric cancer-related salivary D-amino acids 具有增强过氧化物酶样活性的Ru-N配位氢键有机框架用于胃癌相关唾液d -氨基酸的比色测定。

IF 5.4 2区化学

Microchimica Acta Pub Date : 2026-09-05 DOI: 10.1007/s00604-026-08392-x

Haiting Liang, Qi Jiao, Jinghan Wu, Xiujuan Chen, Qi Liang, Li Hou, Shulin Zhao, Tianran Lin

{"title":"Ru-N coordination hydrogen-bonded organic frameworks with enhanced peroxidase-like activity for colorimetric determination of gastric cancer-related salivary D-amino acids","authors":"Haiting Liang, Qi Jiao, Jinghan Wu, Xiujuan Chen, Qi Liang, Li Hou, Shulin Zhao, Tianran Lin","doi":"10.1007/s00604-026-08392-x","DOIUrl":"10.1007/s00604-026-08392-x","url":null,"abstract":"<div><p>Hydrogen-bonded organic frameworks (HOFs) are promising porous crystalline materials for sensing, but their weak intrinsic enzyme-like activity limits nanozyme applications. Herein, a Ru-functionalized HOF material (Ru-HOFs) was fabricated through Ru–N coordination. In this material, the HOFs framework anchors and stabilizes the Ru sites. The resulting Ru-HOFs exhibited enhanced peroxidase-like activity toward hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-mediated oxidation of o-phenylenediamine (OPD), with favorable catalytic stability and substrate affinity. Density functional theory (DFT) calculations suggest that Ru-N coordination modulates the local electronic structure and provides a more favorable free-energy profile for H<sub>2</sub>O<sub>2</sub> adsorption and subsequent activation. By coupling Ru-HOFs with D-amino acid oxidase (DAAO), a cascade colorimetric platform was developed for salivary D-proline (D-Pro) and D-alanine (D-Ala), two reported gastric cancer (GC)-related D-amino acids (DAAs). Under individual assay conditions, the platform showed linear ranges of 2–150 µmol L⁻¹ for D-Pro and 5–100 µmol L⁻¹ for D-Ala, with limits of detection of 0.6112 and 2.299 µmol L⁻¹, respectively. Smartphone-based red–green–blue (RGB) analysis enabled visual readout and quantitative determination under controlled conditions. Spiked saliva tests showed satisfactory recoveries, demonstrating the applicability of the proposed assay to saliva matrices for the analysis of reported GC-related salivary DAAs. This work also provides a useful strategy for constructing coordination-regulated HOF-based nanozymes with improved catalytic performance for colorimetric sensing applications.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 10","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrasonic spray pyrolysis and electro-nanofabrication of carbon-gold-based biosensor for circulating tumor cell detection 循环肿瘤细胞检测用碳金基生物传感器的超声喷雾热解与电纳米制作。

IF 5.4 2区化学

Microchimica Acta Pub Date : 2026-09-05 DOI: 10.1007/s00604-026-08377-w

Zahra Khadivi Khanghah, Hadi Hashemzadeh, Saeed Rahemi Ardekani, Esmaiel Saievar-Iranizad, Hossein Naderi-Manesh

{"title":"Ultrasonic spray pyrolysis and electro-nanofabrication of carbon-gold-based biosensor for circulating tumor cell detection","authors":"Zahra Khadivi Khanghah, Hadi Hashemzadeh, Saeed Rahemi Ardekani, Esmaiel Saievar-Iranizad, Hossein Naderi-Manesh","doi":"10.1007/s00604-026-08377-w","DOIUrl":"10.1007/s00604-026-08377-w","url":null,"abstract":"<div><p>The development of an ultrasensitive electrochemical biosensor for the label-free detection of HER2-positive breast cancer cells is reported. The developed platform leverages a novel hierarchical nanoarchitecture to achieve superior analytical performance. The nanofabricated system was constructed by depositing a carbon-gold nanoparticle (C-AuNP) layer on a fluorine-doped tin oxide (FTO) electrode via ultrasonic spray pyrolysis, in the first step. The process was followed by the electrochemical growth of gold nanostructures (AuNS) to form a conductive C-AuNP@AuNS nanocomposite. This tailored nanofabrication, dramatically enhanced the electrode’s conductivity and provided an optimal substrate for bioreceptor immobilization. The surface was functionalized with Herceptin antibody for specific cell capture. Quantitative performance was evaluated using electrochemical impedance spectroscopy (EIS) and differential pulse voltammetry (DPV). The biosensor demonstrated a wide linear response from 2.5 × 10<sup>2</sup> to 1 × 10<sup>4</sup> cells mL⁻¹, an exceptionally low limit of detection (LOD) of 2 cells mL⁻¹, and high specificity against HER2-negative MCF7 cells, confirming minimal non-specific adsorption. The sensor’s robustness was validated by its stable biorecognition layer, which retained functionality for over three months. This work advances the field by integrating a scalable spray pyrolysis step with precise electrochemical nanostructuring to create a high-performance interface. The achieved metrics, combining an ultra-low LOD, and operational stability in complex media, represent a significant improvement over existing HER2 cell sensors. In addition, these results underscore the platform’s strong potential for translation into early, point-of-care cancer diagnostics.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 10","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multifunctional cardiac tropin I sensing using MWCNTs-COOH/PoPD composites for integrated warning, screening and protection assessment of traditional Chinese medicine-induced cardiotoxicity MWCNTs-COOH/PoPD复合材料多功能心脏tropin I检测在中药致心脏毒性综合预警、筛选和保护评价中的应用

