Acta cardiologica最新文献_第7页

Causal correlation between gut microbiota and stable angina pectoris: a two-sample Mendelian randomisation study. 肠道菌群与稳定性心绞痛之间的因果关系：一项双样本孟德尔随机研究。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-07-21 DOI: 10.1080/00015385.2025.2515320

Chengji Zhou, Jiameng Jia, Yimin Du, Tailuan Peng, Qiang Zheng

{"title":"Causal correlation between gut microbiota and stable angina pectoris: a two-sample Mendelian randomisation study.","authors":"Chengji Zhou, Jiameng Jia, Yimin Du, Tailuan Peng, Qiang Zheng","doi":"10.1080/00015385.2025.2515320","DOIUrl":"https://doi.org/10.1080/00015385.2025.2515320","url":null,"abstract":"Background: Patients with stable angina pectoris (SAP) are usually accompanied by gut microbiota (GM) imbalance, but whether this is a causal association is yet unclear.Methods: The present study used the summary data of the open genome-wide association study (GWAS) to conduct two-sample Mendelian randomisation (MR) to test the causal association between GM and SAP. Finally, functional maps and annotations from GWASs were used to determine the biological functions of the genes.Results: MR analysis found that Ruminococcus 2 was significantly positively associated with the risk of SAP. For every unit increase in Ruminococcus 2, the relative risk of SAP increased by 22.3% (p = 4.55E - 04, Bonferroni p = 6.82E - 03). Firmicutes, Odoribacter, Actinomyces, Veillonellaceae, Eisenbergiella, and Ruminococcus gauvreauii groups may be positively related to the risk of SAP, while Proteobacteria, Methanobacteriaceae, Euryarchaeota, Verrucomicrobia, Ruminiclostridium 9, and Anaerofilum may be negatively associated with the risk of SAP. Nonetheless, the specific role of SNPs gene enrichment analysis results needs further investigation.Conclusions: The findings of this study suggest a causal relationship between GM and SAP. The discovery of GM and its gene biological functions may offer insights for preventing and treating SAP.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-10"},"PeriodicalIF":2.1,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complete heart block due to extensive leukemic endocardial infiltration. 广泛白血病心内膜浸润引起的完全性心脏传导阻滞。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-07-14 DOI: 10.1080/00015385.2025.2530285

Cameron Haskoy, Nils De Marneffe, Patrizio Lancellotti

引用次数: 0

Inflammatory cardiomyopathy: a comprehensive review of biomarkers and future therapeutic perspectives. 炎症性心肌病：生物标志物和未来治疗前景的综合综述。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-07-06 DOI: 10.1080/00015385.2025.2528001

Nimisha Chitroda, Arwa Mithaiwala, Angel Godad

{"title":"Inflammatory cardiomyopathy: a comprehensive review of biomarkers and future therapeutic perspectives.","authors":"Nimisha Chitroda, Arwa Mithaiwala, Angel Godad","doi":"10.1080/00015385.2025.2528001","DOIUrl":"https://doi.org/10.1080/00015385.2025.2528001","url":null,"abstract":"Myocardial inflammation is a hallmark of inflammatory cardiomyopathy, a heart condition that impairs heart function. This condition encompasses a variety of aetiologies including viral infections, autoimmune disorder, toxin exposures, etc which collectively contribute to its heterogeneity. The classification of ICM varies including Hypertrophic, inflammatory, dilated, left ventricular non-compaction, diabetic, restrictive, etc which are its notable subtypes central to the progression of ICM are inflammatory mechanisms such as cytokine release, immune cell activates, activation of Signalling pathways like NF-κB, NLRP3 inflammasome, etc. These pathways exacerbate inflammatory response & cause cardiac damage. Biomarkers like cardiac troponin- c reactive protein, etc are used for diagnosis &prognosis however, they possess some limitations including specificity & predictive value complicating their chemical utility. Emerging therapies after promising avenues for improved treatment outcomes clinical implications understand the necessity of timely diagnosis & personalised treatment approaches, emphasis the balance between immunosuppression & antiviral therapy. Future perspectives emphasise integrating omics technologies & advanced imaging for more precise diagnostics, alongside developing innovative treatments aimed at modulating inflammation without compromising cardiac function ongoing CT & research on novel molecular targets will likely expand the therapeutic landscape, offering hope for better management & prognosis of ICM.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-15"},"PeriodicalIF":2.1,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The protective role of dapagliflozin on the noreflow phenomenon in type 2 diabetic patients with acute coronary syndrome undergoing percutaneous coronary intervention. 达格列净对2型糖尿病合并急性冠脉综合征患者经皮冠状动脉介入治疗后无回流现象的保护作用

