Acta cardiologicaPub Date : 2024-12-09DOI: 10.1080/00015385.2024.2432590
Eman Mahmoud, Ereny Refaat Boshra Tadress, Khaled Ahmed El-Khashab, Ahmed Fathy Elkhateeb, Mohammed Gamal Mossa
{"title":"Accuracy of 2-dimensional speckle tracking echocardiography in diagnosis of coronary artery stenosis in stable angina pectoris.","authors":"Eman Mahmoud, Ereny Refaat Boshra Tadress, Khaled Ahmed El-Khashab, Ahmed Fathy Elkhateeb, Mohammed Gamal Mossa","doi":"10.1080/00015385.2024.2432590","DOIUrl":"https://doi.org/10.1080/00015385.2024.2432590","url":null,"abstract":"<p><strong>Background: </strong>It's difficult to detect the severity of coronary artery disease in the patients who have stable angina pectoris. Echocardiography is a well-validated non-invasive diagnostic tool for detecting myocardial ischaemia, but judging wall motion abnormalities is subjective. Conventional echocardiography can assess radial mechanics only, so it cannot assess the sensitive longitudinal mechanics. 2-Dimensional strain echocardiography is a recent tool that has the ability to solve these drawbacks.</p><p><strong>Aim of study: </strong>To detect the accuracy of 2D-STE in prediction of significant coronary artery stenosis in the patients with stable angina pectoris.</p><p><strong>Methods: </strong>This study included 70 patients who have stable angina pectoris. Conventional and 2D speckle tracking echocardiography were done to all patients then compared with the coronary angiography results. Patients were classified into three groups according to their coronary arteries affection; patients with normal Coronaries, non-obstructed lesion and patients with significant lesion.</p><p><strong>Results: </strong>Our study results show that the mean GLS was (-18.67 ± 0.93) in normal cases, and it was (-15.82 ± 1.11) in non-obstructed lesions but GLS was (-13.19 ± 1.7) in patients with significant CAD. And the best cut-off point of GLS was reported as (-17.35%) with a sensitivity of 97.6% and specificity of 93.3%. Also we found that SLS results in significant lesions of LAD, LCX, RCA territory was (-16.3%, -15.95%, -17.45%) with sensitivity and specificity (87.8%, 93.3%), (70.7%, 93.3%), (82.9%, 93.3%) respectively.</p><p><strong>Conclusion: </strong>Global longitudinal strain has a good diagnostic significance over visual evaluation during conventional echocardiogram in predicting significant stenosis of the coronary arteries in patients with stable coronary artery disease. Segmental Longitudinal strain is also a sensitive tool to detect the affected Coronary Territory.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-8"},"PeriodicalIF":2.1,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-12-07DOI: 10.1080/00015385.2024.2436811
J Huart, P Vanderweckene, L Seidel, C Bovy, P Delanaye, B Dubois, S Grosch, P Xhignesse, A Saint-Remy, Krzesinski J-M, F Jouret
{"title":"Diagnostic and prognostic yields of ambulatory blood pressure measurements in haemodialysis patients: a 6-year longitudinal study.","authors":"J Huart, P Vanderweckene, L Seidel, C Bovy, P Delanaye, B Dubois, S Grosch, P Xhignesse, A Saint-Remy, Krzesinski J-M, F Jouret","doi":"10.1080/00015385.2024.2436811","DOIUrl":"https://doi.org/10.1080/00015385.2024.2436811","url":null,"abstract":"<p><strong>Background: </strong>Blood pressure (BP) control in haemodialysis (HD) patients is essential. Peri-dialytic BP levels do not accurately diagnose hypertension or predict the cardiovascular (CV) mortality.</p><p><strong>Methods: </strong>In this study, we recruited 43 adult patients who had been on chronic HD for ≥3 months. Seven-day home BP monitoring (HBPM) (values of Day1 discarded) and 44-h interdialytic ambulatory BP monitoring (iABPM) were performed. Pre- and post-dialysis BP levels were measured during the 6 dialysis sessions prior to iABPM. A 6-year follow-up was carried out to assess all-cause and CV mortality.</p><p><strong>Results: </strong>In patients considered as normotensive in pre-dialysis (<i>n</i> = 17), masked hypertension was found in 24% and 29% on the basis of iABPM and HBPM, respectively. Conversely, among hypertensive patients in pre-dialysis (<i>n</i> = 26), 'white-coat' hypertension was noted in 23% either by iABPM or HBPM. After a 6-year follow-up, 25 patients were deceased including 6 patients from CV causes. Day-time systolic BP measured by iABPM was associated with all-cause mortality in an adjusted model for age and gender (<i>p</i> = 0.045).</p><p><strong>Conclusion: </strong>In chronic HD patients, 44-h iABPM and 6-day HBPM show a reliable concordance and help to re-classify ∼25% of cases miscategorised based on pre-dialysis measurements. Day-time systolic BP levels using iABPM were significantly associated with 6-year all-cause mortality.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142790878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-12-03DOI: 10.1080/00015385.2024.2432693
