Acta cardiologica最新文献

{"title":"Silent threat: navigating subacute cardiac tamponade following atrial fibrillation ablation.","authors":"Cristian Castillo-Rodriguez, Douglas Andres Salguero-Lopez, Deephak Swaminath","doi":"10.1080/00015385.2025.2493973","DOIUrl":"https://doi.org/10.1080/00015385.2025.2493973","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of successful percutaneous balloon mitral valvotomy on aortic elastic properties in mitral stenosis.","authors":"M Sudhakar Rao, Sravan K Reddy, Kanhai Lalani, Sree Madhurya Reddy","doi":"10.1080/00015385.2025.2493975","DOIUrl":"https://doi.org/10.1080/00015385.2025.2493975","url":null,"abstract":"<p><p><b>Background:</b> Aortic elastic properties in mitral stenosis have not been much studied. To date, only a few studies have studied the effect of percutaneous balloon mitral valvotomy (BMV) on aortic elastic properties. This was the first study done in Indian subcontinent in a tertiary care hospital in South India studying the effect of BMV on aortic stiffness in severe rheumatic mitral stenosis. We studied the relationship between aortic elastic properties and mitral stenosis and the effect of BMV on the same. <b>Results:</b> A total of thirty-two patients satisfying the criteria for severe mitral stenosis underwent balloon mitral valvotomy. All parameters were compared with age and sex-matched healthy volunteers. Aortic elastic properties were assessed by aortic strain and aortic stiffness index (ASI). The aortic strain was significantly higher in the patients with mitral stenosis 24-48 h after BMV, whereas the ASI was significantly lower. There was a significant decrease in mitral mean gradient and systolic pulmonary artery pressure after BMV. Mitral valve area significantly increased after BMV. <b>Conclusions:</b> Aortic elastic properties, as assessed by aortic stiffness, are usually impaired in patients with mitral stenosis, which improves following balloon mitral valvotomy.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-7"},"PeriodicalIF":2.1,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum and dietary fatty acids and their relationship to vascular inflammation and carotid intima-media thickness: implications for cardiovascular risk in patients with arterial hypertension.","authors":"Georgina N Marchiori, María E Paqualini, David Flores, María F Triquell, María J Moreira-Espinoza, Aldo R Eynard, Mirta A Valentich, María D Defagó","doi":"10.1080/00015385.2025.2493978","DOIUrl":"https://doi.org/10.1080/00015385.2025.2493978","url":null,"abstract":"<p><strong>Background: </strong>Pathogenic mechanisms involved in arterial hypertension (HT) promote the atherosclerosis development. Fatty acids (FAs) could modulate these processes. We investigated the association between dietary and serum FAs and early atherosclerosis development and their correlation with serum vascular inflammation markers in HT.</p><p><strong>Methods: </strong>96 patients were included. Dietary information was collected through a validated food frequency questionnaire. Serum FAs were detected by gas chromatography. High-sensitivity C-reactive protein (hs-CRP), interleukin 6 (IL-6) and fibrinogen serum were determined by immunoturbidimetry, enzyme immunoassay and Clauss method, respectively. Carotid intima media-thickness (cIMT) was determined by ultrasound. Multivariate linear regression models were applied.</p><p><strong>Results: </strong>Patients showed an adverse health profile, with high caloric intake (3113 ± 1477 kcal/day), LDL cholesterol (126.0 ± 35.1 mg/dL), and overweight (BMI 31.1 ± 5.5 kg/t2), and also an inflam-matory process, characterised by higher hs-CRP (3.9 ± 2.7 mg/L) and fibrinogen (433.4 ± 84.6 mg/dL) concentrations. We found significant inverse correlations between dietary monounsaturated FAs (MUFAs), serum omega-3 polyunsaturated FAs (n-3 PUFAs), and hs-CRP (<i>β</i> = -3.59, [95% CI -6.87 to -0.32], <i>p</i> = 0.03 and <i>β</i> = -0.70, [95% CI -1.42-0.01], <i>p</i> = 0.05, respectively), significant positive associations between dietary MUFAs, serum saturated FAs (SFAs) and cIMT (<i>β</i> = 81.96, [95% CI 33.42-130.50], <i>p</i> = 0.002 and <i>β</i> = 36.71, [95% CI 6.34-67.08], <i>p</i> = 0.02, respectively), and significant inverse correlations between serum omega-6 polyunsaturated FAs (n-6 PUFAs) and cIMT (<i>β</i> = -91.44, [95% CI -168.01 to -14.88], <i>p</i> = 0.02 and <i>β</i> = -41.01, [95% CI -70.73-11.28], <i>p</i> = 0.01).</p><p><strong>Conclusions: </strong>Serum n-3 PUFAs modulate hs-CRP levels, while n-6 PUFAs suggest antiatherosclerotic properties in HT. The ambiguous impact of MUFAs requires comprehensive research.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-8"},"PeriodicalIF":2.1,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare spontaneous closure of a coronary pulmonary artery fistula: a case report.","authors":"Shuyi Hu, Hua Yan, Yafeng He, Handong Zhu","doi":"10.1080/00015385.2025.2493972","DOIUrl":"https://doi.org/10.1080/00015385.2025.2493972","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-3"},"PeriodicalIF":2.