Acta cardiologica最新文献

{"title":"Predicting heart failure mortality using the Danish Comorbidity Index for Acute Myocardial Infarction (DANCAMI).","authors":"Usama Sikandar, Kasper Bonnesen, Uffe Heide-Jørgensen, Morten Schmidt","doi":"10.1080/00015385.2025.2452131","DOIUrl":"https://doi.org/10.1080/00015385.2025.2452131","url":null,"abstract":"<p><strong>Background: </strong>Patients with congestive heart failure (HF) are often burdened with comorbidities that increase mortality. Comorbidity indices provide a standardised method to measure comorbidity burden and predict prognosis. We aimed to investigate whether the Danish Comorbidity Index for Acute Myocardial Infarction (DANCAMI) can discriminate mortality in patients with HF.</p><p><strong>Methods: </strong>We conducted a population-based cohort study of all adult Danish patients with first-time HF during 1995-2020 (<i>N</i> = 311,628). We used logistic regression to calculate the area under the receiver operating characteristic curve (AUC) for cardiovascular and all-cause mortality within 30 days, 1 year, and 10 years of diagnosis. The AUCs were computed for a model including age and sex (baseline) and models also including the DANCAMI, the Charlson Comorbidity Index (CCI), or the Elixhauser Comorbidity Index (ECI).</p><p><strong>Results: </strong>For all-cause mortality, the AUCs were higher for the DANCAMI than for the baseline model (30-day: 0.688 vs. 0.662; 1-year: 0.715 vs. 0.680; 10-year: 0.840 vs. 0.810). For cardiovascular mortality, the AUCs were comparable between the DANCAMI and the baseline model (30-day: 0.683 vs. 0.676; 1-year: 0.690 vs. 0.684; 10-year: 0.659 vs. 0.658). For both 30-day, 1-year, and 10-year all-cause and cardiovascular mortality, the AUCs for the CCI and the ECI were comparable to those for the DANCAMI.</p><p><strong>Conclusions: </strong>Adding the DANCAMI to a model including patient age and sex improved discrimination of short and long-term all-cause mortality but not of cardiovascular mortality.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infectious pseudoaneurysm of the apex of the left cardiac ventricle in a drug addict patient: report of a case.","authors":"Vincent Demesmaker, Kristof De Brabandere, Benjamin Born, Parla Astarci","doi":"10.1080/00015385.2025.2496565","DOIUrl":"https://doi.org/10.1080/00015385.2025.2496565","url":null,"abstract":"<p><p>A 43-year-old patient presented to the emergency room due to chest pain, loss of consciousness and an episode of pyrexia. The assessment quickly revealed an infectious pseudoaneurysm of 4.5 cm of the left ventricle apex. The patient underwent emergency cardiac surgery with a large resection of the apical left ventricular cardiac tissues. The surgical reconstruction was performed using a bovine pericardial patch. Associate treatment was targeted intra-veinous (IV) antibiotics, post-operative exercises to recover the ejection fraction.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-3"},"PeriodicalIF":2.1,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of dapagliflozin on the no-reflow phenomenon in patients with acute myocardial infarction and type II diabetes mellitus.","authors":"Alaa Quisi, Nur Selin Nacar Quisi, Gökhan Alıcı, İdil Donma, Abdullah Yıldırım, Ömer Genç","doi":"10.1080/00015385.2025.2500892","DOIUrl":"https://doi.org/10.1080/00015385.2025.2500892","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the effect of dapagliflozin on the no-reflow phenomenon in patients with type II diabetes mellitus (T2DM) and acute myocardial infarction (AMI) who underwent percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>This single-center, observational cohort study included a total of 829 consecutive T2DM patients who were diagnosed with AMI and underwent PCI within 24 h of the onset of symptoms. Only patients using dapagliflozin (10 mg per day) for more than one year were considered as patients using dapagliflozin. The no-reflow phenomenon was defined as inadequate myocardial perfusion within a segment of the coronary circulation without angiographic evidence of mechanical vessel obstruction, dissection, or residual stenosis after PCI.</p><p><strong>Results: </strong>Four hundred and thirty-four patients were diagnosed with ST-segment elevation myocardial infarction (STEMI), and 395 patients were diagnosed with non-ST-segment elevation myocardial infarction (NSTEMI). Forward conditional logistic regression analysis demonstrated that the estimated glomerular filtration rate (OR = 0.940, 95% CI: 0.900 to 0.982, <i>p</i> = 0.006), SYNTAX score I (OR = 1.338, 95% CI: 1.179 to 1.520, <i>p</i> < 0.001), and dapagliflozin use (OR = 0.030, 95% CI: 0.004 to 0.228, <i>p</i> = 0.001) were independent predictors of the no-reflow phenomenon in STEMI. However, dapagliflozin use (OR = 0.112, 95% CI: 0.013 to 0.933, <i>p</i> = 0.043) was the only independent predictor of the no-reflow phenomenon in NSTEMI.</p><p><strong>Conclusion: </strong>Lower rates of the no-reflow phenomenon were observed in T2DM patients taking dapagliflozin, diagnosed with AMI, and underwent PCI. However, this finding requires further investigation.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beneficial effects of doxycycline on atrial electrical remodelling in a rat model of atrial fibrillation.","authors":"Kai Zhang, Zuowang Ma, Yu Yang, Guangping Li","doi":"10.1080/00015385.2025.2500888","DOIUrl":"https://doi.org/10.1080/00015385.2025.2500888","url":null,"abstract":"<p><strong>Background: </strong>Previous studies showed that doxycycline (Dox) can attenuate chronic intermittent hypoxia (CIH)-induced atrial fibrosis in rats. On this basis, we further investigated the effects of Dox on CIH-induced atrial electrical remodelling.