Acta cardiologica最新文献_第10页

Advancing strategies for valvular heart disease and pulmonary hypertension: insights and perspectives. 推进瓣膜性心脏病和肺动脉高压的策略：见解和观点。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2024-11-01 Epub Date: 2024-12-05 DOI: 10.1080/00015385.2024.2436769

Patrizio Lancellotti, Raluca Dulgheru

引用次数: 0

A new electrocardiographic parameter terminal D1S + D3R predicts right ventricular dilatation in acute pulmonary embolism. 一种新的心电参数终端 D1S + D3R 可预测急性肺栓塞的右心室扩张。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2024-11-01 Epub Date: 2024-09-17 DOI: 10.1080/00015385.2024.2396760

Funda Başyiğit, Oğuz Uçar, Emine Cansu Yücel, Nazlı Turan, Belma Yaman, Özcan Özdemir, Mustafa Mücahit Balcı, Hatice Tolunay

{"title":"A new electrocardiographic parameter terminal D1S + D3R predicts right ventricular dilatation in acute pulmonary embolism.","authors":"Funda Başyiğit, Oğuz Uçar, Emine Cansu Yücel, Nazlı Turan, Belma Yaman, Özcan Özdemir, Mustafa Mücahit Balcı, Hatice Tolunay","doi":"10.1080/00015385.2024.2396760","DOIUrl":"10.1080/00015385.2024.2396760","url":null,"abstract":"Objective: Right ventricular (RV) overload findings affect the risk classification and treatment approach in acute pulmonary embolism (APE). Recently, it was reported that a new electrocardiography (ECG) parameter, terminal D1S + D3R (T-D1S + D3R) pattern, supported the diagnosis of APE. We aim to search the relationship between T-D1S + D3R pattern and right ventricular dilatation (RVD) in APE.Methods: This single-centre, retrospective study was designed with patients aged > 18 years. We screened 267 patients who underwent transthoracic echocardiography (TTE) because of confirmed APE in our emergency department. This study included 72 patients with RVD and 139 patients without RVD [male 41.7%, median age 73,0 (20.8) years; 49.6% male, median age 64,0 (24.0) years]. We compared T-D1S + D3R between RVD (+) and RVD (-) groups.Results: We determined that RVD (+) group had more patients with the T-D1S + D3R parameter than RVD (-) group [51 (70.8%) vs. 25 (18.0%), p < 0.001]. In the univariate logistic regression analyses S1Q3T3, (in)complete right bundle branch block (RBBB), T-D1S + D3R, D3-V1 T wave inversion (TWI), V1-3/4 TWI, V1-3/4 ST-segment elevation, and frontal QRS-T [f(QRS-T)] angle predicted RVD, while T-D1S + D3R, V1-3/4 ST-segment elevation, and f(QRS-T) angle remained independent predictors of RVD in patients with APE.Conclusions: T-D1S + D3R, a new ECG parameter, was an independent predictor of RVD in patients with APE.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1021-1029"},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infective endocarditis following mitral transcatheter edge-to-edge repair. 二尖瓣经导管边缘对边缘修补术后感染性心内膜炎。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2024-11-01 Epub Date: 2024-08-27 DOI: 10.1080/00015385.2024.2390330

Tom Develtere, Stijn Lochy, Danièle Plein, Steven Droogmans, Xavier Galloo, Tom Carmeliet, Frederik H Verbrugge, Philippe Unger

引用次数: 0

A Belgian consensus on sotatercept for the treatment of pulmonary arterial hypertension. 比利时就索泰特受体治疗肺动脉高压达成共识。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2024-11-01 Epub Date: 2024-10-08 DOI: 10.1080/00015385.2024.2408130

Jean-Luc Vachiéry, Catharina Belge, Bjorn Cools, An Damen, Fabian Demeure, Michel De Pauw, Céline Dewachter, Daniel De Wolf, Laurence Gabriel, Laurent Godinas, Julien Guiot, Steven Haine, Mathias Leys, Marc Meysman, Anne-Catherine Pouleur, David Ruttens, Els Vandecasteele, Wendy Vansteenkiste, Thierry Weber, Gil Wirtz, Marion Delcroix

