Clinical correlation of blood pressure recovery ratio following exercise testing and SYNTAX score in patients with stable coronary artery disease: its implications for CAD severity assessment.

IF 2.5 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Acta cardiologica Pub Date : 2025-06-30 DOI:10.1080/00015385.2025.2524241

Özkan Bekler, Onur Kaypaklı, Asım Enhoş, Oğuz Akkuş, Alparslan Kurtul

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引用次数: 0

Abstract

Background: Blood pressure response during exercise testing provides valuable prognostic information. This study examined the association between blood pressure recovery ratio (BPRR) and SYNTAX score (SS) in patients with stable coronary artery disease (CAD). .

Methods: A total of 98 patients (mean age 57.3 ± 7.3 years) with ≥50% lesion in ≥1 coronary artery who underwent coronary angiography after an exercise test were included. Patients were classified into low SS (≤22) and intermediate-high SS (>22) groups. BPRR was calculated as the ratio of third-minute to peak exercise systolic blood pressure (SBP).

Results: BPRR was significantly higher in the intermediate-high SS group (0.96 ± 0.05) than in the low SS group (0.87 ± 0.06) (p < 0.001). It showed a positive correlation with SS, E/e' ratio, and left atrial volume, and a negative correlation with LVEF. In multivariate analysis, BPRR (OR: 1.446, p < 0.001) and LVEF (OR: 0.802, p = 0.005) were independent predictors of intermediate-high SS. Each 0.01 unit increase in BPRR increased risk by 44.6%. ROC analysis identified a BPRR cut-off of 0.928 (AUC = 0.892).

Conclusions: BPRR, a simple and accessible parameter from exercise testing, is independently associated with CAD severity. It may enhance the non-invasive prediction of intermediate to high SS.

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稳定期冠心病患者运动试验后血压恢复率与SYNTAX评分的临床相关性：对冠心病严重程度评估的意义

背景：运动试验期间的血压反应提供了有价值的预后信息。本研究探讨稳定型冠心病（CAD）患者血压恢复率（BPRR）与SYNTAX评分（SS）的关系。方法：纳入98例（平均年龄57.3±7.3岁）≥1条冠状动脉病变≥50%且在运动试验后行冠状动脉造影的患者，平均年龄57.3±7.3岁。将患者分为低SS（≤22）组和中高SS（>22）组。BPRR计算为第三分钟与运动峰值收缩压（SBP）之比。结果：中高SS组BPRR（0.96±0.05）显著高于低SS组（0.87±0.06）（p < 0.001）。与SS、E/ E′比、左房容积呈正相关，与LVEF负相关。在多因素分析中，BPRR （OR: 1.446, p < 0.001）和LVEF （OR: 0.802, p = 0.005）是中高SS的独立预测因子，BPRR每增加0.01个单位，风险增加44.6%。ROC分析发现BPRR截止值为0.928 （AUC = 0.892）。结论：BPRR是运动试验中一个简单易行的参数，与CAD严重程度独立相关。它可以增强中高SS的无创预测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta cardiologica 医学-心血管系统

CiteScore

2.50

自引率

12.50%

发文量

115

审稿时长

2 months

期刊介绍： Acta Cardiologica is an international journal. It publishes bi-monthly original, peer-reviewed articles on all aspects of cardiovascular disease including observational studies, clinical trials, experimental investigations with clear clinical relevance and tutorials.