Acta cardiologica最新文献_第3页

Clinical correlation of blood pressure recovery ratio following exercise testing and SYNTAX score in patients with stable coronary artery disease: its implications for CAD severity assessment. 稳定期冠心病患者运动试验后血压恢复率与SYNTAX评分的临床相关性：对冠心病严重程度评估的意义

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-06-30 DOI: 10.1080/00015385.2025.2524241

Özkan Bekler, Onur Kaypaklı, Asım Enhoş, Oğuz Akkuş, Alparslan Kurtul

{"title":"Clinical correlation of blood pressure recovery ratio following exercise testing and SYNTAX score in patients with stable coronary artery disease: its implications for CAD severity assessment.","authors":"Özkan Bekler, Onur Kaypaklı, Asım Enhoş, Oğuz Akkuş, Alparslan Kurtul","doi":"10.1080/00015385.2025.2524241","DOIUrl":"https://doi.org/10.1080/00015385.2025.2524241","url":null,"abstract":"Background: Blood pressure response during exercise testing provides valuable prognostic information. This study examined the association between blood pressure recovery ratio (BPRR) and SYNTAX score (SS) in patients with stable coronary artery disease (CAD). .Methods: A total of 98 patients (mean age 57.3 ± 7.3 years) with ≥50% lesion in ≥1 coronary artery who underwent coronary angiography after an exercise test were included. Patients were classified into low SS (≤22) and intermediate-high SS (>22) groups. BPRR was calculated as the ratio of third-minute to peak exercise systolic blood pressure (SBP).Results: BPRR was significantly higher in the intermediate-high SS group (0.96 ± 0.05) than in the low SS group (0.87 ± 0.06) (p < 0.001). It showed a positive correlation with SS, E/e' ratio, and left atrial volume, and a negative correlation with LVEF. In multivariate analysis, BPRR (OR: 1.446, p < 0.001) and LVEF (OR: 0.802, p = 0.005) were independent predictors of intermediate-high SS. Each 0.01 unit increase in BPRR increased risk by 44.6%. ROC analysis identified a BPRR cut-off of 0.928 (AUC = 0.892).Conclusions: BPRR, a simple and accessible parameter from exercise testing, is independently associated with CAD severity. It may enhance the non-invasive prediction of intermediate to high SS.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cross-prevalence of large and small vessels disease in T2DM: overview from a Belgian academic centre. T2DM中大、小血管疾病的交叉流行：来自比利时学术中心的综述

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-06-27 DOI: 10.1080/00015385.2025.2524239

Fabian O Lurquin, Elise L Petit, Sylvie A Ahn, Michel F Rousseau, Michel P Hermans

{"title":"Cross-prevalence of large and small vessels disease in T2DM: overview from a Belgian academic centre.","authors":"Fabian O Lurquin, Elise L Petit, Sylvie A Ahn, Michel F Rousseau, Michel P Hermans","doi":"10.1080/00015385.2025.2524239","DOIUrl":"https://doi.org/10.1080/00015385.2025.2524239","url":null,"abstract":"Aims: To document the cross-prevalence of overall macro- and microangiopathy in T2DM and identify common and vessel-size-specific variables associated with comorbidities.Methods: Cross-sectional study of 876 T2DM patients to assess frequency of macrovascular and microvascular target organ damage (TOD). Logistic regressions were performed to identify common and specific variables linked to TODs.Results: Overall prevalence of Mic and Mac were 41% and 33%, respectively; 45.5% had no comorbidities (Mic[-]Mac[-]); 21% had microangiopathy only (Mic[+]Mac[-]), 13.5% had macroangiopathy only (Mic[-]Mac[+]); 20% both (Mic[+]Mac[+]). Compared to Mic[-]Mac[-], the 3 TOD groups had more (micro)albuminuria. Mic[-]Mac[+] and Mic[+]Mac[+] had more diabetic foot (DF) and heart failure (HF) than Mic[-]Mac[-]. Mic[+]Mac[+] suffered more often from atrial fibrillation than Mic[-]Mac[-]. Mic[+]Mac[+] suffered twice more from peripheral artery disease and thrice higher DF, and 1.5 times more HF vs. Mic[-]Mac[+]. Non-HDL-C, remnant cholesterol, sleep apnoea and non-O blood group were associated with Mic/Mac.Conclusions: This transversal analysis provides quantitative data on cross-prevalence of micro- and macroangiopathies in a 3rd line hospital. Small and large-vessel diseases are highly intertwined with atherosclerotic, cardiometabolic and cardiorenal co-morbidities.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The predictive value of the aggregate index of systemic inflammation for contrast-induced acute kidney injury in patients undergoing coranary angiography. 全身性炎症综合指数对冠状动脉造影患者造影剂急性肾损伤的预测价值。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-06-26 DOI: 10.1080/00015385.2025.2524237

