Chou-Yi Hsu, Prakash Kanjariya, I. A. Ariffin, Asha Rajiv, Aditya Kashyap, G. D. Anbarasi Jebaselvi, Satish Choudhury, Yashpal Yadav, P. Sankara Rao, Sanjeev Kumar Shah, Amrindra Pal
{"title":"基于碳化硅和氮化锆的表面等离子体共振传感器，用于检测大肠沙雷氏菌和溶血微球菌","authors":"Chou-Yi Hsu, Prakash Kanjariya, I. A. Ariffin, Asha Rajiv, Aditya Kashyap, G. D. Anbarasi Jebaselvi, Satish Choudhury, Yashpal Yadav, P. Sankara Rao, Sanjeev Kumar Shah, Amrindra Pal","doi":"10.1007/s00604-025-07161-6","DOIUrl":null,"url":null,"abstract":"<div><p>A novel surface plasmon resonance (SPR) biosensor design for point-of-care detection of different bacteria is presented. It consists of a SiO<sub>2</sub> prism, metal (Ag), silicon carbide (SiC), 2D materials of zirconium nitride (ZrN), and a sensing medium. The proposed structure’s angular reflectivity is investigated using the transfer matrix method (TMM) following optimization of the Ag and SiC layer thicknesses. For the various types of bacteria such as <i>Staphylococcus (S) aureus</i>, <i>faecalis 9790</i>, <i>aureus Duncan</i>, and <i>aureus 52A5</i>, the maximal sensitivity of 327, 362.45, 301.46, and 269.87°/RIU is achieved with remarkable minimum reflectance (<i>R</i><sub>min</sub>). According to simulation results, using a new class of 2D materials significantly improves the sensor performance over the conventional SPR configuration. Furthermore, the proposed SPR structure is presented with COMSOL Multiphysics to measure the electric field enhancement factor and intensity close to the ZrN material-sensing layer interface. Using the fabrication technologies to fabricate the proposed sensor as an SPR chip is worthwhile due to its real-time and label-free detection of malaria diseases. </p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 5","pages":""},"PeriodicalIF":5.3000,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Silicon carbide and zirconium nitride-based surface plasmon resonance sensors for detecting Serratia marcescens and Micrococcus lysodeikticus\",\"authors\":\"Chou-Yi Hsu, Prakash Kanjariya, I. A. Ariffin, Asha Rajiv, Aditya Kashyap, G. D. Anbarasi Jebaselvi, Satish Choudhury, Yashpal Yadav, P. Sankara Rao, Sanjeev Kumar Shah, Amrindra Pal\",\"doi\":\"10.1007/s00604-025-07161-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>A novel surface plasmon resonance (SPR) biosensor design for point-of-care detection of different bacteria is presented. It consists of a SiO<sub>2</sub> prism, metal (Ag), silicon carbide (SiC), 2D materials of zirconium nitride (ZrN), and a sensing medium. The proposed structure’s angular reflectivity is investigated using the transfer matrix method (TMM) following optimization of the Ag and SiC layer thicknesses. For the various types of bacteria such as <i>Staphylococcus (S) aureus</i>, <i>faecalis 9790</i>, <i>aureus Duncan</i>, and <i>aureus 52A5</i>, the maximal sensitivity of 327, 362.45, 301.46, and 269.87°/RIU is achieved with remarkable minimum reflectance (<i>R</i><sub>min</sub>). According to simulation results, using a new class of 2D materials significantly improves the sensor performance over the conventional SPR configuration. Furthermore, the proposed SPR structure is presented with COMSOL Multiphysics to measure the electric field enhancement factor and intensity close to the ZrN material-sensing layer interface. Using the fabrication technologies to fabricate the proposed sensor as an SPR chip is worthwhile due to its real-time and label-free detection of malaria diseases. </p><h3>Graphical Abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":705,\"journal\":{\"name\":\"Microchimica Acta\",\"volume\":\"192 5\",\"pages\":\"\"},\"PeriodicalIF\":5.3000,\"publicationDate\":\"2025-04-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microchimica Acta\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00604-025-07161-6\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchimica Acta","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s00604-025-07161-6","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Silicon carbide and zirconium nitride-based surface plasmon resonance sensors for detecting Serratia marcescens and Micrococcus lysodeikticus
A novel surface plasmon resonance (SPR) biosensor design for point-of-care detection of different bacteria is presented. It consists of a SiO2 prism, metal (Ag), silicon carbide (SiC), 2D materials of zirconium nitride (ZrN), and a sensing medium. The proposed structure’s angular reflectivity is investigated using the transfer matrix method (TMM) following optimization of the Ag and SiC layer thicknesses. For the various types of bacteria such as Staphylococcus (S) aureus, faecalis 9790, aureus Duncan, and aureus 52A5, the maximal sensitivity of 327, 362.45, 301.46, and 269.87°/RIU is achieved with remarkable minimum reflectance (Rmin). According to simulation results, using a new class of 2D materials significantly improves the sensor performance over the conventional SPR configuration. Furthermore, the proposed SPR structure is presented with COMSOL Multiphysics to measure the electric field enhancement factor and intensity close to the ZrN material-sensing layer interface. Using the fabrication technologies to fabricate the proposed sensor as an SPR chip is worthwhile due to its real-time and label-free detection of malaria diseases.
期刊介绍：
As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.
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