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of lipid lowering therapy intensification in very high risk patients with dyslipidaemia eligible for PCSK9 monoclonal antibodies: 1-year outcomes of the PERI-DYS study.","authors":"Klaus G Parhofer, David Pittrow, Andreas L Birkenfeld, Uwe Fraass, Bernd Hohenstein, Carsten Siegert, Jens Klotsche, Elisabeth Steinhagen-Thiessen, Stefan Dexl, Volker J J Schettler, Ulrich Laufs","doi":"10.1080/00015385.2025.2490381","DOIUrl":"https://doi.org/10.1080/00015385.2025.2490381","url":null,"abstract":"<p><strong>Purpose: </strong>The PERI-DYS study evaluates patients at very high cardiovascular (CV) risk, including those who receive PCSK9 monoclonal antibodies (PCSK9-mAb) and those who are eligible for PCSK9-mAb but do not receive them.</p><p><strong>Methods: </strong>This is a prospective observational registry at 70 sites in Germany, categorising patients by PCSK9-mAb treatment status at baseline. LDL cholesterol (LDL-C) changes and factors influencing lipid-lowering therapy (LLT) intensification were assessed after one year. Identifier: ClinicalTrials.gov NCT03110432.</p><p><strong>Results: </strong>Among 1565 patients, LDL-C levels decreased from 91.0 mg/dL at baseline to 73.5 mg/dL at 6 months and 71.5 mg/dL at 12 months. A total of 33.1% achieved the LDL-C goal (<55 mg/dL) according to EAS/ESC dyslipidaemia guidelines, with achievement rates ranging from 16.3% in those without PCSK9-mAb and statins to 50.5% in those on combined PCSK9-mAb, statins, and/or ezetimibe. Lipid intensity changed in 22.3% of patients, with 14.8% experiencing intensification and 9.3% reduction. Significant predictors of LLT intensification included younger age (odds ratio (OR) for 60+ years 0.73), no baseline ezetimibe (OR 0.43), LDL-C > 100 mg/dL (OR 3.90), and statin intolerance (OR 0.68).</p><p><strong>Conclusions: </strong>Despite eligibility for PCSK9-mAb treatment and management by specialised physicians, most patients did not reach the LDL-C target, and LLT intensification was rare. This suggests an underutilisation of available treatments, highlighting a gap in the management of high CV risk patients.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haemostatic changes and outcomes in transcatheter aortic valve implantation.","authors":"Mai-Linh Nguyen Trung, Adriana Postolache, Hélène Petitjean, Mathieu Lempereur, Laurent Davin, Tommaso Viva, Cécile Oury, Raluca Dulgheru, Patrizio Lancellotti","doi":"10.1080/00015385.2025.2491157","DOIUrl":"https://doi.org/10.1080/00015385.2025.2491157","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-12"},"PeriodicalIF":2.1,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143952488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of the FIB-4 index in ST-elevation myocardial infarction patients: from admission to follow-up.","authors":"Ayşe İrem Demirtola, Anar Mammadli, Gökhan Çiçek","doi":"10.1080/00015385.2025.2493977","DOIUrl":"https://doi.org/10.1080/00015385.2025.2493977","url":null,"abstract":"<p><strong>Background: </strong>ST-elevation myocardial infarction (STEMI) remains a leading cause of global mortality despite advancements in primary percutaneous coronary intervention (PCI). The fibrosis-4 (FIB-4) index, a non-invasive marker of liver fibrosis, has been associated with cardiovascular outcomes. However, its predictive value for in-hospital and post-discharge all-cause mortality in STEMI patients undergoing PCI remains uncertain. This study aimed to evaluate the prognostic utility of the FIB-4 index in this high-risk population.</p><p><strong>Methods: </strong>This retrospective study analysed 2186 STEMI patients who underwent PCI. Patients were categorised into three groups based on FIB-4 tertiles: Group 1 (FIB-4 < 4.52), group 2 (4.52 ≤ FIB-4 < 6.07), and group 3 (FIB-4 ≥ 6.07). Logistic regression assessed predictors of in-hospital mortality, while Kaplan-Meier's survival analysis and Cox proportional hazards models were used to evaluate post-discharge mortality.</p><p><strong>Results: </strong>In-hospital mortality was significantly higher in group 3 (4.3%) compared to group 2 and group 1 (<i>p</i> = .016). The FIB-4 index was an independent predictor of in-hospital mortality (OR: 1.105, 95% CI: 1.011-1.207, <i>p</i> = .028), alongside Killip class ≥ II, diabetes mellitus and reduced eGFR < 76.8 mL/min. During a median follow-up of 21 months post-discharge, all-cause mortality occurred in 8% of patients (<i>n</i> = 178), with rates highest in group 3 (10%, <i>n</i> = 74) compared to group 2 and group 1 (<i>p</i> = .002). Kaplan-Meier's survival analysis demonstrated significantly lower cumulative survival in group 3 (log-rank test, <i>p</i> = .003). Multivariable Cox analysis confirmed an increased post-discharge mortality risk in group 3 (HR: 1.862, 95% CI: 1.254-2.764, <i>p</i> = .002) compared to group 1.