Tuba Unkun, Serdar Fidan, Sevim Türkday Derebey, Büsra Güvendi Sengör, Ahmet Karaduman, Gülümser Sevgin Halil, Gokhan Alıcı, Birol Özkan, Ali Karagöz, Süleyman Cagan Efe

{"title":"The predictive value of the aggregate index of systemic inflammation for contrast-induced acute kidney injury in patients undergoing coranary angiography.","authors":"Tuba Unkun, Serdar Fidan, Sevim Türkday Derebey, Büsra Güvendi Sengör, Ahmet Karaduman, Gülümser Sevgin Halil, Gokhan Alıcı, Birol Özkan, Ali Karagöz, Süleyman Cagan Efe","doi":"10.1080/00015385.2025.2524237","DOIUrl":"https://doi.org/10.1080/00015385.2025.2524237","url":null,"abstract":"Background: Contrast-induced acute kidney injury (CI-AKI) occurs as a result of the use of contrast media during coronary interventions and can lead to serious complications.Aim: To investigate the predictive value of the pre-procedural aggregate index of systemic inflamation (AISI) for the development of CI-AKI in patients with chronic coronary artery disease suspicion who underwent coronary angiography (CAG) or percutaneous coronary intervention (PCI).Methods: This retrospective cohort study conducted on 166 patients with chronic coronary artery disease suspicion who underwent CAG or PCI. The neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII) and AISI levels were calculated. The relationship between these parameters and the development of CI-AKI within 72 h after intervention was analysed.Results: CI-AKI occurred in 25 patients (15.1%). Upon conducting a likelihood ratio test to compare full and reduced models, it was found that in the reduced model, variables such as NLR, SII and AISI were independently predictors of CI-AKI, The NLR model (Odds ratio (OR) =1.32, 95% CI [1.16-1.52]), SII model (OR =3.41, 95% CI [1.92-6.08]), and AISI model (OR =4.81, 95% CI [2.42-9.60]). An increase in AISI was linearly associated with CI-AKI and showed the highest prediction for CI-AKI.Conclusion: These findings demonstrate that AISI is a significant independent predictor for CI-AKI in patients undergoing CAG or PCI.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Commentary on 'Effect of dapagliflozin on the no-reflow phenomenon in patients with acute myocardial infarction and type iI diabetes mellitus'. 《达格列净对急性心肌梗死合并2型糖尿病患者无血流现象的影响》综述。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-06-24 DOI: 10.1080/00015385.2025.2524238

Cedric Davidsen

引用次数: 0

Coronary computed tomography angiography enables detection of coronary-right ventricular fistula missed by selective coronary angiography: a case report. 冠状动脉计算机断层血管造影能够发现选择性冠状动脉造影遗漏的冠状-右心室瘘：一个病例报告。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-06-18 DOI: 10.1080/00015385.2025.2520030

Shuyi Hu, Jiatian Yi, Hua Yan, Dan Song, Handong Zhu

引用次数: 0

Echocardiographic practices in pulmonary hypertension: survey results and literature review. 超声心动图在肺动脉高压中的应用：调查结果和文献综述。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-06-17 DOI: 10.1080/00015385.2025.2518645

Patrizio Lancellotti, Werner Budts, Jean-Luc Vachiery

引用次数: 0

Conventional versus modified superior vena cava ablation for atrial fibrillation: efficiency and recurrent burden. 传统与改良上腔静脉消融治疗心房颤动：效率和复发负担。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-06-17 DOI: 10.1080/00015385.2025.2516945

Yanjia Chen, Haobin Zhou, Lanlan Wu, Yao Lu, Liwei He, Mingwei Bu, Dingli Xu, Xingfu Huang

