Acta cardiologicaPub Date : 2025-03-19DOI: 10.1080/00015385.2025.2480939
Kaat Verhenne, Pieter De Meester, Geert Schuurmans, Philip Moons, Els Troost, Alexander Van De Bruaene, Werner Budts
{"title":"Volume challenge in women with congenital heart disease during reproductive age and pregnancy outcomes.","authors":"Kaat Verhenne, Pieter De Meester, Geert Schuurmans, Philip Moons, Els Troost, Alexander Van De Bruaene, Werner Budts","doi":"10.1080/00015385.2025.2480939","DOIUrl":"https://doi.org/10.1080/00015385.2025.2480939","url":null,"abstract":"<p><strong>Background: </strong>Thanks to medical improvements in the care for patients with congenital heart disease (CHD), women with CHD reach reproductive age. Pregnancy is not without risk due to the cardiovascular changes that occur. University Hospitals Leuven use a standardised protocol, including a catheterisation and volume challenge, to assess these women before pregnancy. This protocol has never been evaluated.</p><p><strong>Objective: </strong>The primary aim was to evaluate this volume challenge protocol. The second objective was to investigate whether hemodynamic data obtained during cardiac catheterisation were associated with maternal and/or neonatal outcome.</p><p><strong>Methods: </strong>A single-centre, retrospective study was conducted. Primarily, changes in catheterisation measurements were evaluated. Second, correlation statistics investigated associations between catheterisation data and outcome.</p><p><strong>Results: </strong>Twenty-five women, with nine different CHDs were eligible for inclusion and underwent a catheterisation with volume challenge. Significant changes in pre- and post-volume challenge measurements were observed in the mean averaged systemic venous pressure (ASVP) (<i>p</i> < 0.001), diastolic and mean pulmonary artery pressures (<i>p</i> < 0.001), and the pulmonary capillary wedge pressure (<i>p</i> < 0.001). A negative correlation was observed between the pre-test ASVP and the neonatal gestational age at delivery (<i>p</i> = 0.002). Another negative correlation was found between the post-test cardiac index (CI) and gestational age at delivery (<i>p</i> = 0.049) and birthweight (<i>p</i> = 0.018).</p><p><strong>Conclusion: </strong>The results suggest that higher ASVP is associated with lower gestational age at delivery. Remarkably, higher CI was related with lower gestational age and birthweight. However, our data do not support that a systematic volume challenge in women with CHD can be considered as a reliable prediction test.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-8"},"PeriodicalIF":2.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2025-03-18DOI: 10.1080/00015385.2025.2480958
Mohammad Sahebkar, Najme Lagzian, Mohammad Reza Armat, Sarina Ramtin, Seyyedeh Samaneh Tabaee, Abdolghader Assarroudi
{"title":"Enhancing predictive accuracy of the 13-item Acute Coronary Syndrome checklist: a novel approach to improving risk assessment and diagnosis.","authors":"Mohammad Sahebkar, Najme Lagzian, Mohammad Reza Armat, Sarina Ramtin, Seyyedeh Samaneh Tabaee, Abdolghader Assarroudi","doi":"10.1080/00015385.2025.2480958","DOIUrl":"https://doi.org/10.1080/00015385.2025.2480958","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the discriminatory capacity of the 13-Item ACS checklist and improve the accuracy of ACS diagnosis through the application of weighted regression analysis.</p><p><strong>Materials and methods: </strong>This predictive correlation study enrolled 300 patients admitted to Emergency Department between February 2021 and January 2022. The ACS checklist was administered upon initial triage, followed by patient tracking over a one-month hospitalisation period, capturing ACS diagnoses. Data analysis employed STATA 17 and MEDCALC 20.0.13 software.</p><p><strong>Results: </strong>Findings indicated that patients with sweating and shortness of breath symptoms had a heightened likelihood of true ACS diagnosis by 14% and 11%, respectively, compared to those without ACS (<i>p</i> = 0.005 and 0.019). Conversely, palpitations were associated with a 20% decreased likelihood of authentic ACS diagnosis (<i>p</i> < 0.001). Integration of significant regression coefficients - palpitation severity (-21), sweating severity (13.7), and shortness of breath severity (11) demonstrated significant discriminatory enhancements in the checklists. The weighted 13-item ACS checklist surpassed the unweighted version's performance, yielding superior discriminatory power for ACS diagnosis (<i>p</i> < 0.001 and <i>p</i> = 0.089). The weighted checklist elevated the AUC score from 55% to 70%.</p><p><strong>Conclusions: </strong>Incorporating weighted factors - shortness of breath severity, sweating severity, and palpitations severity - into the checklist notably enhanced ACS identification. However, it's important to note that this tool, while showing promise, is not intended to serve as a standalone diagnostic tool for ACS. Instead, this tool has the potential to enhance risk assessment and aid in clinical decision-making.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-7"},"PeriodicalIF":2.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2025-03-11DOI: 10.1080/00015385.2025.2476887
