Acta cardiologica最新文献_第2页

Association of the 'Life's Essential 8' with FeNO and all-cause mortality: a population-based study in U.S. adults. “生命必需的8项”与FeNO和全因死亡率的关系：一项基于美国成年人的人群研究。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-05-01 Epub Date: 2025-03-24 DOI: 10.1080/00015385.2025.2480960

Kai Li, Jie Feng, Leilei Han, Yanqing Wu

{"title":"Association of the 'Life's Essential 8' with FeNO and all-cause mortality: a population-based study in U.S. adults.","authors":"Kai Li, Jie Feng, Leilei Han, Yanqing Wu","doi":"10.1080/00015385.2025.2480960","DOIUrl":"10.1080/00015385.2025.2480960","url":null,"abstract":"Background: The 'Life's Essential 8' (LE8), a recent framework introduced by the American Heart Association (AHA), refines and expands the concept of wellness, with a particular emphasis on promoting cardiovascular health. The fractional exhaled nitric oxide (FeNO) score, a non-invasive and easily obtainable biomarker, offers a convenient method for evaluating respiratory conditions such as asthma. While both LE8 and FeNO represent emerging and widely recognised indicators of health, research exploring their interrelationship remains limited. This study aims to examine the associations between LE8, FeNO, and all-cause mortality.Methods: A total of 14,293 eligible participants, aged ≥18 years, were enrolled from the National Health and Nutrition Examination Survey (NHANES) database spanning 2007-2012. This observational cohort study integrated baseline NHANES data with mortality records from the U.S. National Death Index through 2021. To assess the association between LE8 and FeNO, we employed multiple linear regression models, both with and without adjustments for demographic factors and health-related practices. Additionally, these data were utilised to explore the relationships between various health determinants and all-cause mortality.Results: In this observational analysis, we found that an increase in the LE8 score was positively associated with elevated FeNO levels, a marker implicated in immune responses to respiratory diseases. Furthermore, higher LE8 scores were inversely associated with survival risk in the population, suggesting a potential protective effect on survival in the studied population.Conclusions: Our findings suggest that primary and tertiary prevention efforts to promote cardiovascular health should be strengthened, especially those targeting unhealthy factors and behaviours to improve cardiorespiratory fitness and reduce survival risk.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"245-253"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

René Gerónimo Favaloro (1923-2000): the challenging dream of a heart surgeon. ren<s:1> Gerónimo法瓦洛罗（1923-2000）：一个心脏外科医生具有挑战性的梦想。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-05-01 Epub Date: 2025-01-09 DOI: 10.1080/00015385.2024.2448866

Hernan Gonzalo Valdes-Socin, Vincent Tchana-Sato

引用次数: 0

Cardiac 'quartet': a rare case of quadricuspid aortic valve combined with ascending aortic aneurysm. 心脏“四重奏”：罕见的四尖瓣主动脉瓣合并升主动脉瘤1例。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-05-01 Epub Date: 2025-03-31 DOI: 10.1080/00015385.2025.2484859

Mengqi Tang, Juan Xia, Yafeng He, Yanling Xue, Zifan Wu, Xiaojing Ma

引用次数: 0

Prostaglandin G/H synthase 1 promotes thrombosis in atrial fibrillation through modulation of platelet activation, macrophage infiltration, inflammation, and autophagy inhibition. 前列腺素G/H合成酶1通过调节血小板活化、巨噬细胞浸润、炎症和自噬抑制促进房颤血栓形成。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-05-01 Epub Date: 2025-02-18 DOI: 10.1080/00015385.2025.2467009