</p><p><strong>Methods: </strong>Rats were randomised into 3 groups: Control group, CIH group, and CIH with Dox treatment (CIH-D) group (<i>n</i> = 30). CIH and CIH-D rats were subjected to CIH 8 h/d for 6 weeks. After collecting the basic parameters of the rats, atrial fibrillation (AF) inducibility, conduction inhomogeneity, and epicardial conduction velocity were examined by <i>in vitro</i> cardiac electrophysiology experiments. The expression levels of ion channel subunits in the atrium were detected by Western blotting. Whole-cell patch clamp experiments were used to recorded action potential (AP), I_Ca-L, I_to, and the kinetic parameters.</p><p><strong>Results: </strong>Compared to the Control rats, CIH rats showed increased AF inducibility, conduction inhomogeneity, and expression levels of p-RyR2, p-CaMKII, K_v11.1, K_ir2.3, K_Ca3.1, whereas the epicardial conduction velocity, I_Ca-L, I_to, and expression levels of Ca_v1.2, K_v1.5, K_v4.3 were decreased. Dox-treatment significantly improved the expression levels of K_v1.5, K_v4.3 and K_ir2.3 in CIH-D rats.</p><p><strong>Conclusion: </strong>CIH caused atrial electrical remodelling in our rats, which was improved by Dox treatment. These changes indicated the potential effects of Dox in AF.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navi-gating through tortuous anatomy.","authors":"Nikolaos Pyrpyris, Kyriakos Dimitriadis, Konstantinos Aznaouridis, Konstantinos Tsioufis","doi":"10.1080/00015385.2025.2500890","DOIUrl":"https://doi.org/10.1080/00015385.2025.2500890","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143951899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uric acid and cardiovascular risk in context: reflections on a regional study.","authors":"Ramazan Aslan, İsa Ardahanlı","doi":"10.1080/00015385.2025.2500891","DOIUrl":"https://doi.org/10.1080/00015385.2025.2500891","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accessory mitral valve tissue causing left ventricular outflow obstruction.","authors":"Damandeep Singh, Vineeta Ojha, Niraj Nirmal Pandey, Suad Akhtar, Aprateem Mukherjee, Sanjeev Kumar, Sivasubramanian Ramakrishnan","doi":"10.1080/00015385.2024.2424481","DOIUrl":"10.1080/00015385.2024.2424481","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"308-310"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The scalpel's dilemma: weighing the mortality risk of combined surgical aortic valve replacement and coronary artery bypass grafting.","authors":"Astrid Declercq, Vincent Floré, Nico Van de Veire","doi":"10.1080/00015385.2025.2476887","DOIUrl":"10.1080/00015385.2025.2476887","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"326-327"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left atrial myopathy in rheumatic mitral stenosis; three-dimensional and speckle tracking echocardiography study.","authors":"Hoda Abdelgawad, Darius Dufatanye, Mahmoud Shehata, Ingy Waheed, Noha Hesham, Judy Rizk, Rasha Abayazeed, Moustafa Dawood, Mohamed Ayman Abdel-Hay, Amr Zaki","doi":"10.1080/00015385.2025.2457180","DOIUrl":"10.1080/00015385.2025.2457180","url":null,"abstract":"<p><strong>Background: </strong>In developing countries, rheumatic mitral valve stenosis (MS) is still a problem and its progression leads to left atrial (LA) damage. Due to the complexity of the LA geometry, currently used techniques like antero-posterior dimension (LAD) and 2D echo derived LA volume (LAV) have several limitations that are corrected by 3D derived LA volumes in addition to functional evaluation.</p><p><strong>Purpose: </strong>To assess the LA functions using 2D speckle tracking echocardiography and 3D transthoracic echocardiography in patients with clinically significant MS in comparison to normal healthy subjects.</p><p><strong>Results: </strong>Fifty patients and 50 healthy controls were studied. Patients' mean age was 40.2 ± 8.8 years, the majority were female 45(81.8%). 3D indexed LA maximum (LAVmaxI) and minimum (LAVminI) volumes were significantly higher in MS than in the control group, whereas 3D LA EF was significantly lower in MS than in the control group (p 0.001). LA strain reservoir, conduit, and contraction parameters were significantly lower in the MS group than in the control group (<i>p</i> = 0.001). However, only 3D LAEF, 2D LASr, 2D LAScd, and 2D LASct showed a correlation with the mitral valve area with a <i>p</i> < 0.05, but 3D LAVmaxI and 3D LAVminI did not. Additionally, in the comparison of severe and very severe mitral stenosis subgroups, 3D LAVmaxI and 3D LAVminI did not show any statistically significant differences between the two groups, although 3D LAEF, 2D LASr, 2D LAScd, and 3D LASct showed significant difference between the two groups (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Left atrial functional and structural remodelling has been highlighted in patients with significant rheumatic MS. However, left atrial functional assessment by 3D echocardiography and 2D speckle tracking echocardiography correlate better with mitral valve area than conventional LA size measurements. Whether the functional assessment of the LA has an additive predictive value with regards to patient outcome needs to be interrogated.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"225-236"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary perspectives in cardiovascular medicine: imaging, interventions, and prognostic strategies.","authors":"Patrizio Lancellotti","doi":"10.1080/00015385.2025.2496029","DOIUrl":"https://doi.org/10.1080/00015385.2025.2496029","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":"80 3","pages":"209-212"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}