Yuyuan Shu, Si-Qi Lyu, Jiangshan Tan, Han Zhang, Yimeng Wang, Lulu Wang, Yijing Xin, Yanmin Yang
{"title":"Sex differences in patients with atrial fibrillation and acute coronary syndrome or undergoing PCI: a real-world study.","authors":"Yuyuan Shu, Si-Qi Lyu, Jiangshan Tan, Han Zhang, Yimeng Wang, Lulu Wang, Yijing Xin, Yanmin Yang","doi":"10.1080/00015385.2024.2432693","DOIUrl":"https://doi.org/10.1080/00015385.2024.2432693","url":null,"abstract":"<p><strong>Background: </strong>In patients with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI), female patients have a worse short-term prognosis than male patients has been consistently concluded in many studies. However, the impact of sex differences on long-term prognosis remains uncertain. Additionally, women are underrepresented in clinical trials exploring optimal antithrombotic strategies in patients with atrial fibrillation (AF) and ACS or PCI. To bridge this gap, this study aimed to investigate sex differences in clinical characteristics, treatment, and long-term clinical outcomes in patients with AF and ACS or PCI.</p><p><strong>Patients and methods: </strong>This study included a total of 1237 patients with AF and ACS and 539 patients with AF and stable coronary artery disease (SCAD) who underwent PCI at the Fuwai Hospital of the Chinese Academy of Medical Sciences from January 2017 to December 2019. Patients were followed up until the end of 2021 to observe the occurrence of major adverse cardiovascular events (MACE). The relationship between sex and MACE was evaluated using Cox regression models and Kaplan-Meier's survival curves.</p><p><strong>Results: </strong>In patients with AF and ACS, multivariable COX regression analysis revealed that female patients were independently associated with a higher risk of MACE (HR = 1.45, 95% CI 1.11-1.89, <i>p</i> = .006). However, in AF patients with SCAD who underwent PCI, the analysis showed that female patients were not independently associated with MACE risk (HR = 1.12, 95% CI 0.62-2.03, <i>p</i> = .717).</p><p><strong>Conclusions: </strong>In patients with AF and ACS, females have a significantly higher risk of long-term MACE compared to males. However, among patients with AF and SCAD who underwent PCI, there was no significant difference in long-term MACE risk between males and females.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-14"},"PeriodicalIF":2.1,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-12-03DOI: 10.1080/00015385.2024.2436810
Nan Tang, Kangming Li, Qingdui Zhang, Huamei Sun, Cheng Peng, Ji Hao, Chunmei Qi
{"title":"Study of psychosocial factors and endothelial dysfunction in coronary heart disease patients.","authors":"Nan Tang, Kangming Li, Qingdui Zhang, Huamei Sun, Cheng Peng, Ji Hao, Chunmei Qi","doi":"10.1080/00015385.2024.2436810","DOIUrl":"https://doi.org/10.1080/00015385.2024.2436810","url":null,"abstract":"<p><strong>Objective: </strong>To provide valuable insight into the prevention and treatment of coronary heart disease, this study aimed to explore the association between psychosocial elements and endothelial dysfunction in diagnosed patients.</p><p><strong>Methods: </strong>Using a cross-sectional study design, we selected patients with coronary heart disease who visited the cardiology department of our hospital from January to December 2021. According to coronary angiography results, patients were divided into the coronary stenosis group (≥50%) and the normal coronary group (<50%), with 100 cases in each group. We assessed the levels of psychosocial factors using the Type A Behaviour Pattern Scale (TABP), Self-Rating Anxiety Scale (SAS), Social Support Rating Scale (SSRS), and Self-Rating Depression Scale (SDS). Endothelial synthesis of nitric oxide (NOx) and endothelium-dependent (EDF) and endothelium-independent (NEDF) vasodilation functions were measured and compared using enzyme-linked immunosorbent assay (ELISA) and colour Doppler ultrasonography, respectively.</p><p><strong>Results: </strong>Patients in the coronary stenosis group had significantly higher scores in Type A behaviour, anxiety, and depression and significantly lower scores in social support compared with the normal coronary group (<i>t</i> = 3.21, 4.15, 3.87; <i>p</i> < 0.05; <i>t</i> = -2.96; <i>p</i> < 0.05). EDF, NEDF, and NOx levels were significantly lower in the coronary stenosis group than in the normal coronary group (<i>t</i> = -4.32, -3.76, -4.67; <i>p</i> < 0.05). Psychosocial factors were negatively correlated with endothelial function indices (<i>r</i> = -0.31 to -0.48; <i>p</i> < 0.05). Multiple linear regression analysis revealed that Type A behavioural anxiety, depression, and social support were independent risk factors influencing endothelial dysfunction (<i>β</i> = -0.23, -0.26, -0.21, -0.19; <i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>A close relationship was observed between psychosocial factors and endothelial dysfunction in patients with coronary heart disease. Assessment and intervention of psychosocial factors in these patients should be strengthened to improve endothelial function and reduce the risk of cardiovascular events.