Hao Bai, Guiyang Xi, Yangyang Cheng

{"title":"Prostaglandin G/H synthase 1 promotes thrombosis in atrial fibrillation through modulation of platelet activation, macrophage infiltration, inflammation, and autophagy inhibition.","authors":"Hao Bai, Guiyang Xi, Yangyang Cheng","doi":"10.1080/00015385.2025.2467009","DOIUrl":"10.1080/00015385.2025.2467009","url":null,"abstract":"Background: Prostaglandin G/H synthase 1 (PTGS1) is known to regulate platelet function and inflammation. However, its role in atrial fibrillation (AF)-related thrombosis is not well understood. This study investigates the role of PTGS1 in AF-associated thrombus formation and its underlying mechanisms.Methods: Left atrial appendage (LAA) tissues were collected from 48 patients undergoing valve replacement surgery, divided into three groups: sinus rhythm (SR), AF with thrombus [AF (+) T (+)], and AF without thrombus [AF (+) T (-)]. PTGS1 expression, platelet activation markers (MPA, sCD40L, and d-dimer), macrophage phenotypes (M1 and M2), inflammatory cytokines (IL-1β, TNF-α, IL-6), and autophagy-related proteins (LC3II and p62) were assessed. Furthermore, the effect of PTGS1 manipulation on autophagy in endocardial endothelial cells (EECs) was examined using cell transfection experiments.Results: PTGS1 expression was significantly higher in LAA tissues of AF (+) T (+) patients compared to AF (+) T (-) and SR groups. It was positively correlated with reduced LAA emptying velocity (LAAEV), higher CHA2DS2-VASc scores, and elevated platelet activation markers (MPA, sCD40L, and d-dimer). Data also showed increased M1 macrophage infiltration and higher pro-inflammatory cytokines (IL-1β, TNF-α, IL-6) in AF (+) T (+) patients, with PTGS1 expression strongly linked to these markers. Furthermore, PTGS1 overexpression inhibited autophagy in EECs by decreasing LC3II/LC3I ratio and increasing p62 levels, while PTGS1 knockdown promoted autophagy, protecting against endothelial dysfunction.Conclusions: PTGS1 is overexpressed in AF patients with thrombosis and may play an important role in promoting thrombus formation through enhanced platelet activation, inflammation, and inhibition of autophagy.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"254-265"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Female sex as risk factor for undertreatment: need for a paradigm shift in the care of atrial fibrillation and ischaemic disease. 女性性别作为治疗不足的危险因素：需要在房颤和缺血性疾病的护理范式转变。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-05-01 Epub Date: 2025-01-16 DOI: 10.1080/00015385.2025.2453790

Bernadette Corica, Davide Antonio Mei, Giuseppe Boriani

引用次数: 0

Fifteen years of experience with the melody^™ TPV for percutaneous pulmonary valve replacement. 15年的melody™TPV经皮肺瓣膜置换术经验。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-05-01 Epub Date: 2025-02-10 DOI: 10.1080/00015385.2025.2459453

Cools Bjorn, Pieter De Meester, Werner Budts, Ruth Heying, Alexander Vande Bruaene, Derize Boshoff, Anouk Depypere, Stephen Brown, Marc Gewillig

{"title":"Fifteen years of experience with the melody™ TPV for percutaneous pulmonary valve replacement.","authors":"Cools Bjorn, Pieter De Meester, Werner Budts, Ruth Heying, Alexander Vande Bruaene, Derize Boshoff, Anouk Depypere, Stephen Brown, Marc Gewillig","doi":"10.1080/00015385.2025.2459453","DOIUrl":"10.1080/00015385.2025.2459453","url":null,"abstract":"Background: The Melody™ TPV has been used as an alternative to surgical pulmonary valve replacement; limited medium-term follow-up data are available.Aims: To report the follow-up data of all Melody™ TPVs implanted locally over a 15-year period (2006-2021).Methods: Single-centre non-randomised prospective observational study of all implanted Melody™ valves in the pulmonary position.Results: 234 Melody™ valves were implanted at a mean age of 20.8 ± 24.6y. Indications for valve implantation included: pulmonary stenosis (47.2%,) regurgitation (30.9%), and mixed pathology (21.9%). The implant zone substrate consisted of homograft in 52.6%, patched right ventricular outflow tract in 33.8%, and bioprostheses in 13.6% of the cases. Valve survival at 10 years was 89% and 72% at 15 years follow-up. Pulmonary stenosis and pulmonary and tricuspid valve regurgitation demonstrated no significant evolution over the 15-year follow-up. Over the study period, there were 7 deaths at a mean age of 54.2 ± 21.1y; none was valve related. Valve failure was observed in 22 cases (9.4%), mainly due to endocarditis 13/22 (59.0%). The overall incidence of endocarditis was 1.5% per patient-year and occurred in 10.2% (n = 24) of patients 2.7 ± 1.6y after TPV, mostly in younger men (median 18.3, range 8.1 - 49.5 y). Balloon dilatation to accommodate for somatic growth was successful in all 17 (7.3%) attempted cases.Conclusion: The Melody™ valve had a low risk for valve failure with overall well-preserved valve function over up to 15 years of follow-up. Endocarditis remains a concern. The Melody™ valve is competitive with other surgical and percutaneous conduits.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"237-244"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The association between peak tricuspid regurgitation velocity and 1-year heart failure readmission in hospitalised patients with heart failure with preserved ejection fraction. 射血分数保留型心力衰竭住院患者的三尖瓣反流峰值速度与 1 年心力衰竭再入院之间的关系。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-05-01 Epub Date: 2024-11-19 DOI: 10.1080/00015385.2024.2421638

