Acta cardiologicaPub Date : 2024-12-01Epub Date: 2024-12-03DOI: 10.1080/00015385.2024.2432693
Yuyuan Shu, Si-Qi Lyu, Jiangshan Tan, Han Zhang, Yimeng Wang, Lulu Wang, Yijing Xin, Yanmin Yang
{"title":"Sex differences in patients with atrial fibrillation and acute coronary syndrome or undergoing PCI: a real-world study.","authors":"Yuyuan Shu, Si-Qi Lyu, Jiangshan Tan, Han Zhang, Yimeng Wang, Lulu Wang, Yijing Xin, Yanmin Yang","doi":"10.1080/00015385.2024.2432693","DOIUrl":"10.1080/00015385.2024.2432693","url":null,"abstract":"<p><strong>Background: </strong>In patients with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI), female patients have a worse short-term prognosis than male patients has been consistently concluded in many studies. However, the impact of sex differences on long-term prognosis remains uncertain. Additionally, women are underrepresented in clinical trials exploring optimal antithrombotic strategies in patients with atrial fibrillation (AF) and ACS or PCI. To bridge this gap, this study aimed to investigate sex differences in clinical characteristics, treatment, and long-term clinical outcomes in patients with AF and ACS or PCI.</p><p><strong>Patients and methods: </strong>This study included a total of 1237 patients with AF and ACS and 539 patients with AF and stable coronary artery disease (SCAD) who underwent PCI at the Fuwai Hospital of the Chinese Academy of Medical Sciences from January 2017 to December 2019. Patients were followed up until the end of 2021 to observe the occurrence of major adverse cardiovascular events (MACE). The relationship between sex and MACE was evaluated using Cox regression models and Kaplan-Meier's survival curves.</p><p><strong>Results: </strong>In patients with AF and ACS, multivariable COX regression analysis revealed that female patients were independently associated with a higher risk of MACE (HR = 1.45, 95% CI 1.11-1.89, <i>p</i> = .006). However, in AF patients with SCAD who underwent PCI, the analysis showed that female patients were not independently associated with MACE risk (HR = 1.12, 95% CI 0.62-2.03, <i>p</i> = .717).</p><p><strong>Conclusions: </strong>In patients with AF and ACS, females have a significantly higher risk of long-term MACE compared to males. However, among patients with AF and SCAD who underwent PCI, there was no significant difference in long-term MACE risk between males and females.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1119-1132"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Left ventricular myocardial deformation in patients on maintenance haemodialysis.","authors":"Hardeep Kaur Grewal, Manish Jain, Rakesh Bhat, Ashish Nandwani, Dinesh Yadav, Shyam Bansal, Dinesh Bansal, Manish Bansal","doi":"10.1080/00015385.2024.2424488","DOIUrl":"10.1080/00015385.2024.2424488","url":null,"abstract":"<p><strong>Background: </strong>Patients with chronic kidney disease (CKD) undergoing maintenance haemodialysis (MHD) develop several abnormalities of left ventricular (LV) structure and function. Speckle-tracking echocardiography permits compressive assessment of LV myocardial deformation. Previous studies involving CKD patients have shown a significant reduction in LV global longitudinal strain (GLS) with strong prognostic implications. However, the other components of LV deformation have not been fully elucidated.</p><p><strong>Methods: </strong>A total of 90 CKD patients undergoing MHD (mean age 41.3 ± 12.5 years, 80% men) were compared with 45 apparently healthy age- and gender-matched controls.</p><p><strong>Results: </strong>The CKD patients had a high prevalence (77.8% patients) of LV hypertrophy. They also had a significantly elevated ratio of early diastolic mitral inflow velocity to annular velocity (12.1 ± 4.6 vs. 7.1 ± 1.5, <i>p</i> < .001) indicating a high prevalence of LV diastolic dysfunction. LV ejection fraction (LVEF) was the same between the two groups, but the CKD patients had significantly impaired LVGLS (-17.8 ± 3.9 vs. -20.8 ± 2.6, <i>p</i> < .001), global circumferential strain (-14.0 ± 3.5 vs. -16.1 ± 3.4, <i>p</i> = .001), LV apical rotation (6.6 ± 4.7° vs. 8.8 ± 4.0°, <i>p</i> = .008) and LV twist (12.8 ± 6.1° vs. 15.0 ± 6.0°, <i>p</i> = .037). There was no difference in the global radial strain between the two groups.</p><p><strong>Conclusions: </strong>The present study shows that CKD patients on MHD have significantly impaired LV longitudinal and circumferential mechanics despite preserved LVEF. The prognostic implications of reduced LVGLS have already been demonstrated previously. Future studies are needed to assess the prognostic implications of abnormal LV circumferential mechanics as well as their reversibility following renal transplant.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1094-1100"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-12-01Epub Date: 2023-05-11DOI: 10.1080/00015385.2023.2207927
Adrien Coquilhat, Elias Alhage
{"title":"Massive thrombus… not only in the pulmonary artery.","authors":"Adrien Coquilhat, Elias Alhage","doi":"10.1080/00015385.2023.2207927","DOIUrl":"10.1080/00015385.2023.2207927","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1133-1134"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9796501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-12-01Epub Date: 2023-10-17DOI: 10.1080/00015385.2023.2268427
Xiang Zhou, Laichun Song, Wenqiang Sun, Youping Chen, Liang Tao
{"title":"A rare case of primary right atrial teratoma in an adult.","authors":"Xiang Zhou, Laichun Song, Wenqiang Sun, Youping Chen, Liang Tao","doi":"10.1080/00015385.2023.2268427","DOIUrl":"10.1080/00015385.2023.2268427","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1141-1142"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41231531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-12-01Epub Date: 2024-10-07DOI: 10.1080/00015385.2024.2408131
Cédric Willemse, G Vermeersch, P Hollering