IF 5.4 2区化学

Microchimica Acta Pub Date : 2026-09-05 DOI: 10.1007/s00604-026-08376-x

Xuanxiu Da, Yaru Zhang, Peng Jin, Bolu Sun, Chengwen Li, Miao Zhou, Haiying He, Jiali Kang, Chenyu Qin, Jiaru Fu, Yuxin Dong, Lin Yang

{"title":"Multifunctional cardiac tropin I sensing using MWCNTs-COOH/PoPD composites for integrated warning, screening and protection assessment of traditional Chinese medicine-induced cardiotoxicity","authors":"Xuanxiu Da, Yaru Zhang, Peng Jin, Bolu Sun, Chengwen Li, Miao Zhou, Haiying He, Jiali Kang, Chenyu Qin, Jiaru Fu, Yuxin Dong, Lin Yang","doi":"10.1007/s00604-026-08376-x","DOIUrl":"10.1007/s00604-026-08376-x","url":null,"abstract":"<div><p>Cardiac troponin I (cTnI), the most sensitive and specific biomarker of myocardial injury, enables early detection of subclinical cardiotoxicity. Highly sensitive cTnI testing is therefore crucial for early safety assessment of TCM. This study developed an electrochemical immunosensor for cTnI using a carboxylated multi-walled carbon nanotube/poly(o-phenylenediamine) (MWCNTs-COOH/PoPD) composite sensing membrane. This design leverages the large surface area and high conductivity of MWCNTs-COOH along with PoPD’s biocompatibility to enhance electrochemical performance. Antibodies achieved controllable covalent immobilization with preferential orientation via 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide/N-hydroxysuccinimide (EDC/NHS) cross-linking, facilitating specific recognition of cTnI. Under optimized conditions, the sensor exhibited excellent linearity across the ranges of 0.2–40 pg/mL and 0.05–50 ng/mL, with detection limits of 0.06 pg/mL and 4.17 pg/mL, respectively, demonstrating high sensitivity, specificity, and stability. Successfully applied to screen cardiotoxic TCM components, the sensor accurately detected cTnI released from cardiomyocytes, enabling precise quantification of toxins such as aconitine. It was also extended to evaluate myocardial protectants such as baicalin and their synergistic detoxification effects. This work establishes an efficient, sensitive platform for early TCM cardiotoxicity warning and toxic substance identification based on cTnI, while also supporting the screening of protective components. It is crucial for safeguarding the clinical safety of TCM and fostering the sustainable development of its industry.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 10","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-form iron on carbon nanohorns for wide-pH-range electrochemical sensing of levodopa 碳纳米角上双形态铁用于左旋多巴的宽ph范围电化学传感。

IF 5.4 2区化学

Microchimica Acta Pub Date : 2026-09-05 DOI: 10.1007/s00604-026-08313-y

Yun Zhou, Yang Yu, Jia Zhang, Yali Yang, Yamei Luo, Ruixia Gao, Kezhi Liu, Wei Dong

{"title":"Dual-form iron on carbon nanohorns for wide-pH-range electrochemical sensing of levodopa","authors":"Yun Zhou, Yang Yu, Jia Zhang, Yali Yang, Yamei Luo, Ruixia Gao, Kezhi Liu, Wei Dong","doi":"10.1007/s00604-026-08313-y","DOIUrl":"10.1007/s00604-026-08313-y","url":null,"abstract":"<div><p>Levodopa is a first-line therapeutic agent for Parkinson’s disease, and real-time monitoring of its plasma concentration is crucial for optimizing personalized treatment strategies. In this study, iron/carbon nanohorn composites (Fe/CNHs(2)) featuring a dual-form Fe structure, in which atomically or sub-nanocluster dispersed Fe species coexist with Fe nanoparticles, were synthesized via a one-step positive-pressure arc-discharge method. The fabricated Fe/CNHs(2)-based sensing electrode exhibited excellent electrocatalytic activity toward levodopa, achieving a high sensitivity of 0.062 µA µM⁻¹ and a low detection limit of 0.75 µM. Moreover, the sensor enabled stable levodopa detection over a broad pH range of 3.6–9.5. Kinetic studies revealed that the wide pH tolerance originated from the enhanced structural stability provided by strong Fe–C interfacial interactions, together with an adsorption-controlled reaction process in which the rate-determining step showed limited dependence on proton concentration. Theoretical calculations further confirmed that the introduction of Fe active centers substantially decreased the reaction energy barrier. This work provides a new design strategy for metal–carbon composites with dual-functional synergy, and the developed sensor holds considerable potential for monitoring levodopa levels during Parkinson’s disease treatment.</p><h3>Graphical abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"193 10","pages":""},"PeriodicalIF":5.4,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148896284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0