Astrid Declercq, Vincent Floré, Nico Van de Veire
{"title":"The scalpel's dilemma: weighing the mortality risk of combined surgical aortic valve replacement and coronary artery bypass grafting.","authors":"Astrid Declercq, Vincent Floré, Nico Van de Veire","doi":"10.1080/00015385.2025.2476887","DOIUrl":"https://doi.org/10.1080/00015385.2025.2476887","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2025-03-11DOI: 10.1080/00015385.2025.2476890
Ramazan Aslan, Murat Özmen, Faik Özel, Erhan Arıkan, İsa Ardahanlı
{"title":"Enhancing the evidence base: constructive feedback on the comparative effectiveness of torsemide and furosemide in heart failure.","authors":"Ramazan Aslan, Murat Özmen, Faik Özel, Erhan Arıkan, İsa Ardahanlı","doi":"10.1080/00015385.2025.2476890","DOIUrl":"https://doi.org/10.1080/00015385.2025.2476890","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2025-03-10DOI: 10.1080/00015385.2025.2471654
Alina Ghazou, Mayar El-Haddad, Amany Abdelaziz Hasan, Muhammad Ashraf Saleh, Tamer Ahmed Mahmoud, Abderrazzak Elomari, Manar Alaa Mabrouk, Mostafa AbdulSattar, Aya Abdul Fattah Taha
{"title":"Bedtime vs. morning aspirin intake on the diurnal variability of blood pressure and platelet aggregation for the prevention of coronary artery diseases: a systematic review and meta-analysis.","authors":"Alina Ghazou, Mayar El-Haddad, Amany Abdelaziz Hasan, Muhammad Ashraf Saleh, Tamer Ahmed Mahmoud, Abderrazzak Elomari, Manar Alaa Mabrouk, Mostafa AbdulSattar, Aya Abdul Fattah Taha","doi":"10.1080/00015385.2025.2471654","DOIUrl":"https://doi.org/10.1080/00015385.2025.2471654","url":null,"abstract":"<p><strong>Purpose: </strong>Low-dose aspirin had been widely used for secondary prevention of cardiovascular disease. Chronopharmacology of arterial hypertension and platelet aggregation impacts the long-term thromboembolic risk in patients with cardiovascular disease. Therefore, clinical studies have proposed optimising aspirin dosing time. Therefore, the aim of this study is to investigate the effect of timing of administration of low dose aspirin on the mean blood pressure profile and platelet aggregation for primary and secondary prevention of cardiovascular disease.</p><p><strong>Methods: </strong>The literature search included PubMed, Scopus, Web of Science, and Cochrane CENTRAL. The identification of included randomised controlled trials (RCTs) followed a systematic literature review (SLR) in accordance with the guidelines and recommendations of The Cochrane Collaboration. RCTs on the effect of aspirin intake at different times of the day on blood pressure and platelet aggregation in adults with coronary arterial disease or arterial hypertension for primary or secondary prevention were included.</p><p><strong>Results: </strong>Meta-analysis included 11 RCTs out of 6495 studies. In terms of patients' characteristics, the overall mean age was 52.7, and 65% of the patients were men. The pooled mean differences of systolic and diastolic blood pressure were significant in the bedtime group in 'prehypertension and untreated hypertension' subgroup (MD = -8.20, 95% CI [-9.80, -6.61], MD = -4.02, 95% CI [-5.94, -2.11]; respectively) while no significant difference was seen in the 'treated hypertension and CVD' subgroup in both SBP and DBP (MD = -0.08, 95% CI [-2.65, 2.5], MD = -0.46, 95% CI [-2.20, 1.28]; respectively). The included studies demonstrating the effect of bedtime aspirin on platelet aggregation showed a significant reduction in platelet aggregation favouring the bedtime group with a mean difference of -21.15, 95% Cl [-32.78, -9.53].</p><p><strong>Conclusion: </strong>The study shows an additional antihypertensive benefit of bedtime aspirin intake in the prehypertension and untreated hypertension groups, which may provide a positive long-term impact on cardiovascular risk in hypertensive patients. Moreover, the study revealed an additional benefit of bedtime aspirin intake on platelet aggregation, particularly in the morning hours when most thromboembolic events were found to occur.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2025-03-03DOI: 10.1080/00015385.2025.2469000
Jacopo Francesco Imberti, Alberto Fisce, Giuseppe Boriani
{"title":"Access to implantable cardioverter defibrillator therapy within and across countries: the barriers still persist.","authors":"Jacopo Francesco Imberti, Alberto Fisce, Giuseppe Boriani","doi":"10.1080/00015385.2025.2469000","DOIUrl":"https://doi.org/10.1080/00015385.2025.2469000","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-3"},"PeriodicalIF":2.1,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143539962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}