{"title":"Differential diagnosis of mediastinal cysts: a case series.","authors":"Cédric Willemse, G Vermeersch, P Hollering","doi":"10.1080/00015385.2024.2408131","DOIUrl":"10.1080/00015385.2024.2408131","url":null,"abstract":"<p><strong>Background: </strong>Mediastinal cysts are common mediastinal lesions in which diagnostic and therapeutic choices are not always unambiguously presented. Usually, these cysts are asymptomatic and detected by coincidence. The question remains whether, if symptoms are present, the cyst is responsible and whether it should be treated. Unfortunately, there is a lack of standardised guidelines concerning diagnostic, therapeutic management and follow-up.</p><p><strong>Case summary: </strong>In this case series we reported five patients with mediastinal cysts. All patients received a thoracic CT during the initial diagnostic assessment. Four out of five patients were symptomatic and were surgically treated during a uniportal video-assisted thoracoscopy. One patient was asymptomatic and receives a biennial follow-up. Most often, histopathological examination confirmed the already presumed type of non-neoplastic mediastinal cyst based on anatomical location and tissue characteristics (one thymic cyst, one bronchogenic cyst and two pericardial cysts). Except for one patient, all surgically treated patients experienced improvement in symptoms.</p><p><strong>Conclusion: </strong>Regarding diagnosis and treatment of this entity, a systematic approach in accordance with the most recent literature is important. The diagnosis can only be confirmed on histopathological examination, but several imaging techniques, with contrast-enhanced CT as the first-choice technique, could guide the differential diagnosis. In large, symptomatic cysts or present potential malignant features, surgical removal is indicated. This case series encourages further substantial research concerning the selection and timing of therapy.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1087-1093"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142379847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-12-01Epub Date: 2024-05-09DOI: 10.1080/00015385.2024.2336346
Ying Li, Ye Zhu, Xia Jiang, Cheng Tan, Kaiwei Li, Rui Shi, Han Nie
{"title":"Effects of weight loss on QTc in people with obesity: a systematic review and meta-analysis.","authors":"Ying Li, Ye Zhu, Xia Jiang, Cheng Tan, Kaiwei Li, Rui Shi, Han Nie","doi":"10.1080/00015385.2024.2336346","DOIUrl":"10.1080/00015385.2024.2336346","url":null,"abstract":"<p><strong>Background and aims: </strong>Overweight and obesity have been found to exhibit a statistically significant increase in corrected QT interval (QTc), a major contributing factor to sudden death. However, the influence of widely used weight loss strategies including diet, exercise, anti-obesity drugs, and bariatric surgery on QTc remains inconsistent. Therefore, the present systematic review and meta-analysis aim to quantitatively analyse and evaluate the effect of weight loss on QTc in obese patients after diet control with exercise intervention and anti-obesity drugs, as well as bariatric surgery.</p><p><strong>Methods: </strong>Twenty randomised controlled trials (RCT) and observational studies were included in the meta-analysis on the effects of weight loss on QTc. The fixed-effects model was employed in the RCTs, and the random-effects model was employed due to the presence of statistical heterogeneity among observational studies. Subgroup analysis was conducted to understand the differences in distinct weight loss methods and follow-up time.</p><p><strong>Results: </strong>Overall, the QTc of people with obesity after weight loss was shorter than that before (mean difference (MD) = 21.97 ms, 95% confidence interval (CI) = 12.42, 31.52, <i>p</i> < .0001). Subgroup analysis restricted to seven included studies whose intervention was diet control with exercise showed a decrease of QTc with statistical significance (MD = 9.35 ms, 95%CI = 2.56, 37.54, <i>p</i> = .007). In the remaining 11 studies, bariatric surgery was the weight loss method. The results also showed a shortening of QTc after surgery, and the difference was statistically significant (MD = 29.04 ms, 95%CI = -16.46, 41.62, <i>p</i> < .00001). A statistically significant difference in QTc shortening at 6 months compared to pre-operation values was further observed (MD = -31.01 ms, 95%CI = -2.89, -59.12, <i>p</i> = .03). The shortening of QTc at 12 months of follow-up was also significantly different from that before surgery (MD = 36.47 ms, 95%CI = 14.17, 58.78, <i>p</i> < .00001). Moreover, the differences became more pronounced as the follow-up time extended.</p><p><strong>Conclusions: </strong>We demonstrate that weight loss links to a shortened QTc, without considering the means of weight loss. Bariatric surgery has been found to result in a greater reduction in QTc.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1071-1086"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140896850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-12-01Epub Date: 2024-09-17DOI: 10.1080/00015385.2024.2404769
Francois De Greef, Nicolas Selvais, Adel Aminian
{"title":"Effects of interatrial septal shunt repair on disabling migraine 'Time passes, the question remains'.","authors":"Francois De Greef, Nicolas Selvais, Adel Aminian","doi":"10.1080/00015385.2024.2404769","DOIUrl":"10.1080/00015385.2024.2404769","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1157-1158"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2024-12-01Epub Date: 2024-01-30DOI: 10.1080/00015385.2024.2308431
Marco Parillo, Domenico De Stefano, Irene Maisto, Bruno Beomonte Zobel
{"title":"Cardiac computed tomography findings in a rare case of cardiac perforation due to pacemaker lead.","authors":"Marco Parillo, Domenico De Stefano, Irene Maisto, Bruno Beomonte Zobel","doi":"10.1080/00015385.2024.2308431","DOIUrl":"10.1080/00015385.2024.2308431","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1153-1154"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139574909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}