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of reliability and radiation dose reduction in coronary artery calcium scoring by using a low tube current and low kilo-voltage peak with advanced modelled iterative reconstruction.","authors":"Debanjan Nandi, Niraj Nirmal Pandey, Sanjeev Kumar, Ambuj Roy, Priya Jagia","doi":"10.1080/00015385.2024.2436314","DOIUrl":"https://doi.org/10.1080/00015385.2024.2436314","url":null,"abstract":"<p><strong>Objective: </strong>The present study sought to compare the reliability and radiation dose of coronary artery calcium (CAC) scoring using low tube current (16 mAs), low kilo-voltage peak (100 kVp) and advanced modelled iterative reconstruction (ADMIRE 5) with the standard protocol (80 mAs, 120 kVp, ADMIRE 3).</p><p><strong>Material and methods: </strong>A prospective single centre study including 200 consecutive patients with suspected coronary artery disease referred for CT coronary angiography was conducted. All 200 patients underwent CAC scoring using the low current-low kVp protocol as well as standard protocol and were subdivided into a derivation and validation cohorts.</p><p><strong>Results: </strong>Correlation between CAC scores obtained using low current-low kVp protocol and standard protocol in derivation cohort was excellent (<i>r</i> = 0.99; <i>p</i> < 0.001). A linear regression model was used to derive a formula for predicting CAC that enabled conversion of CAC(low current-low kVp) to CAC(corrected) [CAC(corrected) = 1.067 × CAC(low current-low kVp)]. The formula was applied in validation cohort where CAC (corrected) showed excellent agreement with CAC(standard) (intraclass correlation coefficient, 0.9970; 95%CI, 0.9956-0.9980). Excellent agreement for risk classification (weighted kappa, 0.94379; 95%CI, 0.89629-0.99130) was observed between CAC(corrected) and CAC(standard) scores. The low current-low kVp protocol demonstrated an 88.87% reduction in radiation dose (0.0679 ± 0.01032 mSv vs. 0.610 ± 0.2403 mSv; <i>p</i> < 0.0001).</p><p><strong>Conclusion: </strong>The low current-low kVp protocol for CAC scoring has comparable reliability to the standard technique with significant radiation dose reduction. This extremely low-dose protocol may prove useful as an alternative to standard CAC scoring, particularly for screening in the low-to-intermediate risk population.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-8"},"PeriodicalIF":2.1,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-11-29DOI: 10.1080/00015385.2024.2432579
Ioannis Anagnostopoulos, Maria Kousta, Dimitrios Vrachatis, Sotiria Giotaki, Dimitra Katsoulotou, Christos Karavasilis, Nikolaos Schizas, Dimitrios Avramides, Georgios Giannopoulos, Spyridon Deftereos
{"title":"Peak left atrial longitudinal strain and incident atrial fibrillation in the general population: a systematic review and meta-analysis.","authors":"Ioannis Anagnostopoulos, Maria Kousta, Dimitrios Vrachatis, Sotiria Giotaki, Dimitra Katsoulotou, Christos Karavasilis, Nikolaos Schizas, Dimitrios Avramides, Georgios Giannopoulos, Spyridon Deftereos","doi":"10.1080/00015385.2024.2432579","DOIUrl":"https://doi.org/10.1080/00015385.2024.2432579","url":null,"abstract":"<p><strong>Background: </strong>Atrial fibrillation (AF) is the commonest supraventricular arrhythmia in adults. Timely AF diagnosis seems to ameliorate patients prognosis.</p><p><strong>Purpose: </strong>To investigate the association between peak left atrial longitudinal strain (PALS) and new onset AF in the general population.</p><p><strong>Objectives: </strong>We searched major electronic databases for articles assessing the relationship between PALS and incident AF.</p><p><strong>Results: </strong>Eight studies (11,145 patients) were analysed. Lower levels of PALS were significantly associated with higher risk of incident AF (HR: 0.95; 95%CI: 0.92-0.97, <i>I</i><sup>2</sup>: 83%). According to the diagnostic accuracy meta-analysis, PALS <33.4% presents 64% (95%CI: 46-79%) sensitivity and 69% (95%CI: 63-75%) specificity.</p><p><strong>Conclusions: </strong>In a relatively healthy population, lower levels of PALS were significantly associated with incident AF. The overall diagnostic accuracy was moderate. Lower levels of PALS seem to justify an opportunistic - rather than a systematic-screening approach. These findings could allow more efficient utilisation of healthcare resources.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-11-28DOI: 10.1080/00015385.2024.2434297