{"title":"Conventional versus modified superior vena cava ablation for atrial fibrillation: efficiency and recurrent burden.","authors":"Yanjia Chen, Haobin Zhou, Lanlan Wu, Yao Lu, Liwei He, Mingwei Bu, Dingli Xu, Xingfu Huang","doi":"10.1080/00015385.2025.2516945","DOIUrl":"https://doi.org/10.1080/00015385.2025.2516945","url":null,"abstract":"Introduction: The superior vena cava (SVC) is one of the most important non-pulmonary vein origins of atrial fibrillation (AF). Careful treatment is required to reduce AF recurrence following ablation. Previous SVC ablation strategies have had relatively low success rates, longer procedure times, and an increased risk of serious complications. Therefore, we propose a modified approach to improve the feasibility of SVC isolation (SVCI).Methods: A total of 234 patients with AF were divided into two groups. Group A (108 patients) underwent SVCI using a conventional approach, while group B (126 patients) underwent a modified three-step ablation approach. The modified SVC ablation plane was located 0.5-1 cm above the intersection of the right superior pulmonary vein (RSPV) and the left atrium (LA) roof in the posterior-anterior (PA) view. SVCI was avoided at sites with phrenic nerve (PN) capture.Results: There were fewer sites of ablation in group B than in group A (11.8 ± 4.7 versus 18.0 ± 7.1). Group B had significantly shorter radiofrequency time and total time of SVCI. Additionally, group B had a much lower incidence of PN injury. During a mean follow-up period of 35.0 ± 0.7 months, patients in group A had a lower AF recurrence-free rate compared to those in group B (75.0% and 86.2%, respectively; log-rank p < .005) after initial ablation.Conclusions: The modified SVCI approach demonstrates greater efficiency and a lower recurrence rate than the conventional approach, making it a potentially superior ablation strategy.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144315747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NLR/inflammasome pathway in cardiovascular disorders: from pathogenesis to potential therapies. 心血管疾病的NLR/炎性体通路：从发病机制到潜在治疗方法。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-06-16 DOI: 10.1080/00015385.2025.2515322

Behnaz Hammami, Nasrin Zare, Ali Sohrabi, Maryam Alimohammady, Mohammad Sabet Eghlidi, Nastaran Naderi

{"title":"NLR/inflammasome pathway in cardiovascular disorders: from pathogenesis to potential therapies.","authors":"Behnaz Hammami, Nasrin Zare, Ali Sohrabi, Maryam Alimohammady, Mohammad Sabet Eghlidi, Nastaran Naderi","doi":"10.1080/00015385.2025.2515322","DOIUrl":"https://doi.org/10.1080/00015385.2025.2515322","url":null,"abstract":"The inflammasome is a multimeric protein complex that plays an essential role in the innate immune response by triggering the cleavage and activation of the proinflammatory cytokines interleukins (IL)-1β and IL-18. The dysregulation of NLRs and subsequent inflammasome activation has emerged under various pathologic conditions that contribute to the progression of heart failure, including pressure overload, acute or chronic overactivation of the sympathetic system, myocardial infarction, and diabetic cardiomyopathy. Our study unfolds by examining the pivotal role of the NLRP3 inflammasome in cardiac inflammation and fibrosis, exploring the intricate signalling pathways, including NLRs, involved in the initiation and progression of heart failure. Insights from preclinical and clinical studies indicate the use of potential therapeutic strategies targeting NLRs and the inflammasome to mitigate adverse cardiac outcomes. This review aims to consolidate existing knowledge, pinpoint gaps in our understanding, and propose directions for future research. This study may elucidate the function of NLRs/inflammasomes in heart failure and establishes a foundation for subsequent research focused on developing targeted therapeutics to alleviate inflammatory pathways associated with heart failure.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-25"},"PeriodicalIF":2.1,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiomics and machine learning for predicting valve vegetation in infective endocarditis: a comparative analysis of mitral and aortic valves using TEE imaging. 放射组学和机器学习用于预测感染性心内膜炎的瓣膜植被：使用TEE成像的二尖瓣和主动脉瓣的比较分析。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-06-12 DOI: 10.1080/00015385.2025.2500887