Tianbo Wang, Xiaohan Liu, Yue Zhang, Chenli Fang, Junbo Xu

{"title":"The association between peak tricuspid regurgitation velocity and 1-year heart failure readmission in hospitalised patients with heart failure with preserved ejection fraction.","authors":"Tianbo Wang, Xiaohan Liu, Yue Zhang, Chenli Fang, Junbo Xu","doi":"10.1080/00015385.2024.2421638","DOIUrl":"10.1080/00015385.2024.2421638","url":null,"abstract":"Background: This study aimed to evaluate the association between peak tricuspid regurgitation velocity (TRV) and 1-year heart failure (HF) readmission in hospitalised patients with HF with preserved ejection fraction (HFpEF) because the impact of peak TRV on the short-term prognosis of these patients has been unclear.Methods: From January 2020 to December 2021, 513 hospitalised HFpEF patients age ≥ 60 years with 1-year follow-up were included in this study. Peak TRV was classified as normal (≤ 2.8 m/s) and high (> 2.8 m/s) value according to pulmonary hypertension probability.Results: Approximately 68.23% of HFpEF patients had a high peak TRV value. In the final adjusted Cox regression model, peak TRV was still independently associated with HF readmission (HR: 1.74, 95% CI: 1.19-2.55, p = 0.004). Furthermore, patients with high peak TRV were also associated with an increased risk of HF readmission (HR: 2.30, 95% CI: 1.31-4.04, p = 0.004), compared to those with normal peak TRV. After inverse probability of weighting, the risk of HF readmission in patients with high peak TRV was 2.53 (95% CI: 1.35-4.75, p = 0.004) compared to those with normal peak TRV. Additionally, Subgroup analysis revealed very elderly patients, male, and patients with hypertension had a significantly worse prognosis.Conclusion: Peak TRV is independently associated with HF readmission in hospitalised HFpEF patients. High peak TRV has a higher risk of HF readmission in patients age ≥ 80 years, male and patients with hypertension, indicating that special attention should be paid to these patients.","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"217-224"},"PeriodicalIF":2.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142666824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First-in-man concomitant mitral transcatheter edge-to-edge repair and atrial fibrillation ablation. 二尖瓣经导管边缘对边缘修复和房颤消融的首次合并。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-05-01 Epub Date: 2025-02-26 DOI: 10.1080/00015385.2025.2471651

Kyriakos Dimitriadis, Stergios Soulaidopoulos, Nikolaos Pyrpyris, Eirini Beneki, Dimitrios Tsiachris, Konstantinos Aznaouridis, Konstantina Aggeli, Konstantinos Tsioufis

引用次数: 0

Severe tricuspid regurgitation and right heart failure secondary to carcinoid heart disease. 继发于类癌心脏病的严重三尖瓣反流和右心衰竭。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-05-01 Epub Date: 2024-08-29 DOI: 10.1080/00015385.2024.2396757

Cian Murray, James Mannion, Mark Wilkinson

引用次数: 0

Staging cardiac damage in aortic stenosis: stratifying prognosis to individualise the treatment. 主动脉瓣狭窄的心脏损害分期：分层预后以个体化治疗。

IF 2.1 4区医学

Acta cardiologica Pub Date : 2025-05-01 Epub Date: 2025-01-25 DOI: 10.1080/00015385.2025.2457178

Tommaso Viva, Simona Sperlongano, Mai-Linh Nguyen Trung, Hélène Petitjean, Patrizio Lancellotti

引用次数: 0