David Gómez Martín, Juan Sánchez-Rubio Lezcano, Georgina Fuertes Ferre, Laura Álvarez Roy, Marta López Ramón, José Antonio Diarte De Miguel
{"title":"Incomplete cor triatriatum dexter and percutaneous closure of atrial septal defects, a single-centre experience.","authors":"David Gómez Martín, Juan Sánchez-Rubio Lezcano, Georgina Fuertes Ferre, Laura Álvarez Roy, Marta López Ramón, José Antonio Diarte De Miguel","doi":"10.1080/00015385.2024.2434297","DOIUrl":"https://doi.org/10.1080/00015385.2024.2434297","url":null,"abstract":"<p><p>Cor Triatriatum Dexter (CTD) is a rare congenital heart malformation, with an estimated incidence of 0.025%, characterised by a membrane dividing the right atrium (RA) into two chambers. A variant, incomplete CTD (CTDi), occurs when the right membrane extends partially into the interatrial septum without fully dividing the RA. CTDi can be associated with interatrial septal defects, found in 5% of patients with atrial septal defects or a patent foramen ovale (PFO). The study reports three adult patients (46-53 years old) with CTDi and a PFO, all presenting cryptogenic stroke and referred for PFO closure. Two cases underwent percutaneous closure with guidance from fluoroscopy and 2D/3D transesophageal echocardiography (TEE), and the last one utilised intracardiac echocardiography (ICE) for device placement. In patients referred for PFO closure, CTDi is common and can complicate visualisation, prolong procedure times, and reduce success rates. Difficulties in device deployment and the risk of residual shunt or embolisation have been reported. The authors highlight that using oversizing techniques, traction manoeuvres during device deployment, and preoperative planning with advanced imaging (such as ICE or 3D TEE) are crucial for successful percutaneous closure in cases with CTDi and PFO.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-3"},"PeriodicalIF":2.1,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142737977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-11-26DOI: 10.1080/00015385.2024.2432588
Muhammad Osama, Safiyyah Ubaid, Raheel Ahmed, Maryam Ubaid
{"title":"'The role of the triglyceride-glucose index in assessing coronary artery disease risk in diabetes mellitus'.","authors":"Muhammad Osama, Safiyyah Ubaid, Raheel Ahmed, Maryam Ubaid","doi":"10.1080/00015385.2024.2432588","DOIUrl":"https://doi.org/10.1080/00015385.2024.2432588","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The association between peak tricuspid regurgitation velocity and 1-year heart failure readmission in hospitalised patients with heart failure with preserved ejection fraction.","authors":"Tianbo Wang, Xiaohan Liu, Yue Zhang, Chenli Fang, Junbo Xu","doi":"10.1080/00015385.2024.2421638","DOIUrl":"10.1080/00015385.2024.2421638","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to evaluate the association between peak tricuspid regurgitation velocity (TRV) and 1-year heart failure (HF) readmission in hospitalised patients with HF with preserved ejection fraction (HFpEF) because the impact of peak TRV on the short-term prognosis of these patients has been unclear.</p><p><strong>Methods: </strong>From January 2020 to December 2021, 513 hospitalised HFpEF patients age ≥ 60 years with 1-year follow-up were included in this study. Peak TRV was classified as normal (≤ 2.8 m/s) and high (> 2.8 m/s) value according to pulmonary hypertension probability.</p><p><strong>Results: </strong>Approximately 68.23% of HFpEF patients had a high peak TRV value. In the final adjusted Cox regression model, peak TRV was still independently associated with HF readmission (HR: 1.74, 95% CI: 1.19-2.55, <i>p</i> = 0.004). Furthermore, patients with high peak TRV were also associated with an increased risk of HF readmission (HR: 2.30, 95% CI: 1.31-4.04, <i>p</i> = 0.004), compared to those with normal peak TRV. After inverse probability of weighting, the risk of HF readmission in patients with high peak TRV was 2.53 (95% CI: 1.35-4.75, <i>p</i> = 0.004) compared to those with normal peak TRV. Additionally, Subgroup analysis revealed very elderly patients, male, and patients with hypertension had a significantly worse prognosis.</p><p><strong>Conclusion: </strong>Peak TRV is independently associated with HF readmission in hospitalised HFpEF patients. High peak TRV has a higher risk of HF readmission in patients age ≥ 80 years, male and patients with hypertension, indicating that special attention should be paid to these patients.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-8"},"PeriodicalIF":2.1,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}