Acta cardiologica最新文献

{"title":"Bedtime vs. morning aspirin intake on the diurnal variability of blood pressure and platelet aggregation for the prevention of coronary artery diseases: a systematic review and meta-analysis.","authors":"Alina Ghazou, Mayar El-Haddad, Amany Abdelaziz Hasan, Muhammad Ashraf Saleh, Tamer Ahmed Mahmoud, Abderrazzak Elomari, Manar Alaa Mabrouk, Mostafa AbdulSattar, Aya Abdul Fattah Taha","doi":"10.1080/00015385.2025.2471654","DOIUrl":"https://doi.org/10.1080/00015385.2025.2471654","url":null,"abstract":"<p><strong>Purpose: </strong>Low-dose aspirin had been widely used for secondary prevention of cardiovascular disease. Chronopharmacology of arterial hypertension and platelet aggregation impacts the long-term thromboembolic risk in patients with cardiovascular disease. Therefore, clinical studies have proposed optimising aspirin dosing time. Therefore, the aim of this study is to investigate the effect of timing of administration of low dose aspirin on the mean blood pressure profile and platelet aggregation for primary and secondary prevention of cardiovascular disease.</p><p><strong>Methods: </strong>The literature search included PubMed, Scopus, Web of Science, and Cochrane CENTRAL. The identification of included randomised controlled trials (RCTs) followed a systematic literature review (SLR) in accordance with the guidelines and recommendations of The Cochrane Collaboration. RCTs on the effect of aspirin intake at different times of the day on blood pressure and platelet aggregation in adults with coronary arterial disease or arterial hypertension for primary or secondary prevention were included.</p><p><strong>Results: </strong>Meta-analysis included 11 RCTs out of 6495 studies. In terms of patients' characteristics, the overall mean age was 52.7, and 65% of the patients were men. The pooled mean differences of systolic and diastolic blood pressure were significant in the bedtime group in 'prehypertension and untreated hypertension' subgroup (MD = -8.20, 95% CI [-9.80, -6.61], MD = -4.02, 95% CI [-5.94, -2.11]; respectively) while no significant difference was seen in the 'treated hypertension and CVD' subgroup in both SBP and DBP (MD = -0.08, 95% CI [-2.65, 2.5], MD = -0.46, 95% CI [-2.20, 1.28]; respectively). The included studies demonstrating the effect of bedtime aspirin on platelet aggregation showed a significant reduction in platelet aggregation favouring the bedtime group with a mean difference of -21.15, 95% Cl [-32.78, -9.53].</p><p><strong>Conclusion: </strong>The study shows an additional antihypertensive benefit of bedtime aspirin intake in the prehypertension and untreated hypertension groups, which may provide a positive long-term impact on cardiovascular risk in hypertensive patients. Moreover, the study revealed an additional benefit of bedtime aspirin intake on platelet aggregation, particularly in the morning hours when most thromboembolic events were found to occur.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracing the source: suspicious right atrial mass.","authors":"Jiao Peng, Dandan Chen, Xiaojing Ma, Yafeng He, Juan Xia","doi":"10.1080/00015385.2025.2476889","DOIUrl":"https://doi.org/10.1080/00015385.2025.2476889","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143584260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Access to implantable cardioverter defibrillator therapy within and across countries: the barriers still persist.","authors":"Jacopo Francesco Imberti, Alberto Fisce, Giuseppe Boriani","doi":"10.1080/00015385.2025.2469000","DOIUrl":"https://doi.org/10.1080/00015385.2025.2469000","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-3"},"PeriodicalIF":2.1,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143539962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of a cardiac primary angiosarcoma.","authors":"Francesca Cortese, Luisiana Stolfi, Gianpaolo D' Addeo, Marco Fabio Costantino","doi":"10.1080/00015385.2025.2471652","DOIUrl":"https://doi.org/10.1080/00015385.2025.2471652","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1"},"PeriodicalIF":2.1,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the prognostic significance of platelet-to-lymphocyte ratio (PLR) for coronary artery lesions in Kawasaki disease.","authors":"Tiantuo Huang, Qi Peng, Yue Cao, Xiaochen Fan","doi":"10.1080/00015385.2025.2471656","DOIUrl":"https://doi.org/10.1080/00015385.2025.2471656","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to examine the correlation between the platelet-to-lymphocyte ratio (PLR) and coronary artery lesions (CALs) in individuals diagnosed with Kawasaki disease (KD) and to evaluate its prognostic significance.