</p><p><strong>Conclusions: </strong>The FIB-4 index independently predicts in-hospital and post-discharge all-cause mortality in STEMI patients undergoing PCI. Its integration into clinical practice could improve risk stratification and patient management.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-7"},"PeriodicalIF":2.1,"publicationDate":"2025-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the heart eat along? A two years lifestyle intervention in shift workers.","authors":"Christine Binder-Mendl, Thorsten Schwerte, Wolfgang Marktl","doi":"10.1080/00015385.2025.2484847","DOIUrl":"https://doi.org/10.1080/00015385.2025.2484847","url":null,"abstract":"<p><strong>Background: </strong>The present study investigates whether it is possible to reduce heart rate by nutritional information and lifestyle modification.</p><p><strong>Methods: </strong>In this exploratory study 18 male rotating shift workers (39.7 ± 7.5 y) were randomly divided into two groups by using the urn model. At the beginning of the study, all subjects wore a heart rate sensor for 24 hours during a night shift. This recording was repeated after 1 year, when groups switched, and at the end of the study. Participants received nutritional information every other month for 1 year. The nutritional counseling was provided by a dietician/nutritionist and only contained information about healthy eating. By using the food diaries, nutritional errors were uncovered and could easily be corrected. Subjects were also encouraged to incorporate more endurance and resistance training into their daily routines.</p><p><strong>Results: </strong>After the intervention, heart rate in group A decreased during the day from 75 ± 6.3 beats per minute (bpm) before to 73 ± 7.5 bpm afterward and during the night from 72 ± 9.8 bpm before to 70 ± 9.5 bpm afterward. In group B heart rate increased during the day from 72 ± 9.1 bpm before to 76 ± 7.2 bpm afterward and decreased at night from 69 ± 10.0 bpm before to 66 ± 11.2 bpm afterward. All values were highly significant (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>Motivation to adopt a better lifestyle in terms of healthy eating and daily exercise could be a cost-effective contribution to heart health among rotating shift workers. However, the individually adapted interventions need to occur more frequently.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-9"},"PeriodicalIF":2.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of postoperative pain and quality of life between left anterior thoracotomy and median sternotomy off-pump coronary artery bypass surgery in multivessel coronary revascularization: a retrospective study of a case series of 356 consecutive patients.","authors":"Xiujun Chen, Yong Lin, Liangwan Chen, Xiaofu Dai, Zhiqin Lin","doi":"10.1080/00015385.2025.2491152","DOIUrl":"https://doi.org/10.1080/00015385.2025.2491152","url":null,"abstract":"<p><strong>Background: </strong>This study compared post-operative pain and quality of life (QoL) between left anterior thoracotomy (LAT) and median sternotomy (MS) in off-pump coronary artery bypass grafting (OPCAB). LAT is a less invasive alternative to MS for the treatment of advanced coronary artery disease.</p><p><strong>Methods: </strong>This retrospective study analysed 356 patients who underwent OPCAB for multivessel revascularization between January 2018 and April 2023. Patients were divided into LAT (<i>n</i> = 169) and MS (<i>n</i> = 187) groups. Postoperative pain was measured using a Visual Analog Scale (VAS). QoL was assessed using the Short Form-36 (SF-36) questionnaire preoperatively and postoperatively.</p><p><strong>Results: </strong>Patients with LAT had significantly lower pain scores on postoperative days 1, 3, and 7 (<i>p</i> < 0.001) than those with MS. LAT was associated with shorter ICU and hospital stay (<i>p</i> = 0.011 and <i>p</i> < 0.001, respectively). The QoL scores for physical domains were higher in the LAT group at 1 and 3 months post-surgery (<i>p</i> < 0.01). No significant differences were observed in the mental health domains between groups.</p><p><strong>Conclusions: </strong>LAT for multivessel OPCAB is associated with reduced postoperative pain, shorter hospital stay, and improved early QoL, particularly in physical domains, compared to MS. These findings suggest that LAT is a preferable option for suitable patients, promoting faster recovery and better early postoperative outcomes.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-11"},"PeriodicalIF":2.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143951974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced image reconstruction algorithm keeps reducing the radiation dose needed for CT calcium scoring.","authors":"Alain Nchimi","doi":"10.1080/00015385.2025.2490398","DOIUrl":"https://doi.org/10.1080/00015385.2025.2490398","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"1-2"},"PeriodicalIF":2.1,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}