Acta cardiologicaPub Date : 2024-09-10DOI: 10.1080/00015385.2024.2396767
Joke Devoldere, Steven Droogmans, Ward A. Heggermont, Emeline Van Craenenbroeck
{"title":"Implementation of guideline-directed medical therapy for heart failure patients with reduced ejection fraction in Belgium: a Delphi panel approach","authors":"Joke Devoldere, Steven Droogmans, Ward A. Heggermont, Emeline Van Craenenbroeck","doi":"10.1080/00015385.2024.2396767","DOIUrl":"https://doi.org/10.1080/00015385.2024.2396767","url":null,"abstract":"The 2021 European Society of Cardiology (ESC) guidelines recommended a shift from a traditional hierarchical treatment for heart failure with reduced ejection fraction (HFrEF) to a four-pillar medi...","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":"50 1","pages":"1-12"},"PeriodicalIF":1.6,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142192753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-09-03DOI: 10.1080/00015385.2024.2392315
Luigi Cappannoli, Ciro Pollio Benvenuto, Cosimo Oliva, Achille de Dominicis, Carlo Trani, Francesco Burzotta
{"title":"Percutaneous retrieval of a subcutaneous contraceptive device migrated in pulmonary circulation.","authors":"Luigi Cappannoli, Ciro Pollio Benvenuto, Cosimo Oliva, Achille de Dominicis, Carlo Trani, Francesco Burzotta","doi":"10.1080/00015385.2024.2392315","DOIUrl":"https://doi.org/10.1080/00015385.2024.2392315","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142118674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rare association of type II truncus arteriosus with type A interrupted aortic arch.","authors":"Damandeep Singh, Niraj Nirmal Pandey, Lamk Kadiyani, Sanjeev Kumar","doi":"10.1080/00015385.2024.2371577","DOIUrl":"10.1080/00015385.2024.2371577","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"844-845"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141454555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-09-01Epub Date: 2024-11-11DOI: 10.1080/00015385.2024.2421090
Patrizio Lancellotti, Orianne De La Brassinne Bonardeaux
{"title":"Biomarkers and inflammation in coronary artery disease: key insights.","authors":"Patrizio Lancellotti, Orianne De La Brassinne Bonardeaux","doi":"10.1080/00015385.2024.2421090","DOIUrl":"https://doi.org/10.1080/00015385.2024.2421090","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":"79 7","pages":"747-750"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-09-01Epub Date: 2024-05-21DOI: 10.1080/00015385.2024.2349828
José Nunes de Alencar
{"title":"The troponin trap: a deep dive into incorporation and feedback sanction biases in NSTEMI diagnoses.","authors":"José Nunes de Alencar","doi":"10.1080/00015385.2024.2349828","DOIUrl":"10.1080/00015385.2024.2349828","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"857-859"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141070199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-09-01Epub Date: 2024-03-21DOI: 10.1080/00015385.2024.2327141
Swasthi S Kumar, Deepa Sasikumar, Anoop Ayyappan, K M Krishnamoorthy, Baiju S Dharan
{"title":"ALCAPA - the great masquerader.","authors":"Swasthi S Kumar, Deepa Sasikumar, Anoop Ayyappan, K M Krishnamoorthy, Baiju S Dharan","doi":"10.1080/00015385.2024.2327141","DOIUrl":"10.1080/00015385.2024.2327141","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"841-843"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140178951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Truncus arteriosus with isolated origin of left subclavian artery from the pulmonary trunk.","authors":"Neeraj Kumar, Niraj Nirmal Pandey, Lamk Kadiyani, Sanjeev Kumar","doi":"10.1080/00015385.2023.2279413","DOIUrl":"10.1080/00015385.2023.2279413","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"837-838"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92152207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-09-01Epub Date: 2024-10-08DOI: 10.1080/00015385.2024.2409521
Lukas Duvillier, Carl Verhaege, Katrien M J Devreese, Sofie Gevaert, Harlinde Peperstraete
{"title":"Evaluation of the effects and plasma concentration of the platelet inhibitor ticagrelor, after crushed and non-crushed intake, after cardiac arrest and after semi-urgent coronary artery bypass surgery.","authors":"Lukas Duvillier, Carl Verhaege, Katrien M J Devreese, Sofie Gevaert, Harlinde Peperstraete","doi":"10.1080/00015385.2024.2409521","DOIUrl":"10.1080/00015385.2024.2409521","url":null,"abstract":"<p><strong>Background: </strong>Ticagrelor, used in acute coronary syndrome (ACS), can be administered via nasogastric tube when oral intake is impossible. We investigated platelet inhibition and pharmacokinetics in resuscitated ACS patients and those undergoing semi-urgent coronary artery bypass graft (CABG) surgery. Our study aimed to assess platelet inhibition with use of the Platelet Function Analyser (PFA) and measured plasma concentrations of ticagrelor and its active metabolite in these ACS patients.</p><p><strong>Methods: </strong>We included resuscitated cardiac arrest patients (STEMI/NSTEMI) and semi-urgent CABG patients. Crushed ticagrelor tablets were administered using a nasogastric tube. PFA closure time (CT) was determined with CT longer than 113 s as reference range. Plasma concentrations of ticagrelor and its active metabolite were measured after protein precipitation, by using liquid chromatography with mass spectrometry detection.</p><p><strong>Results: </strong>In 20 resuscitated patients, 89% showed platelet inhibition at 24 h and 92% at day 4. For semi-urgent CABG patients, 85% exhibited platelet inhibition at 24 h and 84% at day 4. For ticagrelor in resuscitated patients, the median time to peak plasma concentration (Tmax) was 100 h [8; 100] for a median maximal concentration (Cmax) of 615.5 ng/mL [217.5; 1385.0]. For AR-C124910XX median Tmax was 100 h [8; 100] for a Cmax of 131.0 ng/mL [52.1; 177.7]. Among 20 patients undergoing semi-urgent CABG, Tmax for ticagrelor was 100 h [100; 100] for a median Cmax of 857.0 ng/ml [496.8; 1157.5]. For AR-C124910XX, median Tmax was 100 h [43; 100] for a Cmax of 251.0 ng/ml [173.0; 396.5].</p><p><strong>Conclusion: </strong>Crushed ticagrelor via nasogastric tube achieved targeted platelet inhibition. Pharmacokinetics aligned with previous studies.EudraCT number: 2013-004191-35; Study protocol code: AGO/2013/011; EC/2014/1061; ClinicalTrial.gov identifier: NCT02341729.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"805-812"},"PeriodicalIF":2.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142387217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}