</p><p><strong>Methods: </strong>Our study entailed a detailed retrospective examination and analysis of clinical records for patients diagnosed with KD at the First Affiliated Hospital of Anhui Medical University from January 2017 to January 2023. In our methodological approach, we applied various statistical techniques - including univariate analyses, binary logistic regression, and receiver operating characteristic (ROC) curve analysis - to meticulously assess the relationship between the PLR and the incidence of CALs in this patient cohort. Our objective was to elucidate potential predictive markers for CALs development in KD patients, thereby contributing valuable insights into the prognosis and management of this condition.</p><p><strong>Results: </strong>In the conducted research, a total of 364 patients were analysed, among which 63 individuals (17.3%) exhibited CALs upon admission. Through the application of binary logistic regression analysis, our findings underscored PLR as a statistically significant predictor for the presence of CALs. Furthermore, the ROC curve analysis demonstrated an AUC (area under the curve) value of 0.707 (95%CI 0.641-0.772, <i>p</i> < .001) for the prognostic capacity of PLR concerning CALs.</p><p><strong>Conclusions: </strong>The outcomes of our investigation indicate that PLR acts as a significant risk indicator for CALs. Such insights pave the way for improved risk stratification and potentially guide therapeutic decision-making in patients with KD.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-7"},"PeriodicalIF":2.1,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First-in-man concomitant mitral transcatheter edge-to-edge repair and atrial fibrillation ablation.","authors":"Kyriakos Dimitriadis, Stergios Soulaidopoulos, Nikolaos Pyrpyris, Eirini Beneki, Dimitrios Tsiachris, Konstantinos Aznaouridis, Konstantina Aggeli, Konstantinos Tsioufis","doi":"10.1080/00015385.2025.2471651","DOIUrl":"https://doi.org/10.1080/00015385.2025.2471651","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clonal haematopoiesis of indeterminate potential and risk of atrial fibrillation.","authors":"Paschalis Karakasis, Eleftheria Lefkou, Dimitrios Patoulias, Nikolaos Fragakis","doi":"10.1080/00015385.2025.2471655","DOIUrl":"https://doi.org/10.1080/00015385.2025.2471655","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143497581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The intriguing relationships between atrial fibrillation and heart failure: insights from cardiac implantable electronic devices.","authors":"Davide Antonio Mei, Matteo Martella, Giuseppe Boriani","doi":"10.1080/00015385.2025.2469001","DOIUrl":"https://doi.org/10.1080/00015385.2025.2469001","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-3"},"PeriodicalIF":2.1,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143475918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant abdominal aortic aneurysm.","authors":"Sam Mirzaee, Andrei-Dumitru Margulescu","doi":"10.1080/00015385.2025.2467004","DOIUrl":"https://doi.org/10.1080/00015385.2025.2467004","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1"},"PeriodicalIF":2.1,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Office white-coat effect tail and long-term cardiovascular risks in 60-year follow-up of the European cohorts of the Seven Countries Study.","authors":"Xavier Humbert, Andry Rabiaza, Anthony Kafatos, Paolo Piras, Hanna Tolonen, Paolo-Emilio Puddu","doi":"10.1080/00015385.2025.2467006","DOIUrl":"https://doi.org/10.1080/00015385.2025.2467006","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to determine whether the office white-coat effect tail (OWCET), defined as decreasing of SBP ≥10 mmHg in multiple office systolic blood pressure measures, predicts major long-term fatal events in the nearly extinct European cohorts of the Seven Country Study (ECSCS).</p><p><strong>Material and methods: </strong>In the present analysis, 4,937 men (49 ± 5 years) were included. All-cause mortality and specific mortalities [cardiovascular mortality (CVD) including stroke, coronary heart disease (CHD) death as well as heart disease of uncertain aetiology (HDUE)] were considered using Cox models. Also non-CVD deaths were studied by Fine-Gray competing risk analysis.</p><p><strong>Results: </strong>At inclusion, subjects with OWCET were significantly more hypertensive. After 60-year follow-up, OWCET was not associated with risk of both CVD [aHR: 0.95 (95% CI: 0.82-1.03), <i>p</i> = 0.5] and all-cause death [aHR: 0.92 (95% CI: 0.82-1.03), <i>p</i> = 0.16] independently of traditional risk factors (age, SBP, BMI, total cholesterol and cigarettes) in ECSCS. Same results were found for Northern and Southern Europe cohorts of ECSCS concerning CVD death [aHR: 0.98 (95% CI: 0.76-1.26), <i>p</i> = 0.85 and aHR: 0.95 (95% CI: 0.74-1.20), <i>p</i> = 0.66] and all-cause death, respectively [aHR: 0.90 (95% CI: 0.75-1.07), <i>p</i> = 0.23 and aHR: 0.93 (95% CI: 0.79-1.09), <i>p</i> = 0.38].</p><p><strong>Conclusions: </strong>In a general population of men, OWCET is not associated to CVD or non-CVD and all-cause mortality and consequently cannot improve stratification of long-term CVD risks in ECSCS.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-8"},"PeriodicalIF":2.1,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}