Farid Esmaely, Pardis Moradnejad, Shabnam Boudagh, Ahmad Bitarafan-Rajabi

{"title":"Radiomics and machine learning for predicting valve vegetation in infective endocarditis: a comparative analysis of mitral and aortic valves using TEE imaging.","authors":"Farid Esmaely, Pardis Moradnejad, Shabnam Boudagh, Ahmad Bitarafan-Rajabi","doi":"10.1080/00015385.2025.2500887","DOIUrl":"https://doi.org/10.1080/00015385.2025.2500887","url":null,"abstract":"Background: Detecting valve vegetation in infective endocarditis (IE) poses challenges, particularly with mechanical valves, because acoustic shadowing artefacts often obscure critical diagnostic details. This study aimed to classify native and prosthetic mitral and aortic valves with and without vegetation using radiomics and machine learning.Methods: 286 TEE scans from suspected IE cases (August 2023-November 2024) were analysed alongside 113 rejected IE as control cases. Frames were preprocessed using the Extreme Total Variation Bilateral (ETVB) filter, and radiomics features were extracted for classification using machine learning models, including Random Forest, Decision Tree, SVM, k-NN, and XGBoost. in order to evaluate the models, AUC, ROC curves, and Decision Curve Analysis (DCA) were used.Results: For native mitral valves, SVM achieved the highest performance with an AUC of 0.88, a sensitivity of 0.91, and a specificity of 0.87. Mechanical mitral valves also showed optimal results with SVM (AUC: 0.85, sensitivity: 0.73, specificity: 0.92). Native aortic valves were best classified using SVM (AUC: 0.86, sensitivity: 0.87, specificity: 0.86), while Random Forest excelled for mechanical aortic valves (AUC: 0.81, sensitivity: 0.89, specificity: 0.78).Conclusion: These findings suggest that combining the models with the clinician's report may enhance the diagnostic accuracy of TEE, particularly in the absence of advanced imaging methods like PET/CT.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-18"},"PeriodicalIF":2.1,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of left atrial mechanical dispersion by real-time 3D echocardiography combined with DR-FLASH score for predicting late recurrence after ablation in paroxysmal atrial fibrillation. 实时三维超声心动图评价左房机械离散度结合DR-FLASH评分预测阵发性心房颤动消融后晚期复发

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-06-11 DOI: 10.1080/00015385.2025.2516944

Heng Sun, Run-Yu Zhu, Hao-Tian Hu, Chang Zhou, Wen-Shu Hu, Xin-Yi Li, Ao-Yi Zhang, Dian Shen

{"title":"Assessment of left atrial mechanical dispersion by real-time 3D echocardiography combined with DR-FLASH score for predicting late recurrence after ablation in paroxysmal atrial fibrillation.","authors":"Heng Sun, Run-Yu Zhu, Hao-Tian Hu, Chang Zhou, Wen-Shu Hu, Xin-Yi Li, Ao-Yi Zhang, Dian Shen","doi":"10.1080/00015385.2025.2516944","DOIUrl":"https://doi.org/10.1080/00015385.2025.2516944","url":null,"abstract":"Background: Atrial fibrillation (AF) is a common arrhythmia causing serious health complications. Catheter ablation is used to treat AF, but the risk of recurrence is high. The DR-FLASH score, which predicts recurrence, has limited sensitivity and specificity. Left atrial mechanical dispersion (LAMD) is an effective index that reflects the synchronisation of left atrial mechanical movement and the degree of early remodelling.Objective: This study aimed to assess the predictive value of LAMD and the DR-FLASH score for late recurrence after ablation.Methods: The general clinical data, structural, and functional parameters of both the recurrence group and the non-recurrence group were collected. Univariate and multivariate logistic regression analysis explored the independent predictors of late recurrence after AF ablation. The ROC curve was used to evaluate the effectiveness of LAMD and DR-FLASH score on recurrence after AF ablation.Results: The study included 102 AF patients and 31 healthy controls. LAMD was found to be an independent predictor of recurrence, and combining it with the DR-FLASH score improved predictive efficiency, with an area under the curve (AUC) of 0.875, sensitivity of 77.8%, and specificity of 88.0%.Conclusion: LAMD combined with the DR-FLASH score can help identify high-risk patients and potentially reduce recurrence rates.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0