Investigation of the relationship between TIMI frame count, Tp-E interval duration and Tp-E/QT ratio in patients with ST elevation myocardial infarction.

IF 2.5 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Murat Erdem Alp, Mustafa Feridun Koşar, Ece Çelebi Coşkun
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引用次数: 0

Abstract

Background: TIMI (Thrombolysis In Myocardial Infarction) frame count is a quantitative method that objectively assesses slow coronary blood flow. In our study, corrected TIMI frame count and non-invasive parameters such as Tp-e interval and Tp-e/QT ratio were investigated after revascularization in patients with ST Elevation Myocardial Infarction (STEMI).

Methods: Patients who were admitted to our hospital with a preliminary diagnosis of STEMI between January 2020 and July 2020 were included in our study. From coronary angiography views, post-procedure corrected TIMI frame counts were measured. Pre and post-procedure Tp-e interval and Tp-e/QT ratios from ECGs were recorded. The patients were divided into 2 groups based on the corrected TIMI frame count of 27. TP-e interval and Tp-e/QT ratios between these two groups were examined.

Results: When the changes in corrected TIMI frame counts and Tp-e interval time were compared, an inverse correlation was found between the changes in Tp-e interval time and corrected TIMI frame count (r= -0.349; p = 0.001). Similarly, an inverse correlation was observed in the change in the Tp-e/QT ratio (r= -0.343; p = 0.002). Patients were divided into 2 groups based on the corrected TIMI frame count (upper limit value of 27). There was a significant difference between the two groups in terms of Tp-e interval (p = 0.003; p < 0.01) and Tp-e/QT ratios (p = 0.023; p < 0.05) measured in the 90th minute ECGs after revascularization.

Conclusions: Coronary antegrade blood flow can be demonstrated invasively by the non-invasive parameters TP-e interval and Tpe/QT ratio instead of corrected TIMI frame count.

ST段抬高型心肌梗死患者TIMI帧数、Tp-E间期时间及Tp-E/QT比值关系的研究
背景:TIMI (Thrombolysis In Myocardial Infarction,心肌梗死溶栓)框架计数是一种客观评估冠状动脉血流缓慢的定量方法。在我们的研究中,对ST段抬高型心肌梗死(STEMI)患者血运重建术后经校正的TIMI框架计数和非侵入性参数,如Tp-e间期和Tp-e/QT比值进行了研究。方法:将2020年1月至2020年7月期间初步诊断为STEMI的患者纳入我们的研究。从冠状动脉造影角度,测量手术后校正的TIMI框架计数。记录术前和术后心电图的Tp-e间期和Tp-e/QT比值。根据校正后的TIMI帧数27分为两组。观察两组间TP-e间期及TP-e /QT比值。结果:将校正后的TIMI帧数与Tp-e间隔时间的变化进行比较,发现Tp-e间隔时间的变化与校正后的TIMI帧数呈负相关(r= -0.349; p = 0.001)。同样,Tp-e/QT比值的变化也呈负相关(r= -0.343; p = 0.002)。根据校正后的TIMI帧数(上限为27)将患者分为两组。两组间Tp-e间期(p = 0.003; p)和Tp-e/QT比值(p = 0.023; p)差异有统计学意义。结论:冠脉顺行血流可通过Tp-e间期和Tpe/QT比值等无创参数,而非经校正的TIMI帧计数来判断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Acta cardiologica
Acta cardiologica 医学-心血管系统
CiteScore
2.50
自引率
12.50%
发文量
115
审稿时长
2 months
期刊介绍: Acta Cardiologica is an international journal. It publishes bi-monthly original, peer-reviewed articles on all aspects of cardiovascular disease including observational studies, clinical trials, experimental investigations with clear clinical relevance and tutorials.
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