HALP评分对冠状动脉分叉病变患者行双支架治疗的长期临床结果的影响。

IF 2.5 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Hicaz Zencirkıran Ağuş, Serkan Kahraman, Sezgin Atmaca, İrem Türkmen, Mehmet Çiçek, Erhan Melikoğlu, Hasan Şahin, Abidin Emre Tırnaksız, Doğukan Salduz, Yusuf Karadağ, Mehmet Altunova, Ali Kemal Kalkan, Mehmet Ertürk
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引用次数: 0

摘要

目的:经皮冠状动脉介入治疗冠状动脉分叉病变(CBL)是一种具有挑战性的病变。最近,血红蛋白、白蛋白、淋巴细胞、血小板指数(HALP)已被用于确定许多疾病的预后,并提供有关患者营养状况和全身性炎症的宝贵信息。我们的研究旨在评估HALP对接受真冠状动脉分叉支架植入术(CBS)患者的长期主要不良心脏事件(MACE)的影响。方法:回顾性分析773例接受经皮冠状动脉介入治疗的真非左主干CBL患者。主要临床终点是MACE defıned作为靶病变血运重建术(TLR)、靶血管心肌梗死(TVMI)或心脏死亡率的发生。次要终点是支架内血栓形成(ST)。根据HALP评分的最佳临界值31.891分,将研究样本分为两组。结果:HALP评分与MACE发生风险呈负相关。结论:我们的研究结果表明,HALP评分是冠状动脉分叉支架术患者长期majör不良心血管事件的重要独立预测因子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of HALP score on long-term clinical outcomes in patients with coronary bifurcation lesion undergoing 2-stent strategy.

Objectives: Percutaneous coronary interventions (PCI) of coronary bifurcation lesions (CBL) are challenging lesions. Recently haemoglobin, albumin, lymphocyte, platelet index (HALP), has been used to determine the prognosis of many diseases and gives valuable information about the patient's nutritional status and systemic inflammation. Our study aimed to assess the impact of HALP on long-term major advers cardiac events (MACE) for patients undergoing true coronary bifurcation stenting (CBS) procedure.

Methods: A total of 773 patients who underwent percutaneous coronary intervention for true non-left main CBL were retrospectively enrolled. The primary clinical endpoint was MACE defıned as the occurence of target lesion revascularization (TLR), target vessel myocardial infarction (TVMI) or cardiac mortality. Secondary endpoint was stent thrombosis (ST). According to the best cut-off value of HALP score of 31.891, the study samples were divided into two groups.

Results: HALP score was negatively associated with the risk of MACE. Compared with patients whose HALP scores were >31.891, those who had HALP scores <31.891 seemed to have a high risk of MACE. In multivariate regression analysis HALP and CRP were determined as independent predictors of MACE. Kaplan-Meier survival curve analysis showed that the higher HALP group had a significantly better event-free survival regarding the occurrence of MACE, TVMI, TLR and cardiac mortality.

Conclusion: Our study's findings indicate that, HALP score was a significant independent predictor of long-term majör advers cardiovascular events in patients undergoing coronary artery bifurcation stenting procedure.

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来源期刊
Acta cardiologica
Acta cardiologica 医学-心血管系统
CiteScore
2.50
自引率
12.50%
发文量
115
审稿时长
2 months
期刊介绍: Acta Cardiologica is an international journal. It publishes bi-monthly original, peer-reviewed articles on all aspects of cardiovascular disease including observational studies, clinical trials, experimental investigations with clear clinical relevance and tutorials.
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