{"title":"A Belgian consensus on sotatercept for the treatment of pulmonary arterial hypertension.","authors":"Jean-Luc Vachiéry, Catharina Belge, Bjorn Cools, An Damen, Fabian Demeure, Michel De Pauw, Céline Dewachter, Daniel De Wolf, Laurence Gabriel, Laurent Godinas, Julien Guiot, Steven Haine, Mathias Leys, Marc Meysman, Anne-Catherine Pouleur, David Ruttens, Els Vandecasteele, Wendy Vansteenkiste, Thierry Weber, Gil Wirtz, Marion Delcroix","doi":"10.1080/00015385.2024.2408130","DOIUrl":"10.1080/00015385.2024.2408130","url":null,"abstract":"Pulmonary arterial hypertension (PAH) is a rare disease affecting the small pulmonary vessels, ultimately leading to right ventricular failure and death. Current treatment options target three different pathways (endothelin, nitric oxide/cGMP and prostacyclin pathways). Despite their demonstrated efficacy, these therapies (commonly used in combination) do not cure the disease which is why novel pathways beyond the traditional 'big three' are being developed. Sotatercept is a ligand trap for multiple proteins within the TGF-β superfamily that was recently approved in the US for the treatment of PAH. Unlike currently available therapies, sotatercept has the potential to act as an anti-remodelling agent rather than a vasodilator. The safety and efficacy of subcutaneous (SC) sotatercept have been established in two multicentre, placebo-controlled randomised-controlled trials. The compound has been shown to consistently improve a variety of measurable endpoints, including exercise capacity, haemodynamics, quality of life and delay of clinical worsening. The drug appears to have an acceptable safety profile, although it is associated with an increased risk in developing telangiectasia and biological changes affecting platelet counts and haemoglobin. This study reviews the current evidence on SC sotatercept and provides a Belgian perspective on its place in the future treatment strategy for PAH.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"978-983"},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of non-invasive oscillometric method to detect aortic stiffness in patients with subclinical hypothyroidism. 用无创示波法检测亚临床甲状腺功能减退症患者主动脉僵硬度的作用。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2024-11-01 Epub Date: 2024-07-08 DOI: 10.1080/00015385.2024.2375486

Ali Evsen, Mustafa Oylumlu

{"title":"The role of non-invasive oscillometric method to detect aortic stiffness in patients with subclinical hypothyroidism.","authors":"Ali Evsen, Mustafa Oylumlu","doi":"10.1080/00015385.2024.2375486","DOIUrl":"10.1080/00015385.2024.2375486","url":null,"abstract":"Introduction: Subclinical hypothyroidism (SCH) is a biochemical condition that is diagnosed when peripheral free thyroid hormone levels are within normal reference laboratory range but serum thyroid-stimulating hormone (TSH) levels are mildly elevated. The aim of this study was to investigate the relationship between SCH and arterial stiffness using two different non-invasive methods, including echocardiography and oscillometric arteriography.Material and methods: The study included 33 newly diagnosed SCH patients and 34 age- and gender-matched healthy controls. Systolic and diastolic diameters and elastic parameters of the aorta were calculated by 2D Transthoracic echocardiography (TTE). Central blood pressure and aortic stiffness values of patient groups were measured noninvasively from the brachial artery using Mobil-O-Graph arteriography. Pulse wave velocity (PWV) and augmentation index (AIx) were used as arterial stiffness indicators.Results: There was no significant difference between SCH and control groups with regard to age, gender, and body mass index (BMI). Aortic strain and aortic distensibility, were significantly lower in the SCH group than in the control group (p < 0.001). PWV and AIx which measured by Mobil-O-Graph arteriography were found to be significantly higher in the subclinical hypothyroid group compared to the control group (p < 0.05).Conclusion: Aortic stiffness assessed by TTE and Mobil-O-Graph arteriography deteriorated in patients with SCH after excluding other cardiovascular risk factors. The assessment of aortic stiffness by the oscillometric method was easy and useful for widespread clinical use.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1004-1010"},"PeriodicalIF":2.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141553986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Papillary fibroelastomas of tricuspid valve. 三尖瓣乳头状纤维母细胞瘤

IF 2.1 4区医学

Acta cardiologica Pub Date : 2024-11-01 Epub Date: 2024-03-12 DOI: 10.1080/00015385.2024.2327139

Dandan Chen, Xiaojing Ma, Yafeng He, Shurui Xie, Juan Xia

引用次数: 0

Multimodality imaging for the diagnosis of right atrial capillary haemangioma. 诊断右心房毛细血管瘤的多模态成像。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2024-10-29 DOI: 10.1080/00015385.2024.2422147

Xinyu Li, Xiaojing Ma, Juan Xia

引用次数: 0

Coexisting bicuspid pulmonary and aortic valves. 肺动脉瓣和主动脉瓣双瓣并存。