Acta cardiologicaPub Date : 2025-06-01Epub Date: 2024-10-10DOI: 10.1080/00015385.2024.2412372
Muhammad Osama, Safiyyah Ubaid, Ubaid Ullah, Maryam Ubaid
{"title":"Pulmonary artery pulsatility index as a prognostic marker in heart failure with preserved ejection fraction.","authors":"Muhammad Osama, Safiyyah Ubaid, Ubaid Ullah, Maryam Ubaid","doi":"10.1080/00015385.2024.2412372","DOIUrl":"10.1080/00015385.2024.2412372","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"425-426"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2025-06-01Epub Date: 2025-04-20DOI: 10.1080/00015385.2025.2493977
Ayşe İrem Demirtola, Anar Mammadli, Gökhan Çiçek
{"title":"Predictive value of the FIB-4 index in ST-elevation myocardial infarction patients: from admission to follow-up.","authors":"Ayşe İrem Demirtola, Anar Mammadli, Gökhan Çiçek","doi":"10.1080/00015385.2025.2493977","DOIUrl":"10.1080/00015385.2025.2493977","url":null,"abstract":"<p><strong>Background: </strong>ST-elevation myocardial infarction (STEMI) remains a leading cause of global mortality despite advancements in primary percutaneous coronary intervention (PCI). The fibrosis-4 (FIB-4) index, a non-invasive marker of liver fibrosis, has been associated with cardiovascular outcomes. However, its predictive value for in-hospital and post-discharge all-cause mortality in STEMI patients undergoing PCI remains uncertain. This study aimed to evaluate the prognostic utility of the FIB-4 index in this high-risk population.</p><p><strong>Methods: </strong>This retrospective study analysed 2186 STEMI patients who underwent PCI. Patients were categorised into three groups based on FIB-4 tertiles: Group 1 (FIB-4 < 4.52), group 2 (4.52 ≤ FIB-4 < 6.07), and group 3 (FIB-4 ≥ 6.07). Logistic regression assessed predictors of in-hospital mortality, while Kaplan-Meier's survival analysis and Cox proportional hazards models were used to evaluate post-discharge mortality.</p><p><strong>Results: </strong>In-hospital mortality was significantly higher in group 3 (4.3%) compared to group 2 and group 1 (<i>p</i> = .016). The FIB-4 index was an independent predictor of in-hospital mortality (OR: 1.105, 95% CI: 1.011-1.207, <i>p</i> = .028), alongside Killip class ≥ II, diabetes mellitus and reduced eGFR < 76.8 mL/min. During a median follow-up of 21 months post-discharge, all-cause mortality occurred in 8% of patients (<i>n</i> = 178), with rates highest in group 3 (10%, <i>n</i> = 74) compared to group 2 and group 1 (<i>p</i> = .002). Kaplan-Meier's survival analysis demonstrated significantly lower cumulative survival in group 3 (log-rank test, <i>p</i> = .003). Multivariable Cox analysis confirmed an increased post-discharge mortality risk in group 3 (HR: 1.862, 95% CI: 1.254-2.764, <i>p</i> = .002) compared to group 1.</p><p><strong>Conclusions: </strong>The FIB-4 index independently predicts in-hospital and post-discharge all-cause mortality in STEMI patients undergoing PCI. Its integration into clinical practice could improve risk stratification and patient management.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"387-393"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2025-06-01Epub Date: 2025-02-10DOI: 10.1080/00015385.2025.2460402
Bülent Özlek, Süleyman Barutçu
{"title":"Right heart and heart failure with preserved ejection fraction: the dark side of the moon.","authors":"Bülent Özlek, Süleyman Barutçu","doi":"10.1080/00015385.2025.2460402","DOIUrl":"10.1080/00015385.2025.2460402","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"427-428"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2025-06-01Epub Date: 2025-03-11DOI: 10.1080/00015385.2025.2476890
Ramazan Aslan, Murat Özmen, Faik Özel, Erhan Arıkan, İsa Ardahanlı
{"title":"Enhancing the evidence base: constructive feedback on the comparative effectiveness of torsemide and furosemide in heart failure.","authors":"Ramazan Aslan, Murat Özmen, Faik Özel, Erhan Arıkan, İsa Ardahanlı","doi":"10.1080/00015385.2025.2476890","DOIUrl":"10.1080/00015385.2025.2476890","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"432-433"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2025-06-01Epub Date: 2025-02-22DOI: 10.1080/00015385.2025.2469001
Davide Antonio Mei, Matteo Martella, Giuseppe Boriani
{"title":"The intriguing relationships between atrial fibrillation and heart failure: insights from cardiac implantable electronic devices.","authors":"Davide Antonio Mei, Matteo Martella, Giuseppe Boriani","doi":"10.1080/00015385.2025.2469001","DOIUrl":"10.1080/00015385.2025.2469001","url":null,"abstract":"","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"429-431"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143475918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta cardiologicaPub Date : 2025-06-01Epub Date: 2025-04-14DOI: 10.1080/00015385.2025.2491151
Jingyi Lin, Lin Zhang, Shuaishuai Deng, Boxuan Feng, Li Liu, Guanwei Fan
{"title":"Ratio of red blood cell distribution width to albumin: a predictive biomarker of In-hospital mortality in heart failure patients.","authors":"Jingyi Lin, Lin Zhang, Shuaishuai Deng, Boxuan Feng, Li Liu, Guanwei Fan","doi":"10.1080/00015385.2025.2491151","DOIUrl":"10.1080/00015385.2025.2491151","url":null,"abstract":"<p><strong>Background: </strong>The ratio of red blood cell distribution width (RDW) to albumin (ALB), known as RAR, functions as an innovative indicator related to prognosis. However, whether RAR can predict the in-hospital mortality (IHM) for heart failure (HF) patients remains ambiguous.</p><p><strong>Methods: </strong>This study included HF patients derived from the Medical Information Mart for Intensive Care III (MIMIC-III) and IV (MIMIC-IV) databases. To examine the association between RAR and IHM, multiple Logistic regression models were conducted, complemented by subgroup analyses. Additionally, to ascertain the optimal threshold for RAR, restricted cubic spline (RCS) regressions were applied.</p><p><strong>Results: </strong>In the MIMIC-III (<i>n</i> = 9,413) and MIMIC-IV (<i>n</i> = 18,685) HF cohorts, the incidence of IHM was observed in 1,639 (17.41%) and 1,175 (6.29%) participants. Following adjustment for various covariates, RAR was shown to correlate with IHM (OR, 1.45 [95% CI, 1.08-1.39]). The areas under the curves for RAR were 0.683 (MIMIC-III) and 0.710 (MIMIC-IV), indicating superior predictive value than RDW and ALB. In subgroup analysis, younger HF patients with diabetes and without atrial fibrillation or anaemia showed higher ORs than older patients without diabetes or atrial fibrillation and those with anaemia, respectively. RCS indicated the OR for RAR was non-linear with IHM, and the optimal threshold for RAR prediction was between 4.5 and 5.</p><p><strong>Conclusion: </strong>An elevated RAR correlates with an increased risk of IHM in HF patients. Given that RAR can be readily derived from routine laboratory tests, it holds potential as a novel biomarker for identifying high-risk HF patients.</p>","PeriodicalId":6979,"journal":{"name":"Acta cardiologica","volume":" ","pages":"376-386"},"PeriodicalIF":2.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}