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-07-01 Epub Date: 2025-05-27 DOI: 10.1080/00015385.2025.2511523

Cemal Köseoğlu, Ali Çoner, Can Ramazan Öncel

引用次数: 0

Rethinking methodologies in nocturnal blood pressure dipping research: insights from Lopez et al. 重新思考夜间血压下降研究的方法：来自Lopez等人的见解。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-07-01 Epub Date: 2025-01-30 DOI: 10.1080/00015385.2025.2453799

Arthur Sá Ferreira, Gabriel Parisotto

引用次数: 0

Advanced image reconstruction algorithm keeps reducing the radiation dose needed for CT calcium scoring. 先进的图像重建算法不断降低CT钙评分所需的辐射剂量。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-07-01 Epub Date: 2025-04-14 DOI: 10.1080/00015385.2025.2490398

Alain Nchimi

引用次数: 0

Cardiac arrest in a young female: the potentially fatal synergy of selective serotonin reuptake inhibitors and recreational marijuana use. 年轻女性心脏骤停：选择性血清素再摄取抑制剂和娱乐性大麻使用的潜在致命协同作用。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-07-01 Epub Date: 2025-06-04 DOI: 10.1080/00015385.2025.2500889

Cristian Castillo-Rodriguez, Jesus Davalos, Douglas Andre Salguero-Lopez, Sameh Girgis

引用次数: 0

Urgent cardiac surgery for aortic dissection in a 3-year-old: the role of 3D printing. 3 岁儿童主动脉夹层的紧急心脏手术：3D 打印的作用。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-07-01 Epub Date: 2024-08-29 DOI: 10.1080/00015385.2024.2396747

Jie Wang, Chen Chen, Ping Hu, Yu-Hang Wang, Juan Xia

引用次数: 0

Prediction of cardiovascular disease using blood pressure indices: more than just the level? 利用血压指标预测心血管疾病：不仅仅是水平？

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-07-01 Epub Date: 2025-03-24 DOI: 10.1080/00015385.2025.2480940

Guy De Backer

引用次数: 0

Comparison of postoperative pain and quality of life between left anterior thoracotomy and median sternotomy off-pump coronary artery bypass surgery in multivessel coronary revascularization: a retrospective study of a case series of 356 consecutive patients. 多支冠脉重建术中左前开胸术与胸骨正中开胸术非泵送冠状动脉搭桥术术后疼痛和生活质量的比较：一项连续356例患者的回顾性研究。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-07-01 Epub Date: 2025-04-16 DOI: 10.1080/00015385.2025.2491152

Xiujun Chen, Yong Lin, Liangwan Chen, Xiaofu Dai, Zhiqin Lin

{"title":"Comparison of postoperative pain and quality of life between left anterior thoracotomy and median sternotomy off-pump coronary artery bypass surgery in multivessel coronary revascularization: a retrospective study of a case series of 356 consecutive patients.","authors":"Xiujun Chen, Yong Lin, Liangwan Chen, Xiaofu Dai, Zhiqin Lin","doi":"10.1080/00015385.2025.2491152","DOIUrl":"10.1080/00015385.2025.2491152","url":null,"abstract":"Background: This study compared post-operative pain and quality of life (QoL) between left anterior thoracotomy (LAT) and median sternotomy (MS) in off-pump coronary artery bypass grafting (OPCAB). LAT is a less invasive alternative to MS for the treatment of advanced coronary artery disease.Methods: This retrospective study analysed 356 patients who underwent OPCAB for multivessel revascularization between January 2018 and April 2023. Patients were divided into LAT (n = 169) and MS (n = 187) groups. Postoperative pain was measured using a Visual Analog Scale (VAS). QoL was assessed using the Short Form-36 (SF-36) questionnaire preoperatively and postoperatively.Results: Patients with LAT had significantly lower pain scores on postoperative days 1, 3, and 7 (p < 0.001) than those with MS. LAT was associated with shorter ICU and hospital stay (p = 0.011 and p < 0.001, respectively). The QoL scores for physical domains were higher in the LAT group at 1 and 3 months post-surgery (p < 0.01). No significant differences were observed in the mental health domains between groups.Conclusions: LAT for multivessel OPCAB is associated with reduced postoperative pain, shorter hospital stay, and improved early QoL, particularly in physical domains, compared to MS. These findings suggest that LAT is a preferable option for suitable patients, promoting faster recovery and better early postoperative outcomes.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"487-497"},"PeriodicalIF":2.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143951974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0